Constantinos Koumenis (Costas Koumenis)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Venues

Molecular cancer research : MCR

Molecular cancer therapeutics

Oncoimmunology

Science advances

University of Pennsylvania Perelman School of Medicine

University of Houston (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania Perelman School of Medicine

United States

co-Leader Radiation Oncology Translational Center of Excellence :: Abramson Cancer Center

University of Pennsylvania Perelman School of Medicine

United States

Richard H. Chamberlain Professor with Tenure :: Department of Radiation Oncology

University of Pennsylvania Perelman School of Medicine

United States

Vice Chair & Research Division Director :: Department of Radiation Oncology

University of Pennsylvania Perelman School of Medicine

United States

co-Leader Radiobiology and Imaging Program (RBI) :: Abramson Cancer Center

University of Pennsylvania Perelman School of Medicine

United States

Professor with Tenure :: Department of Radiation Oncology

University of Pennsylvania Perelman School of Medicine

United States

Associate Professor with Tenure :: Department of Radiation Oncology

Wake Forest University School of Medicine

United States

Associate Professor :: Department of Radiation Oncology

Wake Forest University School of Medicine

United States

Associate Professor :: Department of Neurosurgery

Wake Forest School of Medicine

United States

Associate Member :: Department of Cancer Biology

Wake Forest University School of Medicine

United States

Assistant Professor :: Department of Radiation Oncology

Stanford University School of Medicine

United States

Postdoctoral Fellow :: Department of Radiation Oncology

Education History

University of Houston

United States

PHD :: Biochemistry and Biophysics Sciences

Aristotle University of Thessaloniki

Greece

BSC

Publications

Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I Verginadis, George Morcos, Phoebe E Loo, Michele M Kim, Seyyedeh Azar Oliaei Motlagh, Khayrullo Shoniyozov, Eric S Diffenderfer, Emilio A Ocampo, Mary E Putt, Charles-Antoine Assenmacher, Enrico Radaelli, Jiawei Lu, Ling Qin, Hengxi Liu, Nektaria Maria Leli, Swati Girdhani, Nicolas Denef, Francois Vander Stappen, Keith A Cengel, Theresa M Busch, James M Metz, Lei Dong, Alexander Lin, Constantinos Koumenis
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer. Molecular cancer therapeutics 23 (6) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR 22 (4) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR 22 (4) (2024)
Nektarios Kostopoulos, Francesca Costabile, Elisavet Krimitza, Silvia Beghi, Denisa Goia, Renzo Perales-Linares, George Thyfronitis, Michael J LaRiviere, Elise A Chong, Stephen J Schuster, Amit Maity, Constantinos Koumenis, John P Plastaras, Andrea Facciabene
Local Radiation Enhances Systemic CAR T Cell Efficacy by Augmenting Antigen Cross-Presentation and T-cell Infiltration. Blood advances (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR (2024)
Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I Verginadis, George Morcos, Phoebe E Loo, Michele M Kim, Seyyedeh Azar Oliaei Motlagh, Khayrullo Shoniyozov, Eric S Diffenderfer, Emilio A Ocampo, Mary E Putt, Charles-Antoine Assenmacher, Enrico Radaelli, Jiawei Lu, Ling Qin, Hengxi Liu, Nektaria Maria Leli, Swati Girdhani, Nicolas Denef, Francois Vander Stappen, Keith A Cengel, Theresa M Busch, James M Metz, Lei Dong, Alexander Lin, Constantinos Koumenis
Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer. Molecular cancer therapeutics (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I Verginadis, George Morcos, Phoebe E Loo, Michele M Kim, Seyyedeh Azar Oliaei Motlagh, Khayrullo Shoniyozov, Eric S Diffenderfer, Emilio A Ocampo, Mary E Putt, Charles-Antoine Assenmacher, Enrico Radaelli, Jiawei Lu, Ling Qin, Hengxi Liu, Nektaria Maria Leli, Swati Girdhani, Nicolas Denef, Francois Vander Stappen, Keith A Cengel, Theresa M Busch, James M Metz, Lei Dong, Alexander Lin, Constantinos Koumenis
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer. Molecular cancer therapeutics 23 (6) (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR 22 (4) (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR (2024)
Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I Verginadis, George Morcos, Phoebe E Loo, Michele M Kim, Seyyedeh Azar Oliaei Motlagh, Khayrullo Shoniyozov, Eric S Diffenderfer, Emilio A Ocampo, Mary E Putt, Charles-Antoine Assenmacher, Enrico Radaelli, Jiawei Lu, Ling Qin, Hengxi Liu, Nektaria Maria Leli, Swati Girdhani, Nicolas Denef, Francois Vander Stappen, Keith A Cengel, Theresa M Busch, James M Metz, Lei Dong, Alexander Lin, Constantinos Koumenis
Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer. Molecular cancer therapeutics (2024)
Zhen Lu, Ioannis I Verginadis, Motofumi Kumazoe, Gerardo M Castillo, Yao Yao, Rebecca E Guerra, Sandra Bicher, Menghao You, George McClung, Rong Qiu, Zebin Xiao, Zhen Miao, Subin S George, Daniel P Beiting, Takashi Nojiri, Yasutake Tanaka, Yoshinori Fujimura, Hiroaki Onda, Yui Hatakeyama, Akiko Nishimoto-Ashfield, Katrina Bykova, Wei Guo, Yi Fan, Nikolay M Buynov, J Alan Diehl, Ben Z Stanger, Hirofumi Tachibana, Terence P F Gade, Ellen Puré, Constantinos Koumenis, Elijah M Bolotin, Serge Y Fuchs
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies. Science translational medicine 16 (761) (2024)
Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I Verginadis, George Morcos, Phoebe E Loo, Michele M Kim, Seyyedeh Azar Oliaei Motlagh, Khayrullo Shoniyozov, Eric S Diffenderfer, Emilio A Ocampo, Mary E Putt, Charles-Antoine Assenmacher, Enrico Radaelli, Jiawei Lu, Ling Qin, Hengxi Liu, Nektaria Maria Leli, Swati Girdhani, Nicolas Denef, Francois Vander Stappen, Keith A Cengel, Theresa M Busch, James M Metz, Lei Dong, Alexander Lin, Constantinos Koumenis
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer. Molecular cancer therapeutics 23 (6) (2024)
Renzo Perales-Linares, Nektaria Maria Leli, Hesham Mohei, Silvia Beghi, Osvaldo D Rivera, Nektarios Kostopoulos, Andrea Giglio, Subin S George, Mireia Uribe-Herranz, Francesca Costabile, Stefano Pierini, Sergei Pustylnikov, Giorgos Skoufos, Yoseph Barash, Artemis G Hatzigeorgiou, Constantinos Koumenis, Amit Maity, Michael T Lotze, Andrea Facciabene
Parkin deficiency suppresses antigen presentation to promote tumor immune evasion and immunotherapy resistance. Cancer research (2023)
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L Guzman, Kevin J Harrington, Fernanda G Herrera, Jamie Honeychurch, Theodore S Hong, Lorea Iturri, Elisabeth Jaffee, Sana D Karam, Simon R V Knott, Constantinos Koumenis, David C Lyden, Ariel E Marciscano, Alan A Melcher, Michele Mondini, Anna Mondino, Zachary S Morris, Sean P Pitroda, Sergio A Quezada, Laura Santambrogio, Stephen L Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph R Weichselbaum, James Welsh, Anna C Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Sylvia C Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6 th annual ImmunoRad conference. Oncoimmunology 12 (1) (2023)
Nektaria Maria Leli, Constantinos Koumenis
A Novel Ubiquitin Complex Regulates Aneuploid Epithelial Tumors by Moderating an Integrated Stress Response. Cancer discovery 13 (3) (2023)
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L Guzman, Kevin J Harrington, Fernanda G Herrera, Jamie Honeychurch, Theodore S Hong, Lorea Iturri, Elisabeth Jaffee, Sana D Karam, Simon R V Knott, Constantinos Koumenis, David C Lyden, Ariel E Marciscano, Alan A Melcher, Michele Mondini, Anna Mondino, Zachary S Morris, Sean P Pitroda, Sergio A Quezada, Laura Santambrogio, Stephen L Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph R Weichselbaum, James Welsh, Anna C Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Sylvia C Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6 th annual ImmunoRad conference. Oncoimmunology 12 (1) (2023)
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L Guzman, Kevin J Harrington, Fernanda G Herrera, Jamie Honeychurch, Theodore S Hong, Lorea Iturri, Elisabeth Jaffee, Sana D Karam, Simon R V Knott, Constantinos Koumenis, David C Lyden, Ariel E Marciscano, Alan A Melcher, Michele Mondini, Anna Mondino, Zachary S Morris, Sean P Pitroda, Sergio A Quezada, Laura Santambrogio, Stephen L Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph R Weichselbaum, James Welsh, Anna C Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Sylvia C Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6 th annual ImmunoRad conference. Oncoimmunology 12 (1) (2023)
Zacharenia Nikitaki, Anastasia Velalopoulou, Vassiliki Zanni, Ioanna Tremi, Sophia Havaki, Michael Kokkoris, Vassilis G Gorgoulis, Constantinos Koumenis, Alexandros G Georgakilas
Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair. Expert reviews in molecular medicine 24 (2022)
Amit Maity, Constantinos Koumenis
Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Ioannis I Verginadis, Harris Avgousti, James Monslow, Giorgos Skoufos, Frank Chinga, Kyle Kim, Nektaria Maria Leli, Ilias V Karagounis, Brett I Bell, Anastasia Velalopoulou, Carlo Salas Salinas, Victoria S Wu, Yang Li, Jiangbin Ye, David A Scott, Andrei L Osterman, Arjun Sengupta, Aalim Weljie, Menggui Huang, Duo Zhang, Yi Fan, Enrico Radaelli, John W Tobias, Florian Rambow, Panagiotis Karras, Jean-Christophe Marine, Xiaowei Xu, Artemis G Hatzigeorgiou, Sandra W Ryeom, J Alan Diehl, Serge Y Fuchs, Ellen Puré, Constantinos Koumenis
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Nature cell biology 24 (6) (2022)
Menggui Huang, Duo Zhang, Janet Y Wu, Kun Xing, Eujin Yeo, Chunsheng Li, Lin Zhang, Eric C Holland, Lutian Yao, Ling Qin, Zev A Binder, Donald M O'Rourke, Steven Brem, Constantinos Koumenis, Yanqing Gong, Yi Fan
Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma. Science translational medicine 12 (532) (2021)
Anastasia Velalopoulou, Ilias V Karagounis, Gwendolyn M Cramer, Michele M Kim, Giorgos Skoufos, Denisa Goia, Sarah Hagan, Ioannis I Verginadis, Khayrullo Shoniyozov, June Chiango, Michelle Cerullo, Kelley Varner, Lutian Yao, Ling Qin, Artemis G Hatzigeorgiou, Andy J Minn, Mary Putt, Matthew Lanza, Charles-Antoine Assenmacher, Enrico Radaelli, Jennifer Huck, Eric S Diffenderfer, Lei Dong, James Metz, Constantinos Koumenis, Keith A Cengel, Amit Maity, Theresa M Busch
FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response. Cancer research 81 (18) (2021)
Christoforos Thomas, Ilias V Karagounis, Ratnesh K Srivastava, Nicholas Vrettos, Fotis Nikolos, Noëlle Francois, Menggui Huang, Siliang Gong, Qi Long, Sushil Kumar, Constantinos Koumenis, Savitri Krishnamurthy, Naoto Tada Ueno, Rumela Chakrabarti, Amit Maity
Estrogen Receptor β-Mediated Inhibition of Actin-Based Cell Migration Suppresses Metastasis of Inflammatory Breast Cancer. Cancer research 81 (9) (2021)
Alexandra D Dreyfuss, Denisa Goia, Khayrullo Shoniyozov, Swapnil V Shewale, Anastasia Velalopoulou, Susan Mazzoni, Harris Avgousti, Scott D Metzler, Paco E Bravo, Steven J Feigenberg, Bonnie Ky, Ioannis I Verginadis, Constantinos Koumenis
A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (8) (2021)
Feven Tameire, Ioannis I Verginadis, Nektaria Maria Leli, Christine Polte, Crystal S Conn, Rani Ojha, Carlo Salas Salinas, Frank Chinga, Alexandra M Monroy, Weixuan Fu, Zhiping Wang, Andrew Kossenkov, Jiangbin Ye, Ravi K Amaravadi, Zoya Ignatova, Serge Y Fuchs, J Alan Diehl, Davide Ruggero, Constantinos Koumenis
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature cell biology 21 (7) (2019)
Hao G Nguyen, Crystal S Conn, Yae Kye, Lingru Xue, Craig M Forester, Janet E Cowan, Andrew C Hsieh, John T Cunningham, Charles Truillet, Feven Tameire, Kenneth W Bayles, Christopher P Evans, Joy C Yang, Byron C Hann, Constantinos Koumenis, Peter Walter, Peter R Carroll, Davide Ruggero
Development of a stress response therapy targeting aggressive prostate cancer. Science translational medicine 10 (439) (2019)
Lauren K Brady, Hejia Wang, Caleb M Radens, Yue Bi, Milan Radovich, Amit Maity, Cristina Ivan, Mircea Ivan, Yoseph Barash, Constantinos Koumenis
Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation. PLoS biology 15 (9) (2017)

Constantinos Koumenis.css-eqlu8i{font-size:small;padding-left:4px;} (Costas Koumenis)

Publication Activity (10 Years)

Top Topics

Top Venues

Constantinos Koumenis (Costas Koumenis)