Wiep Klaas Smits (W K Smits)

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Venues

Clinical microbiology reviews

mSphere

Antibiotics (Basel, Switzerland)

ACS infectious diseases

Leiden University Medical Center

University of Groningen (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leiden University Medical Center

Netherlands

Associate Professor :: Department of Medical Microbiology

Leiden University Medical Center

Netherlands

Assistant professor :: Department of Medical Microbiology

Leiden University Medical Center

Netherlands

Principal investigator :: Department of Medical Microbiology

Leiden University Medical Center

Netherlands

Postdoctoral associate :: Department of Medical Microbiology

Massachusetts Institute of Technology

United States

Postdoctoral associate/fellow :: Biology

Education History

University of Groningen

Netherlands

PHD :: Faculty of Mathematics and Natural Sciences

University of Groningen

Netherlands

MSC :: Department of Genetics

Publications

Abbas Yadegar, Haggai Bar-Yoseph, Tanya Marie Monaghan, Sepideh Pakpour, Andrea Severino, Ed J Kuijper, Wiep Klaas Smits, Elisabeth M Terveer, Sukanya Neupane, Ali Nabavi-Rad, Javad Sadeghi, Giovanni Cammarota, Gianluca Ianiro, Estello Nap-Hill, Dickson Leung, Karen Wong, Dina H Kao
Fecal microbiota transplantation: current challenges and future landscapes. Clinical microbiology reviews 37 (2) (2024)
Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Florence M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost J Willemse, Christopher A Hitchcock, Johan G C van Hasselt, Tanja Schneider, Nathaniel I Martin
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Science translational medicine 16 (759) (2024)
Jeroen Corver, Bart Claushuis, Tatiana M Shamorkina, Arnoud H de Ru, Merle M van Leeuwen, Paul J Hensbergen, Wiep Klaas Smits
Proteolytic activity of surface-exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile. Molecular microbiology (2024)
Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Florence M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost J Willemse, Christopher A Hitchcock, Johan G C van Hasselt, Tanja Schneider, Nathaniel I Martin
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Science translational medicine 16 (759) (2024)
Abbas Yadegar, Haggai Bar-Yoseph, Tanya Marie Monaghan, Sepideh Pakpour, Andrea Severino, Ed J Kuijper, Wiep Klaas Smits, Elisabeth M Terveer, Sukanya Neupane, Ali Nabavi-Rad, Javad Sadeghi, Giovanni Cammarota, Gianluca Ianiro, Estello Nap-Hill, Dickson Leung, Karen Wong, Dina H Kao
Fecal microbiota transplantation: current challenges and future landscapes. Clinical microbiology reviews (2024)
Abbas Yadegar, Haggai Bar-Yoseph, Tanya Marie Monaghan, Sepideh Pakpour, Andrea Severino, Ed J Kuijper, Wiep Klaas Smits, Elisabeth M Terveer, Sukanya Neupane, Ali Nabavi-Rad, Javad Sadeghi, Giovanni Cammarota, Gianluca Ianiro, Estello Nap-Hill, Dickson Leung, Karen Wong, Dina H Kao
Fecal microbiota transplantation: current challenges and future landscapes. Clinical microbiology reviews 37 (2) (2024)
Abbas Yadegar, Haggai Bar-Yoseph, Tanya Marie Monaghan, Sepideh Pakpour, Andrea Severino, Ed J Kuijper, Wiep Klaas Smits, Elisabeth M Terveer, Sukanya Neupane, Ali Nabavi-Rad, Javad Sadeghi, Giovanni Cammarota, Gianluca Ianiro, Estello Nap-Hill, Dickson Leung, Karen Wong, Dina H Kao
Fecal microbiota transplantation: current challenges and future landscapes. Clinical microbiology reviews 37 (2) (2024)
Abbas Yadegar, Haggai Bar-Yoseph, Tanya Marie Monaghan, Sepideh Pakpour, Andrea Severino, Ed J Kuijper, Wiep Klaas Smits, Elisabeth M Terveer, Sukanya Neupane, Ali Nabavi-Rad, Javad Sadeghi, Giovanni Cammarota, Gianluca Ianiro, Estello Nap-Hill, Dickson Leung, Karen Wong, Dina H Kao
Fecal microbiota transplantation: current challenges and future landscapes. Clinical microbiology reviews 37 (2) (2024)
Ishani Wickramage, Zhong Peng, Soumyadeep Chakraborty, Céline Harmanus, Ed J Kuijper, Sally Alrabaa, Wiep Klaas Smits, Xingmin Sun
The vanR Cd Mutation 343A>G, Resulting in a Thr115Ala Substitution, Is Associated with an Elevated Minimum Inhibitory Concentration (MIC) of Vancomycin in Clostridioides difficile Clinical Isolates from Florida. Microbiology spectrum (2023)
Bart Claushuis, Arnoud H de Ru, Sarah A Rotman, Peter A van Veelen, Lisa F Dawson, Brendan W Wren, Jeroen Corver, Wiep Klaas Smits, Paul J Hensbergen
Revised Model for the Type A Glycan Biosynthetic Pathway in Clostridioides difficile Strain 630Δ erm Based on Quantitative Proteomics of cd0241 - cd0244 Mutant Strains. ACS infectious diseases (2023)
Perezimor Etifa, César Rodríguez, Céline Harmanus, Ingrid M J G Sanders, Igor A Sidorov, Olufunmilayo A Mohammed, Emily Savage, Andrew R Timms, Jane Freeman, Wiep Klaas Smits, Mark H Wilcox, Simon D Baines
Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model. Antibiotics (Basel, Switzerland) 12 (3) (2023)
Perezimor Etifa, César Rodríguez, Céline Harmanus, Ingrid M J G Sanders, Igor A Sidorov, Olufunmilayo A Mohammed, Emily Savage, Andrew R Timms, Jane Freeman, Wiep Klaas Smits, Mark H Wilcox, Simon D Baines
Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model. Antibiotics (Basel, Switzerland) 12 (3) (2023)
Wiep Klaas Smits, Yassene Mohammed, Arnoud H de Ru, Valentina Cordo', Annemieke H Friggen, Peter A van Veelen, Paul J Hensbergen
Clostridioides difficile Phosphoproteomics Shows an Expansion of Phosphorylated Proteins in Stationary Growth Phase. mSphere 7 (1) (2022)
Ana M Oliveira Paiva, Annemieke H Friggen, Roxanne Douwes, Bert Wittekoek, Wiep Klaas Smits
Practical observations on the use of fluorescent reporter systems in Clostridioides difficile. Antonie van Leeuwenhoek 115 (2) (2022)
Fijs W B van Leeuwen, Nikolas Duszenko, Danny M van Willigen, Wiep Klaas Smits, Tessa Buckle, Meta Roestenberg, Fijs W B van Leeuwen
Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice. Bioconjugate chemistry 32 (3) (2021)
A Baktash, Jeroen Corver, C Harmanus, Wiep Klaas Smits, W Fawley, M H Wilcox, N Kumar, D W Eyre, A Indra, A Mellmann, Ed J Kuijper
Comparison of Whole-Genome Sequence-Based Methods and PCR Ribotyping for Subtyping of Clostridioides difficile. Journal of clinical microbiology 60 (2) (2021)
Ilse M Boekhoud, Igor Sidorov, Sam Nooij, Céline Harmanus, Ingrid M J G Bos-Sanders, Virginie Viprey, William Spittal, Emma Clark, Kerrie Davies, Jane Freeman, Ed J Kuijper, Wiep Klaas Smits, null null
Haem is crucial for medium-dependent metronidazole resistance in clinical isolates of Clostridioides difficile. The Journal of antimicrobial chemotherapy 76 (7) (2021)
Ilse M Boekhoud, Bastian V H Hornung, Eloísa Sevilla, Céline Harmanus, Ingrid M J G Bos-Sanders, Elisabeth M Terveer, Rosa Bolea, Jeroen Corver, Ed J Kuijper, Wiep Klaas Smits
Plasmid-mediated metronidazole resistance in Clostridioides difficile. Nature communications 11 (1) (2020)
Ilse M Boekhoud, Annika-Marisa Michel, Jeroen Corver, Dieter Jahn, Wiep Klaas Smits
Redefining the Clostridioides difficile σB Regulon: σB Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide. mSphere 5 (5) (2020)
Ana M Oliveira Paiva, Leen de Jong, Annemieke H Friggen, Wiep Klaas Smits, Jeroen Corver
The C-Terminal Domain of Clostridioides difficile TcdC Is Exposed on the Bacterial Cell Surface. Journal of bacteriology 202 (22) (2020)
Fijs W B van Leeuwen, Clarize M de Korne, Silvia J Spa, Danny M van Willigen, Albertus W Hensbergen, Anton Bunschoten, Nikolas Duszenko, Wiep Klaas Smits, Meta Roestenberg, Fijs W B van Leeuwen
Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice. ACS infectious diseases 5 (7) (2019)
Erika van Eijk, Ilse M Boekhoud, Ed J Kuijper, Ingrid M J G Bos-Sanders, George Wright, Wiep Klaas Smits
Genome Location Dictates the Transcriptional Response to PolC Inhibition in Clostridium difficile. Antimicrobial agents and chemotherapy 63 (2) (2019)
Frank Fleurbaaij, Alex A Henneman, Jeroen Corver, Cornelis W Knetsch, Wiep Klaas Smits, Sjoerd T Nauta, Martin A Giera, Irina Dragan, Nitin Kumar, Trevor D Lawley, Aswin Verhoeven, Hans C van Leeuwen, Ed J Kuijper, Paul J Hensbergen
Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans. Scientific reports 8 (1) (2018)
Erika van Eijk, Vasileios Paschalis, Matthew Green, Annemieke H Friggen, Marilynn A Larson, Keith Spriggs, Geoffrey S Briggs, Panos Soultanas, Wiep Klaas Smits
Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile. Open biology 6 (12) (2017)

Wiep Klaas Smits.css-eqlu8i{font-size:small;padding-left:4px;} (W K Smits)

Publication Activity (10 Years)

Top Topics

Top Venues

Wiep Klaas Smits (W K Smits)