Jesse S Boehm (Jesse Boehm, J S Boehm)

ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 24

Top Venues

Nature communications

Nature biotechnology

Nature genetics

Cancer discovery

Harvard Medical School (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Harvard Medical School

United States

PHD :: Dana-Farber Cancer Instiute

Massachusetts Institute of Technology

United States

BSC :: Biology

Publications

Jesse S Boehm, Tyler Jacks
Radical Collaboration: Reimagining Cancer Team Science. Cancer discovery 14 (4) (2024)
Sean A Misek, Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua M Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G Doench, David E Root, James M McFarland, Rameen Beroukhim, Jesse S Boehm
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications 15 (1) (2024)
Sean A Misek, Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua M Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G Doench, David E Root, James M McFarland, Rameen Beroukhim, Jesse S Boehm
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications 15 (1) (2024)
Jesse S Boehm, Tyler Jacks
Radical Collaboration: Reimagining Cancer Team Science. Cancer discovery 14 (4) (2024)
Sean A Misek, Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua M Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G Doench, David E Root, James M McFarland, Rameen Beroukhim, Jesse S Boehm
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications 15 (1) (2024)
Jesse S Boehm, Tyler Jacks
Radical Collaboration: Reimagining Cancer Team Science. Cancer discovery 14 (4) (2024)
Oana Ursu, James T Neal, Emily K Shea, Pratiksha I Thakore, Livnat Jerby, Lan Nguyen, Danielle Dionne, Celeste Diaz, Julia Bauman, Mariam Mounir Mosaad, Christian Fagre, April Lo, Maria McSharry, Andrew O Giacomelli, Seav Huong Ly, Orit Rozenblatt-Rosen, William C Hahn, Andrew J Aguirre, Alice H Berger, Aviv Regev, Jesse S Boehm
Massively parallel phenotyping of coding variants in cancer with Perturb-seq. Nature biotechnology 40 (6) (2022)
Daniel P Bondeson, Brenton R Paolella, Adhana Asfaw, Michael V Rothberg, Thomas A Skipper, Carly Langan, Gabriel Mesa, Alfredo Gonzalez, Lauren E Surface, Kentaro Ito, Mariya Kazachkova, William N Colgan, Allison Warren, Joshua M Dempster, John Michael Krill-Burger, Maria Ericsson, Andrew A Tang, Iris Fung, Emily S Chambers, Mai Abdusamad, Nancy Dumont, John G Doench, Federica Piccioni, David E Root, Jesse S Boehm, William C Hahn, Michael Mannstadt, James M McFarland, Francisca Vazquez, Todd R Golub
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nature cancer 3 (6) (2022)
Riaz Gillani, Bo Kyung Alex Seong, Jett Crowdis, Jake R Conway, Neekesh V Dharia, Saif Alimohamed, Brian J Haas, Kyuho Han, Jihye Park, Felix Dietlein, Meng Xiao He, Alma Imamovic, Clement Ma, Michael C Bassik, Jesse S Boehm, Francisca Vazquez, Alexander Gusev, David R Liu, Katherine A Janeway, James M McFarland, Kimberly Stegmaier, Eliezer M Van Allen
Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival. Cancer research 81 (15) (2021)
Allison Warren, Yejia Chen, Andrew Jones, Tsukasa Shibue, William C Hahn, Jesse S Boehm, Francisca Vazquez, Aviad Tsherniak, James M McFarland
Global computational alignment of tumor and cell line transcriptional profiles. Nature communications 12 (1) (2021)
Neekesh V Dharia, Guillaume Kugener, Lillian M Guenther, Clare F Malone, Adam D Durbin, Andrew L Hong, Thomas P Howard, Pratiti Bandopadhayay, Caroline S Wechsler, Iris Fung, Allison C Warren, Joshua M Dempster, John Michael Krill-Burger, Brenton R Paolella, Phoebe Moh, Nishant Jha, Andrew Tang, Phillip G Montgomery, Jesse S Boehm, William C Hahn, Charles W M Roberts, James M McFarland, Aviad Tsherniak, Todd R Golub, Francisca Vazquez, Kimberly Stegmaier
A first-generation pediatric cancer dependency map. Nature genetics 53 (4) (2021)
Francisca Vazquez, Jesse S Boehm
The Cancer Dependency Map enables drug mechanism-of-action investigations. Molecular systems biology 16 (7) (2020)
Andrew L Hong, Yuen-Yi Tseng, Jeremiah A Wala, Won-Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles Wm Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William C Hahn
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. eLife 8 (2019)
Yilong Zou, Michael J Palte, Amy A Deik, Haoxin Li, John K Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík, Elizaveta S Leshchiner, Vasanthi S Viswanathan, Sabina Signoretti, Toni K Choueiri, Jesse S Boehm, Bridget K Wagner, John G Doench, Andrew T Chan, Paul A Clemons, Stuart L Schreiber
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nature communications 10 (1) (2019)
Joshua M Dempster, Clare Pacini, Sasha Pantel, Fiona M Behan, Thomas Green, John Michael Krill-Burger, Charlotte M Beaver, Scott T Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G Doench, Kosuke Yusa, Francisca Vazquez, Leopold Parts, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets. Nature communications 10 (1) (2019)
James M McFarland, Zandra V Ho, Guillaume Kugener, Joshua M Dempster, Phillip G Montgomery, Jordan G Bryan, John Michael Krill-Burger, Thomas M Green, Francisca Vazquez, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Aviad Tsherniak
Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration. Nature communications 9 (1) (2018)
Taibo Li, April Kim, Joseph Rosenbluh, Heiko Horn, Liraz Greenfeld, David An, Andrew Zimmer, Arthur Liberzon, Jon Bistline, Ted Natoli, Yang Li, Aviad Tsherniak, Rajiv Narayan, Aravind Subramanian, Ted Liefeld, Bang Wong, Dawn Thompson, Sarah Calvo, Steven A Carr, Jesse S Boehm, Jacob D Jaffe, Jill Mesirov, Nir Hacohen, Aviv Regev, Kasper Lage
GeNets: a unified web platform for network-based genomic analyses. Nature methods 15 (7) (2018)
Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu, Julia B Berthet, Mark-Anthony Bray, Yashaswi Shrestha, Xaralabos Varelas, Jesse S Boehm, Anne E Carpenter
Systematic morphological profiling of human gene and allele function via Cell Painting. eLife 6 (2017)
Viktor A Adalsteinsson, Gavin Ha, Samuel S Freeman, Atish D Choudhury, Daniel G Stover, Heather A Parsons, Gregory Gydush, Sarah C Reed, Denisse Rotem, Justin Rhoades, Denis Loginov, Dimitri Livitz, Daniel Rosebrock, Ignaty Leshchiner, Jaegil Kim, Chip Stewart, Mara Rosenberg, Joshua M Francis, Cheng-Zhong Zhang, Ofir Cohen, Coyin Oh, Huiming Ding, Paz Polak, Max Lloyd, Sairah Mahmud, Karla Helvie, Margaret S Merrill, Rebecca A Santiago, Edward P O'Connor, Seong H Jeong, Rachel Leeson, Rachel M Barry, Joseph F Kramkowski, Zhenwei Zhang, Laura Polacek, Jens G Lohr, Molly Schleicher, Emily Lipscomb, Andrea Saltzman, Nelly M Oliver, Lori Marini, Adrienne G Waks, Lauren C Harshman, Sara M Tolaney, Eliezer M Van Allen, Eric P Winer, Nancy U Lin, Mari Nakabayashi, Mary-Ellen Taplin, Cory M Johannessen, Levi A Garraway, Todd R Golub, Jesse S Boehm, Nikhil Wagle, Gad A Getz, J Christopher Love, Matthew L Meyerson
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. Nature communications 8 (1) (2017)
Robin M Meyers, Jordan G Bryan, James M McFarland, Barbara A Weir, Ann E Sizemore, Han Xu, Neekesh V Dharia, Phillip G Montgomery, Glenn S Cowley, Sasha Pantel, Amy Goodale, Yenarae Lee, Levi D Ali, Guozhi Jiang, Rakela Lubonja, William F Harrington, Matthew Strickland, Ting Wu, Derek C Hawes, Victor A Zhivich, Meghan R Wyatt, Zohra Kalani, Jaime J Chang, Michael Okamoto, Kimberly Stegmaier, Todd R Golub, Jesse S Boehm, Francisca Vazquez, David E Root, William C Hahn, Aviad Tsherniak
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. Nature genetics 49 (12) (2017)
Uri Ben-David, Gavin Ha, Yuen-Yi Tseng, Noah F Greenwald, Coyin Oh, Juliann Shih, James M McFarland, Bang Wong, Jesse S Boehm, Rameen Beroukhim, Todd R Golub
Patient-derived xenografts undergo mouse-specific tumor evolution. Nature genetics 49 (11) (2017)
Jong Wook Kim, Olga B Botvinnik, Omar Abudayyeh, Chet Birger, Joseph Rosenbluh, Yashaswi Shrestha, Mohamed E Abazeed, Peter S Hammerman, Daniel DiCara, David J Konieczkowski, Cory M Johannessen, Arthur Liberzon, Amir Reza Alizad-Rahvar, Gabriela Alexe, Andrew Aguirre, Mahmoud Ghandi, Heidi Greulich, Francisca Vazquez, Barbara A Weir, Eliezer M Van Allen, Aviad Tsherniak, Diane D Shao, Travis I Zack, Michael Noble, Gad Getz, Rameen Beroukhim, Levi A Garraway, Masoud Ardakani, Chiara Romualdi, Gabriele Sales, David A Barbie, Jesse S Boehm, William C Hahn, Jill P Mesirov, Pablo Tamayo
Characterizing genomic alterations in cancer by complementary functional associations. Nature biotechnology 34 (5) (2016)
Andrew L Hong, Yuen-Yi Tseng, Glenn S Cowley, Oliver Jonas, Jaime H Cheah, Bryan D Kynnap, Mihir B Doshi, Coyin Oh, Stephanie C Meyer, Alanna J Church, Shubhroz Gill, Craig M Bielski, Paula Keskula, Alma Imamovic, Sara Howell, Gregory V Kryukov, Paul A Clemons, Aviad Tsherniak, Francisca Vazquez, Brian D Crompton, Alykhan F Shamji, Carlos Rodriguez-Galindo, Katherine A Janeway, Charles W M Roberts, Kimberly Stegmaier, Paul van Hummelen, Michael J Cima, Robert S Langer, Levi A Garraway, Stuart L Schreiber, David E Root, William C Hahn, Jesse S Boehm
Integrated genetic and pharmacologic interrogation of rare cancers. Nature communications 7 (2016)
Krinio Giannikou, Izabela A Malinowska, Trevor J Pugh, Rachel E Yan, Yuen-Yi Tseng, Coyin Oh, Jaegil Kim, Magdalena E Tyburczy, Yvonne Chekaluk, Yang Liu, Nicola Alesi, Geraldine A Finlay, Chin-Lee Wu, Sabina Signoretti, Matthew Meyerson, Gad Getz, Jesse S Boehm, Elizabeth P Henske, David J Kwiatkowski
Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development. PLoS genetics 12 (8) (2016)
Jens G Lohr, Viktor A Adalsteinsson, Kristian Cibulskis, Atish D Choudhury, Mara Rosenberg, Peter Cruz-Gordillo, Joshua M Francis, Cheng-Zhong Zhang, Alex K Shalek, Rahul Satija, John J Trombetta, Diana Lu, Naren Tallapragada, Narmin Tahirova, Sora Kim, Brendan Blumenstiel, Carrie Sougnez, Alarice Lowe, Bang Wong, Daniel Auclair, Eliezer M Van Allen, Mari Nakabayashi, Rosina T Lis, Gwo-Shu M Lee, Tiantian Li, Matthew S Chabot, Amy Ly, Mary-Ellen Taplin, Thomas E Clancy, Massimo Loda, Aviv Regev, Matthew Meyerson, William C Hahn, Philip W Kantoff, Todd R Golub, Gad Getz, Jesse S Boehm, J Christopher Love
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nature biotechnology 32 (5) (2014)
S E Moody, A C Schinzel, S Singh, F Izzo, M R Strickland, L Luo, S R Thomas, Jesse S Boehm, S Y Kim, Z C Wang, W C Hahn
PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene 34 (16) (2014)

Jesse S Boehm.css-eqlu8i{font-size:small;padding-left:4px;} (Jesse Boehm, J S Boehm)

Publication Activity (10 Years)

Top Topics

Top Venues

Jesse S Boehm (Jesse Boehm, J S Boehm)