David Brian Sykes (David B Sykes, David A W Sykes)

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 34

Top Topics

Acute Myeloid Leukemia

Gene Expression

Fluorescence Imaging

Top Venues

Nature communications

Operative neurosurgery (Hagerstown, Md.)

The New England journal of medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Kiranj Chaudagar, Hanna M Hieromnimon, Rimpi Khurana, Brian Labadie, Taghreed Hirz, Shenglin Mei, Raisa Hasan, Jordan S Shafran, Anne Kelley, Eva Apostolov, Ghamdan Al-Eryani, Kate Harvey, Srikrishnan Rameshbabu, Mayme Loyd, Kaela M Bynoe, Catherine Drovetsky, Solanki Aniruddhsingh, Erica Markiewicz, Marta Zamora, Xiaobing Fan, Stephan C Schürer, Alexander Swarbrick, David Brian Sykes, Akash Patnaik
Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Manqi Zhang, Yasemin Ceyhan, Shenglin Mei, Taghreed Hirz, David Brian Sykes, Irina U Agoulnik
Regulation of EZH2 Expression by INPP4B in Normal Prostate and Primary Prostate Cancer. Cancers 15 (22) (2023)
Anastasiia Petenkova, Shelby A Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To, Jelena Milosevic, Rana Barghout, Abirami Kugadas, Xiaoxiao Lu, Jennifer Geddes-McAlister, Raina Fichorova, David Brian Sykes, Mark D Distefano, Mihaela Gadjeva
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature communications 14 (1) (2023)
Anastasiia Petenkova, Shelby A Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To, Jelena Milosevic, Rana Barghout, Abirami Kugadas, Xiaoxiao Lu, Jennifer Geddes-McAlister, Raina Fichorova, David Brian Sykes, Mark D Distefano, Mihaela Gadjeva
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature communications 14 (1) (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Youmna S Kfoury, Fei Ji, Esha Jain, Michael C Mazzola, David T Scadden, Ani Papazian, Francois Emile Mercier, David Brian Sykes, Anna Kiem, Mark A Randolph, Omar I Abdel-Wahab, Laura Maria Calvi, Ruslan Sadreyev, David T Scadden
The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression. Blood advances (2023)
Anastasiia Petenkova, Shelby A Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To, Jelena Milosevic, Rana Barghout, Abirami Kugadas, Xiaoxiao Lu, Jennifer Geddes-McAlister, Raina Fichorova, David Brian Sykes, Mark D Distefano, Mihaela Gadjeva
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature communications 14 (1) (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Amy N Sexauer, Gabriela Alexe, Karin Gustafsson, Elizabeth Zanetakos, Jelena Milosevic, Mary L Ayres, Varsha Gandhi, Yana Pikman, Kimberly Stegmaier, David Brian Sykes
DHODH: A promising target in the treatment of T-Acute Lymphoblastic Leukemia. Blood advances (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Catherine Rhee, Elizabeth W Scadden, Lai Ping Wong, David T Scadden, Michael C Mazzola, Phillip L Chea, Hiroki Kato, Friedrich F Hoyer, Meeta Mistry, Bum-Kyu Lee, Jonghwan Kim, Matthias Nahrendorf, Michael K Mansour, David Brian Sykes, Ruslan Sadreyev, David T Scadden
Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors. Blood (2023)
Eitan Kugler, Shreyas Madiwale, Darren Yong, Julie A I Thoms, Yehudit Birger, David Brian Sykes, Johannes Schmoellerl, Aneta Drakul, Valdemar Priebe, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei David Chen, Brian Raught, Qiao Liu, Heather Ogana, Elisabeth Liedke, Jean-Pierre Bourquin, Johannes Zuber, Michael Milyavsky, John E Pimanda, Gilbert G Privé, Shai Izraeli
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG. Nature communications 14 (1) (2023)
Troy Q Tabarestani, David Brian Sykes, Gisselle Maquoit, Timothy Y Wang, Chakib M Ayoub, Christopher I Shaffrey, Walter F Wiggins, Muhammad M Abd-El-Barr
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative neurosurgery (Hagerstown, Md.) 24 (3) (2022)
Troy Q Tabarestani, David Brian Sykes, Gisselle Maquoit, Timothy Y Wang, Chakib M Ayoub, Christopher I Shaffrey, Walter F Wiggins, Muhammad M Abd-El-Barr
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative neurosurgery (Hagerstown, Md.) 24 (3) (2022)
Jina Ko, Martin Wilkovitsch, Juhyun Oh, Rainer H Kohler, Evangelia Bolli, Mikaël J Pittet, Claudio Vinegoni, David Brian Sykes, Hannes Mikula, Ralph Weissleder, Jonathan C T Carlson
Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes. Nature biotechnology 40 (11) (2022)
Troy Q Tabarestani, David Brian Sykes, Gisselle Maquoit, Timothy Y Wang, Chakib M Ayoub, Christopher I Shaffrey, Walter F Wiggins, Muhammad M Abd-El-Barr
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative neurosurgery (Hagerstown, Md.) 24 (3) (2022)
Troy Q Tabarestani, David Brian Sykes, Gisselle Maquoit, Timothy Y Wang, Chakib M Ayoub, Christopher I Shaffrey, Walter F Wiggins, Muhammad M Abd-El-Barr
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative neurosurgery (Hagerstown, Md.) 24 (3) (2022)
Adam L Viens, Kyle D Timmer, Natalie J Alexander, Rana Barghout, Jelena Milosevic, Alex Hopke, Natalie J Atallah, Allison K Scherer, David Brian Sykes, Daniel Irima, Michael K Mansour
TLR Signaling Rescues Fungicidal Activity in Syk-Deficient Neutrophils. Journal of immunology (Baltimore, Md. : 1950) 208 (7) (2022)
Troy Q Tabarestani, David Brian Sykes, Gisselle Maquoit, Timothy Y Wang, Chakib M Ayoub, Christopher I Shaffrey, Walter F Wiggins, Muhammad M Abd-El-Barr
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative neurosurgery (Hagerstown, Md.) (2022)
Francois Emile Mercier, Jiantao Shi, David Brian Sykes, Toshihiko Oki, Maja Jankovic, Cheuk-Him Man, Youmna S Kfoury, Elizabeth Miller, Shutao He, Alexander Zhu, Radovan Vasic, John G Doench, Alexandre Orthwein, Franziska Michor, David T Scadden
In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies. Blood advances 6 (17) (2022)
Zhengping Huang, Xiaomeng You, Liang Chen, Yan Du, Kailey Brodeur, Hyuk Jee, Qiang Wang, Grace Linder, Roxane Darbousset, Pierre Cunin, Margaret H Chang, Alexandra Wactor, Brian M Wauford, Marc J C Todd, Kevin Wei, Ying Li, Anais Levescot, Yoichiro Iwakura, Virginia M Pascual, Nicole E Baldwin, Pierre Quartier, Tianwang Li, Maria T Gianatasio, Robert P Hasserjian, Lauren A Henderson, David Brian Sykes, Elizabeth D Mellins, Scott W Canna, Julia Forgan-Farnam Charles, Peter A Nigrovic, Pui Y Lee
mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Nature communications 13 (1) (2022)
Troy Q Tabarestani, David Brian Sykes, Gisselle Maquoit, Timothy Y Wang, Chakib M Ayoub, Christopher I Shaffrey, Walter F Wiggins, Muhammad M Abd-El-Barr
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative neurosurgery (Hagerstown, Md.) (2022)
Christa Haase, Karin Gustafsson, Shenglin Mei, Shu-Chi A Yeh, Dmitry Richter, Jelena Milosevic, Raphaël Turcotte, Peter V Kharchenko, David Brian Sykes, David T Scadden, Charles P Lin
Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging. Nature methods 19 (12) (2022)
Jihee Sohn, Jelena Milosevic, Thomas Brouse, Najihah Aziz, Jenna Elkhoury, Suya Wang, Alexander Hauschild, Nick van Gastel, Murat Cetinbas, Sara F Tufa, Douglas R Keene, Ruslan I Sadreyev, William T Pu, David Brian Sykes
A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis. Blood advances 6 (8) (2022)
Adele M Alchahin, Shenglin Mei, Ioanna Tsea, Taghreed Hirz, Youmna Kfoury, Douglas Dahl, Chin-Lee Wu, Alexander O Subtelny, Shulin Wu, David T Scadden, John H Shin, Philip J Saylor, David Brian Sykes, Peter V Kharchenko, Ninib Baryawno
A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma. Nature communications 13 (1) (2022)
Allison K Scherer, Alex Hopke, David Brian Sykes, Daniel Irimia, Michael K Mansour
Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities? PLoS pathogens 17 (7) (2021)
Fangxue Yan, Jinyang Li, Jelena Milosevic, Ricardo Petroni, Suying Liu, Zhennan Shi, Salina Yuan, Janice M Reynaga, Yuwei Qi, Joshua Rico, Sixiang Yu, Yiman Liu, Susumu Rokudai, Neil Palmisiano, Sara E Meyer, Pamela J Sung, Liling Wan, Fei Lan, Benjamin A Garcia, Ben Z Stanger, David Brian Sykes, M Andres Blanco
KAT6A and ENL form an epigenetic transcriptional control module to drive critical leukemogenic gene expression programs. Cancer discovery (2021)
David Brian Sykes, Eric W Zhang, Rebecca S Karp Leaf, Valentina Nardi, Sarah E Turbett
Case 10-2020: An 83-Year-Old Man with Pancytopenia and Acute Renal Failure. The New England journal of medicine 382 (13) (2020)
Michael Mann, Tania Kreuzbauer, David Brian Sykes
A man with polycythemia vera, myelodysplastic syndrome and acquired microcytosis. BMJ case reports 12 (8) (2019)
J Scott Fites, Michael Gui, John F Kernien, Paige Negoro, Zeina Dagher, David Brian Sykes, Jeniel E Nett, Michael K Mansour, Bruce S Klein
An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections. PLoS pathogens 14 (5) (2018)
Shuying Xu, Marianela Feliu, Allison K Lord, Daniel P Lukason, Paige E Negoro, Nida S Khan, Zeina Dagher, Michael B Feldman, Jennifer L Reedy, Samantha N Steiger, Jenny M Tam, Alexander A Soukas, David Brian Sykes, Michael K Mansour
Biguanides enhance antifungal activity against Candida glabrata. Virulence 9 (1) (2018)
David Brian Sykes, Wilfried Schroyens
Complete Responses in the TEMPI Syndrome after Treatment with Daratumumab. The New England journal of medicine 378 (23) (2018)
David Brian Sykes
The emergence of dihydroorotate dehydrogenase (DHODH) as a therapeutic target in acute myeloid leukemia. Expert opinion on therapeutic targets 22 (11) (2018)