Yvonne Y Chen

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Venues

The Journal of experimental medicine

Nature metabolism

Neuro-oncology

Nature chemical biology

University of California, Los Angeles

California Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California, Los Angeles

United States

Associate Professor :: Microbiology, Immunology, and Molecular Genetics

Education History

California Institute of Technology

United States

PHD :: Chemical Engineering

Stanford University

United States

BSC :: Chemical Engineering

Publications

Melanie Ayala Ceja, Mobina Khericha, Caitlin M Harris, Cristina Puig-Saus, Yvonne Y Chen
CAR-T cell manufacturing: Major process parameters and next-generation strategies. The Journal of experimental medicine 221 (2) (2024)
Aliya Lakhani, Ximin Chen, Laurence C Chen, Mihe Hong, Mobina Khericha, Yu Chen, Yvonne Y Chen, Junyoung O Park
Extracellular domains of CARs reprogramme T cell metabolism without antigen stimulation. Nature metabolism (2024)
Melanie Ayala Ceja, Mobina Khericha, Caitlin M Harris, Cristina Puig-Saus, Yvonne Y Chen
CAR-T cell manufacturing: Major process parameters and next-generation strategies. The Journal of experimental medicine 221 (2) (2024)
Andrew J Hou, Ryan M Shih, Benjamin R Uy, Amanda Shafer, Ze Nan L Chang, Begonya Comin-Anduix, Miriam Guemes, Zoran Galic, Su Phyu, Hideho Okada, Katie B Grausam, Joshua J Breunig, Christine E Brown, David A Nathanson, Robert M Prins, Yvonne Y Chen
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma. Neuro-oncology (2024)
Meng-Yin Lin, Eunwoo Nam, Ryan M Shih, Amanda Shafer, Amber Bouren, Melanie Ayala Ceja, Caitlin M Harris, Mobina Khericha, Kenny H Vo, Minsoo Kim, Chi-Hong Tseng, Yvonne Y Chen
Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy. The Journal of experimental medicine 221 (6) (2024)
Aliya Lakhani, Ximin Chen, Laurence C Chen, Mihe Hong, Mobina Khericha, Yu Chen, Yvonne Y Chen, Junyoung O Park
Extracellular domains of CARs reprogramme T cell metabolism without antigen stimulation. Nature metabolism (2024)
Aliya Lakhani, Ximin Chen, Laurence C Chen, Mihe Hong, Mobina Khericha, Yu Chen, Yvonne Y Chen, Junyoung O Park
Extracellular domains of CARs reprogramme T cell metabolism without antigen stimulation. Nature metabolism 6 (6) (2024)
Meng-Yin Lin, Eunwoo Nam, Ryan M Shih, Amanda Shafer, Amber Bouren, Melanie Ayala Ceja, Caitlin M Harris, Mobina Khericha, Kenny H Vo, Minsoo Kim, Chi-Hong Tseng, Yvonne Y Chen
Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy. The Journal of experimental medicine 221 (6) (2024)
Meng-Yin Lin, Eunwoo Nam, Ryan M Shih, Amanda Shafer, Amber Bouren, Melanie Ayala Ceja, Caitlin M Harris, Mobina Khericha, Kenny H Vo, Minsoo Kim, Chi-Hong Tseng, Yvonne Y Chen
Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy. The Journal of experimental medicine 221 (6) (2024)
Meng-Yin Lin, Eunwoo Nam, Ryan M Shih, Amanda Shafer, Amber Bouren, Melanie Ayala Ceja, Caitlin M Harris, Mobina Khericha, Kenny H Vo, Minsoo Kim, Chi-Hong Tseng, Yvonne Y Chen
Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy. The Journal of experimental medicine 221 (6) (2024)
Melanie Ayala Ceja, Mobina Khericha, Caitlin M Harris, Cristina Puig-Saus, Yvonne Y Chen
CAR-T cell manufacturing: Major process parameters and next-generation strategies. The Journal of experimental medicine 221 (2) (2024)
Aliya Lakhani, Ximin Chen, Laurence C Chen, Mihe Hong, Mobina Khericha, Yu Chen, Yvonne Y Chen, Junyoung O Park
Extracellular domains of CARs reprogramme T cell metabolism without antigen stimulation. Nature metabolism (2024)
Andrew J Hou, Ryan M Shih, Benjamin R Uy, Amanda Shafer, Ze Nan L Chang, Begonya Comin-Anduix, Miriam Guemes, Zoran Galic, Su Phyu, Hideho Okada, Katie B Grausam, Joshua J Breunig, Christine E Brown, David A Nathanson, Robert M Prins, Yvonne Y Chen
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma. Neuro-oncology (2024)
Aliya Lakhani, Ximin Chen, Laurence C Chen, Mihe Hong, Mobina Khericha, Yu Chen, Yvonne Y Chen, Junyoung O Park
Extracellular domains of CARs reprogramme T cell metabolism without antigen stimulation. Nature metabolism 6 (6) (2024)
Aliya Lakhani, Ximin Chen, Laurence C Chen, Mobina Khericha, Yvonne Y Chen, Junyoung O Park
Extracellular Domains of CAR Reprogram T-Cell Metabolism Without Antigen Stimulation. bioRxiv : the preprint server for biology (2023)
Ximin Chen, Laurence C Chen, Mobina Khericha Gandhi, Xiangzhi Meng, Emma Salvestrini, Amanda Shafer, Neha Iyer, Anya S Alag, Yunfeng Ding, Demetri M Nicolaou, Yvonne Y Chen
Rational protein design yields a CD20 CAR with superior antitumor efficacy compared to CD19 CAR. Cancer immunology research (2022)
Sarah M Larson, Christopher M Walthers, Brenda Ji, Sanaz N Ghafouri, Jacob Naparstek, Jacqueline Trent, Jia Ming Chen, Mobina Roshandell, Caitlin M Harris, Mobina Khericha, Thomas Schweppe, Beata Berent-Maoz, Stanley B Gosliner, Amr Almaktari, Melanie Ayala Ceja, Martin S Allen-Auerbach, Jonathan W Said, Karla Nawaly, Monica Mead, Sven de Vos, Patricia A Young, Caspian Oliai, Gary J Schiller, John M Timmerman, Antoni Ribas, Yvonne Y Chen
CD19/CD20 Bispecific Chimeric Antigen Receptor (CAR) in Naïve/Memory T Cells for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma. Cancer discovery (2022)
Justin D Clubb, Torahito A Gao, Yvonne Y Chen
Synthetic Biology in the Engineering of CAR-T and CAR-NK Cell Therapies: Facts and Hopes. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Andrew J Hou, Laurence C Chen, Yvonne Y Chen
Navigating CAR-T cells through the solid-tumour microenvironment. Nature reviews. Drug discovery 20 (7) (2021)
Yvonne Y Chen
Cell fishing with DNA aptamers. Nature biomedical engineering 3 (10) (2020)
Eugenia Zah, Eunwoo Nam, Vinya Bhuvan, Uyen Tran, Brenda Y Ji, Stanley B Gosliner, Xiuli Wang, Christine E Brown, Yvonne Y Chen
Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma. Nature communications 11 (1) (2020)
ZeNan Li Chang, Andrew J Hou, Yvonne Y Chen
Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands. Nature protocols 15 (4) (2020)
ZeNan Li Chang, Michael H Lorenzini, Ximin Chen, Uyen Tran, Nathanael J Bangayan, Yvonne Y Chen
Rewiring T-cell responses to soluble factors with chimeric antigen receptors. Nature chemical biology 14 (3) (2018)
Andrew J Hou, ZeNan L Chang, Michael H Lorenzini, Eugenia Zah, Yvonne Y Chen
TGF-β-responsive CAR-T cells promote anti-tumor immune function. Bioengineering & translational medicine 3 (2) (2018)
Patrick Ho, Christopher Ede, Yvonne Y Chen
Modularly Constructed Synthetic Granzyme B Molecule Enables Interrogation of Intracellular Proteases for Targeted Cytotoxicity. ACS synthetic biology 6 (8) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Yvonne Y Chen