Zhanjun Hou

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 29

Top Topics

Molecular Docking

Endoplasmic Reticulum

Top Venues

Molecular cancer therapeutics

Cancer research communications

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Jade M Katinas, Md Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N Fifer, Lily M Klapper, Abhishekh Sharma, Kishore Thalluri, Michael S Van Nieuwenhze, Zhanjun Hou, Aleem Gangjee, Larry H Matherly, Charles E Dann
Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry (2024)
Hussein Chehade, Radhika P Gogoi, Nicholas K Adzibolosu, Sandra Galoforo, Rouba-Ali Fehmi, Mira Kheil, Alexandra Lucienne Fox, Seongho Kim, Ramandeep Rattan, Zhanjun Hou, Robert T Morris, Larry H Matherly, Gil Mor, Ayesha B Alvero
BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer. Cancer research communications 4 (8) (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and cytosolic one-carbon metabolism is a targetable metabolic vulnerability in cisplatin-resistant ovarian cancer. Molecular cancer therapeutics (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer. Molecular cancer therapeutics 23 (6) (2024)
Hussein Chehade, Radhika P Gogoi, Nicholas K Adzibolosu, Sandra Galoforo, Rouba-Ali Fehmi, Mira Kheil, Alexandra Lucienne Fox, Seongho Kim, Ramandeep Rattan, Zhanjun Hou, Robert T Morris, Larry H Matherly, Gil Mor, Ayesha B Alvero
BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer. Cancer research communications 4 (8) (2024)
Hussein Chehade, Radhika P Gogoi, Nicholas K Adzibolosu, Sandra Galoforo, Rouba-Ali Fehmi, Mira Kheil, Alexandra Lucienne Fox, Seongho Kim, Ramandeep Rattan, Zhanjun Hou, Robert T Morris, Larry H Matherly, Gil Mor, Ayesha B Alvero
BRCA status dictates Wnt responsiveness in epithelial ovarian cancer. Cancer research communications (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer. Molecular cancer therapeutics 23 (6) (2024)
Jade M Katinas, Md Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N Fifer, Lily M Klapper, Abhishekh Sharma, Kishore Thalluri, Michael S Van Nieuwenhze, Zhanjun Hou, Aleem Gangjee, Larry H Matherly, Charles E Dann
Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry (2024)
Carrie O'Connor, Mathew Schneider, Jade M Katinas, Md Junayed Nayeen, Khushbu Shah, Tejashree Magdum, Abhishekh Sharma, Seongho Kim, Xun Bao, Jing Li, Charles E Dann, Aleem Gangjee, Larry H Matherly, Zhanjun Hou
Role of mitochondrial and cytosolic folylpolyglutamate synthetase in one-carbon metabolism and antitumor efficacy of mitochondrial-targeted antifolates . Molecular pharmacology (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer. Molecular cancer therapeutics 23 (6) (2024)
Jade M Katinas, Md Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N Fifer, Lily M Klapper, Abhishekh Sharma, Kishore Thalluri, Michael S Van Nieuwenhze, Zhanjun Hou, Aleem Gangjee, Larry H Matherly, Charles E Dann
Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry (2024)
Jade M Katinas, Md Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N Fifer, Lily M Klapper, Abhishekh Sharma, Kishore Thalluri, Michael S Van Nieuwenhze, Zhanjun Hou, Aleem Gangjee, Larry H Matherly, Charles E Dann
Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry (2024)
Jade M Katinas, Md Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N Fifer, Lily M Klapper, Abhishekh Sharma, Kishore Thalluri, Michael S Van Nieuwenhze, Zhanjun Hou, Aleem Gangjee, Larry H Matherly, Charles E Dann
Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer. Molecular cancer therapeutics 23 (6) (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and cytosolic one-carbon metabolism is a targetable metabolic vulnerability in cisplatin-resistant ovarian cancer. Molecular cancer therapeutics (2024)
Jade M Katinas, Md Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N Fifer, Lily M Klapper, Abhishekh Sharma, Kishore Thalluri, Michael S Van Nieuwenhze, Zhanjun Hou, Aleem Gangjee, Larry H Matherly, Charles E Dann
Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer. Molecular cancer therapeutics 23 (6) (2024)
Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne, Xun Bao, Md Junayed Nayeen, Mathew Schneider, Jade M Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B Back, Charles E Dann, Aleem Gangjee, Zhanjun Hou, Larry H Matherly
Mitochondrial and cytosolic one-carbon metabolism is a targetable metabolic vulnerability in cisplatin-resistant ovarian cancer. Molecular cancer therapeutics (2024)
Hussein Chehade, Radhika P Gogoi, Nicholas K Adzibolosu, Sandra Galoforo, Rouba-Ali Fehmi, Mira Kheil, Alexandra Lucienne Fox, Seongho Kim, Ramandeep Rattan, Zhanjun Hou, Robert T Morris, Larry H Matherly, Gil Mor, Ayesha B Alvero
BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer. Cancer research communications 4 (8) (2024)
Krishna Kaku, Manasa P Ravindra, Nian Tong, Shruti Choudhary, Xinxin Li, Jianming Yu, Mohammad Karim, Madelyn Brzezinski, Carrie O'Connor, Zhanjun Hou, Larry H Matherly, Aleem Gangjee
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC Transport. ACS medicinal chemistry letters 14 (12) (2023)
Krishna Kaku, Manasa P Ravindra, Nian Tong, Shruti Choudhary, Xinxin Li, Jianming Yu, Mohammad Karim, Madelyn Brzezinski, Carrie O'Connor, Zhanjun Hou, Larry H Matherly, Aleem Gangjee
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC Transport. ACS medicinal chemistry letters 14 (12) (2023)
Md Junayed Nayeen, Jade M Katinas, Tejashree Magdum, Khushbu Shah, Jennifer E Wong, Carrie E O'Connor, Alexandra N Fifer, Adrianne Wallace-Povirk, Zhanjun Hou, Larry H Matherly, Charles E Dann, Aleem Gangjee
Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria. Journal of medicinal chemistry (2023)
Krishna Kaku, Manasa P Ravindra, Nian Tong, Shruti Choudhary, Xinxin Li, Jianming Yu, Mohammad Karim, Madelyn Brzezinski, Carrie O'Connor, Zhanjun Hou, Larry H Matherly, Aleem Gangjee
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC Transport. ACS medicinal chemistry letters 14 (12) (2023)
Larry H Matherly, Zhanjun Hou
Folate transporter offers clues for anticancer drugs. Nature 612 (7938) (2022)
Jordan B Burton, Nicholas J Carruthers, Zhanjun Hou, Larry H Matherly, Paul M Stemmer
Pattern Analysis of Organellar Maps for Interpretation of Proteomic Data. Proteomes 10 (2) (2022)
Zhanjun Hou, Aleem Gangjee, Larry H Matherly
The evolving biology of the proton-coupled folate transporter: New insights into regulation, structure, and mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36 (2) (2022)
Aamod S Dekhne, Zhanjun Hou, Aleem Gangjee, Larry H Matherly
Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in Cancer. Molecular cancer therapeutics 19 (11) (2020)
Zhanjun Hou, Carrie O'Connor, Josephine Frühauf, Steve Orr, Seongho Kim, Aleem Gangjee, Larry H Matherly
Regulation of differential proton-coupled folate transporter gene expression in human tumors: transactivation by KLF15 with NRF-1 and the role of Sp1. The Biochemical journal 476 (8) (2019)
Aamod S Dekhne, Khushbu Shah, Gregory S Ducker, Jade M Katinas, Jennifer Wong-Roushar, Md Junayed Nayeen, Arpit Doshi, Changwen Ning, Xun Bao, Josephine Frühauf, Jenney Liu, Adrianne Wallace-Povirk, Carrie O'Connor, Sijana H Dzinic, Kathryn White, Juiwanna Kushner, Seongho Kim, Maik Hüttemann, Lisa Polin, Joshua D Rabinowitz, Jing Li, Zhanjun Hou, Charles E Dann, Aleem Gangjee, Larry H Matherly
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Molecular cancer therapeutics 18 (10) (2019)