Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Damon A HofmanJorge Ruiz-OreraIan YannuzziRakesh MurugesanAdam BrownKarl R ClauserAlexandra-Larisa ConduratJip T van DinterSem A G EngelsAmy GoodaleJasper van der LugtTanaz AbidLi WangKevin N ZhouJayne VogelzangKeith L LigonTimothy N PhoenixJennifer A RothDavid E RootNorbert HübnerTodd R GolubPratiti BandopadhayaySebastiaan van HeeschJohn R PrensnerPublished in: bioRxiv : the preprint server for biology (2023)
Ribo-seq reveals widespread translation of non-canonical ORFs in medulloblastomaHigh-resolution CRISPR tiling reveals uORF functions in medulloblastomaASNSD1-uORF controls downstream pathways with the prefoldin-like complexASNSD1-uORF is necessary for medulloblastoma cell survival.