Xuankuo Xu

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 20

Top Venues

Biotechnology and bioengineering

mAbs

Biotechnology progress

Biomacromolecules

Bristol-Myers Squibb Co

University of Delaware (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Bristol-Myers Squibb Co Feb 04 2008

United States

Senior Principal Scientist :: Biologics Process Development

Education History

University of Delaware Sep 01 2002 - Feb 01 2008

United States

PHD :: Chemical and Biomolecular Engineering

Publications

Liang-Kai Chu, Ehsan Espah Borujeni, Xuankuo Xu, Sanchayita Ghose, Andrew L Zydney
Comparison of host cell protein removal by depth filters with diatomaceous earth and synthetic silica filter aids using model proteins. Biotechnology and bioengineering (2023)
Chase E Herman, Lie Min, Leila H Choe, Ronald W Maurer, Xuankuo Xu, Sanchayita Ghose, Kelvin H Lee, Abraham M Lenhoff
Analytical characterization of host-cell-protein-rich aggregates in monoclonal antibody solutions. Biotechnology progress (2023)
Seo-Young Park, Susan Egan, Anthony J Cura, Kathryn L Aron, Xuankuo Xu, Mengyuan Zheng, Michael Borys, Sanchayita Ghose, Zheng-Jian Li, Kyongbum Lee
Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction. mAbs 13 (1) (2022)
Ehsan Espah Borujeni, Weixin Jin, Chun Shao, Naresh Chennamsetty, Xuankuo Xu, Sanchayita Ghose
Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody. Antibody therapeutics 5 (4) (2022)
James M Angelo, Kevin Potter, Thomas Müller-Späth, Xuankuo Xu, Zheng-Jian Li, Sanchayita Ghose
Continued insights into virus clearance validation across continuous capture chromatography. Biotechnology and bioengineering 118 (9) (2021)
Jianlin Xu, Shun Zheng, Zeinab Dawood, Charles Hill, Weixin Jin, Xuankuo Xu, Julia Ding, Michael C Borys, Sanchayita Ghose, Zheng-Jian Li, Girish Pendse
Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step. Biotechnology and bioengineering 118 (9) (2021)
Christa L Meingast, Pratik U Joshi, Dylan G Turpeinen, Xuankuo Xu, Melissa Holstein, Hasin Feroz, Swarnim Ranjan, Sanchayita Ghose, Zheng-Jian Li, Caryn L Heidt
Physiochemical properties of enveloped viruses and arginine dictate inactivation. Biotechnology journal 16 (7) (2021)
Zhiqiang Chen, Yueming Qian, Yuanli Song, Xuankuo Xu, Li Tao, Nesredin Mussa, Sanchayita Ghose, Zheng-Jian Li
Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics. mAbs 12 (1) (2021)
Jianlin Xu, Xuankuo Xu, Chao Huang, James M Angelo, Christopher L Oliveira, Mengmeng Xu, Xia Xu, Deniz Temel, Julia Ding, Sanchayita Ghose, Michael C Borys, Zheng-Jian Li
Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study. mAbs 12 (1) (2020)
Zizhuo Xing, Weixin Jin, Xuankuo Xu, Yuanli Song, Chao Huang, Michael C Borys, Sanchayita Ghose, Zheng-Jian Li
A CFD model for predicting protein aggregation in low-pH virial inactivation for mAb production. Biotechnology and bioengineering 117 (11) (2020)
Yi Li, Lye Lin Lock, Jason Mills, Ben S Ou, Marina Morrow, David Stern, Han Wang, Caleb F Anderson, Xuankuo Xu, Sanchayita Ghose, Zheng-Jian Li, Honggang Cui
Selective Capture and Recovery of Monoclonal Antibodies by Self-Assembling Supramolecular Polymers of High Affinity for Protein Binding. Nano letters 20 (10) (2020)
Weixin Jin, Zizhuo Xing, Yuanli Song, Chao Huang, Xuankuo Xu, Sanchayita Ghose, Zheng-Jian Li
Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification. mAbs 11 (8) (2019)
Ruben Wälchli, Mariana Ressurreição, Sebastian Vogg, Fabian Feidl, James M Angelo, Xuankuo Xu, Sanchayita Ghose, Zheng-Jian Li, Xavier Le Saoût, Jonathan Souquet, Hervé Broly, Massimo Morbidelli
Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization. Biotechnology and bioengineering 117 (3) (2019)
James M Angelo, Srinivas Chollangi, Thomas Müller-Späth, Simona Jusyte, Xuankuo Xu, Sanchayita Ghose, Zhengjian Li
Virus clearance validation across continuous capture chromatography. Biotechnology and bioengineering 116 (9) (2019)
Daniel Baur, James M Angelo, Srinivas Chollangi, Thomas Müller-Späth, Xuankuo Xu, Sanchayita Ghose, Zheng-Jian Li, Massimo Morbidelli
Model-assisted process characterization and validation for a continuous two-column protein A capture process. Biotechnology and bioengineering 116 (1) (2018)
Yueming Qian, Zhiqiang Chen, Xin Huang, Xuning Wang, Xuankuo Xu, Stefan Kirov, Richard Ludwig, Nan-Xin Qian, Kandasamy Ravi, Li Tao, Michael C Borys, Zheng-Jian Li
Early identification of unusually clustered mutations and root causes in therapeutic antibody development. Biotechnology and bioengineering 115 (9) (2018)
Jianlin Xu, Matthew S Rehmann, Xuankuo Xu, Chao Huang, Jun Tian, Nan-Xin Qian, Zheng-Jian Li
Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media. mAbs 10 (3) (2018)
Daniel G Greene, Steven J Traylor, Jing Guo, Leila H Choe, Shannon Modla, Xuankuo Xu, Nripen Singh, Lye Lin Lock, Sanchayita Ghose, Zheng-Jian Li, Kelvin H Lee, Norman J Wagner, Abraham M Lenhoff
Mechanisms of precipitate formation during the purification of an Fc-fusion protein. Biotechnology and bioengineering 115 (10) (2018)
Ohnmar Khanal, Nripen Singh, Steven J Traylor, Xuankuo Xu, Sanchayita Ghose, Zheng-Jian Li, Abraham M Lenhoff
Contributions of depth filter components to protein adsorption in bioprocessing. Biotechnology and bioengineering 115 (8) (2018)
Yi Li, Yuzhu Wang, Shih-Hao Ou, Lye Lin Lock, Xuankuo Xu, Sanchayita Ghose, Zheng Jian Li, Honggang Cui
Conformation Preservation of α-Helical Peptides within Supramolecular Filamentous Assemblies. Biomacromolecules 18 (11) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Xuankuo Xu