Todd R Golub (Todd Golub)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 46

Top Venues

Nature genetics

Science (New York, N.Y.)

Nature communications

Nature

This page only lists publications with an associated author ORCID identifier.

Publications

Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Justin Rhoades, Jesse D Kirkpatrick, Sangeeta N Bhatia, Ava P Soleimany, Todd R Golub, John Christopher Love, Sangeeta N Bhatia, Viktor A Adalsteinsson
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies. Science (New York, N.Y.) 383 (6680) (2024)
Ulrike Rauh, Guo Wei, Michael Serrano-Wu, Georgios Kosmidis, Stefan Kaulfuss, Franziska Siegel, Kai Thede, James McFarland, Christopher T Lemke, Nicolas Werbeck, Katrin Nowak-Reppel, Sabine Pilari, Stephan Menz, Matthias Ocker, Weiqun Zhang, Kyle Davis, Guillaume Poncet-Montange, Jennifer A Roth, Douglas S Daniels, Virendar K Kaushik, Brian Hubbard, Karl Ziegelbauer, Todd R Golub
BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models. Nature cancer (2024)
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Justin Rhoades, Jesse D Kirkpatrick, Sangeeta N Bhatia, Ava P Soleimany, Todd R Golub, John Christopher Love, Sangeeta N Bhatia, Viktor A Adalsteinsson
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies. Science (New York, N.Y.) 383 (6680) (2024)
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Justin Rhoades, Jesse D Kirkpatrick, Sangeeta N Bhatia, Ava P Soleimany, Todd R Golub, John Christopher Love, Sangeeta N Bhatia, Viktor A Adalsteinsson
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies. Science (New York, N.Y.) 383 (6680) (2024)
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Justin Rhoades, Jesse D Kirkpatrick, Sangeeta N Bhatia, Ava P Soleimany, Todd R Golub, John Christopher Love, Sangeeta N Bhatia, Viktor A Adalsteinsson
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies. Science (New York, N.Y.) 383 (6680) (2024)
Ulrike Rauh, Guo Wei, Michael Serrano-Wu, Georgios Kosmidis, Stefan Kaulfuss, Franziska Siegel, Kai Thede, James McFarland, Christopher T Lemke, Nicolas Werbeck, Katrin Nowak-Reppel, Sabine Pilari, Stephan Menz, Matthias Ocker, Weiqun Zhang, Kyle Davis, Guillaume Poncet-Montange, Jennifer A Roth, Douglas S Daniels, Virendar K Kaushik, Brian Hubbard, Karl Ziegelbauer, Todd R Golub
BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models. Nature cancer (2024)
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Justin Rhoades, Jesse D Kirkpatrick, Sangeeta N Bhatia, Ava P Soleimany, Todd R Golub, John Christopher Love, Sangeeta N Bhatia, Viktor A Adalsteinsson
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies. Science (New York, N.Y.) 383 (6680) (2024)
Jin H Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E Shoag, Gilad D Evrony, Heather A Parsons, Erica L Mayer, G Mike Makrigiorgos, Todd R Golub, Viktor A Adalsteinsson
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity. Nature genetics 55 (5) (2023)
Christina K Baumgartner, Hakimeh Ebrahimi-Nik, Arvin Iracheta-Vellve, Keith M Hamel, Kira E Olander, Thomas G R Davis, Kathleen A McGuire, Geoff T Halvorsen, Omar I Avila, Chirag H Patel, Sarah Y Kim, Ashwin V Kammula, Audrey J Muscato, Kyle Halliwill, Prasanthi Geda, Kelly L Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D Yeary, James C Patti, Tyler M Balon, Rebecca Mathew, Carey Backus, Domenick E Kennedy, Angeline Chen, Kenton Longenecker, Joseph T Klahn, Cara L Hrusch, Navasona Krishnan, Charles W Hutchins, Jax P Dunning, Marinka Bulic, Payal Tiwari, Kayla J Colvin, Cun Lan Chuong, Ian C Kohnle, Matthew G Rees, Andrew Boghossian, Melissa A Ronan, Jennifer A Roth, Meng-Ju Wu, Juliette S M T Suermondt, Nelson H Knudsen, Collins K Cheruiyot, Debattama R Sen, Gabriel K Griffin, Todd R Golub, Nabeel El-Bardeesy, Joshua H Decker, Yi Yang, Magali Guffroy, Stacey Fossey, Patricia Trusk, Im-Meng Sun, Yue Liu, Wei Qiu, Qi Sun, Marcia N Paddock, Elliot P Farney, Mark A Matulenko, Clay Beauregard, Jennifer M Frost, Kathleen B Yates, Philip R Kym, Robert T Manguso
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity. Nature (2023)
Jin H Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E Shoag, Gilad D Evrony, Heather A Parsons, Erica L Mayer, G Mike Makrigiorgos, Todd R Golub, Viktor A Adalsteinsson
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity. Nature genetics 55 (5) (2023)
Jin H Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E Shoag, Gilad D Evrony, Heather A Parsons, Erica L Mayer, G Mike Makrigiorgos, Todd R Golub, Viktor A Adalsteinsson
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity. Nature genetics 55 (5) (2023)
Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R Clauser, Alexandra-Larisa Condurat, Jip T van Dinter, Sem A G Engels, Amy Goodale, Jasper van der Lugt, Tanaz Abid, Li Wang, Kevin N Zhou, Jayne Vogelzang, Keith L Ligon, Timothy N Phoenix, Jennifer A Roth, David E Root, Norbert Hübner, Todd R Golub, Pratiti Bandopadhayay, Sebastiaan van Heesch, John R Prensner
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma. bioRxiv : the preprint server for biology (2023)
Jin H Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E Shoag, Gilad D Evrony, Heather A Parsons, Erica L Mayer, G Mike Makrigiorgos, Todd R Golub, Viktor A Adalsteinsson
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity. Nature genetics 55 (5) (2023)
Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R Clauser, Alexandra-Larisa Condurat, Jip T van Dinter, Sem A G Engels, Amy Goodale, Jasper van der Lugt, Tanaz Abid, Li Wang, Kevin N Zhou, Jayne Vogelzang, Keith L Ligon, Timothy N Phoenix, Jennifer A Roth, David E Root, Norbert Hübner, Todd R Golub, Pratiti Bandopadhayay, Sebastiaan van Heesch, John R Prensner
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma. bioRxiv : the preprint server for biology (2023)
Jin H Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E Shoag, Gilad D Evrony, Heather A Parsons, Erica L Mayer, G Mike Makrigiorgos, Todd R Golub, Viktor A Adalsteinsson
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity. Nature genetics (2023)
Peter Tsvetkov, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, Lena M Joesch-Cohen, Ranad Humeidi, Ryan D Spangler, John K Eaton, Evgeni Frenkel, Mustafa Kocak, Steven M Corsello, Svetlana Lutsenko, Naama Kanarek, Sandro Santagata, Todd R Golub
Copper induces cell death by targeting lipoylated TCA cycle proteins. Science (New York, N.Y.) 375 (6586) (2022)
Eshini Panditharatna, Joana G Marques, Tingjian Wang, Maria C Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V Dharia, Deyao Li, Samantha E Hoffman, Guillaume Kugener, McKenzie L Shaw, Hafsa M Mire, Olivia A Hack, Joshua M Dempster, Caleb A Lareau, Lingling Dai, Logan H Sigua, Michael A Quezada, Ann-Catherine J Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Frederica Piccioni, John G Doench, David E Root, Jamie N Anastas, Kristen L Jones, Amy Saur Conway, Sylwia A Stopka, Michael S Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P Jerome, Nathan D Mathewson, Sirano Dhe-Paganon, Mario L Suvà, Angel Montero Carcaboso, Cinzia Lavarino, Jaume Catala-Mora, Quang-De Nguyen, Keith L Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y R Agar, Kimberly Stegmaier, Charles D Stiles, Michelle Monje, Todd R Golub, Jun Qi, Mariella G Filbin
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. Cancer discovery 12 (12) (2022)
Gregory Gydush, Erica Nguyen, Jin H Bae, Timothy Blewett, Justin Rhoades, Sarah C Reed, Douglas Shea, Kan Xiong, Ruolin Liu, Fangyan Yu, Ka Wai Leong, Atish D Choudhury, Daniel G Stover, Sara M Tolaney, Ian E Krop, John Christopher Love, Heather A Parsons, G Mike Makrigiorgos, Todd R Golub, Viktor A Adalsteinsson
Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth. Nature biomedical engineering 6 (3) (2022)
Daniel P Bondeson, Brenton R Paolella, Adhana Asfaw, Michael V Rothberg, Thomas A Skipper, Carly Langan, Gabriel Mesa, Alfredo Gonzalez, Lauren E Surface, Kentaro Ito, Mariya Kazachkova, William N Colgan, Allison Warren, Joshua M Dempster, John Michael Krill-Burger, Maria Ericsson, Andrew A Tang, Iris Fung, Emily S Chambers, Mai Abdusamad, Nancy Dumont, John G Doench, Federica Piccioni, David E Root, Jesse S Boehm, William C Hahn, Michael Mannstadt, James M McFarland, Francisca Vazquez, Todd R Golub
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nature cancer 3 (6) (2022)
Daniel P Bondeson, Zachary Mullin-Bernstein, Sydney Oliver, Thomas A Skipper, Thomas C Atack, Nolan Bick, Meilani Ching, Andrew A Guirguis, Jason Kwon, Carly Langan, Dylan Millson, Brenton R Paolella, Kevin Tran, Sarah J Wie, Francisca Vazquez, Zuzana Tothova, Todd R Golub, William R Sellers, Alessandra Ianari
Systematic profiling of conditional degron tag technologies for target validation studies. Nature communications 13 (1) (2022)
Yael Cohen-Sharir, James M McFarland, Mai Abdusamad, Carolyn Marquis, Sara V Bernhard, Mariya Kazachkova, Helen Tang, Marica R Ippolito, Kathrin Laue, Johanna Zerbib, Heidi L H Malaby, Andrew Jones, Lisa-Marie Stautmeister, Irena Bockaj, René Wardenaar, Nicholas Lyons, Ankur K Nagaraja, Adam J Bass, Diana Carolina Johanna Spierings, Floris Foijer, Rameen Beroukhim, Stefano Santaguida, Todd R Golub, Jason Stumpff, Zuzana Storchová, Uri Ben-David
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition. Nature 590 (7846) (2021)
Michal Sheffer, Emily Lowry, Nicky Beelen, Minasri Borah, Suha Naffar-Abu Amara, Chris C Mader, Jennifer A Roth, Aviad Tsherniak, Samuel S Freeman, Olga Dashevsky, Sara Gandolfi, Samantha Bender, Jordan G Bryan, Cong Zhu, Li Wang, Ifrah Tariq, Govinda M Kamath, Ricardo De Matos Simoes, Eugen Dhimolea, Channing Yu, Yiguo Hu, Olli Dufva, Marios Giannakis, Vasilis Syrgkanis, Ernest Fraenkel, Todd R Golub, Rizwan Romee, Mohamed El Missiry, Aedin C Culhane, Lotte Wieten, Constantine S Mitsiades
Genome-scale screens identify factors regulating tumor cell responses to natural killer cells. Nature genetics 53 (8) (2021)
Neekesh V Dharia, Guillaume Kugener, Lillian M Guenther, Clare F Malone, Adam D Durbin, Andrew L Hong, Thomas P Howard, Pratiti Bandopadhayay, Caroline S Wechsler, Iris Fung, Allison C Warren, Joshua M Dempster, John Michael Krill-Burger, Brenton R Paolella, Phoebe Moh, Nishant Jha, Andrew Tang, Phillip G Montgomery, Jesse S Boehm, William C Hahn, Charles W M Roberts, James M McFarland, Aviad Tsherniak, Todd R Golub, Francisca Vazquez, Kimberly Stegmaier
A first-generation pediatric cancer dependency map. Nature genetics 53 (4) (2021)
John R Prensner, Oana M Enache, Victor Luria, Karsten Krug, Karl R Clauser, Joshua M Dempster, Amir Karger, Li Wang, Karolina Stumbraite, Vickie M Wang, Ginevra Botta, Nicholas J Lyons, Amy Goodale, Zohra Kalani, Briana Fritchman, Adam Brown, Douglas Alan, Thomas Green, Xiaoping Yang, Jacob D Jaffe, Jennifer A Roth, Federica Piccioni, Marc W Kirschner, Zhe Ji, David E Root, Todd R Golub
Noncanonical open reading frames encode functional proteins essential for cancer cell survival. Nature biotechnology 39 (6) (2021)
Oana M Enache, Veronica Rendo, Mai Abdusamad, Daniel Lam, Desiree Davison, Sangita Pal, Naomi Currimjee, Julian Hess, Sasha Pantel, Anwesha Nag, Aaron R Thorner, John G Doench, Francisca Vazquez, Rameen Beroukhim, Todd R Golub, Uri Ben-David
Cas9 activates the p53 pathway and selects for p53-inactivating mutations. Nature genetics 52 (7) (2020)
Mikołaj Słabicki, Zuzanna Kozicka, Georg Petzold, Yen-Der Li, Manisha Manojkumar, Richard D Bunker, Katherine Aleisha Donovan, Quinlan L Sievers, Jonas Koeppel, Dakota Suchyta, Adam S Sperling, Emma C Fink, Jessica A Gasser, Li R Wang, Steven M Corsello, Rob S Sellar, Max Jan, Dennis Gillingham, Claudia Scholl, Stefan Fröhling, Todd R Golub, Eric S Fischer, Nicolas H Thomä, Benjamin L Ebert
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature 585 (7824) (2020)
Corrie A Painter, Esha Jain, Brett N Tomson, Michael Dunphy, Rachel E Stoddard, Beena S Thomas, Alyssa L Damon, Shahrayz Shah, Dewey Kim, Jorge Gómez Tejeda Zañudo, Jason L Hornick, Yen-Lin Chen, Priscilla Merriam, Chandrajit P Raut, George D Demetri, Brian A Van Tine, Eric S Lander, Todd R Golub, Nikhil Wagle
The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research. Nature medicine 26 (2) (2020)
James M McFarland, Brenton R Paolella, Allison Warren, Kathryn R Geiger-Schuller, Tsukasa Shibue, Michael Rothberg, Olena Kuksenko, William N Colgan, Andrew Jones, Emily Chambers, Danielle Dionne, Samantha Bender, Brian M Wolpin, Mahmoud Ghandi, Itay Tirosh, Orit Rozenblatt-Rosen, Jennifer A Roth, Todd R Golub, Aviv Regev, Andrew J Aguirre, Francisca Vazquez, Aviad Tsherniak
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action. Nature communications 11 (1) (2020)
Xin Jin, Zelalem Demere, Karthik Nair, Ahmed Ali, Gino B Ferraro, Ted Natoli, Amy Deik, Lia Petronio, Andrew A Tang, Cong Zhu, Li Wang, Danny Rosenberg, Vamsi Mangena, Jennifer Roth, Kwanghun Chung, Rakesh K Jain, Andrew T Chan, Matthew G Vander Heiden, Todd R Golub
A metastasis map of human cancer cell lines. Nature 588 (7837) (2020)
Peter Tsvetkov, Alexandre Detappe, Kai Cai, Heather R Keys, Zarina Brune, Weiwen Ying, Prathapan Thiru, Mairead Reidy, Guillaume Kugener, Jordan Rossen, Mustafa Kocak, Nora Kory, Aviad Tsherniak, Sandro Santagata, Luke Whitesell, Irene M Ghobrial, John L Markley, Susan Lindquist, Todd R Golub
Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nature chemical biology 15 (7) (2019)
Kamal R Abdul Azeez, Sneha Chatterjee, Channing Yu, Todd R Golub, Frank Sobott, Jonathan M Elkins
Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP. Nature communications 10 (1) (2019)
Joshua M Dempster, Clare Pacini, Sasha Pantel, Fiona M Behan, Thomas Green, John Michael Krill-Burger, Charlotte M Beaver, Scott T Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G Doench, Kosuke Yusa, Francisca Vazquez, Leopold Parts, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets. Nature communications 10 (1) (2019)
Aparna R Parikh, Ignaty Leshchiner, Liudmila Elagina, Lipika Goyal, Chaya Levovitz, Giulia Siravegna, Dimitri Livitz, Kahn Rhrissorrakrai, Elizabeth E Martin, Emily E Van Seventer, Megan Hanna, Kara Slowik, Filippo Utro, Christopher J Pinto, Alicia Wong, Brian P Danysh, Ferran Fece de la Cruz, Isobel J Fetter, Brandon A Nadres, Heather A Shahzade, Jill N Allen, Lawrence S Blaszkowsky, Jeffrey W Clark, Bruce Giantonio, Janet E Murphy, Ryan D Nipp, Eric Roeland, David P Ryan, Colin D Weekes, Eunice L Kwak, Jason E Faris, Jennifer Y Wo, François Aguet, Ipsita Dey-Guha, Mehlika Hazar-Rethinam, Dora Dias-Santagata, David Tsai Ting, Andrew X Zhu, Theodore S Hong, Todd R Golub, A John Iafrate, Viktor A Adalsteinsson, Alberto Bardelli, Laxmi Parida, Dejan Juric, Gad A Getz, Ryan B Corcoran
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. Nature medicine 25 (9) (2019)
Uri Ben-David, Rameen Beroukhim, Todd R Golub
Genomic evolution of cancer models: perils and opportunities. Nature reviews. Cancer 19 (2) (2019)
Adam D Durbin, Mark W Zimmerman, Neekesh V Dharia, Brian J Abraham, Amanda Balboni Iniguez, Nina Weichert-Leahey, Shuning He, John M Krill-Burger, David E Root, Francisca Vazquez, Aviad Tsherniak, William C Hahn, Todd R Golub, Richard A Young, A Thomas Look, Kimberly Stegmaier
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nature genetics 50 (9) (2018)
James M McFarland, Zandra V Ho, Guillaume Kugener, Joshua M Dempster, Phillip G Montgomery, Jordan G Bryan, John Michael Krill-Burger, Thomas M Green, Francisca Vazquez, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Aviad Tsherniak
Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration. Nature communications 9 (1) (2018)
Young-Gyun Park, Chang Ho Sohn, Ritchie Chen, Margaret McCue, Dae Hee Yun, Gabrielle T Drummond, Taeyun Ku, Nicholas B Evans, Hayeon Caitlyn Oak, Wendy Trieu, Heejin Choi, Xin Jin, Varoth Lilascharoen, Ji Wang, Matthias C Truttmann, Helena W Qi, Hidde L Ploegh, Todd R Golub, Shih-Chi Chen, Matthew P Frosch, Heather J Kulik, Byung Kook Lim, Kwanghun Chung
Protection of tissue physicochemical properties using polyfunctional crosslinkers. Nature biotechnology (2018)
Mariella G Filbin, Michael Mints, Volker Hovestadt, McKenzie L Shaw, Leah E Escalante, Nathan D Mathewson, Cyril Neftel, Nelli Frank, Kristine Pelton, Christine M Hebert, Christine Haberler, Keren Yizhak, Johannes Gojo, Kristof Egervari, Christopher Mount, Peter van Galen, Dennis M Bonal, Quang-De Nguyen, Alexander Beck, Claire Sinai, Thomas Czech, Christian Dorfer, Liliana Goumnerova, Cinzia Lavarino, Angel Montero Carcaboso, Jaume Mora, Ravindra Mylvaganam, Christina C Luo, Andreas Peyrl, Mara Popović, Amedeo A Azizi, Tracy T Batchelor, Matthew P Frosch, Maria Martinez-Lage, Mark W Kieran, Pratiti Bandopadhayay, Rameen Beroukhim, Gerhard Fritsch, Gad A Getz, Orit Rozenblatt-Rosen, Kai W Wucherpfennig, David N Louis, Michelle Monje, Irene Slavc, Keith L Ligon, Todd R Golub, Aviv Regev, Bradley E Bernstein, Mario L Suvà
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.) 360 (6386) (2018)
Bjoern Chapuy, Chip Stewart, Andrew J Dunford, Jaegil Kim, Atanas Kamburov, Robert A Redd, Mike S Lawrence, Margaretha G M Roemer, Amy J Li, Marita Ziepert, Annette M Staiger, Jeremiah A Wala, Matthew D Ducar, Ignaty Leshchiner, Ester Rheinbay, Amaro Taylor-Weiner, Caroline A Coughlin, Julian M Hess, Chandra S Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam A Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, Brian K Link, Anne J Novak, James R Cerhan, Thomas M Habermann, Reiner Siebert, Andreas Rosenwald, Aaron R Thorner, Matthew L Meyerson, Todd R Golub, Rameen Beroukhim, Gerald G Wulf, German Ott, Scott J Rodig, Stefano Monti, Donna S Neuberg, Markus Loeffler, Michael Pfreundschuh, Lorenz Trümper, Gad A Getz, Margaret A Shipp
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nature medicine 24 (5) (2018)
Leore T Geller, Michal Barzily-Rokni, Tal Danino, Oliver H Jonas, Noam Shental, Deborah Nejman, Nancy S Gavert, Yaara Zwang, Zachary A Cooper, Kevin Shee, Christoph A Thaiss, Alexandre Reuben, Jonathan Livny, Roi Avraham, Dennie T Frederick, Matteo Ligorio, Kelly Chatman, Stephen E Johnston, Carrie M Mosher, Alexander Brandis, Garold Fuks, Candice R Gurbatri, Vancheswaran Gopalakrishnan, Michael P Kim, Mark W Hurd, Matthew Katz, Jason B Fleming, Anirban Maitra, David A Smith, Matt Skalak, Jeffrey Bu, Monia Michaud, Sunia A Trauger, Iris Barshack, Talia Golan, Judith Sandbank, Keith T Flaherty, Anna Mandinova, Wendy S Garrett, Sarah P Thayer, Cristina R Ferrone, Curtis Huttenhower, Sangeeta N Bhatia, Dirk Gevers, Jennifer A Wargo, Todd R Golub, Ravid Straussman
Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science (New York, N.Y.) 357 (6356) (2018)
Vasileios Stathias, Anna M Jermakowicz, Marie E Maloof, Michele Forlin, Winston Walters, Robert K Suter, Michael A Durante, Sion L Williams, J William Harbour, Claude-Henry Volmar, Nicholas J Lyons, Claes Wahlestedt, Regina M Graham, Michael E Ivan, Ricardo J Komotar, Jann N Sarkaria, Aravind Subramanian, Todd R Golub, Stephan C Schürer, Nagi G Ayad
Drug and disease signature integration identifies synergistic combinations in glioblastoma. Nature communications 9 (1) (2018)
Mario Niepel, Marc Hafner, Qiaonan Duan, Zichen Wang, Evan O Paull, Mirra Chung, Xiaodong Lu, Joshua M Stuart, Todd R Golub, Aravind Subramanian, Avi Ma'ayan, Peter Karl Sorger
Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling. Nature communications 8 (1) (2017)
Viktor A Adalsteinsson, Gavin Ha, Samuel S Freeman, Atish D Choudhury, Daniel G Stover, Heather A Parsons, Gregory Gydush, Sarah C Reed, Denisse Rotem, Justin Rhoades, Denis Loginov, Dimitri Livitz, Daniel Rosebrock, Ignaty Leshchiner, Jaegil Kim, Chip Stewart, Mara Rosenberg, Joshua M Francis, Cheng-Zhong Zhang, Ofir Cohen, Coyin Oh, Huiming Ding, Paz Polak, Max Lloyd, Sairah Mahmud, Karla Helvie, Margaret S Merrill, Rebecca A Santiago, Edward P O'Connor, Seong H Jeong, Rachel Leeson, Rachel M Barry, Joseph F Kramkowski, Zhenwei Zhang, Laura Polacek, Jens G Lohr, Molly Schleicher, Emily Lipscomb, Andrea Saltzman, Nelly M Oliver, Lori Marini, Adrienne G Waks, Lauren C Harshman, Sara M Tolaney, Eliezer M Van Allen, Eric P Winer, Nancy U Lin, Mari Nakabayashi, Mary-Ellen Taplin, Cory M Johannessen, Levi A Garraway, Todd R Golub, Jesse S Boehm, Nikhil Wagle, Gad A Getz, J Christopher Love, Matthew L Meyerson
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. Nature communications 8 (1) (2017)
Andrew S Venteicher, Michael Mints, Christine Hebert, Keren Yizhak, Cyril Neftel, Mariella G Filbin, Volker Hovestadt, Leah E Escalante, McKenzie L Shaw, Christopher Rodman, Shawn M Gillespie, Danielle Dionne, Christina C Luo, Hiranmayi Ravichandran, Ravindra Mylvaganam, Christopher Mount, Maristela L Onozato, Brian V Nahed, Hiroaki Wakimoto, William T Curry, A John Iafrate, Miguel N Rivera, Matthew P Frosch, Todd R Golub, Priscilla K Brastianos, Gad A Getz, Anoop P Patel, Michelle Monje, Daniel P Cahill, Orit Rozenblatt-Rosen, David N Louis, Bradley E Bernstein, Aviv Regev, Mario L Suvà
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science (New York, N.Y.) 355 (6332) (2017)
Robin M Meyers, Jordan G Bryan, James M McFarland, Barbara A Weir, Ann E Sizemore, Han Xu, Neekesh V Dharia, Phillip G Montgomery, Glenn S Cowley, Sasha Pantel, Amy Goodale, Yenarae Lee, Levi D Ali, Guozhi Jiang, Rakela Lubonja, William F Harrington, Matthew Strickland, Ting Wu, Derek C Hawes, Victor A Zhivich, Meghan R Wyatt, Zohra Kalani, Jaime J Chang, Michael Okamoto, Kimberly Stegmaier, Todd R Golub, Jesse S Boehm, Francisca Vazquez, David E Root, William C Hahn, Aviad Tsherniak
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. Nature genetics 49 (12) (2017)
Uri Ben-David, Gavin Ha, Yuen-Yi Tseng, Noah F Greenwald, Coyin Oh, Juliann Shih, James M McFarland, Bang Wong, Jesse S Boehm, Rameen Beroukhim, Todd R Golub
Patient-derived xenografts undergo mouse-specific tumor evolution. Nature genetics 49 (11) (2017)

Todd R Golub.css-eqlu8i{font-size:small;padding-left:4px;} (Todd Golub)

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Todd R Golub (Todd Golub)