Login / Signup

Expanding Bromodomain Targeting into Neglected Parasitic Diseases.

Cynthia TallantPaul BamboroughChun-Wa ChungFrancisco Javier GamoRobert KirkpatrickChris LarminieJ Julio MartinRab PrinjhaInmaculada RiojaDaniel F SimolaRaquel GabarróFelix Calderon
Published in: ACS infectious diseases (2021)
This Perspective discusses the published data and recent developments in the research area of bromodomains in parasitic protozoa. Further work is needed to evaluate the tractability of this target class in the context of infectious diseases and launch drug discovery campaigns to identify and develop antiparasite drugs that can offer differentiated mechanisms of action.
Keyphrases
  • drug discovery
  • infectious diseases
  • electronic health record
  • cancer therapy
  • big data
  • randomized controlled trial
  • systematic review
  • machine learning
  • meta analyses
  • data analysis