Xaralabos Varelas

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 23

Top Venues

Nature communications

Journal of experimental & clinical cancer research : CR

Proceedings of the National Academy of Sciences of the United States of America

eLife

Boston University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Boston University

United States

Associate Professor :: Biochemistry

Publications

Ahmed A Raslan, Tho X Pham, Jisu Lee, Konstantinos Kontodimas, Andrew M Tilston-Lunel, Jillian Schmottlach, Jeongmin Hong, Taha Dinc, Andreea M Bujor, Nunzia Caporarello, Aude Thiriot, Ulrich H von Andrian, Steven K Huang, Roberto F Nicosia, Maria Trojanowska, Xaralabos Varelas, Giovanni Ligresti
Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis. Nature communications 15 (1) (2024)
Ahmed A Raslan, Tho X Pham, Jisu Lee, Konstantinos Kontodimas, Andrew M Tilston-Lunel, Jillian Schmottlach, Jeongmin Hong, Taha Dinc, Andreea M Bujor, Nunzia Caporarello, Aude Thiriot, Ulrich H von Andrian, Steven K Huang, Roberto F Nicosia, Maria Trojanowska, Xaralabos Varelas, Giovanni Ligresti
Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis. Nature communications 15 (1) (2024)
Ahmed A Raslan, Tho X Pham, Jisu Lee, Konstantinos Kontodimas, Andrew M Tilston-Lunel, Jillian Schmottlach, Jeongmin Hong, Taha Dinc, Andreea M Bujor, Nunzia Caporarello, Aude Thiriot, Ulrich H von Andrian, Steven K Huang, Roberto F Nicosia, Maria Trojanowska, Xaralabos Varelas, Giovanni Ligresti
Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis. Nature communications 15 (1) (2024)
Ahmed A Raslan, Tho X Pham, Jisu Lee, Konstantinos Kontodimas, Andrew M Tilston-Lunel, Jillian Schmottlach, Jeongmin Hong, Taha Dinc, Andreea M Bujor, Nunzia Caporarello, Aude Thiriot, Ulrich H von Andrian, Steven K Huang, Roberto F Nicosia, Maria Trojanowska, Xaralabos Varelas, Giovanni Ligresti
Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis. Nature communications 15 (1) (2024)
Anthony N Federico, Joseph G Kern, Xaralabos Varelas, Stephano Monti
Structure Learning for Gene Regulatory Networks. PLoS computational biology 19 (5) (2023)
Boting Ning, Andrew M Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E Lenburg, Jennifer E Beane, Xaralabos Varelas
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. Journal of experimental & clinical cancer research : CR 42 (1) (2023)
Boting Ning, Andrew M Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E Lenburg, Jennifer E Beane, Xaralabos Varelas
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. Journal of experimental & clinical cancer research : CR 42 (1) (2023)
Boting Ning, Andrew M Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E Lenburg, Jennifer E Beane, Xaralabos Varelas
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. Journal of experimental & clinical cancer research : CR 42 (1) (2023)
Boting Ning, Andrew M Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E Lenburg, Jennifer E Beane, Xaralabos Varelas
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. Journal of experimental & clinical cancer research : CR 42 (1) (2023)
Marc A Vittoria, Nathan Kingston, Kristyna Kotynkova, Eric Xia, Rui Hong, Lee Huang, Shayna McDonald, Andrew M Tilston-Lunel, Revati Darp, Joshua D Campbell, Deborah Lang, Xiaowei Xu, Yvonne J K Edwards, Xaralabos Varelas, Neil J Ganem
Inactivation of the Hippo tumor suppressor pathway promotes melanoma. Nature communications 13 (1) (2022)
Joseph G Kern, Andrew M Tilston-Lunel, Anthony N Federico, Boting Ning, Amy Mueller, Grace B Peppler, Eleni Stampouloglou, Nan Cheng, Randy L Johnson, Marc E Lenburg, Jennifer E Beane-Ebel, Stephano Monti, Xaralabos Varelas
Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas. Nature communications 13 (1) (2022)
Nabil Rabhi, Kathleen Desevin, Anna C Belkina, Andrew Tilston-Lunel, Xaralabos Varelas, Matthew D Layne, Stephen R Farmer
Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors. Life science alliance 5 (5) (2022)
Thabet Alhousami, Michael Diny, Faiza Ali, Jennifer Shin, Gaurav Kumar, Vikas Kumar, Joshua D Campbell, Vikki Noonan, Glenn J Hanna, Gerald V Denis, Stephano Monti, Maria A Kukuruzinska, Xaralabos Varelas, Manish V Bais
Inhibition of LSD1 Attenuates Oral Cancer Development and Promotes Therapeutic Efficacy of Immune Checkpoint Blockade and YAP/TAZ Inhibition. Molecular cancer research : MCR 20 (5) (2022)
Andrew Tilston-Lunel, Sarah Mazzilli, Nathan M Kingston, Aleksander D Szymaniak, Julia B Berthet, Joseph G Kern, Kristine Abo, Mary E Reid, Catalina Perdomo, Andrew A Wilson, Avrum Spira, Jennifer Beane, Xaralabos Varelas
Aberrant epithelial polarity cues drive the development of precancerous airway lesions. Proceedings of the National Academy of Sciences of the United States of America 118 (18) (2021)
Andrew J Haak, Enis Kostallari, Delphine Sicard, Giovanni Ligresti, Kyoung Moo Choi, Nunzia Caporarello, Dakota L Jones, Qi Tan, Jeffrey Meridew, Ana M Diaz Espinosa, Aja Aravamudhan, Jessica L Maiers, Rodney D Britt, Anja C Roden, Christina M Pabelick, Y S Prakash, Seyed Mehdi Nouraie, Xiaoyun Li, Yingze Zhang, Daniel J Kass, David Lagares, Andrew M Tager, Xaralabos Varelas, Vijay H Shah, Daniel J Tschumperlin
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis. Science translational medicine 11 (516) (2020)
Anwesha Dey, Xaralabos Varelas, Kun-Liang Guan
Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine. Nature reviews. Drug discovery 19 (7) (2020)
Laertis Ikonomou, Michael J Herriges, Sara L Lewandowski, Robert Marsland, Carlos Villacorta-Martin, Ignacio S Caballero, David B Frank, Reeti M Sanghrajka, Keri Dame, Maciej M Kańduła, Julia B Berthet, Matthew L Lawton, Constantina Christodoulou, Attila J Fabian, Eric Kolaczyk, Xaralabos Varelas, Edward E Morrisey, John M Shannon, Pankaj Mehta, Darrell N Kotton
The in vivo genetic program of murine primordial lung epithelial progenitors. Nature communications 11 (1) (2020)
Eleni Stampouloglou, Nan Cheng, Anthony Federico, Emily Slaby, Stefano Monti, Gregory Lee Szeto, Xaralabos Varelas
Yap suppresses T-cell function and infiltration in the tumor microenvironment. PLoS biology 18 (1) (2020)
Amy Li, Bjoern Chapuy, Xaralabos Varelas, Paola Sebastiani, Stephano Monti
Identification of candidate cancer drivers by integrative Epi-DNA and Gene Expression (iEDGE) data analysis. Scientific reports 9 (1) (2019)
Anatoli B Meriin, Arjun Narayanan, Le Meng, Ilya Alexandrov, Xaralabos Varelas, Ibrahim I Cissé, Michael Y Sherman
Hsp70-Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation. Proceedings of the National Academy of Sciences of the United States of America 115 (30) (2018)
Chih-Sheng Yang, Eleni Stampouloglou, Nathan M Kingston, Liye Zhang, Stefano Monti, Xaralabos Varelas
Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells. EMBO reports 19 (6) (2018)
Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu, Julia B Berthet, Mark-Anthony Bray, Yashaswi Shrestha, Xaralabos Varelas, Jesse S Boehm, Anne E Carpenter
Systematic morphological profiling of human gene and allele function via Cell Painting. eLife 6 (2017)
Aleksander D Szymaniak, Rongjuan Mi, Shannon E McCarthy, Adam C Gower, Taylor L Reynolds, Michael Mingueneau, Maria Kukuruzinska, Xaralabos Varelas
The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland. eLife 6 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Xaralabos Varelas