Alan F Cowman

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 22

Top Topics

Plasmodium Falciparum

Structural Basis

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Nature microbiology

This page only lists publications with an associated author ORCID identifier.

Publications

Madeline G Dans, Coralie Boulet, Gabrielle M Watson, William Nguyen, Jerzy M Dziekan, Cindy Evelyn, Kitsanapong Reaksudsan, Somya Mehra, Zahra Razook, Niall D Geoghegan, Michael J Mlodzianoski, Christopher Dean Goodman, Dawson B Ling, Thorey K Jonsdottir, Joshua Tong, Mufuliat Toyin Famodimu, Mojca Kristan, Harry Pollard, Lindsay B Stewart, Luke Brandner-Garrod, Colin J Sutherland, Michael J Delves, Geoffrey I McFadden, Alyssa E Barry, Brendan S Crabb, Tania F de Koning-Ward, Kelly L Rogers, Alan F Cowman, Wai-Hong Tham, Robin B Gasser, Paul R Gilson
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1. Nature communications 15 (1) (2024)
Robyn McConville, Jelte M M Krol, Ryan W J Steel, Matthew T O'Neill, Bethany K Davey, Anthony N Hodder, Thomas Nebl, Alan F Cowman, Norman Kneteman, Justin A Boddey
Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development. Proceedings of the National Academy of Sciences of the United States of America 121 (28) (2024)
Robyn McConville, Jelte M M Krol, Ryan W J Steel, Matthew T O'Neill, Bethany K Davey, Anthony N Hodder, Thomas Nebl, Alan F Cowman, Norman Kneteman, Justin A Boddey
Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development. Proceedings of the National Academy of Sciences of the United States of America 121 (28) (2024)
Robyn McConville, Jelte M M Krol, Ryan W J Steel, Matthew T O'Neill, Bethany K Davey, Anthony N Hodder, Thomas Nebl, Alan F Cowman, Norman Kneteman, Justin A Boddey
Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development. Proceedings of the National Academy of Sciences of the United States of America 121 (28) (2024)
Madeline G Dans, Coralie Boulet, Gabrielle M Watson, William Nguyen, Jerzy M Dziekan, Cindy Evelyn, Kitsanapong Reaksudsan, Somya Mehra, Zahra Razook, Niall D Geoghegan, Michael J Mlodzianoski, Christopher Dean Goodman, Dawson B Ling, Thorey K Jonsdottir, Joshua Tong, Mufuliat Toyin Famodimu, Mojca Kristan, Harry Pollard, Lindsay B Stewart, Luke Brandner-Garrod, Colin J Sutherland, Michael J Delves, Geoffrey I McFadden, Alyssa E Barry, Brendan S Crabb, Tania F de Koning-Ward, Kelly L Rogers, Alan F Cowman, Wai-Hong Tham, Robin B Gasser, Paul R Gilson
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1. Nature communications 15 (1) (2024)
Madeline G Dans, Coralie Boulet, Gabrielle M Watson, William Nguyen, Jerzy M Dziekan, Cindy Evelyn, Kitsanapong Reaksudsan, Somya Mehra, Zahra Razook, Niall D Geoghegan, Michael J Mlodzianoski, Christopher Dean Goodman, Dawson B Ling, Thorey K Jonsdottir, Joshua Tong, Mufuliat Toyin Famodimu, Mojca Kristan, Harry Pollard, Lindsay B Stewart, Luke Brandner-Garrod, Colin J Sutherland, Michael J Delves, Geoffrey I McFadden, Alyssa E Barry, Brendan S Crabb, Tania F de Koning-Ward, Kelly L Rogers, Alan F Cowman, Wai-Hong Tham, Robin B Gasser, Paul R Gilson
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1. Nature communications 15 (1) (2024)
Robyn McConville, Jelte M M Krol, Ryan W J Steel, Matthew T O'Neill, Bethany K Davey, Anthony N Hodder, Thomas Nebl, Alan F Cowman, Norman Kneteman, Justin A Boddey
Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development. Proceedings of the National Academy of Sciences of the United States of America 121 (28) (2024)
Tony Triglia, Stephen W Scally, Benjamin A Seager, Michał Pasternak, Laura F Dagley, Alan F Cowman
Plasmepsin X activates the PCRCR complex of Plasmodium falciparum by processing PfRh5 for erythrocyte invasion. Nature communications 14 (1) (2023)
Lachlan W Richardson, Trent D Ashton, Madeline G Dans, Nghi Nguyen, Paola Favuzza, Tony Triglia, Anthony N Hodder, Anna Ngo, Kate E Jarman, Alan F Cowman, Robin B Gasser
Substrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity. ChemMedChem 17 (18) (2022)
Stephanie I Studniberg, Lisa J Ioannidis, Retno A S Utami, Leily Trianty, Yang Liao, Waruni Abeysekera, Connie Li Wai Suen, Halina M Pietrzak, Julie Healer, Agatha M Puspitasari, Dwi Apriyanti, Farah N Coutrier, Jeanne Rini Poespoprodjo, Enny Kenangalem, Benediktus Andries, Pak Prayoga, Novita Sariyanti, Aaron T L Lun, Alan F Cowman, Richard N Price, Rintis Noviyanti, Wei Shi, Alexandra L Garnham, Diana S Hansen
Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria. Molecular systems biology 18 (4) (2022)
Michal Pasternak, Julie M J Verhoef, Wilson Wong, Tony Triglia, Michael J Mlodzianoski, Niall D Geoghegan, Cindy Evelyn, Ahmad Z Wardak, Kelly L Rogers, Alan F Cowman
RhopH2 and RhopH3 export enables assembly of the RhopH complex on P. falciparum-infected erythrocyte membranes. Communications biology 5 (1) (2022)
Stephen W Scally, Tony Triglia, Cindy Evelyn, Benjamin A Seager, Michal Pasternak, Pailene S Lim, Julie Healer, Niall D Geoghegan, Amy Adair, Wai-Hong Tham, Laura F Dagley, Kelly L Rogers, Alan F Cowman
PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum. Nature microbiology 7 (12) (2022)
Niall D Geoghegan, Cindy Evelyn, Lachlan W Whitehead, Michal Pasternak, Phoebe McDonald, Tony Triglia, Danushka S Marapana, Daryan Kempe, Jennifer K Thompson, Michael J Mlodzianoski, Julie Healer, Maté Biro, Alan F Cowman, Kelly L Rogers
4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation. Nature communications 12 (1) (2021)
Gregory M LaMonte, Frances Rocamora, Danushka S Marapana, Nina F Gnädig, Sabine Ottilie, Madeline R Luth, Tilla S Worgall, Gregory M Goldgof, Roxanne Mohunlal, T R Santha Kumar, Jennifer K Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M Williams, Bing Yu Zou, Andrea L Cheung, Prianka Kumar, Timothy J Egan, Marcus C S Lee, Dionicio Siegel, Alan F Cowman, David A Fidock, Elizabeth A Winzeler
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. Nature communications 11 (1) (2020)
Julie Healer, Wilson Wong, Jennifer K Thompson, Wengqiang He, Richard W Birkinshaw, Kazutoyo Miura, Carol A Long, Vladislav Soroka, Teit Max Moscote Søgaard, Thomas Jørgensen, Willem A de Jongh, Christopher Weir, Ella Svahn, Peter E Czabotar, Wai-Hong Tham, Ivo Mueller, Paul N Barlow, Alan F Cowman
Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes. Cellular microbiology 21 (7) (2019)
Paul R Gilson, Rasika Kumarasingha, Jennifer Thompson, Xinxin Zhang, Jocelyn Sietsma Penington, Robabeh Kalhor, Hayley E Bullen, Adele M Lehane, Madeline G Dans, Tania F de Koning-Ward, Jessica K Holien, Tatiana P Soares da Costa, Mark D Hulett, Melissa J Buskes, Brendan S Crabb, Kiaran Kirk, Anthony T Papenfuss, Alan F Cowman, Belinda M Abbott
A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4. Scientific reports 9 (1) (2019)
Danushka S Marapana, Laura F Dagley, Jarrod J Sandow, Thomas Nebl, Tony Triglia, Michal Pasternak, Benjamin K Dickerman, Brendan S Crabb, Paul R Gilson, Andrew I Webb, Justin A Boddey, Alan F Cowman
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte. Nature microbiology 3 (9) (2018)
Camila Tenorio França, Michael T White, Wen-Qiang He, Jessica B Hostetler, Jessica Brewster, Gabriel Frato, Indu Malhotra, Jakub Gruszczyk, Christele Huon, Enmoore Lin, Benson Kiniboro, Anjali Yadava, Peter Siba, Mary R Galinski, Julie Healer, Chetan Chitnis, Alan F Cowman, Eizo Takashima, Takafumi Tsuboi, Wai-Hong Tham, Rick M Fairhurst, Julian C Rayner, Christopher L King, Ivo Mueller
Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development. eLife 6 (2017)
Lin Chen, Yibin Xu, Wilson Wong, Jennifer K Thompson, Julie Healer, Ethan D Goddard-Borger, Michael C Lawrence, Alan F Cowman
Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA. eLife 6 (2017)
Xavier Sisquella, Thomas Nebl, Jennifer K Thompson, Lachlan Whitehead, Brian M Malpede, Nichole D Salinas, Kelly Rogers, Niraj H Tolia, Andrea Fleig, Joseph O'Neill, Wai-Hong Tham, F David Horgen, Alan F Cowman
Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion. eLife 6 (2017)
Alexander T Kennedy, Lakshmi C Wijeyewickrema, Alisee Huglo, Clara Lin, Robert N Pike, Alan F Cowman, Wai-Hong Tham
Recruitment of Human C1 Esterase Inhibitor Controls Complement Activation on Blood Stage Plasmodium falciparum Merozoites. Journal of immunology (Baltimore, Md. : 1950) 198 (12) (2017)
Clara S Lin, Alessandro D Uboldi, Christian Epp, Hermann Bujard, Takafumi Tsuboi, Peter E Czabotar, Alan F Cowman
Multiple Plasmodium falciparum Merozoite Surface Protein 1 Complexes Mediate Merozoite Binding to Human Erythrocytes. The Journal of biological chemistry 291 (14) (2016)