Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.
Luise LinsenmeierBehnam MohammadiMohsin ShafiqKarl J FrontzekJulia BärAmulya Nidhi ShrivastavaMarkus DammeFeizhi SongAlexander SchwarzStefano Da VelaTania MassignanSebastian JungAngela CorreiaMatthias SchmitzBerta PuigSimone HornemannInga ZerrJörg TatzeltEmiliano BiasiniPaul SaftigMichaela SchweizerDmitri I SvergunLadan AminFederica MazzolaLuca VaraniSimrika ThapaSabine GilchHermann M SchatzlDavid A HarrisAntoine TrillerMarina MikhaylovaAdriano AguzziHermann Clemens AltmeppenMarkus GlatzelPublished in: Science advances (2021)
[Figure: see text].