Aaron T L Lun (G K Smyth, Gordon K Smyth)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 79

Top Venues

Nature communications

Nature immunology

Genome research

Nature cell biology

Walter and Eliza Hall Institute of Medical Research

Australian National University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Walter and Eliza Hall Institute of Medical Research Sep 01 2014

Australia

Division Head :: Bioinformatics

Walter and Eliza Hall Institute of Medical Research Jan 01 2007 - Aug 31 2014

Australia

Laboratory Head :: Bioinformatics Division

Education History

Australian National University Mar 01 1980 - Sep 05 1985

Australia

PHD :: Statistics, Institute of Advanced Studies

Publications

Sophia Y Y Mah, Hannah K Vanyai, Connie S N Li-Wai-Suen, Alexandra L Garnham, Jessica Wynn, Maria I Bergamasco, Shezlie Malelang, Stephen Wilcox, Christine Biben, Aaron T L Lun, Tim Thomas, Anne Kathrin Voss
ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development. Development (Cambridge, England) 151 (5) (2024)
Tellier J, Ilariya Tarasova, Junli Nie, Christopher S Smillie, Pasquale L Fedele, Wang H J Cao, Joanna R Groom, Gabrielle T Belz, Deepta Bhattacharya, Aaron T L Lun, Stephen L Nutt
Unraveling the diversity and functions of tissue-resident plasma cells. Nature immunology 25 (2) (2024)
Christine R Keenan, Hannah D Coughlan, Nadia Iannarella, Andres Tapia Del Fierro, Andrew Keniry, Timothy M Johanson, Wing Fuk Chan, Alexandra L Garnham, Lachlan W Whitehead, Marnie E Blewitt, Aaron T L Lun, Rhys S Allan
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription. Genome research 34 (4) (2024)
Elizabeth Lieschke, Annabella F Thomas, Andrew Kueh, Georgia K Atkin-Smith, Pedro L Baldoni, John E La Marca, Savannah Young, Allan Shuai Huang, Aisling M Ross, Lauren Whelan, Deeksha Kaloni, Lin Tai, Aaron T L Lun, Marco J Herold, Edwin D Hawkins, Andreas Strasser, Gemma L Kelly
Mouse models to investigate in situ cell fate decisions induced by p53. The EMBO journal (2024)
Winnie Tan, Jeong Veen Park, Hariprasad Venugopal, Jie Qiong Lou, Prabavi Shayana Dias, Pedro L Baldoni, Toby Dite, Kyoung-Wook Moon, Christine R Keenan, Alexandra D Gurzau, Andrew Leis, Jumana Yousef, Vineet Vaibhav, Laura F Dagley, Ching-Seng Ang, Laura Corso, Chen Davidovich, Stephin J Vervoort, Aaron T L Lun, Marnie E Blewitt, Rhys S Allan, Elizabeth Hinde, Sheena D'Arcy, Je-Kyung Ryu, Shabih Shakeel
MORC2 phosphorylation fine tunes its DNA compaction activity. bioRxiv : the preprint server for biology (2024)
Rachel Joyce, Rosa Pascual, Luuk Heitink, Bianca D Capaldo, François Vaillant, Michael Christie, Minhsuang Tsai, Elliot Surgenor, Casey J A Anttila, Pradeep Rajasekhar, Felicity C Jackling, Marie Trussart, Michael J G Milevskiy, Xiaoyu Song, Mengbo Li, Charis E Teh, Daniel H D Gray, null null, Aaron T L Lun, Yunshun Chen, Geoffrey J Lindeman, Jane E Visvader
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers. Nature cell biology 26 (1) (2024)
Christine R Keenan, Hannah D Coughlan, Nadia Iannarella, Andres Tapia Del Fierro, Andrew Keniry, Timothy M Johanson, Wing Fuk Chan, Alexandra L Garnham, Lachlan W Whitehead, Marnie E Blewitt, Aaron T L Lun, Rhys S Allan
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription. Genome research 34 (4) (2024)
Tellier J, Ilariya Tarasova, Junli Nie, Christopher S Smillie, Pasquale L Fedele, Wang H J Cao, Joanna R Groom, Gabrielle T Belz, Deepta Bhattacharya, Aaron T L Lun, Stephen L Nutt
Unraveling the diversity and functions of tissue-resident plasma cells. Nature immunology 25 (2) (2024)
Rachel Joyce, Rosa Pascual, Luuk Heitink, Bianca D Capaldo, François Vaillant, Michael Christie, Minhsuang Tsai, Elliot Surgenor, Casey J A Anttila, Pradeep Rajasekhar, Felicity C Jackling, Marie Trussart, Michael J G Milevskiy, Xiaoyu Song, Mengbo Li, Charis E Teh, Daniel H D Gray, null null, Aaron T L Lun, Yunshun Chen, Geoffrey J Lindeman, Jane E Visvader
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers. Nature cell biology (2024)
Christine R Keenan, Hannah D Coughlan, Nadia Iannarella, Andres Tapia Del Fierro, Andrew Keniry, Timothy M Johanson, Wing Fuk Chan, Alexandra L Garnham, Lachlan W Whitehead, Marnie E Blewitt, Aaron T L Lun, Rhys S Allan
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription. Genome research 34 (4) (2024)
Christine R Keenan, Hannah D Coughlan, Nadia Iannarella, Andres Tapia Del Fierro, Andrew Keniry, Timothy M Johanson, Wing Fuk Chan, Alexandra L Garnham, Lachlan W Whitehead, Marnie E Blewitt, Aaron T L Lun, Rhys S Allan
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription. Genome research (2024)
Christine R Keenan, Hannah D Coughlan, Nadia Iannarella, Andres Tapia Del Fierro, Andrew Keniry, Timothy M Johanson, Wing Fuk Chan, Alexandra L Garnham, Lachlan W Whitehead, Marnie E Blewitt, Aaron T L Lun, Rhys S Allan
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription. Genome research 34 (4) (2024)
Christine R Keenan, Hannah D Coughlan, Nadia Iannarella, Andres Tapia Del Fierro, Andrew Keniry, Timothy M Johanson, Wing Fuk Chan, Alexandra L Garnham, Lachlan W Whitehead, Marnie E Blewitt, Aaron T L Lun, Rhys S Allan
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription. Genome research 34 (4) (2024)
Tellier J, Ilariya Tarasova, Junli Nie, Christopher S Smillie, Pasquale L Fedele, Wang H J Cao, Joanna R Groom, Gabrielle T Belz, Deepta Bhattacharya, Aaron T L Lun, Stephen L Nutt
Unraveling the diversity and functions of tissue-resident plasma cells. Nature immunology 25 (2) (2024)
Rachel Joyce, Rosa Pascual, Luuk Heitink, Bianca D Capaldo, François Vaillant, Michael Christie, Minhsuang Tsai, Elliot Surgenor, Casey J A Anttila, Pradeep Rajasekhar, Felicity C Jackling, Marie Trussart, Michael J G Milevskiy, Xiaoyu Song, Mengbo Li, Charis E Teh, Daniel H D Gray, null null, Aaron T L Lun, Yunshun Chen, Geoffrey J Lindeman, Jane E Visvader
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers. Nature cell biology 26 (1) (2024)
Rachel Joyce, Rosa Pascual, Luuk Heitink, Bianca D Capaldo, François Vaillant, Michael Christie, Minhsuang Tsai, Elliot Surgenor, Casey J A Anttila, Pradeep Rajasekhar, Felicity C Jackling, Marie Trussart, Michael J G Milevskiy, Xiaoyu Song, Mengbo Li, Charis E Teh, Daniel H D Gray, null null, Aaron T L Lun, Yunshun Chen, Geoffrey J Lindeman, Jane E Visvader
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers. Nature cell biology 26 (1) (2024)
Tellier J, Ilariya Tarasova, Junli Nie, Christopher S Smillie, Pasquale L Fedele, Wang H J Cao, Joanna R Groom, Gabrielle T Belz, Deepta Bhattacharya, Aaron T L Lun, Stephen L Nutt
Unraveling the diversity and functions of tissue-resident plasma cells. Nature immunology (2024)
Sophia Y Y Mah, Hannah K Vanyai, Connie S N Li-Wai-Suen, Alexandra L Garnham, Jessica Wynn, Maria I Bergamasco, Shezlie Malelang, Stephen Wilcox, Christine Biben, Aaron T L Lun, Tim Thomas, Anne Kathrin Voss
ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development. Development (Cambridge, England) 151 (5) (2024)
Tellier J, Ilariya Tarasova, Junli Nie, Christopher S Smillie, Pasquale L Fedele, Wang H J Cao, Joanna R Groom, Gabrielle T Belz, Deepta Bhattacharya, Aaron T L Lun, Stephen L Nutt
Unraveling the diversity and functions of tissue-resident plasma cells. Nature immunology 25 (2) (2024)
Hesham D Abdulla, Raed F Alserihi, Christoffer Flensburg, Waruni Abeysekera, Meng-Xiao Luo, Daniel H D Gray, Aaron T L Lun, Warren S Alexander, Ian J Majewski, Matthew P McCormack
Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition. The Journal of experimental medicine 220 (6) (2023)
Xueyi Dong, Mei R M Du, Quentin A Gouil, Luyi Tian, Jafar S Jabbari, Rory Bowden, Pedro L Baldoni, Yunshun Chen, Aaron T L Lun, Shanika L Amarasinghe, Charity W Law, Matthew E Ritchie
Benchmarking long-read RNA-sequencing analysis tools using in silico mixtures. Nature methods (2023)
Hesham D Abdulla, Raed F Alserihi, Christoffer Flensburg, Waruni Abeysekera, Meng-Xiao Luo, Daniel H D Gray, Aaron T L Lun, Warren S Alexander, Ian J Majewski, Matthew P McCormack
Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition. The Journal of experimental medicine 220 (6) (2023)
Pedro L Baldoni, Yunshun Chen, Soroor Hediyeh-Zadeh, Yang Liao, Xueyi Dong, Matthew E Ritchie, Wei Shi, Aaron T L Lun
Dividing out quantification uncertainty allows efficient assessment of differential transcript expression with edgeR. Nucleic acids research (2023)
Jinming Cheng, Aaron T L Lun, Yunshun Chen
Unraveling the timeline of gene expression: A pseudotemporal trajectory analysis of single-cell RNA sequencing data. F1000Research 12 (2023)
Hesham D Abdulla, Raed F Alserihi, Christoffer Flensburg, Waruni Abeysekera, Meng-Xiao Luo, Daniel H D Gray, Aaron T L Lun, Warren S Alexander, Ian J Majewski, Matthew P McCormack
Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition. The Journal of experimental medicine 220 (6) (2023)
Hesham D Abdulla, Raed F Alserihi, Christoffer Flensburg, Waruni Abeysekera, Meng-Xiao Luo, Daniel H D Gray, Aaron T L Lun, Warren S Alexander, Ian J Majewski, Matthew P McCormack
Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition. The Journal of experimental medicine 220 (6) (2023)
Melanie Heinlein, Luke C Gandolfo, Kelin Zhao, Charis E Teh, Nghi Nguyen, Jonathan B Baell, Yael Goldfarb, Jakub Abramson, Johannes Wichmann, Anne K Voss, Andreas Strasser, Aaron T L Lun, Tim Thomas, Daniel H D Gray
The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance. Science immunology 7 (67) (2022)
Stephanie I Studniberg, Lisa J Ioannidis, Retno A S Utami, Leily Trianty, Yang Liao, Waruni Abeysekera, Connie Li Wai Suen, Halina M Pietrzak, Julie Healer, Agatha M Puspitasari, Dwi Apriyanti, Farah N Coutrier, Jeanne Rini Poespoprodjo, Enny Kenangalem, Benediktus Andries, Pak Prayoga, Novita Sariyanti, Aaron T L Lun, Alan F Cowman, Richard N Price, Rintis Noviyanti, Wei Shi, Alexandra L Garnham, Diana S Hansen
Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria. Molecular systems biology 18 (4) (2022)
Johannes Wichmann, Catherine Pitt, Samantha Eccles, Alexandra L Garnham, Connie Li Wai Suen, Rose May, Elizabeth Allan, Stephen Wilcox, Marco J Herold, Aaron T L Lun, Brendon J Monahan, Tim Thomas, Anne Kathrin Voss
Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest. Cell death & disease 13 (7) (2022)
Wing Fuk Chan, Hannah D Coughlan, Yunshun Chen, Christine R Keenan, Aaron T L Lun, Andrew Charles Perkins, Timothy M Johanson, Rhys S Allan
Activation of stably silenced genes by recruitment of a synthetic de-methylating module. Nature communications 13 (1) (2022)
Yunshun Chen, Bhupinder Pal, Geoffrey J Lindeman, Jane E Visvader, Aaron T L Lun
R code and downstream analysis objects for the scRNA-seq atlas of normal and tumorigenic human breast tissue. Scientific data 9 (1) (2022)
Farrah El-Saafin, Maria I Bergamasco, Yunshun Chen, Rose E May, Prabagaran Esakky, Soroor Hediyeh-Zadeh, Mathew Dixon, Stephen Wilcox, Melissa J Davis, Andreas Strasser, Aaron T L Lun, Tim Thomas, Anne Kathrin Voss
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell death and differentiation 29 (5) (2022)
Sheng-Bo Zhang, Hannah D Coughlan, Mitra Ashayeripanah, Simona Seizova, Andrew J Kueh, Daniel V Brown, Wang H J Cao, Jacquelot N, Angela D'Amico, Andrew M Lew, Yifan Zhan, Christopher J Tonkin, Jose A Villadangos, Aaron T L Lun, Michaël Chopin, Stephen L Nutt
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT. Science immunology 6 (58) (2022)
Luuk Heitink, James R Whittle, François Vaillant, Bianca D Capaldo, Johanna F Dekkers, Caleb A Dawson, Michael J G Milevskiy, Elliot Surgenor, Minhsuang Tsai, Huei-Rong Chen, Michael Christie, Yunshun Chen, Aaron T L Lun, Marco J Herold, Andreas Strasser, Geoffrey J Lindeman, Jane E Visvader
In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis. Molecular oncology 16 (5) (2022)
Bhupinder Pal, Yunshun Chen, François Vaillant, Bianca D Capaldo, Rachel Joyce, Xiaoyu Song, Vanessa L Bryant, Jocelyn S Penington, Leon Di Stefano, Nina Tubau Ribera, Stephen Wilcox, Gregory B Mann, null null, Anthony T Papenfuss, Geoffrey J Lindeman, Aaron T L Lun, Jane E Visvader
A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast. The EMBO journal 40 (11) (2021)
Zoe L Grant, Peter F Hickey, Waruni Abeysekera, Lachlan W Whitehead, Sabrina M Lewis, Robert C Andrew Symons, Tracey M Baldwin, Daniela Amann-Zalcenstein, Alexandra L Garnham, Aaron T L Lun, Tim Thomas, Anne Kathrin Voss, Leigh Coultas
The histone acetyltransferase HBO1 promotes efficient tip cell sprouting during angiogenesis. Development (Cambridge, England) 148 (20) (2021)
Andrew D Foers, Alexandra L Garnham, Simon Chatfield, Aaron T L Lun, Lesley Cheng, Andrew F Hill, Ian P Wicks, Ken C Pang
Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation. International journal of molecular sciences 22 (9) (2021)
Wing Fuk Chan, Hannah D Coughlan, Jie H S Zhou, Christine R Keenan, Naiara G Bediaga, Philip D Hodgkin, Aaron T L Lun, Timothy M Johanson, Rhys S Allan
Pre-mitotic genome re-organisation bookends the B cell differentiation process. Nature communications 12 (1) (2021)
Yuqing Yang, Andrew J Kueh, Zoe L Grant, Waruni Abeysekera, Alexandra L Garnham, Stephen Wilcox, Craig D Hyland, Ladina Di Rago, Donald Metcalf, Warren S Alexander, Leigh Coultas, Aaron T L Lun, Anne Kathrin Voss, Tim Thomas
The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal. Blood (2021)
Yifan Zhan, Yuxia Zhang, Sheng-Bo Zhang, Hannah D Coughlan, Pedro L Baldoni, Jacquelot N, Wang H J Cao, Simon P Preston, Cynthia Louis, Jai Rautela, Marc Pellegrini, Ian P Wicks, Warren S Alexander, Leonard C Harrison, Andrew M Lew, Aaron T L Lun, Stephen L Nutt, Michaël Chopin
Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis. Science immunology 6 (63) (2021)
Dimitra Zotos, Isaak Quast, Connie Li Wai Suen, Craig I McKenzie, Marcus James Robinson, Andrey Kan, Aaron T L Lun, Philip D Hodgkin, David Mathew Tarlinton
The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21. Nature communications 12 (1) (2021)
Raymond K H Yip, Joel S Rimes, Bianca D Capaldo, François Vaillant, Kellie A Mouchemore, Bhupinder Pal, Yunshun Chen, Elliot Surgenor, Andrew J Murphy, Robin L Anderson, Aaron T L Lun, Geoffrey J Lindeman, Edwin D Hawkins, Jane E Visvader
Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis. Nature communications 12 (1) (2021)
Ashley P Ng, Hannah D Coughlan, Soroor Hediyeh-Zadeh, Kira Behrens, Timothy M Johanson, Michael Sze Yuan Low, Charles C Bell, Omer Gilan, Yih-Chih Chan, Andrew J Kueh, Thomas Boudier, Rebecca Feltham, Anna Gabrielyan, Ladina DiRago, Craig D Hyland, Helen Ierino, Sandra Mifsud, Elizabeth Viney, Tracy Willson, Mark A Dawson, Rhys S Allan, Marco J Herold, Kelly Rogers, David Mathew Tarlinton, Aaron T L Lun, Melissa J Davis, Stephen L Nutt, Warren S Alexander
An Erg-driven transcriptional program controls B cell lymphopoiesis. Nature communications 11 (1) (2020)
James R Whittle, François Vaillant, Elliot Surgenor, Antonia N Policheni, Göknur Giner, Bianca D Capaldo, Huei-Rong Chen, He K Liu, Johanna F Dekkers, Norman Sachs, Hans Clevers, Andrew Fellowes, Thomas Green, Huiling Xu, Stephen B Fox, Marco J Herold, Aaron T L Lun, Daniel H D Gray, Jane E Visvader, Geoffrey J Lindeman
Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (15) (2020)
Najoua Lalaoui, Delphine Merino, Goknur Giner, François Vaillant, Diep Chau, Lin Liu, Tobias Kratina, Bhupinder Pal, James R Whittle, Nima Etemadi, Jean Berthelet, Julius Gräsel, Cathrine Hall, Matthew E Ritchie, Matthias Ernst, Aaron T L Lun, David L Vaux, Jane E Visvader, Geoffrey J Lindeman, John Silke
Targeting triple-negative breast cancers with the Smac-mimetic birinapant. Cell death and differentiation 27 (10) (2020)
Caleb A Dawson, Bhupinder Pal, François Vaillant, Luke C Gandolfo, Zhaoyuan Liu, Camille Bleriot, Florent Ginhoux, Aaron T L Lun, Geoffrey J Lindeman, Scott N Mueller, Anne C Rios, Jane E Visvader
Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling. Nature cell biology 22 (5) (2020)
Andrew D Foers, Alexandra L Garnham, Aaron T L Lun, Susanna M Proudman, Lesley Cheng, Andrew F Hill, Ken C Pang, Ian P Wicks
Circulating Small Noncoding RNA Biomarkers of Response to Triple Disease-modifying Antirheumatic Drug Therapy in White Women With Early Rheumatoid Arthritis. The Journal of rheumatology 47 (12) (2020)
Tom Sidwell, Yang Liao, Alexandra L Garnham, Ajithkumar Vasanthakumar, Renee Gloury, Jonas Blume, Peggy P Teh, David Chisanga, Christoph Thelemann, Fabian de Labastida Rivera, Christian R Engwerda, Lynn Corcoran, Kohei Kometani, Tomohiro Kurosaki, Aaron T L Lun, Wei Shi, Axel Kallies
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis. Nature communications 11 (1) (2020)
Charity W Law, Kathleen Zeglinski, Xueyi Dong, Monther Alhamdoosh, Aaron T L Lun, Matthew E Ritchie
A guide to creating design matrices for gene expression experiments. F1000Research 9 (2020)
Angus T Stock, Nicholas Collins, Aaron T L Lun, Yifang Hu, Jacinta A Hansen, Damian B D'Silva, Hamdi A Jama, Andrew M Lew, Thomas Gebhardt, Catriona A McLean, Ian P Wicks
The Selective Expansion and Targeted Accumulation of Bone Marrow-Derived Macrophages Drive Cardiac Vasculitis. Journal of immunology (Baltimore, Md. : 1950) 202 (11) (2019)
Christina Vrahnas, Martha Blank, Toby A Dite, Liliana Tatarczuch, Niloufar Ansari, Blessing Crimeen-Irwin, Huynh Nguyen, Mark R Forwood, Yifang Hu, Mika Iikegame, Keith R Bambery, Cyril Petibois, Eleanor Jean Mackie, Mark J Tobin, Aaron T L Lun, Jonathan S Oakhill, T John Martin, Natalie A Sims
Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone. Nature communications 10 (1) (2019)
Delphine Merino, Tom S Weber, A Serrano, François Vaillant, K Liu, Bhupinder Pal, Leon Di Stefano, Jaring Schreuder, Dawn S Lin, Yunshun Chen, Marie-Liesse Asselin-Labat, Ton N M Schumacher, Daniel L Cameron, Aaron T L Lun, Anthony T Papenfuss, Geoffrey J Lindeman, Jane E Visvader, Shalin H Naik
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer. Nature communications 10 (1) (2019)
Christina Vrahnas, Martha Blank, Toby A Dite, Liliana Tatarczuch, Niloufar Ansari, Blessing Crimeen-Irwin, Huynh Nguyen, Mark R Forwood, Yifang Hu, Mika Iikegame, Keith R Bambery, Cyril Petibois, Eleanor Jean Mackie, Mark J Tobin, Aaron T L Lun, Jonathan S Oakhill, T John Martin, Natalie A Sims
Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone. Nature communications 10 (1) (2019)
Cyril Seillet, Kylie Luong, Julie Tellier, Nicolas Jacquelot, Rui Dong Shen, Peter F Hickey, Verena C Wimmer, Lachlan Whitehead, Kelly Rogers, Aaron T L Lun, Alexandra L Garnham, Matthew E Ritchie, Gabrielle T Belz
The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity. Nature immunology 21 (2) (2019)
Necla Koçhan, G Yazgi Tutuncu, Aaron T L Lun, Luke C Gandolfo, Göknur Giner
qtQDA: quantile transformed quadratic discriminant analysis for high-dimensional RNA-seq data. PeerJ 7 (2019)
Delphine Merino, Tom S Weber, A Serrano, François Vaillant, K Liu, Bhupinder Pal, Leon Di Stefano, Jaring Schreuder, Dawn S Lin, Yunshun Chen, Marie-Liesse Asselin-Labat, Ton N M Schumacher, Daniel L Cameron, Aaron T L Lun, Anthony T Papenfuss, Geoffrey J Lindeman, Jane E Visvader, Shalin H Naik
Publisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer. Nature communications 10 (1) (2019)
Hannah K Vanyai, Alexandra Garnham, Rose E May, Helen M McRae, Caitlin Collin, Stephen Wilcox, Aaron T L Lun, Tim Thomas, Anne Kathrin Voss
MOZ directs the distal-less homeobox gene expression program during craniofacial development. Development (Cambridge, England) 146 (14) (2019)
Helen M McRae, Alexandra L Garnham, Yifang Hu, Matthew T Witkowski, Mark A Corbett, Mathew P Dixon, Rose E May, Bilal N Sheikh, William Chiang, Andrew J Kueh, Tan A Nguyen, Kevin Man, Renee Gloury, Brandon J Aubrey, Antonia Policheni, Ladina Di Rago, Warren S Alexander, Daniel H D Gray, Andreas Strasser, Edwin D Hawkins, Stephen Wilcox, Jozef Gecz, Axel Kallies, Matthew P McCormack, Aaron T L Lun, Anne K Voss, Tim Thomas
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia. Blood 133 (16) (2019)
Wen C Aw, Samuel G Towarnicki, Richard G Melvin, Neil A Youngson, Michael R Garvin, Yifang Hu, Shaun Nielsen, Torsten Thomas, Russell Pickford, Sonia Bustamante, Antón Vila-Sanjurjo, Aaron T L Lun, J William O Ballard
Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness. PLoS genetics 14 (11) (2018)
Sheau W Lok, James R Whittle, François Vaillant, Charis E Teh, Louisa L Lo, Antonia N Policheni, Alice R T Bergin, Jayesh Desai, Sarah Ftouni, Luke C Gandolfo, Danny Liew, He K Liu, G Bruce Mann, Kate Moodie, Anand Murugasu, Bhupinder Pal, Andrew W Roberts, Mark A Rosenthal, Kylie Shackleton, Maria João Silva, Zhen R Siow, Aaron T L Lun, Leanne Taylor, Avraham Travers, Belinda Yeo, Miriam M Yeung, Andjelija Zivanovic Bujak, Sarah-Jane Dawson, Daniel H D Gray, Jane E Visvader, Geoffrey J Lindeman
A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2-Positive Metastatic Breast Cancer. Cancer discovery 9 (3) (2018)
Timothy M Johanson, Aaron T L Lun, Hannah D Coughlan, Tania Tan, Aaron T L Lun, Stephen L Nutt, Rhys S Allan
Transcription-factor-mediated supervision of global genome architecture maintains B cell identity. Nature immunology 19 (11) (2018)
Timothy M Johanson, Hannah D Coughlan, Aaron T L Lun, Naiara G Bediaga, Gaetano Naselli, Alexandra L Garnham, Leonard C Harrison, Aaron T L Lun, Rhys S Allan
Genome-wide analysis reveals no evidence of trans chromosomal regulation of mammalian immune development. PLoS genetics 14 (6) (2018)
Delphine Merino, James R Whittle, François Vaillant, Antonin Serrano, Goknur Giner, Ana Leticia Maragno, Maïa Chanrion, Emilie Schneider, Bhupinder Pal, Xiang Li, Grant Dewson, Julius Gräsel, Kevin Liu, Najoua Lalaoui, David Segal, Marco J Herold, David Ching Siang Huang, Aaron T L Lun, Olivier Geneste, Guillaume L Lessene, Jane E Visvader, Geoffrey J Lindeman
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer. Science translational medicine 9 (401) (2018)
Aaron T L Lun, Aaron T L Lun
No counts, no variance: allowing for loss of degrees of freedom when assessing biological variability from RNA-seq data. Statistical applications in genetics and molecular biology 16 (2) (2018)
Steven P Williams, Adam F Odell, Tara Karnezis, Rae H Farnsworth, Cathryn M Gould, Jason Li, Sophie Paquet-Fifield, Nicole C Harris, Anne Walter, Julia L Gregory, Sara F Lamont, Ruofei Liu, Elena A Takano, Cameron J Nowell, Neil I Bower, Daniel Resnick, Aaron T L Lun, Leigh Coultas, Benjamin M Hogan, Stephen B Fox, Scott N Mueller, Kaylene J Simpson, Marc G Achen, Steven A Stacker
Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling. Science signaling 10 (499) (2017)
Nai Yang Fu, Anne C Rios, Bhupinder Pal, Charity W Law, Paul Jamieson, Ruijie Liu, François Vaillant, Felicity Jackling, Kevin He Liu, Aaron T L Lun, Geoffrey J Lindeman, Matthew E Ritchie, Jane E Visvader
Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive. Nature cell biology 19 (3) (2017)
Nima Etemadi, Michael Chopin, Holly Anderton, Maria C Tanzer, James A Rickard, Waruni Abeysekera, Cathrine Hall, Sukhdeep K Spall, Bing Wang, Yuquan Xiong, Timothy Hla, Stuart M Pitson, Claudine S Bonder, Wendy Wei-Lynn Wong, Matthias Ernst, Aaron T L Lun, David L Vaux, Stephen L Nutt, Ueli Nachbur, John Silke
Correction: TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. eLife 6 (2017)
Bhupinder Pal, Yunshun Chen, François Vaillant, Paul Jamieson, Lavinia Gordon, Anne C Rios, Stephen Wilcox, Naiyang Fu, Kevin He Liu, Felicity C Jackling, Melissa J Davis, Geoffrey J Lindeman, Aaron T L Lun, Jane E Visvader
Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling. Nature communications 8 (1) (2017)
Yunshun Chen, Bhupinder Pal, Jane E Visvader, Aaron T L Lun
Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR. F1000Research (2017)
Yunshun Chen, Bhupinder Pal, Jane E Visvader, Aaron T L Lun
Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR. F1000Research 6 (2017)
Matthew T Witkowski, Yifang Hu, Kathryn G Roberts, Judith M Boer, Mark D McKenzie, Grace J Liu, Oliver D Le Grice, Cedric S Tremblay, Margherita Ghisi, Tracy A Willson, Martin A Horstmann, Iannis Aifantis, Luisa Cimmino, Seth Frietze, Monique L Den Boer, Charles G Mullighan, Aaron T L Lun, Ross A Dickins
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome. The Journal of experimental medicine 214 (3) (2017)
Julie Tellier, Wei Shi, Martina Minnich, Yang Liao, Simon Crawford, Aaron T L Lun, Axel Kallies, Meinrad Busslinger, Stephen L Nutt
Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response. Nature immunology 17 (3) (2016)
Charis E Teh, Najoua Lalaoui, Reema Jain, Antonia N Policheni, Melanie Heinlein, Silvia Alvarez-Diaz, Julie M Sheridan, Eva Rieser, Stefanie Deuser, Maurice Darding, Hui-Fern Koay, Yifang Hu, Fiona Kupresanin, Lorraine A O'Reilly, Dale I Godfrey, Aaron T L Lun, Philippe Bouillet, Andreas Strasser, Henning Walczak, John Silke, Daniel H D Gray
Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis. Nature communications 7 (2016)
Charity W Law, Monther Alhamdoosh, Shian Su, Xueyi Dong, Lu-Yi Tian, Aaron T L Lun, Matthew E Ritchie
RNA-seq analysis is easy as 1-2-3 with limma, Glimma and edgeR. F1000Research 5 (2016)
Annie Xin, Frederick Masson, Yang Liao, Simon Preston, Tianxia Guan, Renee Gloury, Moshe Olshansky, Jian-Xin Lin, Peng Li, Terence P Speed, Aaron T L Lun, Matthias Ernst, Warren J Leonard, Marc Pellegrini, Susan M Kaech, Stephen L Nutt, Wei Shi, Gabrielle T Belz, Axel Kallies
A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nature immunology 17 (4) (2016)
Emma Nolan, François Vaillant, Daniel Branstetter, Bhupinder Pal, Göknur Giner, Lachlan W Whitehead, Sheau W Lok, Gregory B Mann, null null, Kathy Rohrbach, Li-Ya Huang, Rosalia Soriano, Aaron T L Lun, William C Dougall, Jane E Visvader, Geoffrey J Lindeman
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers. Nature medicine 22 (8) (2016)
Michael J Coffey, Robin B Gasser, Alessandro D Uboldi, Alexandra Garnham, Magdalena Franco, Nicole D Marino, Michael W Panas, David J P Ferguson, Marta Enciso, Matthew T O'Neill, Sash Lopaticki, Rebecca J Stewart, Grant Dewson, Aaron T L Lun, Brian J Smith, Seth L Masters, John C Boothroyd, Justin A Boddey, Christopher J Tonkin
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell. eLife 4 (2015)
Lucille C Rankin, Mathilde J H Girard-Madoux, Cyril Seillet, Lisa A Mielke, Yann Kerdiles, Aurore Fenis, Elisabeth Wieduwild, Tracy Putoczki, Stanislas Mondot, Olivier Lantz, Dieter Demon, Anthony T Papenfuss, Aaron T L Lun, Mohamed Lamkanfi, Sebastian Carotta, Jean-Christophe Renauld, Wei Shi, Sabrina Carpentier, Tim Soos, Christopher Arendt, Sophie Ugolini, Nicholas D Huntington, Gabrielle T Belz, Eric Vivier
Complementarity and redundancy of IL-22-producing innate lymphoid cells. Nature immunology 17 (2) (2015)
Nima Etemadi, Michael Chopin, Holly Anderton, Maria C Tanzer, James A Rickard, Waruni Abeysekera, Cathrine Hall, Sukhdeep K Spall, Bing Wang, Yuquan Xiong, Timothy Hla, Stuart M Pitson, Claudine S Bonder, Wendy Wei-Lynn Wong, Matthias Ernst, Aaron T L Lun, David L Vaux, Stephen L Nutt, Ueli Nachbur, John Silke
TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. eLife 4 (2015)

Aaron T L Lun.css-eqlu8i{font-size:small;padding-left:4px;} (G K Smyth, Gordon K Smyth)

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Aaron T L Lun (G K Smyth, Gordon K Smyth)