Mitophagy suppression by miquelianin-rich lotus leaves extract induces "beiging" of white fat via AMPK/DRP1-PINK1/PARKIN signaling axis.

Zhenyu WangTian YangMaomao ZengZhaojun WangQiuming ChenJie ChenMark ChristianZhiyong He

Published in: Journal of the science of food and agriculture (2023)

Our data reveal a novel mechanism underlying the anti-obesity effect of LLE, namely the induction of white fat beiging via AMPK/DRP1/mitophagy signaling. This article is protected by copyright. All rights reserved.

Keyphrases

adipose tissue
skeletal muscle
insulin resistance
metabolic syndrome
type diabetes
fatty acid
weight loss
nlrp inflammasome
oxidative stress
protein kinase
genome wide
single cell
big data
high fat diet induced
body mass index
data analysis