Karl J Frontzek (Karl Frontzek)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Topics

Blood Brain Barrier

Top Venues

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature 626 (8001) (2024)
Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature (2024)
Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature 626 (8001) (2024)
Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature (2024)
Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature 626 (8001) (2024)
Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature (2024)
Claudio L Togni, Karl J Frontzek, Maximilian Schubring-Giese, Lukas L Imbach, Ilijas Jelcic
Posttransplant Anti-GABA A Receptor Antibody-Associated Autoimmune Encephalitis. Neurology 102 (7) (2024)
Claudio L Togni, Karl J Frontzek, Maximilian Schubring-Giese, Lukas L Imbach, Ilijas Jelcic
Posttransplant Anti-GABA A Receptor Antibody-Associated Autoimmune Encephalitis. Neurology 102 (7) (2024)
Marian Hruska-Plochan, Vera I Wiersma, Katharina M Hembach, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma, Laura De Vos, Karl J Frontzek, Adriano Aguzzi, Tammaryn Lashley, Mark D Robinson, Theofanis Karayannis, Martin Müller, Andreas Hierlemann, Magdalini Polymenidou
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature 626 (8001) (2024)
Lia Hellwig, Muriel Brada, Ulrike Held, Cornelia Hagmann, Peter Bode, Karl J Frontzek, Bernhard Frey, Barbara Brotschi, Beate Grass
Association of perinatal sentinel events, placental pathology and cerebral MRI in neonates with hypoxic-ischemic encephalopathy receiving therapeutic hypothermia. Journal of perinatology : official journal of the California Perinatal Association 42 (7) (2022)
Daniel Kirschenbaum, Ehsan Dadgar-Kiani, Francesca Catto, Fabian F Voigt, Chiara Trevisan, Oliver Bichsel, Hamid Shirani, K Peter R Nilsson, Karl J Frontzek, Paolo Paganetti, Fritjof Helmchen, Jin Hyung Lee, Adriano Aguzzi
Whole-brain microscopy reveals distinct temporal and spatial efficacy of anti-Aβ therapies. EMBO molecular medicine (2022)
Karl J Frontzek, Marco Bardelli, Assunta Senatore, Anna Henzi, Regina R Reimann, Seden Bedir, Marika Marino, Rohanah Hussain, Simon Jurt, Georg Meisl, Mattia Pedotti, Federica Mazzola, Giuliano Siligardi, Oliver Zerbe, Marco Losa, Tuomas P J Knowles, Asvin Lakkaraju, Caihong Zhu, Petra Schwarz, Simone Hornemann, Matthew G Holt, Luca Simonelli, Luca Varani, Adriano Aguzzi
A conformational switch controlling the toxicity of the prion protein. Nature structural & molecular biology 29 (8) (2022)
Asvin K K Lakkaraju, Karl J Frontzek, Emina Lemes, Uli Herrmann, Marco Losa, Rajlakshmi Marpakwar, Adriano Aguzzi
Loss of PIKfyve drives the spongiform degeneration in prion diseases. EMBO molecular medicine 13 (9) (2021)
Luise Linsenmeier, Behnam Mohammadi, Mohsin Shafiq, Karl J Frontzek, Julia Bär, Amulya Nidhi Shrivastava, Markus Damme, Feizhi Song, Alexander Schwarz, Stefano Da Vela, Tania Massignan, Sebastian Jung, Angela Correia, Matthias Schmitz, Berta Puig, Simone Hornemann, Inga Zerr, Jörg Tatzelt, Emiliano Biasini, Paul Saftig, Michaela Schweizer, Dmitri I Svergun, Ladan Amin, Federica Mazzola, Luca Varani, Simrika Thapa, Sabine Gilch, Hermann M Schatzl, David A Harris, Antoine Triller, Marina Mikhaylova, Adriano Aguzzi, Hermann Clemens Altmeppen, Markus Glatzel
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies. Science advances 7 (48) (2021)
Karl J Frontzek, Manfredi Carta, Marco Losa, Mirka Epskamp, Georg Meisl, Alice Anane, Jean-Philippe Brandel, Ulrike Camenisch, Joaquín Castilla, Stéphane Haïk, Tuomas P J Knowles, Ewald Lindner, Andreas Lutterotti, Eric Vallabh Minikel, Ignazio Roiter, Jiri G Safar, Raquel Sanchez-Valle, Dana Žáková, Simone Hornemann, Adriano Aguzzi, null null
Autoantibodies against the prion protein in individuals with PRNP mutations. Neurology 95 (14) (2020)
Assunta Senatore, Karl J Frontzek, Marc Emmenegger, Andra Chincisan, Marco Losa, Regina Rose Reimann, Geraldine Horny, Jingjing Guo, Sylvie Fels, Silvia Sorce, Caihong Zhu, Nathalie George, Stefan Ewert, Thomas Pietzonka, Simone Hornemann, Adriano Aguzzi
Protective anti-prion antibodies in human immunoglobulin repertoires. EMBO molecular medicine 12 (9) (2020)
Daniel Kirschenbaum, Lukas L Imbach, Elisabeth J Rushing, Katrin B M Frauenknecht, Dominic Gascho, Benjamin V Ineichen, Emanuela Keller, Sibylle Kohler, Mona Lichtblau, Regina R Reimann, Katharina Schreib, Silvia Ulrich, Peter Steiger, Adriano Aguzzi, Karl J Frontzek
Intracerebral endotheliitis and microbleeds are neuropathological features of COVID-19. Neuropathology and applied neurobiology 47 (3) (2020)
Gianluca D'Agati, Elena María Cabello, Karl J Frontzek, Elisabeth J Rushing, Robin Klemm, Mark D Robinson, Richard M White, Christian Mosimann, Alexa Burger
Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish. Disease models & mechanisms 12 (7) (2019)
Marco Bardelli, Karl J Frontzek, Luca Simonelli, Simone Hornemann, Mattia Pedotti, Federica Mazzola, Manfredi Carta, Valeria Eckhardt, Rocco D'Antuono, Tommaso Virgilio, Santiago F González, Adriano Aguzzi, Luca Varani
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity. PLoS pathogens 14 (10) (2018)