Enid Y N Lam (Enid Yn Lam)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 19

Top Topics

Top Venues

Nature cell biology

Nature genetics

Science (New York, N.Y.)

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Charles C Bell, Jesse J Balic, Laure Talarmain, Andrea Gillespie, Laura Scolamiero, Enid Y N Lam, Ching-Seng Ang, Geoffrey J Faulkner, Omer Gilan, Mark A Dawson
Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription. Nature genetics 56 (6) (2024)
Charles C Bell, Jesse J Balic, Laure Talarmain, Andrea Gillespie, Laura Scolamiero, Enid Y N Lam, Ching-Seng Ang, Geoffrey J Faulkner, Omer Gilan, Mark A Dawson
Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription. Nature genetics (2024)
Charles C Bell, Jesse J Balic, Laure Talarmain, Andrea Gillespie, Laura Scolamiero, Enid Y N Lam, Ching-Seng Ang, Geoffrey J Faulkner, Omer Gilan, Mark A Dawson
Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription. Nature genetics 56 (6) (2024)
Andrew A Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic, Wesley P Blackaby, David Hardick, Yih-Chih Chan, Ali Motazedian, Andrea Gillespie, Dane Vassiliadis, Enid Y N Lam, Kevin Tran, Byron Andrews, Michael E Harbour, Lina Vasiliauskaite, Claire J Saunders, Georgia Tsagkogeorga, Aleksandra Azevedo, Joanna Obacz, Ewa S Pilka, Marie Carkill, Laura MacPherson, Elanor N Wainwright, Brian J Liddicoat, Benjamin J Blyth, Mark R Albertella, Oliver Rausch, Mark A Dawson
Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances anti-tumour immunity. Cancer discovery (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson
CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia. Nature structural & molecular biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Zlata Vershinin, Michal Feldman, Thilo Werner, Lital Estrella Weil, Margarita Kublanovsky, Elina Abaev-Schneiderman, Menachem Sklarz, Enid Y N Lam, Khawla Alasad, Sarah Picaud, Barak Rotblat, Ruth A McAdam, Vered Chalifa-Caspi, Marcus Bantscheff, Trevor Chapman, Huw D Lewis, Panagis Filippakopoulos, Mark A Dawson, Paola Grandi, Rabinder K Prinjha, Dan Levy
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Science advances 7 (22) (2021)
Katie A Fennell, Dane Vassiliadis, Enid Y N Lam, Luciano G Martelotto, Jesse J Balic, Sebastian Hollizeck, Tom S Weber, Timothy Semple, Qing Wang, Denise C Miles, Laura MacPherson, Yih-Chih Chan, Andrew A Guirguis, Lev M Kats, Emily S Wong, Sarah-Jane Dawson, Shalin H Naik, Mark A Dawson
Non-genetic determinants of malignant clonal fitness at single-cell resolution. Nature (2021)
Omer Gilan, Inmaculada Rioja, Kathy Knezevic, Matthew J Bell, Miriam M Yeung, Nicola R Harker, Enid Y N Lam, Chun-Wa Chung, Paul Bamborough, Massimo Petretich, Marjeta Urh, Stephen J Atkinson, Anna K Bassil, Emma J Roberts, Dane Vassiliadis, Marian L Burr, Alex G S Preston, Christopher R Wellaway, Thilo Werner, James R Gray, Anne-Marie Michon, Thomas Gobbetti, Vinod Kumar, Peter E Soden, Andrea Haynes, Johanna Vappiani, David F Tough, Simon J Taylor, Sarah-Jane Dawson, Marcus Bantscheff, Matthew Lindon, Gerard Drewes, Emmanuel H Demont, Danette L Daniels, Paola Grandi, Rabinder K Prinjha, Mark A Dawson
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science (New York, N.Y.) 368 (6489) (2020)
Charles C Bell, Katie A Fennell, Yih-Chih Chan, Florian Rambow, Miriam M Yeung, Dane Vassiliadis, Luis Lara, Paul Yeh, Luciano G Martelotto, Aljosja Rogiers, Brandon E Kremer, Olena Barbash, Helai P Mohammad, Timothy M Johanson, Marian L Burr, Arindam Dhar, Natalie Karpinich, Lu-Yi Tian, Dean S Tyler, Laura MacPherson, Junwei Shi, Nathan Pinnawala, Chun Yew Fong, Anthony T Papenfuss, Sean M Grimmond, Sarah-Jane Dawson, Rhys S Allan, Ryan G Kruger, Christopher R Vakoc, David L Goode, Shalin H Naik, Omer Gilan, Enid Y N Lam, Jean-Christophe Marine, Rabinder K Prinjha, Mark A Dawson
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia. Nature communications 10 (1) (2019)
Dean S Tyler, Johanna Vappiani, Tatiana Cañeque, Enid Y N Lam, Aoife Ward, Omer Gilan, Yih-Chih Chan, Antje Hienzsch, Anna Rutkowska-Klute, Thilo Werner, Anne J Wagner, Dave Lugo, Richard Gregory, Cesar Ramirez Molina, Neil Garton, Christopher R Wellaway, Susan Jackson, Laura MacPherson, Margarida Figueiredo, Sabine Stolzenburg, Charles C Bell, Colin House, Sarah-Jane Dawson, Edwin D Hawkins, Gerard Drewes, Rabinder K Prinjha, Raphaël Rodriguez, Paola Grandi, Mark A Dawson
Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science (New York, N.Y.) 356 (6345) (2017)