Immune Determinants of the Association between Tumor Mutational Burden and Immunotherapy Response across Cancer Types.
Neelam SinhaSanju SinhaCristina ValeroAlejandro A SchäfferKenneth D AldapeKevin LitchfieldTimothy A ChanLuc G T MorrisEytan RuppinPublished in: Cancer research (2022)
This study uncovers immune-related factors that may modulate the relationship between high tumor mutational burden and ICI response, which can help prioritize cancer types for clinical trials.