Zhe Han

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Venues

Disease models & mechanisms

bioRxiv : the preprint server for biology

Cells

Cell & bioscience

University of Maryland Baltimore

University of Michigan (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Maryland Baltimore Jun 24 2019

United States

Associate Professor :: Medicine

Children's National Health System - Jun 23 2019

United States

Associate Professor :: Genetic Medicine

University of Michigan

United States

Assistant Professor :: Medicine

Education History

University of Michigan

United States

PHD :: Molecular, Cellular and Developmental Biology

Peking University

China

BSC :: Genetics

Publications

Jun-Yi Zhu, Joyce van de Leemput, Zhe Han
Promoting mitochondrial dynamics by inhibiting the PINK1-PRKN pathway to relieve diabetic nephropathy. Disease models & mechanisms 17 (4) (2024)
Jun-Yi Zhu, Joyce van de Leemput, Zhe Han
Promoting mitochondrial dynamics by inhibiting the PINK1-PRKN pathway to relieve diabetic nephropathy. Disease models & mechanisms 17 (4) (2024)
Jianli Duan, Pei Wen, Yunpo Zhao, Joyce van de Leemput, Jennifer Lai Yee, Damian Fermin, Bradley A Warady, Susan L Furth, Derek K Ng, Matthew Gordon Sampson, Zhe Han
A Drosophila model to screen Alport syndrome COL4A5 variants for their functional pathogenicity. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Joyce van de Leemput, Zhe Han
Promoting mitochondrial dynamics by inhibiting the PINK1-PRKN pathway to relieve diabetic nephropathy. Disease models & mechanisms 17 (4) (2024)
Joyce van de Leemput, Zhe Han
Drosophila Nephrocyte as a Model for Studying Glomerular Basement Membrane Physiology. Journal of the American Society of Nephrology : JASN (2024)
Jun-Yi Zhu, Yulong Fu, Joyce van de Leemput, Ying Yu, Jinliang Li, Patricio E Ray, Zhe Han
HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Yulong Fu, Joyce van de Leemput, Ying Yu, Jinliang Li, Patricio E Ray, Zhe Han
HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Jianli Duan, Joyce van de Leemput, Zhe Han
Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in Drosophila Nephrocytes. Cells 13 (15) (2024)
Megan Delaney, Yunpo Zhao, Joyce van de Leemput, Hangnoh Lee, Zhe Han
Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in Drosophila Nephrocytes. Cells 13 (16) (2024)
Jun-Yi Zhu, Jianli Duan, Joyce van de Leemput, Zhe Han
Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in Drosophila Nephrocytes. Cells 13 (15) (2024)
Jun-Yi Zhu, Joyce van de Leemput, Zhe Han
Promoting mitochondrial dynamics by inhibiting the PINK1-PRKN pathway to relieve diabetic nephropathy. Disease models & mechanisms 17 (4) (2024)
Jun-Yi Zhu, Yulong Fu, Joyce van de Leemput, Ying Yu, Jinliang Li, Patricio E Ray, Zhe Han
HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Yulong Fu, Joyce van de Leemput, Ying Yu, Jinliang Li, Patricio E Ray, Zhe Han
HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Joyce van de Leemput, Zhe Han
Promoting mitochondrial dynamics by inhibiting the PINK1/PRKN pathway to relieve diabetic nephropathy. Disease models & mechanisms (2024)
Megan Delaney, Yunpo Zhao, Joyce van de Leemput, Hangnoh Lee, Zhe Han
Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in Drosophila Nephrocytes. Cells 13 (16) (2024)
Megan Delaney, Yunpo Zhao, Joyce van de Leemput, Hangnoh Lee, Zhe Han
Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in Drosophila Nephrocytes. Cells 13 (16) (2024)
Jun-Yi Zhu, Yulong Fu, Joyce van de Leemput, Ying Yu, Jinliang Li, Patricio E Ray, Zhe Han
HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Joyce van de Leemput, Zhe Han
Promoting mitochondrial dynamics by inhibiting the PINK1-PRKN pathway to relieve diabetic nephropathy. Disease models & mechanisms 17 (4) (2024)
Jianli Duan, Pei Wen, Yunpo Zhao, Joyce van de Leemput, Jennifer Lai Yee, Damian Fermin, Bradley A Warady, Susan L Furth, Derek K Ng, Matthew Gordon Sampson, Zhe Han
A Drosophila model to screen Alport syndrome COL4A5 variants for their functional pathogenicity. bioRxiv : the preprint server for biology (2024)
Jun-Yi Zhu, Jianli Duan, Joyce van de Leemput, Zhe Han
Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in Drosophila Nephrocytes. Cells 13 (15) (2024)
Xiaohu Huang, Yulong Fu, Hangnoh Lee, Yunpo Zhao, Wendy Yang, Joyce van de Leemput, Zhe Han
Single-cell profiling of the developing embryonic heart in Drosophila. Development (Cambridge, England) (2023)
Jin-Gu Lee, Yulong Fu, Jun-Yi Zhu, Pei Wen, Joyce van de Leemput, Patricio E Ray, Zhe Han
A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes. Cell & bioscience 13 (1) (2023)
Jun-Yi Zhu, Hangnoh Lee, Xiaohu Huang, Joyce van de Leemput, Zhe Han
Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of Drosophila Heart Development. International journal of molecular sciences 24 (24) (2023)
Jun-Yi Zhu, Hangnoh Lee, Xiaohu Huang, Joyce van de Leemput, Zhe Han
Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of Drosophila Heart Development. International journal of molecular sciences 24 (24) (2023)
Jun-Yi Zhu, Hangnoh Lee, Xiaohu Huang, Joyce van de Leemput, Zhe Han
Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of Drosophila Heart Development. International journal of molecular sciences 24 (24) (2023)
Young Wook Chun, Matthew Miyamoto, Charles H Williams, Leif R Neitzel, Maya Silver-Isenstadt, Adrian G Cadar, Daniela T Fuller, Daniel C Fong, Hanhan Liu, Robert Lease, Sungseek Kim, Mikako Katagiri, Matthew D Durbin, Kuo-Chen Wang, Tromondae K Feaster, Calvin C Sheng, M Diana Neely, Urmila Sreenivasan, Marcia Cortes-Gutierrez, Aloke V Finn, Rachel Schot, Grazia M S Mancini, Seth A Ament, Kevin C Ess, Aaron B Bowman, Zhe Han, David P Bichell, Yan Ru Su, Charles C Hong
Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy. Circulation (2023)
Jun-Yi Zhu, Hangnoh Lee, Xiaohu Huang, Joyce van de Leemput, Zhe Han
Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of Drosophila Heart Development. International journal of molecular sciences 24 (24) (2023)
Jun-Yi Zhu, Jin-Gu Lee, Yulong Fu, Joyce van de Leemput, Patricio E Ray, Zhe Han
APOL1-G2 accelerates nephrocyte cell death by inhibiting the autophagy pathway. Disease models & mechanisms (2023)
Seong Kyu Han, Michelle T McNulty, Christopher J Benway, Pei Wen, Anya Greenberg, Ana C Onuchic-Whitford, null null, Dongkeun Jang, Jason Flannick, Noël P Burtt, Parker C Wilson, Benjamin D Humphreys, Xiaoquan Wen, Zhe Han, Dongwon Lee, Matthew Gordon Sampson
Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs. Nature communications 14 (1) (2023)
Jun-Yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A Kane, Peixin Yang, Zhe Han
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis. Communications biology 5 (1) (2022)
Wei-Bin Shen, James Logue, Penghua Yang, Lauren Baracco, Montasir Elahi, E Albert Reece, Bingbing Wang, Ling Li, Thomas G Blanchard, Zhe Han, Matthew B Frieman, Robert A Rissman, Peixin Yang
SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology. bioRxiv : the preprint server for biology (2022)
Jin-Gu Lee, Weiliang Huang, Hangnoh Lee, Joyce van de Leemput, Maureen A Kane, Zhe Han
Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor. Cell & bioscience 11 (1) (2021)
Jun-Yi Zhu, Jin-Gu Lee, Joyce van de Leemput, Hangnoh Lee, Zhe Han
Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment. Cell & bioscience 11 (1) (2021)
Ruofan Yu, Xiaohua Cao, Luyang Sun, Jun-Yi Zhu, Brian M Wasko, Wei Liu, Emeline Crutcher, Haiying Liu, Myeong Chan Jo, Lidong Qin, Matt Kaeberlein, Zhe Han, Weiwei Dang
Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism. Nature communications 12 (1) (2021)
Jun-Yi Zhu, Xiaohu Huang, Yulong Fu, Yin Wang, Pan Zheng, Yang Liu, Zhe Han
Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS-induced cancer phenotypes. Disease models & mechanisms 15 (2) (2021)
Xuesi Wan, James Perry, Haichen Zhang, Feng Jin, Kathleen A Ryan, Cristopher Van Hout, Jeffrey Reid, John Overton, Aris Baras, Zhe Han, Elizabeth Streeten, Yanbing Li, Braxton D Mitchell, Alan R Shuldiner, Mao Fu, null null
Heterozygosity for a Pathogenic Variant in SLC12A3 That Causes Autosomal Recessive Gitelman Syndrome Is Associated with Lower Serum Potassium. Journal of the American Society of Nephrology : JASN 32 (3) (2021)
Joyce van de Leemput, Zhe Han
Drosophila, a powerful model to study virus-host interactions and pathogenicity in the fight against SARS-CoV-2. Cell & bioscience 11 (1) (2021)
Luyao Wang, Pei Wen, Joyce van de Leemput, Zhanzheng Zhao, Zhe Han
Slit diaphragm maintenance requires dynamic clathrin-mediated endocytosis facilitated by AP-2, Lap, Aux and Hsc70-4 in nephrocytes. Cell & bioscience 11 (1) (2021)
Jun-Yi Zhu, Amy Heidersbach, Irfan S Kathiriya, Bayardo I Garay, Kathryn N Ivey, Deepak Srivastava, Zhe Han, Isabelle N King
The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Development (Cambridge, England) 144 (5) (2017)
Jun-Yi Zhu, Yulong Fu, Margaret Nettleton, Adam Richman, Zhe Han
High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila. eLife 6 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Zhe Han