Mario van der Stelt

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 38

Top Topics

Structural Basis

Methicillin Resistant Staphylococcus Aureus

Top Venues

Journal of the American Chemical Society

Journal of medicinal chemistry

Nature communications

Chembiochem : a European journal of chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Ming Jiang, Mirjam C W Huizenga, Florian Mohr, Avand Amedi, Renze Bakker, Richard J B H N van den Berg, Hui Deng, Tom van der Wel, Constant A A van Boeckel, Mario van der Stelt
Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors. Journal of medicinal chemistry 67 (14) (2024)
Ming Jiang, Mirjam C W Huizenga, Florian Mohr, Avand Amedi, Renze Bakker, Richard J B H N van den Berg, Hui Deng, Tom van der Wel, Constant A A van Boeckel, Mario van der Stelt
Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors. Journal of medicinal chemistry 67 (14) (2024)
Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Florence M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost J Willemse, Christopher A Hitchcock, Johan G C van Hasselt, Tanja Schneider, Nathaniel I Martin
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Science translational medicine 16 (759) (2024)
Ming Jiang, Mirjam C W Huizenga, Florian Mohr, Avand Amedi, Renze Bakker, Richard J B H N van den Berg, Hui Deng, Tom van der Wel, Constant A A van Boeckel, Mario van der Stelt
Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors. Journal of medicinal chemistry 67 (14) (2024)
Ming Jiang, Mirjam C W Huizenga, Florian Mohr, Avand Amedi, Renze Bakker, Richard J B H N van den Berg, Hui Deng, Tom van der Wel, Constant A A van Boeckel, Mario van der Stelt
Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors. Journal of medicinal chemistry (2024)
Alexander T Bakker, Ioli Kotsogianni, Mariana Avalos, Jeroen M Punt, Bing Liu, Diana Piermarini, Berend Gagestein, Cornelis J Slingerland, Le Zhang, Joost J Willemse, Leela B Ghimire, Richard J H B N van den Berg, Antonius P A Janssen, Tom H M Ottenhoff, Constant A A van Boeckel, Gilles P van Wezel, Dmitry Ghilarov, Nathaniel I Martin, Mario van der Stelt
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nature chemistry (2024)
Laura V De Paus, Yu An, Antonius P A Janssen, Richard J B H N van den Berg, Laura H Heitman, Mario van der Stelt
Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB 2 Receptor. Chembiochem : a European journal of chemical biology 25 (7) (2024)
Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Florence M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost J Willemse, Christopher A Hitchcock, Johan G C van Hasselt, Tanja Schneider, Nathaniel I Martin
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Science translational medicine 16 (759) (2024)
Laura V De Paus, Yu An, Antonius P A Janssen, Richard J B H N van den Berg, Laura H Heitman, Mario van der Stelt
Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB 2 Receptor. Chembiochem : a European journal of chemical biology 25 (7) (2024)
Ming Jiang, Mirjam C W Huizenga, Florian Mohr, Avand Amedi, Renze Bakker, Richard J B H N van den Berg, Hui Deng, Tom van der Wel, Constant A A van Boeckel, Mario van der Stelt
Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors. Journal of medicinal chemistry 67 (14) (2024)
Laura V De Paus, Yu An, Antonius P A Janssen, Richard J B H N van den Berg, Laura H Heitman, Mario van der Stelt
Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB 2 Receptor. Chembiochem : a European journal of chemical biology (2024)
Xiaoting Li, Hao Chang, Jara Bouma, Laura V De Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu, Yanan Yu, Richard J B H N van den Berg, Antonius P A Janssen, Aron Lichtman, Zhi-Jie Liu, Pal Pacher, Mario van der Stelt, Laura H Heitman, Tian Hua
Structural basis of selective cannabinoid CB 2 receptor activation. Nature communications 14 (1) (2023)
Xiaoting Li, Hao Chang, Jara Bouma, Laura V De Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu, Yanan Yu, Richard J B H N van den Berg, Antonius P A Janssen, Aron Lichtman, Zhi-Jie Liu, Pal Pacher, Mario van der Stelt, Laura H Heitman, Tian Hua
Structural basis of selective cannabinoid CB 2 receptor activation. Nature communications 14 (1) (2023)
Xiaoting Li, Hao Chang, Jara Bouma, Laura V De Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu, Yanan Yu, Richard J B H N van den Berg, Antonius P A Janssen, Aron Lichtman, Zhi-Jie Liu, Pal Pacher, Mario van der Stelt, Laura H Heitman, Tian Hua
Structural basis of selective cannabinoid CB 2 receptor activation. Nature communications 14 (1) (2023)
Ming Jiang, Mirjam C W Huizenga, Jonah L Wirt, Janos Paloczi, Avand Amedi, Richard J B H N van den Berg, Joerg Benz, Ludovic Collin, Hui Deng, Xinyu Di, Wouter F Driever, Bogdan I Florea, Uwe Grether, Antonius P A Janssen, Thomas Hankemeier, Laura H Heitman, Tsang-Wai Lam, Florian Mohr, Anto Pavlovic, Iris Ruf, Helma van den Hurk, Anna F Stevens, Daan van der Vliet, Tom van der Wel, Matthias B Wittwer, Constant A A van Boeckel, Pal Pacher, Andrea G Hohmann, Mario van der Stelt
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence. Nature communications 14 (1) (2023)
Jeroen M Punt, Daan van der Vliet, Mario van der Stelt
Chemical Probes to Control and Visualize Lipid Metabolism in the Brain. Accounts of chemical research 55 (22) (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society 145 (2) (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society 145 (2) (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society 145 (2) (2022)
Berend Gagestein, Johannes H von Hegedus, Joanneke C Kwekkeboom, Marieke Heijink, Niek Blomberg, Tom van der Wel, Bogdan I Florea, Hans van den Elst, Kim Wals, Herman S Overkleeft, Martin A Giera, René E M Toes, Andreea Ioan-Facsinay, Mario van der Stelt
Comparative Photoaffinity Profiling of Omega-3 Signaling Lipid Probes Reveals Prostaglandin Reductase 1 as a Metabolic Hub in Human Macrophages. Journal of the American Chemical Society 144 (41) (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society 145 (2) (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society 145 (2) (2022)
Alexander T Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M Straub, Mariana Avalos, Richard J B H N van den Berg, Bogdan I Florea, Gilles P van Wezel, Antonius P A Janssen, Nathaniel I Martin, Mario van der Stelt
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA. Journal of the American Chemical Society 145 (2) (2022)
Susanne Prokop, Péter Ábrányi-Balogh, Benjámin Barti, Márton Vámosi, Miklós Zöldi, László Barna, Gabriella M Urbán, András Dávid Tóth, Barna Dudok, Attila Egyed, Hui Deng, Gian Marco Leggio, László Hunyady, Mario van der Stelt, György Miklós Keserű, István Katona
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells. Nature communications 12 (1) (2021)
Elliot D Mock, Mohammed Mustafa, Ozge Gunduz-Cinar, Resat Cinar, Gavin N Petrie, Vasudev Kantae, Xinyu Di, Daisuke Ogasawara, Zoltan V Varga, Janos Paloczi, Cristina Miliano, Giulia Donvito, Annelot C M van Esbroeck, Anouk M F van der Gracht, Ioli Kotsogianni, Joshua K Park, Andrea Martella, Tom van der Wel, Marjolein Soethoudt, Ming Jiang, Tiemen J Wendel, Antonius P A Janssen, Alexander T Bakker, Colleen M Donovan, Laura I Castillo, Bogdan I Florea, Jesse Wat, Helma van den Hurk, Matthias Wittwer, Uwe Grether, Andrew Holmes, Constant A A van Boeckel, Thomas Hankemeier, Benjamin F Cravatt, Matthew W Buczynski, Matthew N Hill, Pal Pacher, Aron H Lichtman, Mario van der Stelt
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice. Nature chemical biology 16 (6) (2020)
Tom van der Wel, Riet Hilhorst, Hans den Dulk, Tim van den Hooven, Nienke M Prins, Joost A P M Wijnakker, Bogdan I Florea, Eelke B Lenselink, Gerard van Westen, Rob Ruijtenbeek, Herman S Overkleeft, Allard Kaptein, Tjeerd Barf, Mario van der Stelt
Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis. Nature communications 11 (1) (2020)
Zach W B Armstrong, Chi-Lin Kuo, Daniël Lahav, Bing Liu, Rachel Johnson, Thomas J M Beenakker, Casper de Boer, Chung-Sing Wong, Erwin R van Rijssel, Marjoke F Debets, Bogdan I Florea, Colin Hissink, Rolf G Boot, Paul P Geurink, Huib Ovaa, Mario van der Stelt, Jeroen D C Codée, Jeroen D C Codée, Johannes M F G Aerts, Liang Wu, Herman S Overkleeft, Gideon J Davies
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. Journal of the American Chemical Society 142 (30) (2020)
Sebastiaan T A Koenders, Eva J van Rooden, Hans van den Elst, Bogdan I Florea, Herman S Overkleeft, Mario van der Stelt
STA-55, an Easily Accessible, Broad-Spectrum, Activity-Based Aldehyde Dehydrogenase Probe. Chembiochem : a European journal of chemical biology 21 (13) (2020)
Roman C Sarott, Matthias V Westphal, Patrick Pfaff, Claudia Korn, David A Sykes, Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Marie Weise, Yelena Mostinski, Pattarin Hompluem, Eline Koers, Tamara Miljuš, Nicolas J Roth, Hermon Asmelash, Man C Vong, Jacopo Piovesan, Wolfgang Guba, Arne C Rufer, Eric A Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A Zirwes, Anja Osterwald, Anto Pavlovic, Svenja Moes, Jennifer Beck, Irene Benito-Cuesta, Teresa Grande, Samuel Ruiz de Martı N Esteban, Alexei Yeliseev, Faye Drawnel, Gabriella Widmer, Daniela Holzer, Tom van der Wel, Harpreet Mandhair, Cheng-Yin Yuan, William R Drobyski, Yurii Saroz, Natasha L Grimsey, Michael Honer, Jürgen Fingerle, Klaus Gawrisch, Julian Romero, Cecilia J Hillard, Zoltan V Varga, Mario van der Stelt, Pal Pacher, Jürg Gertsch, Peter J McCormick, Christoph Ullmer, Sergio Oddi, Mauro Maccarrone, Dmitry B Veprintsev, Marc Nazare, Uwe Grether, Erick M Carreira
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells. Journal of the American Chemical Society 142 (40) (2020)
Juan Zhou, Elliot D Mock, Karol Al Ayed, Xinyu Di, Vasudev Kantae, Lindsey Burggraaff, Anna F Stevens, Andrea Martella, Florian Mohr, Ming Jiang, Tom van der Wel, Tiemen J Wendel, Tim P Ofman, Yvonne Tran, Nicky de Koster, Gerard van Westen, Thomas Hankemeier, Mario van der Stelt
Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family. Journal of medicinal chemistry 63 (17) (2020)
Antonius P A Janssen, Jacob M A van Hengst, Olivier J M Béquignon, Hui Deng, Gerard J P van Westen, Mario van der Stelt
Structure Kinetics Relationships and Molecular Dynamics Show Crucial Role for Heterocycle Leaving Group in Irreversible Diacylglycerol Lipase Inhibitors. Journal of medicinal chemistry 62 (17) (2019)
Juan Zhou, Elliot D Mock, Andrea Martella, Vasudev Kantae, Xinyu Di, Lindsey Burggraaff, Marc P Baggelaar, Karol Al-Ayed, Alexander Bakker, Bogdan I Florea, Sebastian H Grimm, Hans den Dulk, Chun T Li, Laura Mulder, Herman S Overkleeft, Thomas Hankemeier, Gerard J P van Westen, Mario van der Stelt
Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI. ACS chemical biology 14 (2) (2019)
Marc P Baggelaar, Hans den Dulk, Bogdan I Florea, Domenico Fazio, Nicola Bernabò, Marcello Raspa, Antonius P A Janssen, Ferdinando Scavizzi, Barbara Barboni, Hermen S Overkleeft, Mauro Maccarrone, Mario van der Stelt
ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction. ACS chemical biology 14 (10) (2019)
Marc P Baggelaar, Hans den Dulk, Bogdan I Florea, Domenico Fazio, Davide Perruzza, Nicola Bernabò, Marcello Raspa, Antonius P A Janssen, Ferdinando Scavizzi, Barbara Barboni, Hermen S Overkleeft, Mauro Maccarrone, Mario van der Stelt
ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction. ACS chemical biology 14 (12) (2019)
Antonius P A Janssen, Sebastian H Grimm, Ruud H M Wijdeven, Eelke B Lenselink, Jacques Neefjes, Constant A A van Boeckel, Gerard J P van Westen, Mario van der Stelt
Drug Discovery Maps, a Machine Learning Model That Visualizes and Predicts Kinome-Inhibitor Interaction Landscapes. Journal of chemical information and modeling 59 (3) (2018)
Ming Jiang, Mario van der Stelt
Activity-Based Protein Profiling Delivers Selective Drug Candidate ABX-1431, a Monoacylglycerol Lipase Inhibitor, To Control Lipid Metabolism in Neurological Disorders. Journal of medicinal chemistry 61 (20) (2018)
Annelot C M van Esbroeck, Antonius P A Janssen, Armand B Cognetta, Daisuke Ogasawara, Guy Shpak, Mark van der Kroeg, Vasudev Kantae, Marc P Baggelaar, Femke M S de Vrij, Hui Deng, Marco Allarà, Filomena Fezza, Zhanmin Lin, Tom van der Wel, Marjolein Soethoudt, Elliot D Mock, Hans den Dulk, Ilse L Baak, Bogdan I Florea, Giel Hendriks, Luciano De Petrocellis, Herman S Overkleeft, Thomas Hankemeier, Chris I De Zeeuw, Vincenzo Di Marzo, Mauro Maccarrone, Benjamin F Cravatt, Steven A Kushner, Mario van der Stelt
Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474. Science (New York, N.Y.) 356 (6342) (2018)