Elizabeth A Winzeler (Elizabeth Winzeler)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 63

Top Venues

ACS infectious diseases

Journal of medicinal chemistry

Microbiology spectrum

Nature communications

University of California San Diego

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California San Diego Apr 01 2012

United States

Professor

Publications

Tiantian Jiang, Karla P Godinez-Macias, Jennifer E Collins, Jin Woo Lee, Karen L Wendt, Krypton Carolino, Debopam Chakrabarti, Robert H Cichewicz, Elizabeth A Winzeler
Identification of fungal natural products with potent inhibition in Toxoplasma gondii . Microbiology spectrum 12 (4) (2024)
Jennifer E Collins, Tiantian Jiang, Jin Woo Lee, Karen Wendt, Flore Nardella, Jin Jeon, Raphaella A Paes, Natalia Mojica Santos, Frances Rocamora, Maya Chang, Samuel Schaefer, Robert H Cichewicz, Elizabeth A Winzeler, Debopam Chakrabarti
Understanding the Antiplasmodial Action of Resistance-Refractory Xanthoquinodin A1. ACS infectious diseases 10 (6) (2024)
Tiantian Jiang, Karla P Godinez-Macias, Jennifer E Collins, Jin Woo Lee, Karen L Wendt, Krypton Carolino, Debopam Chakrabarti, Robert H Cichewicz, Elizabeth A Winzeler
Identification of fungal natural products with potent inhibition in Toxoplasma gondii . Microbiology spectrum (2024)
Jennifer E Collins, Tiantian Jiang, Jin Woo Lee, Karen Wendt, Flore Nardella, Jin Jeon, Raphaella A Paes, Natalia Mojica Santos, Frances Rocamora, Maya Chang, Samuel Schaefer, Robert H Cichewicz, Elizabeth A Winzeler, Debopam Chakrabarti
Understanding the Antiplasmodial Action of Resistance-Refractory Xanthoquinodin A1. ACS infectious diseases (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Jair Lage Siqueira-Neto, Kathryn J Wicht, Kelly Chibale, Jeremy N Burrows, David A Fidock, Elizabeth A Winzeler
Author Correction: Antimalarial drug discovery: progress and approaches. Nature reviews. Drug discovery (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Tiantian Jiang, Karla P Godinez-Macias, Jennifer E Collins, Jin Woo Lee, Karen L Wendt, Krypton Carolino, Debopam Chakrabarti, Robert H Cichewicz, Elizabeth A Winzeler
Identification of fungal natural products with potent inhibition in Toxoplasma gondii . Microbiology spectrum 12 (4) (2024)
Tiantian Jiang, Karla P Godinez-Macias, Jennifer E Collins, Jin Woo Lee, Karen L Wendt, Krypton Carolino, Debopam Chakrabarti, Robert H Cichewicz, Elizabeth A Winzeler
Identification of fungal natural products with potent inhibition in Toxoplasma gondii . Microbiology spectrum 12 (4) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Tiantian Jiang, Karla P Godinez-Macias, Jennifer E Collins, Jin Woo Lee, Karen L Wendt, Krypton Carolino, Debopam Chakrabarti, Robert H Cichewicz, Elizabeth A Winzeler
Identification of fungal natural products with potent inhibition in Toxoplasma gondii . Microbiology spectrum 12 (4) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry (2024)
Tiantian Jiang, Karla P Godinez-Macias, Jennifer E Collins, Jin Woo Lee, Karen L Wendt, Krypton Carolino, Debopam Chakrabarti, Robert H Cichewicz, Elizabeth A Winzeler
Identification of fungal natural products with potent inhibition in Toxoplasma gondii . Microbiology spectrum (2024)
William Nguyen, Madeline G Dans, Iain Currie, Jon Kyle Awalt, Brodie L Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Sietsma Penington, Kate E Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G Maier, Giel G van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A Winzeler, Delphine Baud, Stephen Brand, Paul F Jackson, Alan F Cowman, Robin B Gasser
7- N -Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc 1 Complex. ACS infectious diseases 9 (3) (2023)
Jehad Almaliti, Pavla Fajtova, Jaeson Santos Calla-Choque, Gregory M LaMonte, Mudong Feng, Frances Rocamora, Sabine Ottilie, Evgenia Glukhov, Evzen Boura, Raymond T Suhandynata, Jeremiah D Momper, Michael K Gilson, Elizabeth A Winzeler, William H Gerwick, Anthony J O'Donoghue
Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Monica J Bohmer, Jinhua Wang, Eva S Istvan, Madeline R Luth, Jennifer E Collins, Edward L Huttlin, Lushun Wang, Nimisha Mittal, Mingfeng Hao, Nicholas P Kwiatkowski, Steven P Gygi, Ratna Chakrabarti, Xianming Deng, Daniel E Goldberg, Elizabeth A Winzeler, Nathanael S Gray, Debopam Chakrabarti
Human Polo-like Kinase Inhibitors as Antiplasmodials. ACS infectious diseases (2023)
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, Pamela Magistrado-Coxen, Kyra A Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S Nasamu, Allison R Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M Early, Amanda K Lukens, Danny Milner, Jeremy D Furtado, Francisco-Javier Gamo, Elizabeth A Winzeler, Sarah K Volkman, Maëlle Duffey, Benoît Laleu, David A Fidock, Susan Wyllie, Jacquin C Niles, Dyann F Wirth
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation. Nature communications 14 (1) (2023)
Leah S Imlay, Aloysus K Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal, Sergio Wittlin, Alisje Churchyard, Hanspeter Niederstrasser, Benigno F Crespo-Fernandez, Bruce A Posner, Francisco Javier Gamo, Jake Baum, Elizabeth A Winzeler, Benoît Laleu, Joseph M Ready, Margaret A Phillips
Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL). ACS infectious diseases 9 (3) (2023)
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, Pamela Magistrado-Coxen, Kyra A Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S Nasamu, Allison R Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M Early, Amanda K Lukens, Danny Milner, Jeremy D Furtado, Francisco-Javier Gamo, Elizabeth A Winzeler, Sarah K Volkman, Maëlle Duffey, Benoît Laleu, David A Fidock, Susan Wyllie, Jacquin C Niles, Dyann F Wirth
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation. Nature communications 14 (1) (2023)
William Nguyen, Madeline G Dans, Iain Currie, Jon Kyle Awalt, Brodie L Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Sietsma Penington, Kate E Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G Maier, Giel G van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A Winzeler, Delphine Baud, Stephen Brand, Paul F Jackson, Alan F Cowman, Robin B Gasser
7- N -Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc 1 Complex. ACS infectious diseases (2023)
Eva S Istvan, Francisco M Guerra, Matthew Abraham, Kuo-Sen Huang, Frances Rocamora, Haoshuang Zhao, Lan Xu, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Madeline R Luth, Haissi Cui, Tuo Yang, Sara Palomo Diaz, Maria G Gomez-Lorenzo, Tarrick Qahash, Nimisha Mittal, Sabine Ottilie, Jacquin C Niles, Marcus Chee San Lee, Manuel Llinás, Nobutaka Kato, John Okombo, David A Fidock, Paul Schimmel, Francisco Javier Gamo, Daniel E Goldberg, Elizabeth A Winzeler
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science translational medicine 15 (686) (2023)
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, Pamela Magistrado-Coxen, Kyra A Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S Nasamu, Allison R Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M Early, Amanda K Lukens, Danny Milner, Jeremy D Furtado, Francisco-Javier Gamo, Elizabeth A Winzeler, Sarah K Volkman, Maëlle Duffey, Benoît Laleu, David A Fidock, Susan Wyllie, Jacquin C Niles, Dyann F Wirth
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation. Nature communications 14 (1) (2023)
William Nguyen, Madeline G Dans, Iain Currie, Jon Kyle Awalt, Brodie L Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Sietsma Penington, Kate E Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G Maier, Giel G van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A Winzeler, Delphine Baud, Stephen Brand, Paul F Jackson, Alan F Cowman, Robin B Gasser
7- N -Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc 1 Complex. ACS infectious diseases 9 (3) (2023)
Eva S Istvan, Francisco M Guerra, Matthew Abraham, Kuo-Sen Huang, Frances Rocamora, Haoshuang Zhao, Lan Xu, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Madeline R Luth, Haissi Cui, Tuo Yang, Sara Palomo Diaz, Maria G Gomez-Lorenzo, Tarrick Qahash, Nimisha Mittal, Sabine Ottilie, Jacquin C Niles, Marcus Chee San Lee, Manuel Llinás, Nobutaka Kato, John Okombo, David A Fidock, Paul Schimmel, Francisco Javier Gamo, Daniel E Goldberg, Elizabeth A Winzeler
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science translational medicine 15 (686) (2023)
Leah S Imlay, Aloysus K Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal, Sergio Wittlin, Alisje Churchyard, Hanspeter Niederstrasser, Benigno F Crespo-Fernandez, Bruce A Posner, Francisco Javier Gamo, Jake Baum, Elizabeth A Winzeler, Benoît Laleu, Joseph M Ready, Margaret A Phillips
Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL). ACS infectious diseases (2023)
Rebecca E K Mandt, Madeline R Luth, Mark A Tye, Ralph Mazitschek, Sabine Ottilie, Elizabeth A Winzeler, Maria Jose Lafuente-Monasterio, Francisco Javier Gamo, Dyann F Wirth, Amanda K Lukens
Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance. eLife 12 (2023)
Leah S Imlay, Aloysus K Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal, Sergio Wittlin, Alisje Churchyard, Hanspeter Niederstrasser, Benigno F Crespo-Fernandez, Bruce A Posner, Francisco Javier Gamo, Jake Baum, Elizabeth A Winzeler, Benoît Laleu, Joseph M Ready, Margaret A Phillips
Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL). ACS infectious diseases 9 (3) (2023)
Jair Lage Siqueira-Neto, Kathryn J Wicht, Kelly Chibale, Jeremy N Burrows, David A Fidock, Elizabeth A Winzeler
Antimalarial drug discovery: progress and approaches. Nature reviews. Drug discovery (2023)
William Nguyen, Madeline G Dans, Iain Currie, Jon Kyle Awalt, Brodie L Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Sietsma Penington, Kate E Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G Maier, Giel G van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A Winzeler, Delphine Baud, Stephen Brand, Paul F Jackson, Alan F Cowman, Robin B Gasser
7- N -Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc 1 Complex. ACS infectious diseases 9 (3) (2023)
William Nguyen, Madeline G Dans, Iain Currie, Jon Kyle Awalt, Brodie L Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Sietsma Penington, Kate E Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G Maier, Giel G van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A Winzeler, Delphine Baud, Stephen Brand, Paul F Jackson, Alan F Cowman, Robin B Gasser
7- N -Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc 1 Complex. ACS infectious diseases 9 (3) (2023)
Leah S Imlay, Aloysus K Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal, Sergio Wittlin, Alisje Churchyard, Hanspeter Niederstrasser, Benigno F Crespo-Fernandez, Bruce A Posner, Francisco Javier Gamo, Jake Baum, Elizabeth A Winzeler, Benoît Laleu, Joseph M Ready, Margaret A Phillips
Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL). ACS infectious diseases 9 (3) (2023)
Eva S Istvan, Francisco M Guerra, Matthew Abraham, Kuo-Sen Huang, Frances Rocamora, Haoshuang Zhao, Lan Xu, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Madeline R Luth, Haissi Cui, Tuo Yang, Sara Palomo Diaz, Maria G Gomez-Lorenzo, Tarrick Qahash, Nimisha Mittal, Sabine Ottilie, Jacquin C Niles, Marcus Chee San Lee, Manuel Llinás, Nobutaka Kato, John Okombo, David A Fidock, Paul Schimmel, Francisco Javier Gamo, Daniel E Goldberg, Elizabeth A Winzeler
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science translational medicine 15 (686) (2023)
Monica J Bohmer, Jinhua Wang, Eva S Istvan, Madeline R Luth, Jennifer E Collins, Edward L Huttlin, Lushun Wang, Nimisha Mittal, Mingfeng Hao, Nicholas P Kwiatkowski, Steven P Gygi, Ratna Chakrabarti, Xianming Deng, Daniel E Goldberg, Elizabeth A Winzeler, Nathanael S Gray, Debopam Chakrabarti
Human Polo-like Kinase Inhibitors as Antiplasmodials. ACS infectious diseases (2023)
Stanley C Xie, Riley D Metcalfe, Elyse A Dunn, Craig J Morton, Shih-Chung Huang, Tanya Puhalovich, Yawei Du, Sergio Wittlin, Shuai Nie, Madeline R Luth, Liting Ma, Mi-Sook Kim, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Carlo Giannangelo, Fiona J Houghton, Alisje Churchyard, Mufuliat T Famodimu, Daniel C Barry, David L Gillett, Sumanta Dey, Clara C Kosasih, William Newman, Jacquin C Niles, Marcus Chee San Lee, Jake Baum, Sabine Ottilie, Elizabeth A Winzeler, Darren John Creek, Nicholas A Williamson, Michael W Parker, Stephen Brand, Steven P Langston, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy. Science (New York, N.Y.) 376 (6597) (2022)
Sabine Ottilie, Madeline R Luth, Erich Hellemann, Gregory M Goldgof, Eddy Vigil, Prianka Kumar, Andrea L Cheung, Miranda J Song, Karla P Godinez-Macias, Krypton Carolino, Jennifer Yang, Gisel Lopez, Matthew Abraham, Maureen Tarsio, Emmanuelle V LeBlanc, Luke Whitesell, Jake Schenken, Felicia Gunawan, Reysha Patel, Joshua Smith, Melissa S Love, Roy M Williams, Case W McNamara, William H Gerwick, Trey Ideker, Yo Suzuki, Dyann F Wirth, Amanda K Lukens, Patricia M Kane, Leah E Cowen, Jacob D Durrant, Elizabeth A Winzeler
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance. Communications biology 5 (1) (2022)
Michael J Palmer, Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey Gerasyuto, Sreekanth Kokkonda, Farah El Mazouni, John White, Karen L White, Josefine Striepen, Jade Bath, Kyra A Schindler, Tomas Yeo, David M Shackleford, Sachel Mok, Ioanna Deni, Aloysus Lawong, Ann Huang, Gong Chen, Wen Wang, Jaya Jayaseelan, Kasiram Katneni, Rahul Patil, Jessica Saunders, Shatrughan P Shahi, Rajesh Chittimalla, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Sergio Wittlin, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Anna Caroline Campos Aguiar, Rafael V C Guido, Dhelio B Pereira, Nimisha Mittal, Elizabeth A Winzeler, Diana R Tomchick, Benoît Laleu, Jeremy N Burrows, Pradipsinh K Rathod, David A Fidock, Susan A Charman, Margaret A Phillips
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series. Journal of medicinal chemistry 64 (9) (2021)
Frances Rocamora, Purva Gupta, Eva S Istvan, Madeline R Luth, Emma F Carpenter, Krittikorn Kümpornsin, Erika Sasaki, Jaeson Calla, Nimisha Mittal, Krypton Carolino, Edward Owen, Manuel Llinás, Sabine Ottilie, Daniel E Goldberg, Marcus C S Lee, Elizabeth A Winzeler
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum. ACS infectious diseases 7 (4) (2021)
Aloysus Lawong, Suraksha Gahalawat, John Okombo, Josefine Striepen, Tomas Yeo, Sachel Mok, Ioanna Deni, Jessica L Bridgford, Hanspeter Niederstrasser, Anwu Zhou, Bruce Posner, Sergio Wittlin, Francisco Javier Gamo, Benigno Crespo, Alisje Churchyard, Jake Baum, Nimisha Mittal, Elizabeth A Winzeler, Benoît Laleu, Michael J Palmer, Susan A Charman, David A Fidock, Joseph M Ready, Margaret A Phillips
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum. Journal of medicinal chemistry 64 (5) (2021)
Stanley C Xie, Riley D Metcalfe, Hirotake Mizutani, Tanya Puhalovich, Eric Hanssen, Craig J Morton, Yawei Du, Con Dogovski, Shih-Chung Huang, Jeffrey Ciavarri, Paul Hales, Robert J Griffin, Lawrence H Cohen, Bei-Ching Chuang, Sergio Wittlin, Ioanna Deni, Tomas Yeo, Kurt E Ward, Daniel C Barry, Boyin Liu, David L Gillett, Benigno F Crespo-Fernandez, Sabine Ottilie, Nimisha Mittal, Alisje Churchyard, Daniel Ferguson, Anna Caroline Campos Aguiar, Rafael Victorio Carvalho Guido, Jake Baum, Kirsten K Hanson, Elizabeth A Winzeler, Francisco Javier Gamo, David A Fidock, Delphine Baud, Michael W Parker, Stephen Brand, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America 118 (39) (2021)
Janette Reader, Mariëtte E van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Sabine Ottilie, Anjo Theron, Phanankosi Moyo, Erica Erlank, Luisa Nardini, Nelius Venter, Sonja Lauterbach, Belinda Bezuidenhout, André Horatscheck, Ashleigh van Heerden, Natalie J Spillman, Anne N Cowell, Jessica Connacher, Daniel Opperman, Lindsey M Orchard, Manuel Llinás, Eva S Istvan, Daniel E Goldberg, Grant A Boyle, David Calvo, Dalu Mancama, Theresa L Coetzer, Elizabeth A Winzeler, James Duffy, Lizette Leonie Koekemoer, Gregory S Basarab, Kelly Chibale, Lyn-Marié Birkholtz
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box. Nature communications 12 (1) (2021)
Barbara Forte, Sabine Ottilie, Andrew Plater, Brice Campo, Koen J Dechering, Francisco Javier Gamo, Daniel E Goldberg, Eva S Istvan, Marcus Lee, Amanda K Lukens, Case W MacNamara, Jacquin C Niles, John Okombo, Charisse Flerida A Pasaje, Miles G Siegel, Dyann Wirth, Susan Wyllie, David A Fidock, Beatriz Baragaña, Elizabeth A Winzeler, Ian H Gilbert
Prioritization of Molecular Targets for Antimalarial Drug Discovery. ACS infectious diseases 7 (10) (2021)
Scott Eagon, Jared T Hammill, Martina Sigal, Kevin J Ahn, Julia E Tryhorn, Grant Koch, Briana Belanger, Cory A Chaplan, Lauren Loop, Anna S Kashtanova, Kenya Yniguez, Horacio Lazaro, Steven P Wilkinson, Amy L Rice, Mofolusho O Falade, Rei Takahashi, Katie Kim, Ashley Cheung, Celine DiBernardo, Joshua J Kimball, Elizabeth A Winzeler, Korina Eribez, Nimisha Mittal, Francisco-Javier Gamo, Benigno Crespo, Alisje Churchyard, Irene García-Barbazán, Jake Baum, Marc O Anderson, Benoît Laleu, R Kiplin Guy
Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines. Journal of medicinal chemistry 63 (20) (2020)
Erica Silva, Manuel Michaca, Brenton Munson, Gordon J Bean, Philipp A Jaeger, Katherine Licon, Elizabeth A Winzeler, Trey Ideker
Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response. G3 (Bethesda, Md.) 10 (9) (2020)
Gregory M LaMonte, Frances Rocamora, Danushka S Marapana, Nina F Gnädig, Sabine Ottilie, Madeline R Luth, Tilla S Worgall, Gregory M Goldgof, Roxanne Mohunlal, T R Santha Kumar, Jennifer K Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M Williams, Bing Yu Zou, Andrea L Cheung, Prianka Kumar, Timothy J Egan, Marcus C S Lee, Dionicio Siegel, Alan F Cowman, David A Fidock, Elizabeth A Winzeler
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. Nature communications 11 (1) (2020)
Mahmood M Alam, Ana Sanchez-Azqueta, Omar Janha, Erika L Flannery, Amit Mahindra, Kopano Mapesa, Aditya B Char, Dev Sriranganadane, Nicolas M B Brancucci, Yevgeniya Antonova-Koch, Kathryn Crouch, Nelson Victor Simwela, Scott B Millar, Jude Akinwale, Deborah Mitcheson, Lev Solyakov, Kate Dudek, Carolyn Jones, Cleofé Zapatero, Christian Doerig, Davis C Nwakanma, Maria Jesús Vázquez, Gonzalo Colmenarejo, Maria Jose Lafuente-Monasterio, Maria Luisa Leon, Paulo H C Godoi, Jonathan M Elkins, Andrew P Waters, Andrew G Jamieson, Elena Fernández Álvaro, Lisa C Ranford-Cartwright, Matthias Marti, Elizabeth A Winzeler, Francisco Javier Gamo, Andrew B Tobin
Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science (New York, N.Y.) 365 (6456) (2020)
Matthew Abraham, Kerstin Gagaring, Marisa L Martino, Manu Vanaerschot, David M Plouffe, Jaeson Calla, Karla P Godinez-Macias, Alan Y Du, Melanie Wree, Yevgeniya Antonova-Koch, Korina Eribez, Madeline R Luth, Sabine Ottilie, David A Fidock, Case W MacNamara, Elizabeth A Winzeler
Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials. ACS infectious diseases 6 (4) (2020)
Rebecca E K Mandt, Maria Jose Lafuente-Monasterio, Tomoyo Sakata-Kato, Madeline R Luth, Delfina Segura-Carro, Alba Pablos-Tanarro, Sara Viera, Noemi Magan, Sabine Ottilie, Elizabeth A Winzeler, Amanda K Lukens, Francisco Javier Gamo, Dyann F Wirth
In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model. Science translational medicine 11 (521) (2020)
Eva S Istvan, Sudipta Das, Suyash Bhatnagar, Josh R Beck, Edward Owen, Manuel Llinás, Suresh M Ganesan, Jacquin C Niles, Elizabeth A Winzeler, Akhil B Vaidya, Daniel E Goldberg
Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis. eLife 8 (2019)
Alex Rosenberg, Madeline R Luth, Elizabeth A Winzeler, Michael Behnke, L David Sibley
Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America (2019)
Elizabeth A Winzeler, Sabine Ottilie
The proteasome as a target: How not tidying up can have toxic consequences for parasitic protozoa. Proceedings of the National Academy of Sciences of the United States of America 116 (21) (2019)
Barbara H Stokes, Euna Yoo, James M Murithi, Madeline R Luth, Pavel Afanasyev, Paula C A da Fonseca, Elizabeth A Winzeler, Caroline L Ng, Matthew M Bogyo, David A Fidock
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents. PLoS pathogens 15 (6) (2019)
Yevgeniya Antonova-Koch, Stephan Meister, Matthew Abraham, Madeline R Luth, Sabine Ottilie, Amanda K Lukens, Tomoyo Sakata-Kato, Manu Vanaerschot, Edward Owen, Juan Carlos Jado, Steven P Maher, Jaeson Santos Calla-Choque, David Plouffe, Yang Zhong, Kaisheng Chen, Victor Chaumeau, Amy J Conway, Case W McNamara, Maureen Ibanez, Kerstin Gagaring, Fernando Neria Serrano, Korina Eribez, Cullin McLean Taggard, Andrea L Cheung, Christie Lincoln, Biniam Ambachew, Melanie Rouillier, Dionicio Siegel, Francois H Nosten, Dennis E Kyle, Francisco-Javier Gamo, Yingyao Zhou, Manuel Llinás, David A Fidock, Dyann F Wirth, Jeremy N Burrows, Brice Campo, Elizabeth A Winzeler
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science (New York, N.Y.) 362 (6419) (2019)
Elizabeth A Winzeler
An improbable journey: Creativity helped me make the transition from art to curing malaria. The Journal of biological chemistry 294 (2) (2018)
Annie N Cowell, Eva S Istvan, Amanda K Lukens, Maria G Gomez-Lorenzo, Manu Vanaerschot, Tomoyo Sakata-Kato, Erika L Flannery, Pamela Magistrado, Edward Owen, Matthew Abraham, Gregory LaMonte, Heather J Painter, Roy M Williams, Virginia Franco, María Linares, Ignacio Arriaga, Selina Bopp, Victoria C Corey, Nina F Gnädig, Olivia Coburn-Flynn, Christin Reimer, Purva Gupta, James M Murithi, Pedro A Moura, Olivia Fuchs, Erika Sasaki, Sang W Kim, Christine H Teng, Lawrence T Wang, Aslı Akidil, Sophie Adjalley, Paul A Willis, Dionicio Siegel, Olga Tanaseichuk, Yang Zhong, Yingyao Zhou, Manuel Llinás, Sabine Ottilie, Francisco-Javier Gamo, Marcus Chee San Lee, Daniel E Goldberg, David A Fidock, Dyann F Wirth, Elizabeth A Winzeler
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science (New York, N.Y.) 359 (6372) (2018)
Marta Moreno, Carlos Tong-Rios, Pamela Orjuela-Sanchez, Gabriel Carrasco-Escobar, Brice Campo, Dionicia Gamboa, Elizabeth A Winzeler, Joseph Michael Vinetz
Continuous Supply of Plasmodium vivax Sporozoites from Colonized Anopheles darlingi in the Peruvian Amazon. ACS infectious diseases 4 (4) (2018)
Madeline R Luth, Purva Gupta, Sabine Ottilie, Elizabeth A Winzeler
Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery. ACS infectious diseases 4 (3) (2018)
Pamela Orjuela-Sanchez, Zaira Hellen Villa, Marta Moreno, Carlos Tong-Rios, Stephan Meister, Gregory M LaMonte, Brice Campo, Joseph Michael Vinetz, Elizabeth A Winzeler
Developing Plasmodium vivax Resources for Liver Stage Study in the Peruvian Amazon Region. ACS infectious diseases 4 (4) (2018)
Stanley C Xie, David L Gillett, Natalie J Spillman, Christopher Tsu, Madeline R Luth, Sabine Ottilie, Sandra Duffy, Alexandra E Gould, Paul Hales, Benjamin A Seager, Carlie L Charron, Frank Bruzzese, Xiaofeng Yang, Xiansi Zhao, Shih-Chung Huang, Craig A Hutton, Jeremy N Burrows, Elizabeth A Winzeler, Vicky M Avery, Lawrence R Dick, Leann Tilley
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome. Journal of medicinal chemistry 61 (22) (2018)
Regina N Rabinovich, Chris Drakeley, Abdoulaye A Djimde, B Fenton Hall, Simon I Hay, Janet Hemingway, David C Kaslow, Abdisalan Noor, Fredros Okumu, Richard Steketee, Marcel Tanner, Timothy N C Wells, Maxine A Whittaker, Elizabeth A Winzeler, Dyann F Wirth, Kate Whitfield, Pedro L Alonso
malERA: An updated research agenda for malaria elimination and eradication. PLoS medicine 14 (11) (2017)
Michael Leven, Tanja C Knaab, Jana Held, Sandra Duffy, Stephan Meister, Christoph Fischli, Diane Meitzner, Ursula Lehmann, Beate Lungerich, Krystina Kuna, Petra Stahlke, Michael J Delves, Mirko Buchholz, Elizabeth A Winzeler, Vicky M Avery, Benjamin Mordmüller, Sergio Wittlin, Thomas Kurz
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of medicinal chemistry 60 (14) (2017)
Gregory M LaMonte, Jehad Almaliti, Betsaida Bibo-Verdugo, Lena Keller, Bing Yu Zou, Jennifer Yang, Yevgeniya Antonova-Koch, Pamela Orjuela-Sanchez, Colleen A Boyle, Edgar Vigil, Lawrence Wang, Gregory M Goldgof, Lena Gerwick, Anthony J O'Donoghue, Elizabeth A Winzeler, William H Gerwick, Sabine Ottilie
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. Journal of medicinal chemistry 60 (15) (2017)
Sabine Ottilie, Gregory M Goldgof, Claudia Magalhaes Calvet, Gareth K Jennings, Greg LaMonte, Jake Schenken, Edgar Vigil, Prianka Kumar, Laura-Isobel McCall, Eduardo Soares Constantino Lopes, Felicia Gunawan, Jennifer Yang, Yo Suzuki, Jair L Siqueira-Neto, James H McKerrow, Rommie E Amaro, Larissa M Podust, Jacob D Durrant, Elizabeth A Winzeler
Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast. ACS chemical biology 12 (2) (2016)

Elizabeth A Winzeler.css-eqlu8i{font-size:small;padding-left:4px;} (Elizabeth Winzeler)

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Elizabeth A Winzeler (Elizabeth Winzeler)