Juergen Burhenne (Jürgen Burhenne)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 49

Top Venues

International journal of molecular sciences

Pharmaceutics

Clinical pharmacokinetics

Clinical and translational science

University of Heidelberg

University of Kassel (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Heidelberg Jan 01 2000

Germany

Head of the Analytical Chemistry Lab :: Department of Clinical Pharmacology and Pharmacoepidemiology

University of Kassel Nov 01 1993 - Dec 31 1999

Germany

Post Doc :: Department of Ecotoxicologic Chemistry

University of Kassel Sep 01 1990 - Oct 31 1993

Germany

PhD Student :: Department of Analytical Chemistry

Education History

University of Kassel Sep 01 1990 - Oct 31 1993

Germany

PHD :: Department of Analytical Chemistry

University of Kassel Oct 01 1985 - Oct 01 1990

Germany

MSC :: Chemistry Department

Publications

Juan Pablo Rigalli, Anna Gagliardi, Klara Diester, Gzona Bajraktari-Sylejmani, Antje Blank, Juergen Burhenne, Alexander Lenard, Lars Werntz, Andrea Huppertz, Lena Münch, Janica Margrit Wendt, Max Sauter, Walter Emil Haefeli, Johanna Weiss
Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP). International journal of molecular sciences 25 (7) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Nicolas Hohmann, Anna S Friedrichs, Juergen Burhenne, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin. Clinical and translational science 17 (8) (2024)
Nicolas Hohmann, Anna S Friedrichs, Juergen Burhenne, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin. Clinical and translational science 17 (8) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Juan Pablo Rigalli, Anna Gagliardi, Klara Diester, Gzona Bajraktari-Sylejmani, Antje Blank, Juergen Burhenne, Alexander Lenard, Lars Werntz, Andrea Huppertz, Lena Münch, Janica Margrit Wendt, Max Sauter, Walter Emil Haefeli, Johanna Weiss
Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP). International journal of molecular sciences 25 (7) (2024)
Juan Pablo Rigalli, Anna Gagliardi, Klara Diester, Gzona Bajraktari-Sylejmani, Antje Blank, Juergen Burhenne, Alexander Lenard, Lars Werntz, Andrea Huppertz, Lena Münch, Janica Margrit Wendt, Max Sauter, Walter Emil Haefeli, Johanna Weiss
Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP). International journal of molecular sciences 25 (7) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics (2024)
Amin Muhareb, Antje Blank, Andreas Daniel Meid, Kathrin I Foerster, Felicitas Stoll, Juergen Burhenne, Walter Emil Haefeli, Gerd Mikus
CYP3A and CYP2C19 Activity Determined by Microdosed Probe Drugs Accurately Predict Voriconazole Clearance in Healthy Adults. Clinical pharmacokinetics (2023)
Cindy Bay, Gzona Bajraktari-Sylejmani, Walter Emil Haefeli, Juergen Burhenne, Johanna Weiss, Max Sauter
Correction: Bay et al. Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC3A2) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine. Int. J. Mol. Sci. 2022, 23 , 3637. International journal of molecular sciences 24 (5) (2023)
Margaux Fresnais, Siwen Liang, Deniz Seven, Nevena Prodanovic, Julia Sundheimer, Walter Emil Haefeli, Juergen Burhenne, Rémi Longuespée
Desorption Kinetics Evaluation for the Development of Validated Desorption Electrospray Ionization-Mass Spectrometric Assays for Drug Quantification in Tissue Sections. International journal of molecular sciences 24 (10) (2023)
Evelyn Krohmer, Brit Silja Rohr, Felicitas Stoll, Katja S Gümüs, Mariano Bergamino, Gerd Mikus, Max Sauter, Juergen Burhenne, Johanna Weiss, Andreas Daniel Meid, David Czock, Antje Blank, Walter Emil Haefeli
Influence of a Short Course of Ritonavir Used as Booster in Antiviral Therapies Against SARS-CoV-2 on the Exposure of Atorvastatin and Rosuvastatin. Cardiovascular drugs and therapy (2023)
Max Sauter, Jonas Haag, Cindy Bay, Florian Leuschner, Walter Emil Haefeli, Tim Christian Kuhn, Juergen Burhenne
Bioanalysis of the Ex Vivo Labile PACE4 Inhibitory Peptide Ac-[d-Leu]LLLRVK-Amba in Whole Blood Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Quantification. Pharmaceutics 15 (12) (2023)
Xu Zhou, Jingyu An, Roma Kurilov, Benedikt Brors, Kai Hu, Teresa Peccerella, Stephanie Roessler, Katrin Pfütze, Angela Schulz, Stephan Wolf, Nicolas Hohmann, Dirk Theile, Max Sauter, Juergen Burhenne, Shigenori Ei, Ulrike Heger, Oliver Strobel, Simon T Barry, Christoph Springfeld, Christine Tjaden, Frank Bergmann, Markus Büchler, Thilo Hackert, Franco Fortunato, John P Neoptolemos, Peter Bailey
Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC. Nature cancer (2023)
Margaux Fresnais, Ina Jung, Uli B Klein, Dirk Theile, Siwen Liang, Walter E Haefeli, Juergen Burhenne, Rémi Longuespée
Quantification of Biologically Active DNA Alkylation in Temozolomide-Exposed Glioblastoma Cell Lines by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry: Method Development and Recommendations for Validation. ACS omega 8 (26) (2023)
Nicolas Hohmann, Martin Ronald Sprick, Azaz Ahmed, Juergen Burhenne, Marietta Kirchner, Lucian Le Cornet, Markus Kratzmann, Jacek Hajda, Albrecht Stenzinger, Karen Steindorf, Stefan Delorme, Heinz-Peter Schlemmer, Sabine Riethdorf, Ron van Schaik, Klaus Pantel, Jens Thomas Siveke, Thomas Seufferlein, Dirk Jäger, Walter Emil Haefeli, Flavia Carla Meotti, Christoph Springfeld
Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy. Clinical and translational science (2023)
Cindy Bay, Gzona Bajraktari-Sylejmani, Walter Emil Haefeli, Juergen Burhenne, Johanna Weiss, Max Sauter
Correction: Bay et al. Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC3A2) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine. Int. J. Mol. Sci. 2022, 23 , 3637. International journal of molecular sciences 24 (5) (2023)
Margaux Fresnais, Ina Jung, Uli B Klein, Aubry K Miller, Şevin Turcan, Walter Emil Haefeli, Juergen Burhenne, Rémi Longuespée
Important Requirements for Desorption/Ionization Mass Spectrometric Measurements of Temozolomide-Induced 2'-Deoxyguanosine Methylations in DNA. Cancers 15 (3) (2023)
Margaux Fresnais, Ina Jung, Uli B Klein, Aubry K Miller, Şevin Turcan, Walter Emil Haefeli, Juergen Burhenne, Rémi Longuespée
Important Requirements for Desorption/Ionization Mass Spectrometric Measurements of Temozolomide-Induced 2'-Deoxyguanosine Methylations in DNA. Cancers 15 (3) (2023)
Max Sauter, Jonas Haag, Cindy Bay, Florian Leuschner, Walter Emil Haefeli, Tim Christian Kuhn, Juergen Burhenne
Bioanalysis of the Ex Vivo Labile PACE4 Inhibitory Peptide Ac-[d-Leu]LLLRVK-Amba in Whole Blood Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Quantification. Pharmaceutics 15 (12) (2023)
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker Daniel, Mathias Haag, Matthias Schwab, Johannes Riffel, Florian Andre, Lenka Taylor, Johanna Weiss, Juergen Burhenne, Volker Cleeves, Walter E Haefeli, Antje Blank
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial. International journal of molecular sciences 23 (24) (2022)
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker Daniel, Mathias Haag, Matthias Schwab, Johannes Riffel, Florian Andre, Lenka Taylor, Johanna Weiss, Juergen Burhenne, Volker Cleeves, Walter E Haefeli, Antje Blank
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial. International journal of molecular sciences 23 (24) (2022)
Manuel Kraft, Kathrin I Foerster, Felix Wiedmann, Max Sauter, Amelie Paasche, Pablo L Blochberger, Baran Yesilgöz, Yannick L'hoste, Norbert Frey, Walter Emil Haefeli, Juergen Burhenne, Constanze Schmidt
Simultaneous Quantification and Pharmacokinetic Characterization of Doxapram and 2-Ketodoxapram in Porcine Plasma and Brain Tissue. Pharmaceutics 14 (4) (2022)
Margaux Fresnais, Siwen Liang, Marius Breitkopf, Joshua Raoul Lindner, Emmanuelle Claude, Steven Pringle, Pavel A Levkin, Konstantin Demir, Julia Benzel, Julia Sundheimer, Britta Statz, Kristian W Pajtler, Stefan M Pfister, Walter E Haefeli, Juergen Burhenne, Rémi Longuespée
Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections. Pharmaceuticals (Basel, Switzerland) 15 (6) (2022)
Gzona Bajraktari-Sylejmani, Teresa von Linde, Juergen Burhenne, Walter Emil Haefeli, Max Sauter, Johanna Weiss
Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides. Pharmaceutics 14 (8) (2022)
Romain Sigaud, Lisa Rösch, Charlotte Gatzweiler, Julia Benzel, Laura von Soosten, Heike Peterziel, Florian Selt, Sara Najafi, Simay Ayhan, Xenia F Gerloff, Nina Hofmann, Isabel Büdenbender, Lukas Schmitt, Kathrin I Foerster, Juergen Burhenne, Walter Emil Haefeli, Andrey Korshunov, Felix Sahm, Cornelis M van Tilburg, David T W Jones, Stefan M Pfister, Deborah Knoerzer, Brent L Kreider, Max Sauter, Kristian W Pajtler, Marc Zuckermann, Ina Oehme, Olaf Witt, Till Milde
The first-in-class ERK inhibitor ulixertinib shows promising activity in MAPK-driven pediatric low-grade glioma models. Neuro-oncology (2022)
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker Daniel, Mathias Haag, Matthias Schwab, Johannes Riffel, Florian Andre, Lenka Taylor, Johanna Weiss, Juergen Burhenne, Volker Cleeves, Walter E Haefeli, Antje Blank
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial. International journal of molecular sciences 23 (24) (2022)
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker Daniel, Mathias Haag, Matthias Schwab, Johannes Riffel, Florian Andre, Lenka Taylor, Johanna Weiss, Juergen Burhenne, Volker Cleeves, Walter E Haefeli, Antje Blank
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial. International journal of molecular sciences 23 (24) (2022)
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker Daniel, Mathias Haag, Matthias Schwab, Johannes Riffel, Florian Andre, Lenka Taylor, Johanna Weiss, Juergen Burhenne, Volker Cleeves, Walter E Haefeli, Antje Blank
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial. International journal of molecular sciences 23 (24) (2022)
Margaux Fresnais, Seda Karabulut, Yasmin Abou Zeed, Johannes Ungermann, Julia Benzel, Kristian W Pajtler, Stefan M Pfister, Walter Emil Haefeli, Juergen Burhenne, Rémi Longuespée
Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices-A Practical Example. Molecules (Basel, Switzerland) 27 (3) (2022)
Mareile H Breithaupt, Evelyn Krohmer, Lenka Taylor, Eva Koerner, Torsten Hoppe-Tichy, Juergen Burhenne, Kathrin I Foerster, Markus Dachtler, Gerald Huber, Rakesh Venkatesh, Karin Eggenreich, David Czock, Gerd Mikus, Antje Blank, Walter Emil Haefeli
Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers. European journal of clinical pharmacology 78 (12) (2022)
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker Daniel, Mathias Haag, Matthias Schwab, Johannes Riffel, Florian Andre, Lenka Taylor, Johanna Weiss, Juergen Burhenne, Volker Cleeves, Walter E Haefeli, Antje Blank
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial. International journal of molecular sciences 23 (24) (2022)
Cindy Bay, Gzona Bajraktari-Sylejmani, Walter Emil Haefeli, Juergen Burhenne, Johanna Weiss, Max Sauter
Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC2A3) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine. International journal of molecular sciences 23 (7) (2022)
Julia Benzel, Gzona Bajraktari-Sylejmani, Philipp Uhl, Abigail Davis, Sreenath Nair, Stefan M Pfister, Walter Emil Haefeli, Johanna Weiss, Juergen Burhenne, Kristian W Pajtler, Max Sauter
Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification. Pharmaceutics 13 (9) (2021)
Teresa von Linde, Gzona Bajraktari-Sylejmani, Walter Emil Haefeli, Juergen Burhenne, Johanna Weiss, Max Sauter
Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1. Pharmaceutics 13 (7) (2021)
Margaux Fresnais, Sevin Turcan, Dirk Theile, Johannes Ungermann, Yasmin Abou Zeed, Joshua Raoul Lindner, Marius Breitkopf, Juergen Burhenne, Walter Emil Haefeli, Rémi Longuespée
Approaching Sites of Action of Temozolomide for Pharmacological and Clinical Studies in Glioblastoma. Biomedicines 10 (1) (2021)
Margaux Fresnais, Juergen Burhenne, Walter E Haefeli, Rémi Longuespée
Desorption/Ionization-MS Methods for Drug Quantification in Biological Matrices and Their Validation Following Regulatory Guidance. Analytical chemistry 93 (19) (2021)
Margaux Fresnais, Esra Yildirim, Seda Karabulut, Dirk Jäger, Inka Zörnig, Julia Benzel, Kristian W Pajtler, Stefan M Pfister, Juergen Burhenne, Walter E Haefeli, Rémi Longuespée
Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives. Molecules (Basel, Switzerland) 26 (5) (2021)
Margaux Fresnais, Alexander Muck, Marius Majewsky, Britta Statz, Sonja Krausert, Julia Benzel, David Castel, Ludivine Le Dret, Stefan Pfister, Walter E Haefeli, Juergen Burhenne, Rémi Longuespée
Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling. Journal of the American Society for Mass Spectrometry 31 (3) (2020)
Rémi Longuespée, Dirk Theile, Margaux Fresnais, Juergen Burhenne, Johanna Weiss, Walter Emil Haefeli
Approaching sites of action of drugs in clinical pharmacology: New analytical options and their challenges. British journal of clinical pharmacology 87 (3) (2020)
Max Sauter, Juergen Burhenne, Walter Emil Haefeli, Philipp Uhl
An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids. Molecules (Basel, Switzerland) 25 (19) (2020)
Margaux Fresnais, André Roth, Kathrin I Foerster, Dirk Jäger, Stefan M Pfister, Walter Emil Haefeli, Juergen Burhenne, Rémi Longuespée
Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI-IM-MS/MS Assay. Cancers 12 (7) (2020)
Manuela Vay, Max Sauter, Gerd Mikus, Juergen Burhenne
Quantification of microdosed oral yohimbine and its major metabolite in human plasma in the picogram range. Bioanalysis 11 (16) (2019)
Andrea Huppertz, Christian Ott, Thomas Bruckner, Kathrin I Foerster, Juergen Burhenne, Johanna Weiss, Markus Zorn, Walter Emil Haefeli, David Czock
Prolonged-Release Tacrolimus Is Less Susceptible to Interaction With the Strong CYP3A Inhibitor Voriconazole in Healthy Volunteers. Clinical pharmacology and therapeutics 106 (6) (2019)
Andrea Huppertz, Lars Werntz, Andreas Daniel Meid, Kathrin I Foerster, Juergen Burhenne, David Czock, Gerd Mikus, Walter Emil Haefeli
Rivaroxaban and macitentan can be coadministered without dose adjustment but the combination of rivaroxaban and St John's wort should be avoided. British journal of clinical pharmacology 84 (12) (2018)
Kathrin I Foerster, Andrea Huppertz, Andreas D Meid, Oliver J Müller, Timolaos Rizos, Lisa Tilemann, Walter E Haefeli, Juergen Burhenne
Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC-MS/MS-Based Assay. Analytical chemistry 90 (15) (2018)
Juergen Burhenne, Lu Liu, Christoph E Heilig, Andreas D Meid, Margarete Leisen, Thomas Schmitt, Bernd Kasper, Walter E Haefeli, Gerd Mikus, Gerlinde Egerer
Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients. Cancer chemotherapy and pharmacology 80 (2) (2017)

Juergen Burhenne.css-eqlu8i{font-size:small;padding-left:4px;} (Jürgen Burhenne)

Publication Activity (10 Years)

Top Topics

Top Venues

Juergen Burhenne (Jürgen Burhenne)