Adam E Locke (Adam Locke)

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 31

Top Venues

Nature

Nature genetics

Nature communications

PLoS genetics

Washington University in Saint Louis School of Medicine

Emory University Laney Graduate School (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University in Saint Louis School of Medicine Oct 01 2015

United States

Assistant Professor :: Medicine; Division of Genomics & Bioinformatics

University of Michigan Jan 03 2011 - Sep 15 2015

United States

Postdoctoral Research Fellow :: Biostatistics

Education History

Emory University Laney Graduate School

United States

PHD :: Human Genetics

Publications

Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature 631 (8021) (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature 631 (8021) (2024)
Michael E Dunn, Aaron Kithcart, Jee Hae Kim, Andre Jo-Hao Ho, Matthew C Franklin, Annabel Romero Hernandez, Jan de Hoon, Wouter Botermans, Jonathan Meyer, Ximei Jin, Dongqin Zhang, Justin Torello, Daniel Jasewicz, Vishal Kamat, Elena Garnova, Nina Liu, Michael Rosconi, Hao Pan, Satyajit Karnik, Michael E Burczynski, Wenjun Zheng, Ashique Rafique, Jonas B Nielsen, Tanima De, Niek Verweij, Anita Pandit, Adam E Locke, Naga Chalasani, Olle Melander, Tae-Hwi Schwantes-An, null null, Aris Baras, Luca A Lotta, Bret J Musser, Jason Mastaitis, Kishor B Devalaraja-Narashimha, Andrew J Rankin, Tammy Huang, Gary Herman, William Olson, Andrew J Murphy, George D Yancopoulos, Benjamin A Olenchock, Lori Morton
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone. Nature (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature 631 (8021) (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature 631 (8021) (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature (2024)
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor, Joshua D Backman, Tyler Joseph, Evan Maxwell, George Mitra, Alexander Gorovits, Adam Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, Anthony Marcketta, Adam E Locke, Liron Ganel, Alicia Hawes, Michael D Kessler, Deepika Sharma, Jeffrey Staples, Jonas Bovijn, Sahar Gelfman, Alessandro Di Gioia, Veera Manikandan Rajagopal, Alexander Lopez, Jennifer Rico Varela, Jesus Alegre, Jaime Berumen-Campos, Roberto Tapia-Conyer, Pablo Kuri-Morales, Jason M Torres, Jonathan R Emberson, Rory Collins, null null, null null, Michael N Cantor, Timothy A Thornton, Hyun Min Kang, John D Overton, Alan R Shuldiner, M Laura Cremona, Mona Nafde, Aris Baras, Gonçalo R Abecasis, Jonathan Marchini, Jeffrey G Reid, William J Salerno, Suganthi Balasubramanian
A deep catalogue of protein-coding variation in 983,578 individuals. Nature 631 (8021) (2024)
Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li, Kyoko Watanabe, Anthony Marketta, Michael Van Meter, Stefan Semrau, Julie Horowitz, Jing Tang, Jack A Kosmicki, Veera M Rajagopal, Yuxin Zou, Yariv Houvras, Arkopravo Ghosh, Christopher Gillies, Joelle Mbatchou, Ryan R White, Niek Verweij, Jonas Bovijn, Neelroop N Parikshak, Michelle G LeBlanc, Marcus Jones, null null, null null, David J Glass, Luca A Lotta, Michael N Cantor, Gurinder S Atwal, Adam E Locke, Manuel A R Ferreira, Raquel Deering, Charles Paulding, Alan R Shuldiner, Gavin Thurston, Adolfo A Ferrando, Will Salerno, Jeffrey G Reid, John D Overton, Jonathan Marchini, Hyun M Kang, Aris Baras, Gonçalo R Abecasis, Eric Jorgensen
Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes. Nature (2023)
Tanmoy Roychowdhury, Derek M Klarin, Michael G Levin, Joshua M Spin, Yae Hyun Rhee, Alicia Deng, Colwyn A Headley, Noah L Tsao, Corry Gellatly, Verena Zuber, Fred Shen, Whitney E Hornsby, Ina Holst Laursen, Shefali Setia Verma, Adam E Locke, Gudmundur Einarsson, Gudmar Thorleifsson, Sarah E Graham, Ozan Dikilitas, Jack W Pattee, Renae L Judy, Ferran Pauls-Verges, Jonas B Nielsen, Brooke N Wolford, Ben Michael Brumpton, Jaime Dilme, Olga Peypoch, Laura Calsina Juscafresa, Todd L Edwards, Dadong Li, Karina Banasik, Soren Brunak, Rikke Louise Jacobsen, Minerva T Garcia-Barrio, Jifeng Zhang, Lars M Rasmussen, Regent Lee, Ashok Handa, Anders Wanhainen, Kevin Mani, Jes S Lindholt, Lasse Mollegaard Obel, Ewa Strauss, Grzegorz Oszkinis, Christopher P Nelson, Katie L Saxby, Joost A Van Herwaarden, Sander W van der Laan, Jessica van Setten, Mercedes Camacho, Frank M Davis, Rachael Wasikowski, Lam C Tsoi, Johann E Gudjonsson, Jonathan L Eliason, Dawn M Coleman, Peter K Henke, Santhi K Ganesh, Y Eugene Chen, Weihua Guan, James S Pankow, Nathan D Pankratz, Ole Birger Vesterager Pedersen, Christian Erikstrup, Weihong Tang, Kristian Hveem, Daníel F Guðbjartsson, Solveig Gretarsdottir, Unnur Thorsteinsdottir, Hilma Hólm, Kári Stefánsson, Manuel A R Ferreira, Aris Baras, Iftikhar J Kullo, Marylyn DeRiggi Ritchie, Alex H Christensen, Kasper K Iversen, Nikolaj Eldrup, Henrik Sillesen, Sisse Rye Ostrowski, Henning Bundgaard, Henrik Ullum, Stephen Burgess, Dipender Gill, Katherine Gallagher, Maria Sabater-Lleal, null null, null null, null null, null null, null null, Ida Surakka, Gregory T Jones, Matthew J Bown, Philip S Tsao, Cristen J Willer, Scott M Damrauer
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nature genetics (2023)
Eva König, Johannes Rainer, Vinicius Verri Hernandes, Giuseppe Paglia, Fabiola Del Greco M, Daniele Bottigliengo, Xianyong Yin, Lap Sum Chan, Alexander Teumer, Peter Paul Pramstaller, Adam E Locke, Christian Fuchsberger
Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort. Metabolites 12 (7) (2022)
Marijana Vujkovic, Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J Cordell, Jing He, Yevgeniy Gindin, Chuhan Chung, Robert P Myers, Carolin V Schneider, Joseph Park, Kyung Min Lee, Marina Serper, Rotonya M Carr, David E Kaplan, Mary E Haas, Matthew T MacLean, Walter R Witschey, Xiang Zhu, Catherine Tcheandjieu, Rachel L Kember, Henry R Kranzler, Anurag Verma, Ayush Giri, Derek M Klarin, Yan V Sun, Jie Huang, Jennifer E Huffman, Kate Townsend Creasy, Nicholas J Hand, Ching-Ti Liu, Michelle T Long, Jie Yao, Matthew J Budoff, Jingyi Tan, Xiaohui Li, Henry J Lin, Yii-Der Ida Chen, Kent D Taylor, Ruey-Kang Chang, Ronald M Krauss, Silvia Vilarinho, Joseph Brancale, Jonas B Nielsen, Adam E Locke, Marcus B Jones, Niek Verweij, Aris Baras, K Rajender Reddy, Brent A Neuschwander-Tetri, Jeffrey B Schwimmer, Arun J Sanyal, Naga Chalasani, Kathleen A Ryan, Braxton D Mitchell, Dipender Gill, Andrew D Wells, Elisabetta Manduchi, Yedidya Saiman, Nadim Mahmud, Donald R Miller, Peter D Reaven, Lawrence S Phillips, Sumitra Muralidhar, Scott L Duvall, Jennifer S Lee, Themistocles L Assimes, Saiju Pyarajan, Kelly Cho, Todd L Edwards, Scott M Damrauer, Peter W Wilson, J Michael Gaziano, Christopher J O'Donnell, Amit V Khera, Struan F A Grant, Christopher D Brown, Philip S Tsao, Danish Saleheen, Luca A Lotta, Lisa Bastarache, Quentin M Anstee, Ann K Daly, James B Meigs, Jerome I Rotter, Julie A Lynch, null null, null null, null null, null null, Daniel James Rader, Benjamin F Voight, Kyong-Mi Chang
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. Nature genetics 54 (6) (2022)
Julie E Horowitz, Jack A Kosmicki, Amy Damask, Deepika Sharma, Genevieve H L Roberts, Anne E Justice, Nilanjana Banerjee, Marie V Coignet, Ashish Yadav, Joseph B Leader, Anthony Marcketta, Danny S Park, Rouel Lanche, Evan Maxwell, Spencer C Knight, Xiaodong Bai, Harendra Guturu, Dylan Sun, Asher Baltzell, Fabricio S P Kury, Joshua D Backman, Ahna R Girshick, Colm O'Dushlaine, Shannon R McCurdy, Raghavendran Partha, Adam J Mansfield, David A Turissini, Alexander H Li, Miao Zhang, Joelle Mbatchou, Kyoko Watanabe, Lauren Gurski, Shane E McCarthy, Hyun M Kang, Lee Dobbyn, Eli Stahl, Anurag Verma, Giorgio Sirugo, null null, Marylyn DeRiggi Ritchie, Marcus Jones, Suganthi Balasubramanian, Katherine Siminovitch, William J Salerno, Alan R Shuldiner, Daniel James Rader, Tooraj Mirshahi, Adam E Locke, Jonathan Marchini, John D Overton, David J Carey, Lukas Habegger, Michael N Cantor, Kristin A Rand, Eurie L Hong, Jeffrey G Reid, Catherine A Ball, Aris Baras, Gonçalo R Abecasis, Manuel A R Ferreira
Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease. Nature genetics 54 (4) (2022)
Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li, Kyoko Watanabe, Anthony Marketta, Michael Van Meter, Stefan Semrau, Julie Horowitz, Jing Tang, Jack A Kosmicki, Veera M Rajagopal, Yuxin Zou, Yariv Houvras, Arkopravo Ghosh, Christopher Gillies, Joelle Mbatchou, Ryan R White, Niek Verweij, Jonas Bovijn, Neelroop N Parikshak, Michelle G LeBlanc, Marcus Jones, null null, null null, David J Glass, Luca A Lotta, Michael N Cantor, Gurinder S Atwal, Adam E Locke, Manuel A R Ferreira, Raquel Deering, Charles Paulding, Alan R Shuldiner, Gavin Thurston, Adolfo A Ferrando, Will Salerno, Jeffrey G Reid, John D Overton, Jonathan Marchini, Hyun M Kang, Aris Baras, Gonçalo R Abecasis, Eric Jorgensen
Common and rare variant associations with clonal haematopoiesis phenotypes. Nature 612 (7939) (2022)
Parsa Akbari, Olukayode A Sosina, Jonas Bovijn, Karl Landheer, Jonas B Nielsen, Minhee Kim, Senem Aykul, Tanima De, Mary E Haas, George Hindy, Nan Lin, Ian R Dinsmore, Jonathan Z Luo, Stefanie Hectors, Benjamin Geraghty, Mary Germino, Lampros Panagis, Prodromos Parasoglou, Johnathon R Walls, Gabor Halasz, Gurinder S Atwal, null null, null null, Marcus Jones, Michelle G LeBlanc, Christopher D Still, David J Carey, Alice Giontella, Marju Orho-Melander, Jaime Berumen-Campos, Pablo Kuri-Morales, Jesus Alegre, Jason M Torres, Jonathan R Emberson, Rory Collins, Daniel James Rader, Brian Zambrowicz, Andrew J Murphy, Suganthi Balasubramanian, John D Overton, Jeffrey G Reid, Alan R Shuldiner, Michael Cantor, Gonçalo R Abecasis, Manuel A R Ferreira, Mark W Sleeman, Viktoria Gusarova, Judith Altarejos, Charles Harris, Aris N Economides, Vincent Idone, Katia Karalis, Giusy Della Gatta, Tooraj Mirshahi, George D Yancopoulos, Olle Melander, Jonathan Marchini, Roberto Tapia-Conyer, Adam E Locke, Aris Baras, Niek Verweij, Luca A Lotta
Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes. Nature communications 13 (1) (2022)
Xianyong Yin, Lap Sum Chan, Debraj Bose, Anne U Jackson, Peter VandeHaar, Adam E Locke, Christian Fuchsberger, Heather M Stringham, Ryan P Welch, Ketian Yu, Lilian Fernandes Silva, Susan K Service, Daiwei Zhang, Emily C Hector, Erica P Young, Liron Ganel, Indraniel Das, Haley Abel, Michael R Erdos, Lori L Bonnycastle, Johanna Kuusisto, Nathan O Stitziel, Ira M Hall, Gregory R Wagner, null null, Jian Kang, Jean Morrison, Charles F Burant, Francis S Collins, Samuli Ripatti, Aarno Palotie, Nelson A Freimer, Karen L Mohlke, Laura J Scott, Xiaoquan Wen, Eric B Fauman, Markku Laakso, Michael Boehnke
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci. Nature communications 13 (1) (2022)
Duncan S Palmer, Daniel P Howrigan, Sinéad B Chapman, Rolf Adolfsson, Nick Bass, Douglas H R Blackwood, Marco P M Boks, Chia-Yen Chen, Claire Churchhouse, Aiden P Corvin, Nicholas Craddock, David Curtis, Arianna Di Florio, Faith Dickerson, Nelson A Freimer, Fernando S Goes, Xiaoming Jia, Ian R Jones, Lisa A Jones, Lina Jonsson, Rene S Kahn, Mikaél Landén, Adam E Locke, Andrew M McIntosh, Andrew McQuillin, Derek W Morris, Michael C O'Donovan, Roel A Ophoff, Michael J Owen, Nancy L Pedersen, Danielle Posthuma, Andreas Reif, Neil Risch, Catherine Schaefer, Laura J Scott, Tarjinder Singh, Jordan W Smoller, Matthew Solomonson, David St Clair, Eli A Stahl, Annabel Vreeker, James T R Walters, Weiqing Wang, Nicholas A Watts, Robert Yolken, Peter P Zandi, Benjamin M Neale
Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia. Nature genetics 54 (5) (2022)
Joshua D Backman, Alexander H Li, Anthony Marcketta, Dylan Sun, Joelle Mbatchou, Michael D Kessler, Christian Benner, Daren Liu, Adam E Locke, Suganthi Balasubramanian, Ashish Yadav, Nilanjana Banerjee, Christopher E Gillies, Amy Damask, Simon Liu, Xiaodong Bai, Alicia Hawes, Evan Maxwell, Lauren Gurski, Kyoko Watanabe, Jack A Kosmicki, Veera Rajagopal, Jason Mighty, null null, null null, Marcus Jones, Lyndon Mitnaul, Eli Stahl, Giovanni Coppola, Eric Jorgensen, Lukas Habegger, William J Salerno, Alan R Shuldiner, Luca A Lotta, John D Overton, Michael N Cantor, Jeffrey G Reid, George Yancopoulos, Hyun M Kang, Jonathan Marchini, Aris Baras, Gonçalo R Abecasis, Manuel A R Ferreira
Exome sequencing and analysis of 454,787 UK Biobank participants. Nature 599 (7886) (2021)
Julia T Warren, Ryan R Cupo, Peeradol Wattanasirakul, David H Spencer, Adam E Locke, Vahagn Makaryan, Audrey Anna Bolyard, Meredith L Kelley, Natalie L Kingston, James Shorter, Christine Bellanné-Chantelot, Jean Donadieu, David C Dale, Daniel C Link
Heterozygous Variants of CLPB are a Cause of Severe Congenital Neutropenia. Blood (2021)
May E Montasser, Cristopher V Van Hout, Lawrence Miloscio, Alicia D Howard, Avraham Rosenberg, Myrasol Callaway, Biao Shen, Ning Li, Adam E Locke, Niek Verweij, Tanima De, Manuel A R Ferreira, Luca A Lotta, Aris Baras, Thomas J Daly, Suzanne A Hartford, Wei Lin, Yuan Mao, Bin Ye, Derek White, Guochun Gong, James A Perry, Kathleen A Ryan, Qing Fang, Gannie Tzoneva, Evangelos Pefanis, Charleen Hunt, Yajun Tang, Lynn Lee, null null, Carole Sztalryd-Woodle, Braxton D Mitchell, Matthew Healy, Elizabeth A Streeten, Simeon I Taylor, Jeffrey R O'Connell, Aris N Economides, Giusy Della Gatta, Alan R Shuldiner
Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen. Science (New York, N.Y.) 374 (6572) (2021)
Xiaoming Jia, Fernando S Goes, Adam E Locke, Duncan S Palmer, Weiqing Wang, Sarah Cohen-Woods, Giulio Genovese, Anne U Jackson, Chen Jiang, Mark Kvale, Niamh Mullins, Tan-Hoang Nguyen, Mehdi Pirooznia, Margarita Rivera, Douglas M Ruderfer, Ling Shen, Khanh Thai, Matthew Zawistowski, Yongwen Zhuang, Gonçalo R Abecasis, Huda Akil, Sarah E Bergen, Margit Burmeister, Sinéad Chapman, Melissa DelaBastide, Anders Juréus, Hyun Min Kang, Pui-Yan Kwok, Jun Z Li, Shawn E Levy, Eric T Monson, Jennifer Moran, Janet Sobell, Stanley J Watson, Virginia Willour, Sebastian Zöllner, Rolf Adolfsson, Douglas H R Blackwood, Michael Boehnke, Gerome D Breen, Aiden Corvin, Nick Craddock, Arianna DiFlorio, Christina M Hultman, Mikaél Landén, Cathryn M Lewis, Steven A McCarroll, W Richard McCombie, Peter McGuffin, Andrew M McIntosh, Andrew McQuillin, Derek W Morris, Richard M Myers, Michael C O'Donovan, Roel Ophoff, Marco P M Boks, Rene S Kahn, Willem Hendrik Ouwehand, Michael J Owen, Carlos Pato, Michele Pato, Danielle Posthuma, James B Potash, Andreas Reif, Pamela Sklar, Jordan Smoller, Patrick F Sullivan, John B Vincent, James Walters, Benjamin M Neale, Shaun M Purcell, Neil Risch, Catherine Schaefer, Eli A Stahl, Peter P Zandi, Laura J Scott
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular psychiatry 26 (9) (2021)
Parsa Akbari, Ankit Gilani, Olukayode A Sosina, Jack A Kosmicki, Lori Khrimian, Yi-Ya Fang, Trikaldarshi Persaud, Victor Garcia, Dylan Sun, Alexander H Li, Joelle Mbatchou, Adam E Locke, Christian Benner, Niek Verweij, Nan Lin, Sakib Hossain, Kevin Agostinucci, Jonathan V Pascale, Ercument Dirice, Michael Dunn, null null, null null, William E Kraus, Svati H Shah, Yii-Der I Chen, Jerome I Rotter, Daniel James Rader, Olle Melander, Christopher D Still, Tooraj Mirshahi, David J Carey, Jaime Berumen-Campos, Pablo Kuri-Morales, Jesus Alegre, Jason M Torres, Jonathan R Emberson, Rory Collins, Suganthi Balasubramanian, Alicia Hawes, Marcus Jones, Brian Zambrowicz, Andrew J Murphy, Charles Paulding, Giovanni Coppola, John D Overton, Jeffrey G Reid, Alan R Shuldiner, Michael Cantor, Hyun-Min Kang, Goncalo R Abecasis, Katia Karalis, Aris N Economides, Jonathan Marchini, George D Yancopoulos, Mark W Sleeman, Judith Altarejos, Giusy Della Gatta, Roberto Tapia-Conyer, Michal L Schwartzman, Aris Baras, Manuel A R Ferreira, Luca A Lotta
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity. Science (New York, N.Y.) 373 (6550) (2021)
Cassandra N Spracklen, Apoorva K Iyengar, Swarooparani Vadlamudi, Chelsea K Raulerson, Anne U Jackson, Sarah M Brotman, Ying Wu, Maren E Cannon, James P Davis, Aaron T Crain, Kevin W Currin, Hannah J Perrin, Narisu Narisu, Heather M Stringham, Christian Fuchsberger, Adam E Locke, Ryan P Welch, Johanna K Kuusisto, Päivi Pajukanta, Laura J Scott, Yun Li, Francis S Collins, Michael Boehnke, Markku Laakso, Karen L Mohlke
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. PLoS genetics 16 (9) (2020)
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Goo Jun, Alisa Manning, Marcio Almeida, Matthew Zawistowski, Andrew R Wood, Tanya M Teslovich, Christian Fuchsberger, Shuang Feng, Pablo Cingolani, Kyle J Gaulton, Thomas Dyer, Thomas W Blackwell, Han Chen, Peter S Chines, Sungkyoung Choi, Claire Churchhouse, Pierre Fontanillas, Ryan King, SungYoung Lee, Stephen E Lincoln, Vasily Trubetskoy, Mark DePristo, Tasha Fingerlin, Robert Grossman, Jason Grundstad, Alison Heath, Jayoun Kim, Young Jin Kim, Jason Laramie, Jaehoon Lee, Heng Li, Xuanyao Liu, Oren Livne, Adam E Locke, Julian Maller, Alexander Mazur, Andrew P Morris, Toni I Pollin, Derek Ragona, David Reich, Manuel A Rivas, Laura J Scott, Xueling Sim, Rick G Tearle, Yik Ying Teo, Amy L Williams, Sebastian Zöllner, Joanne E Curran, Juan Peralta, Beena Akolkar, Graeme I Bell, Noël P Burtt, Nancy J Cox, Jose C Florez, Craig L Hanis, Catherine McKeon, Karen L Mohlke, Mark Seielstad, James G Wilson, Gil Atzmon, Jennifer E Below, Josée Dupuis, Dan L Nicolae, Donna Lehman, Taesung Park, Sungho Won, Robert Sladek, David Altshuler, Mark I McCarthy, Ravindranath Duggirala, Michael Boehnke, Timothy M Frayling, Gonçalo R Abecasis, John Blangero
Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proceedings of the National Academy of Sciences of the United States of America 115 (2) (2017)
Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M Teslovich, Vineeta Agarwala, Kyle J Gaulton, Lizz Caulkins, Ryan Koesterer, Clement Ma, Loukas Moutsianas, Davis J McCarthy, Manuel A Rivas, John R B Perry, Xueling Sim, Thomas W Blackwell, Neil R Robertson, N William Rayner, Pablo Cingolani, Adam E Locke, Juan Fernandez Tajes, Heather M Highland, Josee Dupuis, Peter S Chines, Cecilia M Lindgren, Christopher Hartl, Anne U Jackson, Han Chen, Jeroen R Huyghe, Martijn van de Bunt, Richard D Pearson, Ashish Kumar, Martin Hrabě de Angelis, Niels Grarup, Heather M Stringham, Eric R Gamazon, Jaehoon Lee, Yuhui Chen, Robert A Scott, Jennifer E Below, Peng Chen, Jinyan Huang, Min Jin Go, Michael L Stitzel, Dorota Pasko, Stephen C J Parker, Tibor V Varga, Todd Green, Nicola L Beer, Aaron G Day-Williams, Teresa Ferreira, Tasha Fingerlin, Momoko Horikoshi, Cheng Hu, Iksoo Huh, Mohammad Kamran Ikram, Bong-Jo Kim, Yongkang Kim, Young Jin Kim, Min-Seok Kwon, Juyoung Lee, Selyeong Lee, Keng-Han Lin, Taylor J Maxwell, Yoshihiko Nagai, Xu Wang, Ryan P Welch, Joon Yoon, Weihua Zhang, Nir Barzilai, Benjamin F Voight, Bok-Ghee Han, Christopher P Jenkinson, Teemu Kuulasmaa, Johanna Kuusisto, Alisa Manning, Maggie C Y Ng, Nicholette D Palmer, Beverley Balkau, Alena Stančáková, Hanna E Abboud, Heiner Boeing, Vilmantas Giedraitis, Dorairaj Prabhakaran, Omri Gottesman, James Scott, Jason Carey, Phoenix Kwan, George Grant, Joshua D Smith, Benjamin M Neale, Shaun Purcell, Adam S Butterworth, Joanna M M Howson, Heung Man Lee, Yingchang Lu, Soo-Heon Kwak, Wei Zhao, John Danesh, Vincent K L Lam, Kyong-Soo Park, Danish Saleheen, Wing Yee So, Claudia H T Tam, Uzma Afzal, David Aguilar, Rector Arya, Tin Aung, Edmund Chan, Carmen Navarro, Ching-Yu Cheng, Domenico Palli, Adolfo Correa, Joanne E Curran, Dennis Rybin, Vidya S Farook, Sharon P Fowler, Barry I Freedman, Michael Griswold, Daniel Esten Hale, Pamela J Hicks, Chiea Chuen Khor, Satish Kumar, Benjamin Lehne, Dorothée Thuillier, Wei Yen Lim, Jianjun Liu, Marie Loh, Solomon K Musani, Sobha Puppala, William R Scott, Loïc Yengo, Sian-Tsung Tan, Herman A Taylor, Farook Thameem, Gregory Wilson, Tien Yin Wong, Pål Rasmus Njølstad, Jonathan C Levy, Massimo Mangino, Lori L Bonnycastle, Thomas Schwarzmayr, João Fadista, Gabriela L Surdulescu, Christian Herder, Christopher J Groves, Thomas Wieland, Jette Bork-Jensen, Ivan Brandslund, Cramer Christensen, Heikki A Koistinen, Alex S F Doney, Leena Kinnunen, Tõnu Esko, Andrew J Farmer, Liisa Hakaste, Dylan Hodgkiss, Jasmina Kravic, Valeri Lyssenko, Mette Hollensted, Marit E Jørgensen, Torben Jørgensen, Claes Ladenvall, Johanne Marie Justesen, Annemari Käräjämäki, Jennifer Kriebel, Wolfgang Rathmann, Lars Lannfelt, Torsten Lauritzen, Narisu Narisu, Allan Linneberg, Olle Melander, Lili A Milani, Matt Neville, Marju Orho-Melander, Lu Qi, Qibin Qi, Michael Roden, Olov Rolandsson, Amy Swift, Anders H Rosengren, Kathleen Stirrups, Andrew R Wood, Evelin Mihailov, Christine Blancher, Mauricio O Carneiro, Jared Maguire, Ryan Poplin, Khalid Shakir, Timothy Fennell, Mark DePristo, Martin Hrabé de Angelis, Panagiotis Deloukas, Anette P Gjesing, Goo Jun, Peter Nilsson, Jacquelyn Murphy, Robert Onofrio, Barbara Thorand, Torben Hansen, Christa Meisinger, Frank B Hu, Bo Isomaa, Fredrik Karpe, Liming Liang, Annette Peters, Cornelia Huth, Stephen P O'Rahilly, Colin N A Palmer, Oluf Pedersen, Rainer Rauramaa, Tiinamaija Tuomi, Veikko Salomaa, Richard M Watanabe, Ann-Christine Syvänen, Richard N Bergman, Dwaipayan Bharadwaj, Erwin P Bottinger, Yoon Shin Cho, Giriraj R Chandak, Juliana Cn Chan, Kee Seng Chia, Mark J Daly, Shah B Ebrahim, Claudia Langenberg, Paul Elliott, Kathleen A Jablonski, Donna M Lehman, Weiping Jia, Ronald Ching-Wan Ma, Toni I Pollin, Manjinder Sandhu, Nikhil Tandon, Phillippe Froguel, Inês A Barroso, Yik Ying Teo, Eleftheria Zeggini, Ruth J F Loos, Kerrin S Small, Janina S Ried, Ralph A DeFronzo, Harald Grallert, Benjamin Glaser, Andres Metspalu, Nicholas J Wareham, Mark Walker, Eric Banks, Christian Gieger, Erik Ingelsson, Hae Kyung Im, Thomas Illig, Paul W Franks, Gemma Buck, Joseph Trakalo, David Buck, Inga Prokopenko, Reedik Mägi, Lars Lind, Yossi Farjoun, Katharine R Owen, Anna L Gloyn, Konstantin Strauch, Tiinamaija Tuomi, Jaspal Singh Kooner, Jong Young Lee, Taesung Park, Peter Donnelly, Andrew D Morris, Andrew T Hattersley, Donald W Bowden, Francis S Collins, Gil Atzmon, John C Chambers, Timothy D Spector, Markku Laakso, Tim M Strom, Graeme I Bell, John Blangero, Ravindranath Duggirala, E Shyong Tai, Gilean McVean, Craig L Hanis, James G Wilson, Mark Seielstad, Timothy M Frayling, James B Meigs, Nancy J Cox, Rob Sladek, Eric S Lander, Stacey Gabriel, Karen L Mohlke, Thomas Meitinger, Leif C Groop, Goncalo Abecasis, Laura J Scott, Andrew P Morris, Hyun Min Kang, David Altshuler, Noël P Burtt, Jose C Florez, Michael Boehnke, Mark I McCarthy
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific data 4 (2017)
Dhanya Ramachandran, Jennifer G Mulle, Adam E Locke, Lora J H Bean, Tracie C Rosser, Promita Bose, Kenneth J Dooley, Clifford L Cua, George T Capone, Kenneth J Dooley, Clifford L Cua, David J Cutler, Stephanie L Sherman, Michael E Zwick
Contribution of copy-number variation to Down syndrome-associated atrioventricular septal defects. Genetics in medicine : official journal of the American College of Medical Genetics 17 (7) (2014)

Adam E Locke.css-eqlu8i{font-size:small;padding-left:4px;} (Adam Locke)

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Adam E Locke (Adam Locke)