Yih-Chih Chan

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 17

Top Topics

Metastatic Colorectal Cancer

Squamous Cell Carcinoma

Chronic Lymphocytic Leukemia

Top Venues

Nature cell biology

Nature communications

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Andrew A Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic, Wesley P Blackaby, David Hardick, Yih-Chih Chan, Ali Motazedian, Andrea Gillespie, Dane Vassiliadis, Enid Y N Lam, Kevin Tran, Byron Andrews, Michael E Harbour, Lina Vasiliauskaite, Claire J Saunders, Georgia Tsagkogeorga, Aleksandra Azevedo, Joanna Obacz, Ewa S Pilka, Marie Carkill, Laura MacPherson, Elanor N Wainwright, Brian J Liddicoat, Benjamin J Blyth, Mark R Albertella, Oliver Rausch, Mark A Dawson
Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances anti-tumour immunity. Cancer discovery (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson
CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia. Nature structural & molecular biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Michael Y He, Michael M Halford, Ruofei Liu, James P Roy, Zoe L Grant, Leigh Coultas, Niko Thio, Omer Gilan, Yih-Chih Chan, Mark A Dawson, Marc G Achen, Steven A Stacker
Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy. Communications biology 4 (1) (2021)
Katie A Fennell, Dane Vassiliadis, Enid Y N Lam, Luciano G Martelotto, Jesse J Balic, Sebastian Hollizeck, Tom S Weber, Timothy Semple, Qing Wang, Denise C Miles, Laura MacPherson, Yih-Chih Chan, Andrew A Guirguis, Lev M Kats, Emily S Wong, Sarah-Jane Dawson, Shalin H Naik, Mark A Dawson
Non-genetic determinants of malignant clonal fitness at single-cell resolution. Nature (2021)
Ashley P Ng, Hannah D Coughlan, Soroor Hediyeh-Zadeh, Kira Behrens, Timothy M Johanson, Michael Sze Yuan Low, Charles C Bell, Omer Gilan, Yih-Chih Chan, Andrew J Kueh, Thomas Boudier, Rebecca Feltham, Anna Gabrielyan, Ladina DiRago, Craig D Hyland, Helen Ierino, Sandra Mifsud, Elizabeth Viney, Tracy Willson, Mark A Dawson, Rhys S Allan, Marco J Herold, Kelly Rogers, David Mathew Tarlinton, Aaron T L Lun, Melissa J Davis, Stephen L Nutt, Warren S Alexander
An Erg-driven transcriptional program controls B cell lymphopoiesis. Nature communications 11 (1) (2020)
Charles C Bell, Katie A Fennell, Yih-Chih Chan, Florian Rambow, Miriam M Yeung, Dane Vassiliadis, Luis Lara, Paul Yeh, Luciano G Martelotto, Aljosja Rogiers, Brandon E Kremer, Olena Barbash, Helai P Mohammad, Timothy M Johanson, Marian L Burr, Arindam Dhar, Natalie Karpinich, Lu-Yi Tian, Dean S Tyler, Laura MacPherson, Junwei Shi, Nathan Pinnawala, Chun Yew Fong, Anthony T Papenfuss, Sean M Grimmond, Sarah-Jane Dawson, Rhys S Allan, Ryan G Kruger, Christopher R Vakoc, David L Goode, Shalin H Naik, Omer Gilan, Enid Y N Lam, Jean-Christophe Marine, Rabinder K Prinjha, Mark A Dawson
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia. Nature communications 10 (1) (2019)
Rishu Agarwal, Yih-Chih Chan, Constantine S Tam, Tane Hunter, Dane Vassiliadis, Charis E Teh, Rachel Thijssen, Paul Yeh, Stephen Q Wong, Sarah Ftouni, Enid Y N Lam, Mary Ann Anderson, Christiane Pott, Omer Gilan, Charles C Bell, Kathy Knezevic, Piers Blombery, Kathleen Rayeroux, Adrian Zordan, Jason Li, David C S Huang, Meaghan Wall, John F Seymour, Daniel H D Gray, Andrew W Roberts, Mark A Dawson, Sarah-Jane Dawson
Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma. Nature medicine 25 (1) (2018)
Dean S Tyler, Johanna Vappiani, Tatiana Cañeque, Enid Y N Lam, Aoife Ward, Omer Gilan, Yih-Chih Chan, Antje Hienzsch, Anna Rutkowska-Klute, Thilo Werner, Anne J Wagner, Dave Lugo, Richard Gregory, Cesar Ramirez Molina, Neil Garton, Christopher R Wellaway, Susan Jackson, Laura MacPherson, Margarida Figueiredo, Sabine Stolzenburg, Charles C Bell, Colin House, Sarah-Jane Dawson, Edwin D Hawkins, Gerard Drewes, Rabinder K Prinjha, Raphaël Rodriguez, Paola Grandi, Mark A Dawson
Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science (New York, N.Y.) 356 (6345) (2017)