Alexis L Rohou (Alexis Rohou)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 27

Top Topics

Structural Basis

Chronic Lymphocytic Leukemia

Age Related Macular Degeneration

Top Venues

Bioconjugate chemistry

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Whitney Shatz, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis L Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar N Kalia
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40. Bioconjugate chemistry 35 (5) (2024)
Whitney Shatz, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis L Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar N Kalia
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40. Bioconjugate chemistry 35 (5) (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ (2024)
Jennifer E Kung, Matthew C Johnson, Christine C Jao, Christopher P Arthur, Dimitry Tegunov, Alexis L Rohou, Jawahar Sudhamsu
Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM. bioRxiv : the preprint server for biology (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Whitney Shatz, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis L Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar N Kalia
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40. Bioconjugate chemistry (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods 21 (7) (2024)
Whitney Shatz, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis L Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar N Kalia
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40. Bioconjugate chemistry 35 (5) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods 21 (7) (2024)
Jennifer E Kung, Matthew C Johnson, Christine C Jao, Christopher P Arthur, Dimitry Tegunov, Alexis L Rohou, Jawahar Sudhamsu
Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM. bioRxiv : the preprint server for biology (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods (2024)
Jennifer E Kung, Matthew C Johnson, Christine C Jao, Christopher P Arthur, Dimitry Tegunov, Alexis L Rohou, Jawahar Sudhamsu
Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM. bioRxiv : the preprint server for biology (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods 21 (7) (2024)
Whitney Shatz, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis L Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar N Kalia
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40. Bioconjugate chemistry 35 (5) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods (2024)
Marc Kschonsak, Matthew C Johnson, Rachel Schelling, Evan M Green, Lionel Rougé, Hoangdung Ho, Nidhi Patel, Cem Kilic, Edward Kraft, Christopher P Arthur, Alexis L Rohou, Laetitia Comps-Agrar, Nadia Martinez-Martin, Laurent Perez, Jian Payandeh, Claudio Ciferri
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Science advances 8 (10) (2022)
Stefan Gerhardy, Mark Ultsch, Wanjian Tang, Evan Green, Jeffrey K Holden, Wei Li, Alberto Estevez, Chris Arthur, Irene Tom, Alexis L Rohou, Daniel Kirchhofer
Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration. Nature communications 13 (1) (2022)
Alexis L Rohou
Improving cryo-EM structure validation. Nature methods 18 (2) (2021)
Lionel Rougé, Nancy Chiang, Micah Steffek, Christine Kugel, Tristan I Croll, Christine Tam, Alberto Estevez, Christopher P Arthur, Christopher M M Koth, Claudio Ciferri, Edward Kraft, Jian Payandeh, Gerald Nakamura, James T Koerber, Alexis L Rohou
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab. Science (New York, N.Y.) 367 (6483) (2020)
Thomas Clairfeuille, Alexander Cloake, Daniel T Infield, José P Llongueras, Christopher P Arthur, Zhong Rong Li, Yuwen Jian, Marie-France Martin-Eauclaire, Pierre E Bougis, Claudio Ciferri, Christopher A Ahern, Frank Bosmans, David H Hackos, Alexis L Rohou, Jian Payandeh
Structural basis of α-scorpion toxin action on Nav channels. Science (New York, N.Y.) 363 (6433) (2019)
Michael J Holliday, Axel Witt, Alejandro Rodríguez Gama, Benjamin T Walters, Christopher P Arthur, Randal Halfmann, Alexis L Rohou, Erin C Dueber, Wayne J Fairbrother
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation. Nature communications 10 (1) (2019)
Michael J Holliday, Ryan Ferrao, Gladys de Leon Boenig, Alberto Estevez, Elizabeth Helgason, Alexis L Rohou, Erin C Dueber, Wayne J Fairbrother
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. The Journal of biological chemistry 293 (43) (2018)
Timothy Grant, Alexis L Rohou, Nikolaus Grigorieff
cisTEM, user-friendly software for single-particle image processing. eLife 7 (2018)
Anna Zhou, Alexis L Rohou, Daniel G Schep, John V Bason, Martin G Montgomery, John E Walker, Nikolaus Grigorieff, John L Rubinstein
Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. eLife 4 (2015)