Miguel Alcalde

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 33

Top Topics

High Throughput Sequencing

Hydrogen Peroxide

Molecular Dynamics Simulations

Top Venues

Journal of the American Chemical Society

Angewandte Chemie (International ed. in English)

Applied and environmental microbiology

Biotechnology and bioengineering

This page only lists publications with an associated author ORCID identifier.

Publications

Patricia Gomez de Santos, Alejandro González-Benjumea, Angela Fernandez-Garcia, Carmen Aranda, Yinqi Wu, Andrada But, Patricia Molina-Espeja, Diana M Mate, David Gonzalez Perez, Wuyuan Zhang, Jan Kiebist, Katrin Scheibner, Martin Hofrichter, Katarzyna Świderek, Francisco Javier Medrano, Julia Sanz-Aparicio, Frank Hollmann, Ana Gutiérrez, Miguel Alcalde
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Patricia Gomez de Santos, Alejandro González-Benjumea, Angela Fernandez-Garcia, Carmen Aranda, Yinqi Wu, Andrada But, Patricia Molina-Espeja, Diana M Mate, David Gonzalez Perez, Wuyuan Zhang, Jan Kiebist, Katrin Scheibner, Martin Hofrichter, Katarzyna Świderek, Francisco Javier Medrano, Julia Sanz-Aparicio, Frank Hollmann, Ana Gutiérrez, Miguel Alcalde
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society 145 (6) (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society 145 (6) (2023)
Thomas Hilberath, Remco van Oosten, Juliet Victoria, Hugo Brasselet, Miguel Alcalde, John M Woodley, Frank Hollmann
Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane. Organic process research & development 27 (7) (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society 145 (6) (2023)
Patricia Gomez de Santos, Alejandro González-Benjumea, Angela Fernandez-Garcia, Carmen Aranda, Yinqi Wu, Andrada But, Patricia Molina-Espeja, Diana M Mate, David Gonzalez Perez, Wuyuan Zhang, Jan Kiebist, Katrin Scheibner, Martin Hofrichter, Katarzyna Świderek, Francisco Javier Medrano, Julia Sanz-Aparicio, Frank Hollmann, Ana Gutiérrez, Miguel Alcalde
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Patricia Gomez de Santos, Alejandro González-Benjumea, Angela Fernandez-Garcia, Carmen Aranda, Yinqi Wu, Andrada But, Patricia Molina-Espeja, Diana M Mate, David Gonzalez Perez, Wuyuan Zhang, Jan Kiebist, Katrin Scheibner, Martin Hofrichter, Katarzyna Świderek, Francisco Javier Medrano, Julia Sanz-Aparicio, Frank Hollmann, Ana Gutiérrez, Miguel Alcalde
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society 145 (6) (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society 145 (6) (2023)
Patricia Gomez de Santos, Ivan Mateljak, Manh Dat Hoang, Sarel Jacob Fleishman, Frank Hollmann, Miguel Alcalde
Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions. Journal of the American Chemical Society 145 (6) (2023)
Shiran Barber-Zucker, Ivan Mateljak, Moshe Goldsmith, Meital Kupervaser, Miguel Alcalde, Sarel Jacob Fleishman
Designed High-Redox Potential Laccases Exhibit High Functional Diversity. ACS catalysis 12 (21) (2022)
Xiaomin Xu, Hugo Brasselet, Ewald P J Jongkind, Miguel Alcalde, Caroline E Paul, Frank Hollmann
A Peroxygenase-Alcohol Dehydrogenase Cascade Reaction to Transform Ethylbenzene Derivatives into Enantioenriched Phenylethanols. Chembiochem : a European journal of chemical biology 23 (6) (2022)
Luis I Gutierrez-Rus, Miguel Alcalde, Valeria A Risso, Jose M Sanchez-Ruiz
Efficient Base-Catalyzed Kemp Elimination in an Engineered Ancestral Enzyme. International journal of molecular sciences 23 (16) (2022)
Patricia Gomez de Santos, Alejandro González-Benjumea, Angela Fernandez-Garcia, Carmen Aranda, Yinqi Wu, Andrada But, Patricia Molina-Espeja, Diana M Mate, David Gonzalez Perez, Wuyuan Zhang, Jan Kiebist, Katrin Scheibner, Martin Hofrichter, Katarzyna Świderek, Francisco Javier Medrano, Julia Sanz-Aparicio, Frank Hollmann, Ana Gutiérrez, Miguel Alcalde
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angewandte Chemie (International ed. in English) (2022)
Xianke Sang, Feifei Tong, Zhi-Gang Zeng, Minghu Wu, Bo Yuan, Zhoutong Sun, Xiang Sheng, Ge Qu, Miguel Alcalde, Frank Hollmann, Wuyuan Zhang
A Biocatalytic Platform for the Synthesis of Enantiopure Propargylic Alcohols and Amines. Organic letters 24 (23) (2022)
Shiran Barber-Zucker, Vladimir Mindel, Eva Garcia-Ruiz, Jonathan J Weinstein, Miguel Alcalde, Sarel Jacob Fleishman
Stable and Functionally Diverse Versatile Peroxidases Designed Directly from Sequences. Journal of the American Chemical Society 144 (8) (2022)
Pascal Püllmann, Anja Knorrscheidt, Judith Münch, Paul R Palme, Wolfgang Hoehenwarter, Sylvestre Marillonnet, Miguel Alcalde, Bernhard Westermann, Martin J Weissenborn
A modular two yeast species secretion system for the production and preparative application of unspecific peroxygenases. Communications biology 4 (1) (2021)
Javier Martin-Diaz, Patricia Molina-Espeja, Martin Hofrichter, Frank Hollmann, Miguel Alcalde
Directed evolution of unspecific peroxygenase in organic solvents. Biotechnology and bioengineering 118 (8) (2021)
Patricia Gomez de Santos, Manh Dat Hoang, Jan Kiebist, Harald Kellner, René Ullrich, Katrin Scheibner, Martin Hofrichter, Christiane Liers, Miguel Alcalde
Functional Expression of Two Unusual Acidic Peroxygenases from Candolleomyces aberdarensis in Yeasts by Adopting Evolved Secretion Mutations. Applied and environmental microbiology 87 (19) (2021)
Fabio Tonin, Florian Tieves, Sébastien Willot, Anouska van Troost, Remco van Oosten, Stefaan Breestraat, Sander van Pelt, Miguel Alcalde, Frank Hollmann
Pilot-Scale Production of Peroxygenase from Agrocybe aegerita. Organic process research & development 25 (6) (2021)
Raul Mireles, Joaquin Ramirez-Ramirez, Miguel Alcalde, Marcela Ayala
Ether Oxidation by an Evolved Fungal Heme-Peroxygenase: Insights into Substrate Recognition and Reactivity. Journal of fungi (Basel, Switzerland) 7 (8) (2021)
Bernardo J Gomez-Fernandez, Valeria A Risso, Andres Rueda, Jose M Sanchez-Ruiz, Miguel Alcalde
Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases. Applied and environmental microbiology 86 (14) (2020)
Joaquin Ramirez-Ramirez, Javier Martin-Diaz, Berto Tejera, Miguel Alcalde, Marcela Ayala
Exploring the Role of Phenylalanine Residues in Modulating the Flexibility and Topography of the Active Site in the Peroxygenase Variant PaDa-I. International journal of molecular sciences 21 (16) (2020)
Abdulkadir Yayci, Alvaro Gomez Baraibar, Marco Krewing, Elena Fernandez Fueyo, Frank Hollmann, Miguel Alcalde, Ascensión Martínez-Márquez, Julia Elisabeth Bandow
Plasma-Driven in Situ Production of Hydrogen Peroxide for Biocatalysis. ChemSusChem 13 (8) (2020)
Bernardo J Gomez-Fernandez, Valeria A Risso, Andres Rueda, Jose M Sanchez-Ruiz, Miguel Alcalde
Correction for Gomez-Fernandez et al., "Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases". Applied and environmental microbiology 86 (17) (2020)
Simon J Freakley, Svenja Kochius, Jacqueline van Marwijk, Caryn Fenner, Richard J Lewis, Kai Baldenius, Sarel S Marais, Diederik Johannes Opperman, Susan T L Harrison, Miguel Alcalde, Martha Sophia Smit, Graham John Hutchings
A chemo-enzymatic oxidation cascade to activate C-H bonds with in situ generated H2O2. Nature communications 10 (1) (2019)
Ivan Mateljak, Austin Rice, Kevin Yang, Thierry Tron, Miguel Alcalde
The Generation of Thermostable Fungal Laccase Chimeras by SCHEMA-RASPP Structure-Guided Recombination in Vivo. ACS synthetic biology 8 (4) (2019)
Mercedes Ramirez-Escudero, Patricia Molina-Espeja, Patricia Gomez de Santos, Martin Hofrichter, Julia Sanz-Aparicio, Miguel Alcalde
Structural Insights into the Substrate Promiscuity of a Laboratory-Evolved Peroxygenase. ACS chemical biology 13 (12) (2018)
Javier Martin-Diaz, Carmen Paret, Eva García-Ruiz, Patricia Molina-Espeja, Miguel Alcalde
Shuffling the Neutral Drift of Unspecific Peroxygenase in Saccharomyces cerevisiae. Applied and environmental microbiology 84 (15) (2018)
Javier Viña-Gonzalez, Katarina Elbl, Xavier Ponte, Francisco Valero, Miguel Alcalde
Functional expression of aryl-alcohol oxidase in Saccharomyces cerevisiae and Pichia pastoris by directed evolution. Biotechnology and bioengineering 115 (7) (2018)
Wuyuan Zhang, Bastien O Burek, Elena Fernandez Fueyo, Miguel Alcalde, Jonathan Z Bloh, Frank Hollmann
Selective Activation of C-H Bonds in a Cascade Process Combining Photochemistry and Biocatalysis. Angewandte Chemie (International ed. in English) 56 (48) (2017)