Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines.
Timothy W ClarkJillian MohanMichael R ShortreedKirsten ObernierMohammad Sadnan Al ManirChristopher P ChurasAmir DailamyYesh DoctorAntoine ForgetJan Niklas HansenMengzhou HuJoanna LenkiewiczMaxwell Adam LevinsonCharlotte MarquezSami NourreddineJustin NiestroyDexter PrattGege QianSwathi ThakerJean-Christophe Bélisle-PiponCynthia A BrandtJake ChenYing DingSamah Jamal FodehNevan J KroganEmma LundbergPrashant MaliPamela Payne-FosterSarah Jane RatcliffeVardit RavitskyAndrej SaliWade L SchulzTrey IdekerPublished in: bioRxiv : the preprint server for biology (2024)
This article describes the Cell Maps for Artificial Intelligence (CM4AI) project and its goals, methods, standards, current datasets, software tools , status, and future directions. CM4AI is the Functional Genomics Data Generation Project in the U.S. National Institute of Health's (NIH) Bridge2AI program. Its overarching mission is to produce ethical, AI-ready datasets of cell architecture, inferred from multimodal data collected for human cell lines, to enable transformative biomedical AI research.