Alexandre Orthwein

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 11

Top Venues

McGill University Department of Oncology

Université de Montreal Département de microbiologie et immunologie (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

McGill University Department of Oncology Jan 01 2016

Canada

Principal Investigator/Assistant Professor :: Lady Davis Institute - Jewish General Hospital

Mount Sinai Hospital Feb 28 2012 - Jan 01 2016

Canada

Postdoctoral Fellow :: Lunenfeld-Tanenbaum Research Institute (Dr. Daniel Durocher)

Education History

Université de Montreal Département de microbiologie et immunologie Apr 01 2007 - Apr 01 2012

Canada

PHD

Université de Montreal Département de microbiologie et immunologie Sep 01 2005 - Apr 01 2007

Canada

MSC

Université de Strasbourg Sep 01 2001 - Jun 01 2005

France

BSC

Publications

Yang Shen, Erin Connolly, Meili Aiello, Chengjing Zhou, Prasanthi Chappa, Haorui Song, Patan Tippitak, Tarralyn Clark, Maria Andrea Cardenas, Nataliya Prokhnevska, Annapaola Mariniello, Meghana S Pagadala, Vishal R Dhere, Sarwish Rafiq, Aparna H Kesarwala, Alexandre Orthwein, Susan N Thomas, Mohammad K Khan, J Brandon Dixon, Gregory B Lesinski, Michael C Lowe, Haydn T Kissick, David S Yu, Chrystal M Paulos, Nicole C Schmitt, Zachary S Buchwald
Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node. Research square (2024)
John J Heath, Caitlynn Mirabelli, Matthew G Annis, Valerie Sabourin, Steven Hébert, Steven Findlay, HaEun Kim, Michael Witcher, Claudia L Kleinman, Peter M Siegel, Alexandre Orthwein, Josie Ursini-Siegel
The Neurodevelopmental Protein POGZ Suppresses Metastasis in Triple Negative Breast Cancer by Attenuating TGFβ Signaling. Cancer research (2024)
Zachary Buchwald, Yang Shen, Erin Connolly, Meili Aiello, Chengjing Zhou, Prasanthi Chappa, Haorui Song, Patan Tippitak, Tarralyn Clark, Maria Andrea Cardenas, Nataliya Prokhnevska, Annapaola Mariniello, Meghana Pagadala, Vishal Dhere, Sarwish Rafiq, Aparna H Kesarwala, Alexandre Orthwein, Susan Thomas, Mohammad Khan, J Brandon Dixon, Gregory B Lesinski, Michael C Lowe, Haydn T Kissick, David Yu, Chrystal M Paulos, Nicole C Schmitt
Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node. Research square (2024)
Zachary Buchwald, Yang Shen, Erin Connolly, Meili Aiello, Chengjing Zhou, Prasanthi Chappa, Haorui Song, Patan Tippitak, Tarralyn Clark, Maria Andrea Cardenas, Nataliya Prokhnevska, Annapaola Mariniello, Meghana Pagadala, Vishal Dhere, Sarwish Rafiq, Aparna H Kesarwala, Alexandre Orthwein, Susan Thomas, Mohammad Khan, J Brandon Dixon, Gregory B Lesinski, Michael C Lowe, Haydn T Kissick, David Yu, Chrystal M Paulos, Nicole C Schmitt
Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node. Research square (2024)
Edgar Pinedo-Carpio, Julien Dessapt, Adèle Beneyton, Lauralicia Sacre, Marie-Anne Bérubé, Romain Villot, Elise G Lavoie, Yan Coulombe, Andréanne Blondeau, Jonathan Boulais, Abba Malina, Vincent M Luo, Anna-Maria Lazaratos, Jean-François Coté, Frédérick A Mallette, Alba Guarné, Jean-Yves Masson, Amelie Fradet-Turcotte, Alexandre Orthwein
FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair. Science advances 9 (32) (2023)
Dana Sherill-Rofe, Oded Raban, Steven Findlay, Dolev Rahat, Irene Unterman, Arash Samiei, Amber Yasmeen, Zafir Kaiser, Hellen Kuasne, Morag Park, William D Foulkes, Idit Bloch, Aviad Zick, Walter H Gotlieb, Yuval Tabach, Alexandre Orthwein
Multi-omics data integration analysis identifies the spliceosome as a key regulator of DNA double-strand break repair. NAR cancer 4 (2) (2022)
Francois Emile Mercier, Jiantao Shi, David Brian Sykes, Toshihiko Oki, Maja Jankovic, Cheuk-Him Man, Youmna S Kfoury, Elizabeth Miller, Shutao He, Alexander Zhu, Radovan Vasic, John G Doench, Alexandre Orthwein, Franziska Michor, David T Scadden
In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies. Blood advances 6 (17) (2022)
Estelle Simo Cheyou, Jacopo Boni, Jonathan Boulais, Edgar Pinedo-Carpio, Abba Malina, Dana Sherill-Rofe, Vincent M Luo, Christophe Goncalves, Halil Bagci, Alexandra Maters, Raquel Cuella-Martin, Yuval Tabach, Sonia Del Rincon, Jean-Francois Côté, Barbara Rivera, Alexandre Orthwein
Systematic proximal mapping of the classical RAD51 paralogs unravel functionally and clinically relevant interactors for genome stability. PLoS genetics 18 (11) (2022)
John Heath, Estelle Simo Cheyou, Steven Findlay, Vincent M Luo, Edgar Pinedo Carpio, Jeesan Lee, Billel Djerir, Xiaoru Chen, Théo Morin, Benjamin Lebeau, Martin Karam, Halil Bagci, Damien Grapton, Josie Ursini-Siegel, Jean-Francois Côté, Michael Witcher, Stéphane Richard, Alexandre Maréchal, Alexandre Orthwein
POGZ promotes homology-directed DNA repair in an HP1-dependent manner. EMBO reports (2021)
Jacopo Boni, Aida Idani, Carla Roca, Lidia Feliubadaló, Eva Tomiak, Evan Weber, William D Foulkes, Alexandre Orthwein, Zaki El Haffaf, Conxi Lazaro Garcia, Barbara Rivera
A decade of RAD51C and RAD51D germline variants in cancer. Human mutation 43 (3) (2021)
Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle Simo-Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Elise G Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K Mann, Kathleen Oros Klein, Celia M Greenwood, Yuval Tabach, Morag Park, Jean-François Coté, Jean-Yves Masson, Alexandre Maréchal, Alexandre Orthwein
SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. The EMBO journal 37 (18) (2018)

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Publication Activity (10 Years)

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Alexandre Orthwein