Torsten Steinmetzer

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 26

Top Topics

Venous Thromboembolism

Crystal Structure

Top Venues

Journal of medicinal chemistry

Archiv der Pharmazie

This page only lists publications with an associated author ORCID identifier.

Publications

Simon Huber, Niklas J Braun, Luna C Schmacke, Robin Murra, Daniela Ploen, Eberhard Hildt, Andreas Heine, Torsten Steinmetzer
Synthesis and structural characterization of new macrocyclic inhibitors of the Zika virus NS2B-NS3 protease. Archiv der Pharmazie 357 (9) (2024)
Roman W Lange, Konstantin Bloch, Miriam Ruth Heindl, Jan Wollenhaupt, Manfred S Weiss, Katharina Häussermann, Gerhard Klebe, Franco H Falcone, Eva Böttcher-Friebertshäuser, Sven O Dahms, Torsten Steinmetzer
Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors. ChemMedChem 19 (9) (2024)
Roman W Lange, Konstantin Bloch, Miriam Ruth Heindl, Jan Wollenhaupt, Manfred S Weiss, Katharina Häussermann, Gerhard Klebe, Franco H Falcone, Eva Böttcher-Friebertshäuser, Sven O Dahms, Torsten Steinmetzer
Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors. ChemMedChem (2024)
Ashley Anzet van Niekerk, Sara Maluck, Patrik Mag, Csaba Kővágó, Ádám Kerek, Ákos Jerzsele, Torsten Steinmetzer, Erzsébet Pászti-Gere
Antiviral Drug Candidate Repositioning for Streptococcus suis Infection in Non-Tumorigenic Cell Models. Biomedicines 12 (4) (2024)
Ashley Anzet van Niekerk, Sara Maluck, Patrik Mag, Csaba Kővágó, Ádám Kerek, Ákos Jerzsele, Torsten Steinmetzer, Erzsébet Pászti-Gere
Antiviral Drug Candidate Repositioning for Streptococcus suis Infection in Non-Tumorigenic Cell Models. Biomedicines 12 (4) (2024)
Simon Huber, Niklas J Braun, Luna C Schmacke, Robin Murra, Daniela Ploen, Eberhard Hildt, Andreas Heine, Torsten Steinmetzer
Synthesis and structural characterization of new macrocyclic inhibitors of the Zika virus NS2B-NS3 protease. Archiv der Pharmazie (2024)
Simon J A Wiedemeyer, Guojie Wu, T L Phuong Pham, Heike Lang-Henkel, Benjamin Perez Urzua, James C Whisstock, Ruby H P Law, Torsten Steinmetzer
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. ChemMedChem 18 (6) (2023)
Simon J A Wiedemeyer, Guojie Wu, T L Phuong Pham, Heike Lang-Henkel, Benjamin Perez Urzua, James C Whisstock, Ruby H P Law, Torsten Steinmetzer
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. ChemMedChem 18 (6) (2023)
Simon J A Wiedemeyer, Guojie Wu, T L Phuong Pham, Heike Lang-Henkel, Benjamin Perez Urzua, James C Whisstock, Ruby H P Law, Torsten Steinmetzer
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. ChemMedChem (2023)
Simon J A Wiedemeyer, Guojie Wu, T L Phuong Pham, Heike Lang-Henkel, Benjamin Perez Urzua, James C Whisstock, Ruby H P Law, Torsten Steinmetzer
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. ChemMedChem 18 (6) (2023)
Simon J A Wiedemeyer, Guojie Wu, T L Phuong Pham, Heike Lang-Henkel, Benjamin Perez Urzua, James C Whisstock, Ruby H P Law, Torsten Steinmetzer
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. ChemMedChem 18 (6) (2023)
Niklas J Braun, Simon Huber, Luna C Schmacke, Andreas Heine, Torsten Steinmetzer
Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease. ChemMedChem (2022)
Simon Huber, Niklas J Braun, Luna C Schmacke, Jun Ping Quek, Robin Murra, Daniela Bender, Eberhard Hildt, Dahai Luo, Andreas Heine, Torsten Steinmetzer
Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. Journal of medicinal chemistry 65 (9) (2022)
Anna Sandner, Khang Ngo, Johannes Schiebel, Angela Ilse Marca Pizarroso, Linda Schmidt, Benjamin Wenzel, Torsten Steinmetzer, Andreas Ostermann, Andreas Heine, Gerhard Klebe
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin. Journal of medicinal chemistry 64 (3) (2021)
Sven O Dahms, Tanja Haider, Gerhard Klebe, Torsten Steinmetzer, Katharina Häussermann
OFF-State-Specific Inhibition of the Proprotein Convertase Furin. ACS chemical biology 16 (9) (2021)
Erzsébet Pásztiné Gere, Judit Mercédesz Pomothy, Ákos Jerzsele, Oliver Pilgram, Torsten Steinmetzer
Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Thomas Schmitz, Ajay Abisheck Paul George, Britta Nubbemeyer, Charlotte A Bäuml, Torsten Steinmetzer, Oliver Ohlenschlãger, Arijit Biswas, Diana Imhof
NMR-Based Structural Characterization of a Two-Disulfide-Bonded Analogue of the FXIIIa Inhibitor Tridegin: New Insights into Structure-Activity Relationships. International journal of molecular sciences 22 (2) (2021)
Marvin Korff, Lukas Imberg, Jonas M Will, Nico Bückreiß, Svetlana A Kalinina, Benjamin M Wenzel, Gregor A Kastner, Constantin Gabriel Daniliuc, Maximilian Barth, Ruzanna A Ovsepyan, Kirill R Butov, Hans-Ulrich Humpf, Matthias Lehr, Mikhail A Panteleev, Antti Poso, Uwe Karst, Torsten Steinmetzer, Gerd Bendas, Dmitrii V Kalinin
Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action. Journal of medicinal chemistry 63 (21) (2020)
Niklas J Braun, Jun P Quek, Simon Huber, Jenny Kouretova, Dorothee Rogge, Heike Lang-Henkel, Ezekiel Z K Cheong, Bing L A Chew, Andreas Heine, Dahai Luo, Torsten Steinmetzer
Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses. ChemMedChem 15 (15) (2020)
Anna Sandner, Tobias Hüfner-Wulsdorf, Andreas Heine, Torsten Steinmetzer, Gerhard Klebe
Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. Journal of medicinal chemistry 62 (21) (2019)
Charlotte A Bäuml, Thomas Schmitz, Ajay Abisheck Paul George, Monica Sudarsanam, Kornelia Hardes, Torsten Steinmetzer, Lori A Holle, Alisa S Wolberg, Bernd Pötzsch, Johannes Oldenburg, Arijit Biswas, Diana Imhof
Coagulation Factor XIIIa Inhibitor Tridegin: On the Role of Disulfide Bonds for Folding, Stability, and Function. Journal of medicinal chemistry 62 (7) (2019)
Torsten Steinmetzer, Oliver Pilgram, Benjamin M Wenzel, Simon J A Wiedemeyer
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding. Journal of medicinal chemistry 63 (4) (2019)
Thuy Van Lam van, Teodora Ivanova, Kornelia Hardes, Miriam Ruth Heindl, Rory E Morty, Eva Böttcher-Friebertshäuser, Iris Lindberg, Manuel E Than, Sven O Dahms, Torsten Steinmetzer
Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin. ChemMedChem 14 (6) (2019)
Kornelia Hardes, Teodora Ivanova, Bastian Thaa, Gerald M McInerney, Tove Irene Klokk, Kirsten Sandvig, Sebastian Künzel, Iris Lindberg, Torsten Steinmetzer
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin. ChemMedChem 12 (8) (2017)
Teodora Ivanova, Kornelia Hardes, Stephanie Kallis, Sven O Dahms, Manuel E Than, Sebastian Künzel, Eva Böttcher-Friebertshäuser, Iris Lindberg, Guan-Sheng Jiao, Ralf Bartenschlager, Torsten Steinmetzer
Optimization of Substrate-Analogue Furin Inhibitors. ChemMedChem 12 (23) (2017)
Judit Pomothy, Gergely Szombath, Patrik Rokonál, Gábor Mátis, Zsuzsanna Neogrády, Torsten Steinmetzer, Erzsébet Pászti-Gere
The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models. BioMed research international 2016 (2016)
Wegderes Endreas, Jana Brüßler, Doru Vornicescu, Michael Keusgen, Udo Bakowsky, Torsten Steinmetzer
Thrombin-Inhibiting Anticoagulant Liposomes: Development and Characterization. ChemMedChem 11 (3) (2015)