Alex Sigal (A Sigal)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 43

Top Venues

eLife

Nature communications

PLOS global public health

Nature

This page only lists publications with an associated author ORCID identifier.

Publications

Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi S B Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Maxine Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, F Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo, Simone I Richardson, Sharana Mahomed, Helen V Rees, Linda Gail Bekker, Glenda Elisabeth Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. PLOS global public health 4 (4) (2024)
S Jaumdally, M Tomasicchio, A Pooran, A Esmail, A Kotze, S Meier, L Wilson, S Oelofse, C van der Merwe, A Roomaney, M Davids, T Suliman, R Joseph, T Perumal, Alex J Scott, Megan L Shaw, Wolfgang Preiser, Carolyn Williamson, A Goga, Elizabeth Sarah Mayne, G Gray, Penny L Moore, Alex Sigal, Jason D Limberis, J Metcalfe, Keertan Dheda
Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature communications 15 (1) (2024)
S Jaumdally, M Tomasicchio, A Pooran, A Esmail, A Kotze, S Meier, L Wilson, S Oelofse, C van der Merwe, A Roomaney, M Davids, T Suliman, R Joseph, T Perumal, Alex J Scott, Megan L Shaw, Wolfgang Preiser, Carolyn Williamson, A Goga, Elizabeth Sarah Mayne, G Gray, Penny L Moore, Alex Sigal, Jason D Limberis, J Metcalfe, Keertan Dheda
Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature communications 15 (1) (2024)
Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi S B Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Maxine Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, F Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo, Simone I Richardson, Sharana Mahomed, Helen V Rees, Linda Gail Bekker, Glenda Elisabeth Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. PLOS global public health 4 (4) (2024)
S Jaumdally, M Tomasicchio, A Pooran, A Esmail, A Kotze, S Meier, L Wilson, S Oelofse, C van der Merwe, A Roomaney, M Davids, T Suliman, R Joseph, T Perumal, Alex J Scott, Megan L Shaw, Wolfgang Preiser, Carolyn Williamson, A Goga, Elizabeth Sarah Mayne, G Gray, Penny L Moore, Alex Sigal, Jason D Limberis, J Metcalfe, Keertan Dheda
Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature communications 15 (1) (2024)
Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi S B Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Maxine Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, F Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo, Simone I Richardson, Sharana Mahomed, Helen V Rees, Linda Gail Bekker, Glenda Elisabeth Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. PLOS global public health 4 (4) (2024)
Barbara Mühlemann, Samuel H Wilks, Lauren Baracco, Meriem Bekliz, Juan Manuel Carreño, Victor Max Corman, Meredith E Davis-Gardner, Wanwisa Dejnirattisai, Michael S. Diamond, Daniel C Douek, Christian Drosten, Isabella Eckerle, Venkata-Viswanadh Edara, Madison Leigh Ellis, Ron A M Fouchier, Matthew B Friemann, Sucheta Godbole, Bart L Haagmans, Peter J Halfmann, Amy R Henry, Terry C Jones, Leah C Katzelnick, Yoshihiro Kawaoka, Janine Kimpel, Florian Krammer, Lilin Lai, Chang Liu, Sabrina Lusvarghi, Benjamin Meyer, Juthathip Mongkolsapaya, David C Montefiori, Anna Z Mykytyn, Antonia Netzl, Simon Pollett, Annika Rössler, Gavin R Screaton, Xiaoying X Shen, Alex Sigal, Viviana Simon, Rahul Subramanian, Piyada Supasa, Mehul S Suthar, Sina Türeli, Wei Wang, Carol D Weiss, Derek J Smith
Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays. Science translational medicine 16 (747) (2024)
S Jaumdally, M Tomasicchio, A Pooran, A Esmail, A Kotze, S Meier, L Wilson, S Oelofse, C van der Merwe, A Roomaney, M Davids, T Suliman, R Joseph, T Perumal, Alex J Scott, Megan L Shaw, Wolfgang Preiser, Carolyn Williamson, A Goga, Elizabeth Sarah Mayne, G Gray, Penny L Moore, Alex Sigal, Jason D Limberis, J Metcalfe, Keertan Dheda
Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature communications 15 (1) (2024)
Barbara Mühlemann, Samuel H Wilks, Lauren Baracco, Meriem Bekliz, Juan Manuel Carreño, Victor Max Corman, Meredith E Davis-Gardner, Wanwisa Dejnirattisai, Michael S. Diamond, Daniel C Douek, Christian Drosten, Isabella Eckerle, Venkata-Viswanadh Edara, Madison Leigh Ellis, Ron A M Fouchier, Matthew B Friemann, Sucheta Godbole, Bart L Haagmans, Peter J Halfmann, Amy R Henry, Terry C Jones, Leah C Katzelnick, Yoshihiro Kawaoka, Janine Kimpel, Florian Krammer, Lilin Lai, Chang Liu, Sabrina Lusvarghi, Benjamin Meyer, Juthathip Mongkolsapaya, David C Montefiori, Anna Z Mykytyn, Antonia Netzl, Simon Pollett, Annika Rössler, Gavin R Screaton, Xiaoying X Shen, Alex Sigal, Viviana Simon, Rahul Subramanian, Piyada Supasa, Mehul S Suthar, Sina Türeli, Wei Wang, Carol D Weiss, Derek J Smith
Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays. Science translational medicine 16 (747) (2024)
Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi S B Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Maxine Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, F Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo, Simone I Richardson, Sharana Mahomed, Helen V Rees, Linda Gail Bekker, Glenda Elisabeth Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. PLOS global public health 4 (4) (2024)
Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi S B Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Maxine Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela Fj Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, F Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo, Simone I Richardson, Sharana Mahomed, Helen V Rees, Linda Gail Bekker, Glenda Elisabeth Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. medRxiv : the preprint server for health sciences (2023)
Gila Lustig, Yashica Ganga, Hylton E Rodel, Houriiyah Tegally, Afrah Khairallah, Laurelle Jackson, Sandile Cele, Khadija Khan, Zesuliwe Jule, Kajal Reedoy, Farina Karim, Mallory Bernstein, Thumbi Ndung'u, Mahomed-Yunus S Moosa, Derseree Archary, Tulio de Oliveira, Richard Lessells, Richard A Neher, Salim S Abdool Karim, Alex Sigal
SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations. Virus evolution 10 (1) (2023)
Khadija Khan, Gila Lustig, Cornelius Römer, Kajal Reedoy, Zesuliwe Jule, Farina Karim, Yashica Ganga, Mallory Bernstein, Zainab Baig, Laurelle Jackson, Boitshoko Mahlangu, Anele Mnguni, Ayanda Nzimande, Nadine Stock, Dikeledi Kekana, Buhle Ntozini, Cindy van Deventer, Terry Marshall, Nithendra Manickchund, Bernadett I Gosnell, Richard J Lessells, Quarraisha Abdool Karim, Salim S Abdool Karim, Mahomed-Yunus S Moosa, Tulio de Oliveira, Anne von Gottberg, Nicole Wolter, Richard A Neher, Alex Sigal
Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant. Nature communications 14 (1) (2023)
Alex Sigal
Boosting in the age of Omicron. eLife 12 (2023)
Robert G E Krause, Thandeka Moyo, Simone I Richardson, Zanele Makhado, Nelia P Manamela, Tandile Hermanus, Nonhlanhla N Mkhize, Roanne Keeton, Ntombi Benede, Mathilda Mennen, Sango Skelem, Farina Karim, Khadija Khan, Catherine Riou, Ntobeko A B Ntusi, Ameena Goga, Glenda Gray, Willem A Hanekom, Sharana Mahomed, Linda Gail Bekker, Andreas Groll, Alex Sigal, Penny L Moore, Wendy A Burgers, Alasdair Leslie
Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells. NPJ vaccines 8 (1) (2023)
Gila Lustig, Yashica Ganga, Hylton E Rodel, Houriiyah Tegally, Afrah Khairallah, Laurelle Jackson, Sandile Cele, Khadija Khan, Zesuliwe Jule, Kajal Reedoy, Farina Karim, Mallory Bernstein, Thumbi Ndung'u, Mahomed-Yunus S Moosa, Derseree Archary, Tulio de Oliveira, Richard Lessells, Richard A Neher, Salim S Abdool Karim, Alex Sigal
SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations. Virus evolution 10 (1) (2023)
Cathrine Scheepers, Josie Everatt, Daniel Gyamfi Amoako, Houriiyah Tegally, Constantinos Kurt Wibmer, Anele Mnguni, Arshad Ismail, Boitshoko Mahlangu, Bronwen E Lambson, Darren P Martin, Eduan Wilkinson, James Emmanuel San, Jennifer Giandhari, Nelia Manamela, Noxolo Ntuli, Prudence Kgagudi, Sandile Cele, Simone I Richardson, Sureshnee Pillay, Thabo Mohale, Upasana Ramphal, Yeshnee Naidoo, Zamantungwa T Khumalo, Gaurav Kwatra, Glenda Gray, Linda-Gail Bekker, Shabir A Madhi, Vicky Baillie, Wesley C Van Voorhis, Florette K Treurnicht, Marietjie Venter, Koleka Mlisana, Nicole Wolter, Alex Sigal, Carolyn Williamson, Nei-Yuan Hsiao, Nokukhanya Msomi, Tongai Gibson Maponga, Wolfgang Preiser, Zinhle Makatini, Richard J Lessells, Penny L Moore, Tulio de Oliveira, Anne von Gottberg, Jinal N Bhiman
Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage. Nature communications 13 (1) (2022)
Khadija Khan, Farina Karim, Sandile Cele, James Emmanuel San, Gila Lustig, Houriiyah Tegally, Yuval Rosenberg, Mallory Bernstein, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Nokuthula Ngcobo, Yoliswa Miya, Matilda Mazibuko, Ntombifuthi Mthabela, Zoey Mhlane, Nikiwe Mbatha, Jennifer Giandhari, Yajna Ramphal, Taryn Naidoo, Nithendra Manickchund, Nombulelo Magula, Salim Abdool Karim, Glenda Gray, Willem Hanekom, Anne von Gottberg, Ron Milo, Bernadett Gosnell, Richard Lessells, Tulio de Oliveira, Penny Moore, Yunus S Moosa, Alex Sigal
Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant. medRxiv : the preprint server for health sciences (2022)
Khadija Khan, Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy, Sandile Cele, Gila Lustig, Daniel Gyamfi Amoako, Nicole Wolter, Natasha Samsunder, Aida Sivro, James Emmanuel San, Jennifer Giandhari, Houriiyah Tegally, Sureshnee Pillay, Yeshnee Naidoo, Matilda Mazibuko, Yoliswa Miya, Nokuthula Ngcobo, Nithendra Manickchund, Nombulelo Magula, Quarraisha Abdool Karim, Anne von Gottberg, Salim S Abdool Karim, Willem Hanekom, Bernadett I Gosnell, null null, Richard J Lessells, Tulio de Oliveira, Mahomed-Yunus S Moosa, Alex Sigal
Author Correction: Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nature communications 13 (1) (2022)
Darren P Martin, Spyros Lytras, Alexander G Lucaci, Wolfgang Maier, Björn Grüning, Stephen D Shank, Steven Weaver, Oscar A MacLean, Richard J Orton, Philippe Lemey, Maciej F Boni, Houriiyah Tegally, Gordon W Harkins, Cathrine Scheepers, Jinal N Bhiman, Josie Everatt, Daniel G Amoako, James Emmanuel San, Jennifer Giandhari, Alex Sigal, null null, Carolyn Williamson, Nei-Yuan Hsiao, Anne von Gottberg, Arne De Klerk, Robert W Shafer, David L Robertson, Robert J Wilkinson, B Trevor Sewell, Richard Lessells, Anton Nekrutenko, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Ben Murrell, Eduan Wilkinson, Ravindra Kumar Gupta, Tulio de Oliveira, Sergei L Kosakovsky Pond
Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function. Molecular biology and evolution 39 (4) (2022)
Roanne Keeton, Marius Belmondo Tincho, Amkele Ngomti, Richard Baguma, Ntombi S B Benede, Akiko Suzuki, Khadija Khan, Sandile Cele, Mallory Bernstein, Farina Karim, Sharon V Madzorera, Thandeka Moyo-Gwete, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Daniel Mutithu, Olukayode Aremu, Cari Stek, Elsa du Bruyn, Mieke A Van Der Mescht, Zelda de Beer, Talita R de Villiers, Annie Bodenstein, Gretha van den Berg, Adriano Mendes, Amy Strydom, Marietjie Venter, Jennifer Giandhari, Yeshnee Naidoo, Sureshnee Pillay, Houriiyah Tegally, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Robert J Wilkinson, Tulio de Oliveira, Linda-Gail Bekker, Glenda Gray, Veronica Ueckermann, Theresa Rossouw, Michael T Boswell, Jinal N Bhiman, Penny L Moore, Alex Sigal, Ntobeko A B Ntusi, Wendy A Burgers, Catherine Riou
T cell responses to SARS-CoV-2 spike cross-recognize Omicron. Nature 603 (7901) (2022)
Alex Sigal, Ron Milo, Waasila Jassat
Estimating disease severity of Omicron and Delta SARS-CoV-2 infections. Nature reviews. Immunology 22 (5) (2022)
Chee Wah Tan, Wan Ni Chia, Feng Zhu, Barnaby Edward Young, Napaporn Chantasrisawad, Shi-Hsia Hwa, Aileen Ying-Yan Yeoh, Beng Lee Lim, Wee Chee Yap, Surinder Kaur M S Pada, Seow Yen Tan, Watsamon Jantarabenjakul, Lim Kai Toh, Shiwei Chen, Jinyan Zhang, Yun Yan Mah, Vivian Chih-Wei Chen, Mark I-C Chen, Supaporn Wacharapluesadee, Alex Sigal, Opass Putcharoen, David Chien Lye, Lin-Fa Wang
SARS-CoV-2 Omicron variant emerged under immune selection. Nature microbiology 7 (11) (2022)
Thandeka Nkosi, Caroline Chasara, Andrea Olga Papadopoulos, Tiza L Nguni, Farina Karim, Mahomed-Yunus S Moosa, Inbal Gazy, Kondwani Jambo, null null, Willem Hanekom, Alex Sigal, Zaza Mtine Ndhlovu
Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition. eLife 11 (2022)
Robert Krause, Jumari Snyman, Hwa Shi-Hsia, Daniel Muema, Farina Karim, Yashica Ganga, Abigail Ngoepe, Yenzekile Zungu, Inbal Gazy, Mallory Bernstein, Khadija Khan, Matilda Mazibuko, Ntombifuthi Mthabela, Dirhona Ramjit, null null, Oliver Limbo, Joseph Jardine, Devin Sok, Ian A Wilson, Willem Hanekom, Alex Sigal, Henrik Kløverpris, Thumbi Ndung'u, Alasdair Leslie
HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway. eLife 11 (2022)
Khadija Khan, Farina Karim, Sandile Cele, Kajal Reedoy, James Emmanuel San, Gila Lustig, Houriiyah Tegally, Yuval Rosenberg, Mallory Bernstein, Zesuliwe Jule, Yashica Ganga, Nokuthula Ngcobo, Matilda Mazibuko, Ntombifuthi Mthabela, Zoey Mhlane, Nikiwe Mbatha, Yoliswa Miya, Jennifer Giandhari, Yajna Ramphal, Taryn Naidoo, Aida Sivro, Natasha Samsunder, Ayesha B M Kharsany, Daniel Amoako, Jinal N Bhiman, Nithendra Manickchund, Quarraisha Abdool Karim, Nombulelo Magula, Salim S Abdool Karim, Glenda Gray, Willem Hanekom, Anne von Gottberg, null null, Ron Milo, Bernadett I Gosnell, Richard J Lessells, Penny L Moore, Tulio de Oliveira, Mahomed-Yunus S Moosa, Alex Sigal
Omicron infection enhances Delta antibody immunity in vaccinated persons. Nature 607 (7918) (2022)
Alex Sigal
Milder disease with Omicron: is it the virus or the pre-existing immunity? Nature reviews. Immunology 22 (2) (2022)
Allison J Greaney, Tyler N Starr, Rachel T Eguia, Andrea N Loes, Khadija Khan, Farina Karim, Sandile Cele, John E Bowen, Jennifer K Logue, Davide Corti, David Veesler, Helen Y Chu, Alex Sigal, Jesse D Bloom
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. PLoS pathogens 18 (2) (2022)
Shi-Hsia Hwa, Jumari Snyman, Mallory Bernstein, Yashica Ganga, Sandile Cele, Daniel Muema, Chee Wah Tan, Khadija Khan, Farina Karim, Willem Hanekom, Leslie Bernstein, Stefan H E Kaufmann, Lin-Fa Wang, Thumbi Ndung'u, Alex Sigal
HIV viremia is associated with compromised SARS-CoV-2 Beta variant neutralization. The Journal of infectious diseases (2022)
Gordon Wells, Joel N Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj, Leon Y Perumal, Malcolm Matthew, Robert L Hunter, Hayden T Pacl, Jacelyn E Peabody Lever, Denise D Stanford, Satinder P Singh, Prachi Bajpai, Upender Manne, Paul V Benson, Steven M Rowe, Stephan le Roux, Alex Sigal, Muofhe Tshibalanganda, Carlyn Wells, Marion Javal, Mpumelelo Msimang, Threnesan Naidoo, Adrie J C Steyn
A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions. EMBO molecular medicine 14 (11) (2022)
Khadija Khan, Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy, Sandile Cele, Gila Lustig, Daniel Gyamfi Amoako, Nicole Wolter, Natasha Samsunder, Aida Sivro, James Emmanuel San, Jennifer Giandhari, Houriiyah Tegally, Sureshnee Pillay, Yeshnee Naidoo, Matilda Mazibuko, Yoliswa Miya, Nokuthula Ngcobo, Nithendra Manickchund, Nombulelo Magula, Quarraisha Abdool Karim, Anne von Gottberg, Salim S Abdool Karim, Willem Hanekom, Bernadett I Gosnell, null null, Richard J Lessells, Tulio de Oliveira, Mahomed-Yunus S Moosa, Alex Sigal
Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nature communications 13 (1) (2022)
Allison J Greaney, Tyler N Starr, Rachel T Eguia, Andrea N Loes, Khadija Khan, Farina Karim, Sandile Cele, John E Bowen, Jennifer K Logue, Davide Corti, David J Veesler, Helen Y Chu, Alex Sigal, Jesse D Bloom
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. bioRxiv : the preprint server for biology (2021)
Sandile Cele, Inbal Gazy, Laurelle Jackson, Shi-Hsia Hwa, Houriiyah Tegally, Gila Lustig, Jennifer Giandhari, Sureshnee Pillay, Eduan Wilkinson, Yeshnee Naidoo, Farina Karim, Yashica Ganga, Khadija Khan, Mallory Bernstein, Alejandro B Balazs, Bernadett I Gosnell, Willem Hanekom, Mahomed-Yunus S Moosa, null null, null null, Richard J Lessells, Tulio de Oliveira, Alex Sigal
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma. Nature 593 (7857) (2021)
Nikhil Faulkner, Kevin W Ng, Mary Y Wu, Ruth Harvey, Marios Margaritis, Stavroula Paraskevopoulou, Catherine Houlihan, Saira Hussain, Maria Greco, William Bolland, Scott Warchal, Judith Heaney, Hannah Rickman, Moria Spyer, Daniel Frampton, Matthew Byott, Tulio de Oliveira, Alex Sigal, Svend Kjær, Charles Swanton, Sonia Gandhi, Rupert C L Beale, Steve J Gamblin, John W McCauley, Rodney Stuart Daniels, Michael Howell, David Bauer, Eleni Nastouli, George Kassiotis
Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains. eLife 10 (2021)
Sandile Cele, Laurelle Jackson, David S Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally, James Emmanuel San, Deborah Cromer, Cathrine Scheepers, Daniel G Amoako, Farina Karim, Mallory Bernstein, Gila Lustig, Derseree Archary, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Shi-Hsia Hwa, Jennifer Giandhari, Jonathan Michael Blackburn, Bernadett I Gosnell, Salim S Abdool Karim, Willem Hanekom, null null, null null, Anne von Gottberg, Jinal N Bhiman, Richard J Lessells, Mahomed-Yunus S Moosa, Miles P Davenport, Tulio de Oliveira, Penny L Moore, Alex Sigal
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization. Nature 602 (7898) (2021)
Farina Karim, Inbal Gazy, Sandile Cele, Yenzekile Zungu, Robert Krause, Mallory Bernstein, Khadija Khan, Yashica Ganga, Hylton Errol Rodel, Ntombifuthi Mthabela, Matilda Mazibuko, Daniel Muema, Dirhona Ramjit, Thumbi Ndung'u, Willem Hanekom, Bernadett Gosnell, Richard J Lessells, Emily B Wong, Tulio de Oliveira, Yunus Moosa, Gil Lustig, Alasdair Leslie, Henrik Kløverpris, Alex Sigal
HIV status alters disease severity and immune cell responses in beta variant SARS-CoV-2 infection wave. eLife 10 (2021)
Gila Lustig, Sandile Cele, Farina Karim, Anne Derache, Abigail Ngoepe, Khadija Khan, Bernadett I Gosnell, Mahomed-Yunus S Moosa, Ntombi Ntshuba, Suzaan Marais, Prakash M Jeena, Katya Govender, John Adamson, Henrik Kløverpris, Ravindra Kumar Gupta, Rohen Harrichandparsad, Vinod B Patel, Alex Sigal
T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy. PLoS pathogens 17 (9) (2021)
Khadija Khan, Gila Lustig, Mallory Bernstein, Derseree Archary, Sandile Cele, Farina Karim, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Yoliswa Miya, Ntombifuthi Mthabela, Nombulelo P Magula, Richard Lessells, Tulio de Oliveira, Bernadett I Gosnell, Salim Abdool Karim, Nigel Garrett, Willem Hanekom, Linda Gail-Bekker, Glenda Gray, Jonathan M Blackburn, Mahomed-Yunus S Moosa, Alex Sigal, null null
Immunogenicity of SARS-CoV-2 infection and Ad26.CoV2.S vaccination in people living with HIV. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Ana Moyano, Gila Lustig, Hylton E Rodel, Tibor Antal, Alex Sigal
Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition. PLoS computational biology 16 (2) (2020)
Laurelle Jackson, Jessica Hunter, Sandile Cele, Isabella Markham Ferreira, Andrew C Young, Farina Karim, Rajhmun Madansein, Kaylesh J Dullabh, Chih-Yuan Chen, Noel J Buckels, Yashica Ganga, Khadija Khan, Mikael Boulle, Gila Lustig, Richard A Neher, Alex Sigal
Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. eLife 7 (2018)
Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal
Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. eLife 6 (2017)
Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal
Correction: Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. eLife 6 (2017)
Mikaël Boullé, Thorsten G Müller, Sabrina Dähling, Yashica Ganga, Laurelle Jackson, Deeqa Mahamed, Lance Oom, Gila Lustig, Richard A Neher, Alex Sigal
HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell. PLoS pathogens 12 (11) (2016)

Alex Sigal.css-eqlu8i{font-size:small;padding-left:4px;} (A Sigal)

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Alex Sigal (A Sigal)