Simone Hornemann

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Topics

Platelet Rich Plasma

Top Venues

EMBO molecular medicine

Nature structural & molecular biology

This page only lists publications with an associated author ORCID identifier.

Publications

Daniel Heinzer, Merve Avar, Manuela Pfammatter, Rita Moos, Petra Schwarz, Matthias T Buhmann, Benjamin Kuhn, Stefan Mauerhofer, Urs Rosenberg, Adriano Aguzzi, Simone Hornemann
Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as surgical instrument mimetic. PloS one 19 (6) (2024)
Daniel Heinzer, Merve Avar, Manuela Pfammatter, Rita Moos, Petra Schwarz, Matthias T Buhmann, Benjamin Kuhn, Stefan Mauerhofer, Urs Rosenberg, Adriano Aguzzi, Simone Hornemann
Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as surgical instrument mimetic. PloS one 19 (6) (2024)
Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niklas Bargenda, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Petra Schwarz, Mario Nuvolone, Gunilla T Westermark, K Peter R Nilsson, Magdalini Polymenidou, Alexandre Pa Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis. EMBO molecular medicine (2024)
Karl J Frontzek, Marco Bardelli, Assunta Senatore, Anna Henzi, Regina R Reimann, Seden Bedir, Marika Marino, Rohanah Hussain, Simon Jurt, Georg Meisl, Mattia Pedotti, Federica Mazzola, Giuliano Siligardi, Oliver Zerbe, Marco Losa, Tuomas P J Knowles, Asvin Lakkaraju, Caihong Zhu, Petra Schwarz, Simone Hornemann, Matthew G Holt, Luca Simonelli, Luca Varani, Adriano Aguzzi
A conformational switch controlling the toxicity of the prion protein. Nature structural & molecular biology 29 (8) (2022)
Merve Avar, Daniel Heinzer, Alana M Thackray, Yingjun Liu, Marian Hruska-Plochan, Stefano Sellitto, Elke Schaper, Daniel Patrick Pease, Jiang-An Yin, Asvin K K Lakkaraju, Marc Emmenegger, Marco Losa, Andra Chincisan, Simone Hornemann, Magdalini Polymenidou, Raymond Bujdoso, Adriano Aguzzi
An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation. The EMBO journal 41 (23) (2022)
Georg Meisl, Timothy Kurt, Itzel Condado-Morales, Cyrus Bett, Silvia Sorce, Mario Nuvolone, Thomas C T Michaels, Daniel Heinzer, Merve Avar, Samuel I A Cohen, Simone Hornemann, Adriano Aguzzi, Christopher M Dobson, Christina J Sigurdson, Tuomas P J Knowles
Scaling analysis reveals the mechanism and rates of prion replication in vivo. Nature structural & molecular biology 28 (4) (2021)
Luise Linsenmeier, Behnam Mohammadi, Mohsin Shafiq, Karl J Frontzek, Julia Bär, Amulya Nidhi Shrivastava, Markus Damme, Feizhi Song, Alexander Schwarz, Stefano Da Vela, Tania Massignan, Sebastian Jung, Angela Correia, Matthias Schmitz, Berta Puig, Simone Hornemann, Inga Zerr, Jörg Tatzelt, Emiliano Biasini, Paul Saftig, Michaela Schweizer, Dmitri I Svergun, Ladan Amin, Federica Mazzola, Luca Varani, Simrika Thapa, Sabine Gilch, Hermann M Schatzl, David A Harris, Antoine Triller, Marina Mikhaylova, Adriano Aguzzi, Hermann Clemens Altmeppen, Markus Glatzel
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies. Science advances 7 (48) (2021)
Marc Emmenegger, Elena De Cecco, Marian Hruska-Plochan, Timo Eninger, Matthias M Schneider, Melanie Barth, Elena Tantardini, Pierre de Rossi, Mehtap Bacioglu, Rebekah G Langston, Alice Kaganovich, Nora Bengoa-Vergniory, Andrès Gonzalez-Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M Häsler, Therese W Herling, Naunehal S Matharu, Natalie Landeck, Kelvin C Luk, Ronald Melki, Philipp J Kahle, Simone Hornemann, Tuomas P J Knowles, Mark R Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies. EMBO molecular medicine 13 (9) (2021)
Razieh Kamali-Jamil, Ester Vázquez-Fernández, Brian Tancowny, Vineet Rathod, Sara Amidian, Xiongyao Wang, Xinli Tang, Andrew Fang, Assunta Senatore, Simone Hornemann, Sandor Dudas, Adriano Aguzzi, Howard S Young, Holger Wille
The ultrastructure of infectious L-type bovine spongiform encephalopathy prions constrains molecular models. PLoS pathogens 17 (6) (2021)
Daniel Heinzer, Merve Avar, Daniel Patrick Pease, Ashutosh Dhingra, Jiang-An Yin, Elke Schaper, Berre Doğançay, Marc Emmenegger, Anna Spinelli, Kevin Maggi, Andra Chincisan, Simon Mead, Simone Hornemann, Peter Heutink, Adriano Aguzzi
Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference. PLoS pathogens 17 (10) (2021)
Maximo Sanz-Hernandez, Joseph D Barritt, Jens Sobek, Simone Hornemann, Adriano Aguzzi, Alfonso De Simone
Mechanism of misfolding of the human prion protein revealed by a pathological mutation. Proceedings of the National Academy of Sciences of the United States of America 118 (12) (2021)
Karl J Frontzek, Manfredi Carta, Marco Losa, Mirka Epskamp, Georg Meisl, Alice Anane, Jean-Philippe Brandel, Ulrike Camenisch, Joaquín Castilla, Stéphane Haïk, Tuomas P J Knowles, Ewald Lindner, Andreas Lutterotti, Eric Vallabh Minikel, Ignazio Roiter, Jiri G Safar, Raquel Sanchez-Valle, Dana Žáková, Simone Hornemann, Adriano Aguzzi, null null
Autoantibodies against the prion protein in individuals with PRNP mutations. Neurology 95 (14) (2020)
Assunta Senatore, Karl J Frontzek, Marc Emmenegger, Andra Chincisan, Marco Losa, Regina Rose Reimann, Geraldine Horny, Jingjing Guo, Sylvie Fels, Silvia Sorce, Caihong Zhu, Nathalie George, Stefan Ewert, Thomas Pietzonka, Simone Hornemann, Adriano Aguzzi
Protective anti-prion antibodies in human immunoglobulin repertoires. EMBO molecular medicine 12 (9) (2020)
Silvia Sorce, Mario Nuvolone, Giancarlo Russo, Andra Chincisan, Daniel Heinzer, Merve Avar, Manuela Pfammatter, Petra Schwarz, Mirzet Delic, Micha Müller, Simone Hornemann, Despina Sanoudou, Claudia Scheckel, Adriano Aguzzi
Genome-wide transcriptomics identifies an early preclinical signature of prion infection. PLoS pathogens 16 (6) (2020)
Simone Hornemann, Petra Schwarz, Elisabeth J Rushing, Michael D Connolly, Ronald N Zuckermann, Alice Y Yam, Adriano Aguzzi
Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads. PloS one 14 (9) (2019)
Marco Bardelli, Karl J Frontzek, Luca Simonelli, Simone Hornemann, Mattia Pedotti, Federica Mazzola, Manfredi Carta, Valeria Eckhardt, Rocco D'Antuono, Tommaso Virgilio, Santiago F González, Adriano Aguzzi, Luca Varani
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity. PLoS pathogens 14 (10) (2018)
Anne K Schütz, Simone Hornemann, Marielle A Wälti, Ladina Greuter, Cinzia Tiberi, Riccardo Cadalbert, Matthias Gantner, Roland Riek, Per Hammarström, K Peter R Nilsson, Anja Böckmann, Adriano Aguzzi, Beat H Meier
Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore. ACS chemical neuroscience 9 (3) (2017)
Manuela Pfammatter, Maria Andreasen, Georg Meisl, Christopher G Taylor, Jozef Adamcik, Sreenath Bolisetty, Antoni Sánchez-Ferrer, David Klenerman, Christopher M Dobson, Raffaele Mezzenga, Tuomas P J Knowles, Adriano Aguzzi, Simone Hornemann
Absolute Quantification of Amyloid Propagons by Digital Microfluidics. Analytical chemistry 89 (22) (2017)