Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines.
Timothy W ClarkJillian MohanMichael R ShortreedKirsten ObernierMohammad Sadnan Al ManirChristopher P ChurasAmir DailamyYesh DoctorAntoine ForgetJan Niklas HansenMengzhou HuJoanna LenkiewiczMaxwell Adam LevinsonCharlotte MarquezSami NourreddineJustin NiestroyDexter PrattGege QianSwathi ThakerJean-Christophe Bélisle-PiponCynthia A BrandtJake ChenYing DingSamah Jamal FodehNevan J KroganEmma LundbergPrashant MaliPamela Payne-FosterSarah Jane RatcliffeVardit RavitskyAndrej SaliWade L SchulzTrey IdekerPublished in: bioRxiv : the preprint server for biology (2024)
This article describes the Cell Maps for Artificial Intelligence (CM4AI) project and its goals, methods, standards, current datasets, software tools, status, and future directions. CM4AI is the Functional Genomics Data Generation Project in the U.S. National Institute of Health's (NIH) Bridge2AI program. Its overarching mission is to produce ethical, AI-ready datasets of cell architecture, inferred from multimodal data collected for human cell lines, to enable transformative biomedical AI research.