Yun Chen

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 23

Top Topics

Neuropathic Pain

Age Related Macular Degeneration

Endothelial Cells

Top Venues

The Journal of experimental medicine

Science translational medicine

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Jin-Chao Hou, Yun Chen, Zhangying Cai, Gyu Seong Heo, Carla M Yuede, Zuoxu Wang, Kent Lin, Fareeha Saadi, Tihana Trsan, Aivi T Nguyen, Eleni Constantopoulos, Rachel A Larsen, Yiyang Zhu, Nicole D Wagner, Nolan McLaughlin, Xinyi Cynthia Kuang, Alexander D Barrow, Dian Li, Yingyue Zhou, Shoutang Wang, Susan Gilfillan, Michael L Gross, Simone Brioschi, Yongjian Liu, David M Holtzman, Marco Colonna
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model. Science translational medicine 16 (741) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Jin-Chao Hou, Yun Chen, Zhangying Cai, Gyu Seong Heo, Carla M Yuede, Zuoxu Wang, Kent Lin, Fareeha Saadi, Tihana Trsan, Aivi T Nguyen, Eleni Constantopoulos, Rachel A Larsen, Yiyang Zhu, Nicole D Wagner, Nolan McLaughlin, Xinyi Cynthia Kuang, Alexander D Barrow, Dian Li, Yingyue Zhou, Shoutang Wang, Susan Gilfillan, Michael L Gross, Simone Brioschi, Yongjian Liu, David M Holtzman, Marco Colonna
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model. Science translational medicine 16 (741) (2024)
Jin-Chao Hou, Yun Chen, Zhangying Cai, Gyu Seong Heo, Carla M Yuede, Zuoxu Wang, Kent Lin, Fareeha Saadi, Tihana Trsan, Aivi T Nguyen, Eleni Constantopoulos, Rachel A Larsen, Yiyang Zhu, Nicole D Wagner, Nolan McLaughlin, Xinyi Cynthia Kuang, Alexander D Barrow, Dian Li, Yingyue Zhou, Shoutang Wang, Susan Gilfillan, Michael L Gross, Simone Brioschi, Yongjian Liu, David M Holtzman, Marco Colonna
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model. Science translational medicine 16 (741) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Jin-Chao Hou, Yun Chen, Zhangying Cai, Gyu Seong Heo, Carla M Yuede, Zuoxu Wang, Kent Lin, Fareeha Saadi, Tihana Trsan, Aivi T Nguyen, Eleni Constantopoulos, Rachel A Larsen, Yiyang Zhu, Nicole D Wagner, Nolan McLaughlin, Xinyi Cynthia Kuang, Alexander D Barrow, Dian Li, Yingyue Zhou, Shoutang Wang, Susan Gilfillan, Michael L Gross, Simone Brioschi, Yongjian Liu, David M Holtzman, Marco Colonna
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model. Science translational medicine 16 (741) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jin-Chao Hou, Kai Schlepckow, Simone Degan, Lindsey A Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D Proia, Marco Colonna, Christian Haass, Daniel R Saban
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. The Journal of experimental medicine 221 (3) (2024)
Rui Sun, Rowland H Han, Colin McCornack, Saad M Khan, G Travis Tabor, Yun Chen, Jinchao Hou, Haowu Jiang, Kathleen M Schoch, Diane D Mao, Ryan Cleary, Alicia Yang, Qin Liu, Jingqin R Luo, Allegra A Petti, Timothy M Miller, Jason D Ulrich, David M Holtzman, Albert H Kim
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma. Science advances 9 (19) (2023)
Rui Sun, Rowland H Han, Colin McCornack, Saad M Khan, G Travis Tabor, Yun Chen, Jinchao Hou, Haowu Jiang, Kathleen M Schoch, Diane D Mao, Ryan Cleary, Alicia Yang, Qin Liu, Jingqin R Luo, Allegra A Petti, Timothy M Miller, Jason D Ulrich, David M Holtzman, Albert H Kim
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma. Science advances 9 (19) (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Rui Sun, Rowland H Han, Colin McCornack, Saad M Khan, G Travis Tabor, Yun Chen, Jinchao Hou, Haowu Jiang, Kathleen M Schoch, Diane D Mao, Ryan Cleary, Alicia Yang, Qin Liu, Jingqin R Luo, Allegra A Petti, Timothy M Miller, Jason D Ulrich, David M Holtzman, Albert H Kim
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma. Science advances 9 (19) (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Rui Sun, Rowland H Han, Colin McCornack, Saad M Khan, G Travis Tabor, Yun Chen, Jinchao Hou, Haowu Jiang, Kathleen M Schoch, Diane D Mao, Ryan Cleary, Alicia Yang, Qin Liu, Jingqin R Luo, Allegra A Petti, Timothy M Miller, Jason D Ulrich, David M Holtzman, Albert H Kim
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma. Science advances 9 (19) (2023)
Maud Gratuze, Yun Chen, Samira Parhizkar, Nimansha Jain, Michael R Strickland, Javier Remolina Serrano, Marco Colonna, Jason D Ulrich, David M Holtzman
Activated microglia mitigate Aβ-associated tau seeding and spreading. The Journal of experimental medicine 218 (8) (2021)
Yun Chen, Marco Colonna
Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice? The Journal of experimental medicine 218 (9) (2021)