James A J Fitzpatrick (James Fitzpatrick)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 40

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Science translational medicine

Science (New York, N.Y.)

Washington University in Saint Louis

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University in Saint Louis Jan 06 2015

United States

Professor :: Neuroscience

Salk Institute for Biological Studies Dec 15 2009 - May 01 2015

United States

Core Director :: Biophotonics

Publications

Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Deborah A Berthold, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Richard J Perrin, Joel S Perlmutter, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Nature communications 15 (1) (2024)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Deborah A Berthold, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Richard J Perrin, Joel S Perlmutter, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Nature communications 15 (1) (2024)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Deborah A Berthold, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Richard J Perrin, Joel S Perlmutter, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Nature communications 15 (1) (2024)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Deborah A Berthold, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Richard J Perrin, Joel S Perlmutter, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Nature communications 15 (1) (2024)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Deborah A Berthold, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Richard J Perrin, Joel S Perlmutter, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Nature communications 15 (1) (2024)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. bioRxiv : the preprint server for biology (2023)
Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Samuel Achilefu, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain. Nature communications 14 (1) (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Samuel Achilefu, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain. Nature communications 14 (1) (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. bioRxiv : the preprint server for biology (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Jaigeeth Deveryshetty, Rahul Chadda, Jenna Mattice, Simrithaa Karunakaran, Michael J Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A J Fitzpatrick, Brian Bothner, Edwin Antony
C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination. bioRxiv : the preprint server for biology (2023)
Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Samuel Achilefu, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain. Nature communications 14 (1) (2023)
Jaigeeth Deveryshetty, Rahul Chadda, Jenna R Mattice, Simrithaa Karunakaran, Michael J Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A J Fitzpatrick, Brian Bothner, Edwin Antony
Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes. Nature communications 14 (1) (2023)
Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Samuel Achilefu, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain. Nature communications 14 (1) (2023)
Roshan Sivakumar, Katherine Floyd, Erath Jessey, Jenny Kim Kim, Peter O Bayguinov, James A J Fitzpatrick, Dennis Goldfrab, Marko Jovanovic, Abhai K Tripathi, Sergej Djuranovic, Slavica Pavlovic-Djuranovic
Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum . bioRxiv : the preprint server for biology (2023)
Jaigeeth Deveryshetty, Rahul Chadda, Jenna Mattice, Simrithaa Karunakaran, Michael J Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A J Fitzpatrick, Brian Bothner, Edwin Antony
C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination. bioRxiv : the preprint server for biology (2023)
Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Samuel Achilefu, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain. Nature communications 14 (1) (2023)
Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Samuel Achilefu, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain. Nature communications 14 (1) (2023)
Dhruva D Dhavale, Alexander M Barclay, Collin G Borcik, Katherine Basore, Isabelle R Gordon, Jialu Liu, Moses H Milchberg, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Soumyo Sen, Brock Summers, John Smith, Owen A Warmuth, Qian Chen, James A J Fitzpatrick, Charles D Schwieters, Emad Tajkhorshid, Chad M Rienstra, Paul T Kotzbauer
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. bioRxiv : the preprint server for biology (2023)
Jaigeeth Deveryshetty, Rahul Chadda, Jenna Mattice, Simrithaa Karunakaran, Michael J Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A J Fitzpatrick, Brian Bothner, Edwin Antony
C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination. bioRxiv : the preprint server for biology (2023)
Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert W Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric C Landsness, James A J Fitzpatrick, Michael Wong, Robert R Townsend, Marco Colonna, Robert E Schmidt, David M Holtzman
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice. Science translational medicine 15 (693) (2023)
Cliff J Luke, Stephanie Markovina, Misty Good, Ira E Wight, Brian J Thomas, John M Linneman, Wyatt E Lanik, Olga Koroleva, Maggie R Coffman, Mark T Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, Liyun Chen, Wandy L Beatty, Kelsey N Hausmann, Frances V White, James A J Fitzpatrick, Anthony Orvedahl, Stephen C Pak, Gary A Silverman
Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins. Communications biology 5 (1) (2022)
Eliza A Ruben, Brock Summers, Michael J Rau, James A J Fitzpatrick, Enrico Di Cera
Cryo-EM structure of the prothrombin-prothrombinase complex. Blood 139 (24) (2022)
John T Petroff, Noah M Dietzen, Ezry Santiago-McRae, Brett Deng, Maya S Washington, Lawrence J Chen, K Trent Moreland, Zengqin Deng, Michael J Rau, James A J Fitzpatrick, Peng Yuan, Thomas T Joseph, Jérôme Hénin, Grace Brannigan, Wayland W L Cheng
Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nature communications 13 (1) (2022)
Jonathan W Mount, Grigory Maksaev, Brock T Summers, James A J Fitzpatrick, Peng Yuan
Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel. Nature communications 13 (1) (2022)
Ankan K Bhadra, Michael J Rau, Jil A Daw, James A J Fitzpatrick, Conrad C Weihl, Heather L True
Disease-associated mutations within the yeast DNAJB6 homolog Sis1 slow conformer-specific substrate processing and can be corrected by the modulation of nucleotide exchange factors. Nature communications 13 (1) (2022)
Jing Feng, Yonghui Zhao, Zili Xie, Kaikai Zang, Sanja Sviben, Xue-Ming Hu, James A J Fitzpatrick, Lu Wen, Yifei Liu, Ting Wang, Katy Lawson, Qin Liu, Yan Yan, Xinzhong Dong, Liang Han, Gregory F Wu, Brian S Kim, Hongzhen Hu
Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle. Science translational medicine 14 (653) (2022)
Deanna L Mendez, Ethan P Lowder, Dustin E Tillman, Molly C Sutherland, Andrea L Collier, Michael J Rau, James A J Fitzpatrick, Robert G Kranz
Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport. Nature chemical biology 18 (1) (2021)
Eliza A Ruben, Michael J Rau, James A J Fitzpatrick, Enrico Di Cera
Cryo-EM structures of human coagulation factors V and Va. Blood 137 (22) (2021)
Krishan K Pandey, Sibes Bera, Ke Shi, Michael J Rau, Amarachi V Oleru, James A J Fitzpatrick, Alan N Engelman, Hideki Aihara, Duane P Grandgenett
Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Communications biology 4 (1) (2021)
Simone Brioschi, Wei-Le Wang, Vincent Peng, Meng Wang, Irina Shchukina, Zev J Greenberg, Jennifer K Bando, Natalia Jaeger, Rafael S Czepielewski, Amanda Swain, Denis A Mogilenko, Wandy L Beatty, Peter Bayguinov, James A J Fitzpatrick, Laura G Schuettpelz, Catrina C Fronick, Igor Smirnov, Jonathan Kipnis, Virginia Smith Shapiro, Gregory F Wu, Susan Gilfillan, Marina Cella, Maxim N Artyomov, Steven H Kleinstein, Marco Colonna
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders. Science (New York, N.Y.) 373 (6553) (2021)
Naveen C Reddy, Shahriyar P Majidi, Lingchun Kong, Mati Nemera, Cole J Ferguson, Michael Moore, Tassia M Goncalves, Hai-Kun Liu, James A J Fitzpatrick, Guoyan Zhao, Tomoko Yamada, Azad Bonni, Harrison W Gabel
CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nature communications 12 (1) (2021)
Zengqin Deng, Yonghui Zhao, Jing Feng, Jingying Zhang, Haiyan Zhao, Michael J Rau, James A J Fitzpatrick, Hongzhen Hu, Peng Yuan
Cryo-EM structure of a proton-activated chloride channel TMEM206. Science advances 7 (9) (2021)
Zengqin Deng, Grigory Maksaev, Michael J Rau, Zili Xie, Hongzhen Hu, James A J Fitzpatrick, Peng Yuan
Gating of human TRPV3 in a lipid bilayer. Nature structural & molecular biology 27 (7) (2020)
Zengqin Deng, Grigory Maksaev, Angela M Schlegel, Jingying Zhang, Michael J Rau, James A J Fitzpatrick, Elizabeth S Haswell, Peng Yuan
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance. Nature communications 11 (1) (2020)
Zengqin Deng, Zhihui He, Grigory Maksaev, Ryan M Bitter, Michael J Rau, James A J Fitzpatrick, Peng Yuan
Cryo-EM structures of the ATP release channel pannexin 1. Nature structural & molecular biology 27 (4) (2020)
Ruben Hervas, Michael J Rau, Younshim Park, Wenjuan Zhang, Alexey G Murzin, James A J Fitzpatrick, Sjors H W Scheres, Kausik Si
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila. Science (New York, N.Y.) 367 (6483) (2020)
Kyunghee X Kim, Shelby Payne, Aizhen Yang-Hood, Song-Zhe Li, Bethany Davis, Jason Carlquist, Babak V-Ghaffari, Jay A Gantz, Dorina Kallogjeri, James A J Fitzpatrick, Kevin K Ohlemiller, Keiko Hirose, Mark A Rutherford
Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (23) (2019)

James A J Fitzpatrick.css-eqlu8i{font-size:small;padding-left:4px;} (James Fitzpatrick)

Publication Activity (10 Years)

Top Topics

Top Venues

James A J Fitzpatrick (James Fitzpatrick)