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Wah Chiu

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 57

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Nature methods

bioRxiv : the preprint server for biology

Stanford University

University of California Berkeley (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stanford University Jul 1o 2017

United States

Professor :: Bioengineering

Education History

University of California Berkeley Sep 1o 1969 - Jun 1o 1975

United States

PHD :: Biophysics

Publications

Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
David Chmielewski, Eric A Wilson, Grigore Pintilie, Peng Zhao, Muyuan Chen, Michael F Schmid, Graham Simmons, Lance L Wells, Jing Jin, Abhishek Singharoy, Wah Chiu
Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans. Nature communications 14 (1) (2023)
Rachael C Kretsch, Ebbe Sloth Andersen, Janusz M Bujnicki, Wah Chiu, Rachel J Hagey, Bingnan Luo, Benoît Masquida, Ewan K S McRae, Griffin M Schroeder, Zhaoming Su, Joseph E Wedekind, Lily Xu, Kaiming Zhang, Ivan N Zheludev, John Moult, Andriy Kryshtafovych
RNA target highlights in CASP15: Evaluation of predicted models by structure providers. Proteins (2023)
Molly F Parsons, Matthew F Allan, Shanshan Li, Tyson R Shepherd, Sakul Ratanalert, Kaiming Zhang, Krista M Pullen, Wah Chiu, Silvi Rouskin, Mark Bathe
3D RNA-scaffolded wireframe origami. Nature communications 14 (1) (2023)
Molly F Parsons, Matthew F Allan, Shanshan Li, Tyson R Shepherd, Sakul Ratanalert, Kaiming Zhang, Krista M Pullen, Wah Chiu, Silvi Rouskin, Mark Bathe
3D RNA-scaffolded wireframe origami. Nature communications 14 (1) (2023)
Rahel A Woldeyes, Masataka Nishiga, Alison S Vander Roest, Leeya Engel, Prerna Giri, Gabrielle C Montenegro, Andrew C Wu, Alexander R Dunn, James A Spudich, Daniel Bernstein, Michael F Schmid, Joseph C Wu, Wah Chiu
Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context. bioRxiv : the preprint server for biology (2023)
Natasha K Dudek, Jesus G Galaz-Montoya, Handuo Shi, Megan Mayer, Cristina Danita, Arianna I Celis, Tobias Viehboeck, Gong-Her Wu, Barry Behr, Silvia Bulgheresi, Kerwyn Casey Huang, Wah Chiu, David A Relman
Previously uncharacterized rectangular bacterial structures in the dolphin mouth. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Muyuan Chen, Michael F Schmid, Wah Chiu
Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nature methods (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
David Chmielewski, Eric A Wilson, Grigore Pintilie, Peng Zhao, Muyuan Chen, Michael F Schmid, Graham Simmons, Lance L Wells, Jing Jin, Abhishek Singharoy, Wah Chiu
Integrated analyses reveal a hinge glycan regulates coronavirus spike tilting and virus infectivity. Research square (2023)
Molly F Parsons, Matthew F Allan, Shanshan Li, Tyson R Shepherd, Sakul Ratanalert, Kaiming Zhang, Krista M Pullen, Wah Chiu, Silvi Rouskin, Mark Bathe
3D RNA-scaffolded wireframe origami. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
David Chmielewski, Eric A Wilson, Grigore Pintilie, Peng Zhao, Muyuan Chen, Michael F Schmid, Graham Simmons, Lance L Wells, Jing Jin, Abhishek Singharoy, Wah Chiu
Integrated analyses reveal a hinge glycan regulates coronavirus spike tilting and virus infectivity. Research square (2023)
Momei Zhou, Benjamin Vollmer, Emily A Machala, Muyuan Chen, Kay Grünewald, Ann M Arvin, Wah Chiu, Stefan L Oliver
Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states. Nature communications 14 (1) (2023)
Stella Y Sun, Yechiel Shai, Muyuan Chen, Grigore D Pintilie, Michael F Schmid, Steven J Ludtke, John C Boothroyd, Wah Chiu
Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proceedings of the National Academy of Sciences of the United States of America 119 (6) (2022)
Xiao Wang, Shanshan Li, Hyungmin Jun, Torsten John, Kaiming Zhang, Hannah Fowler, Jonathan P K Doye, Wah Chiu, Mark Bathe
Planar 2D wireframe DNA origami. Science advances 8 (20) (2022)
Shanshan Li, Michael Z Palo, Grigore Pintilie, Xiaojing Zhang, Zhaoming Su, Kalli Kappel, Wah Chiu, Kaiming Zhang, Rachel J Hagey
Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 119 (37) (2022)
Ze-Wen Zhang, Yuzhang Li, Rong Xu, Weijiang Zhou, Yanbin Li, Solomon T Oyakhire, Yecun Wu, Jinwei Xu, Hansen Wang, Zhiao Yu, David Thomas Boyle, William Huang, Yusheng Ye, Hao Chen, Jiayu Wan, Zhenan Bao, Wah Chiu, Yi Cui
Capturing the swelling of solid-electrolyte interphase in lithium metal batteries. Science (New York, N.Y.) 375 (6576) (2022)
David Chmielewski, Michael F Schmid, Graham Simmons, Jing Jin, Wah Chiu
Chikungunya virus assembly and budding visualized in situ using cryogenic electron tomography. Nature microbiology 7 (8) (2022)
Yechiel Shai, Peter D Dahlberg, Stella Y Sun, Daniël M Pelt, Chi Yong Kim, Elizabeth S Egan, James A Sethian, Wah Chiu, John C Boothroyd
Cryo-electron tomography with mixed-scale dense neural networks reveals key steps in deployment of Toxoplasma invasion machinery. PNAS nexus 1 (4) (2022)
Kaiming Zhang, Naoki Horikoshi, Shanshan Li, Alexander S Powers, Mikhail A Hameedi, Grigore D Pintilie, Hee-Don Chae, Yousuf A Khan, Carl-Mikael Suomivuori, Ron O Dror, Kathleen M Sakamoto, Wah Chiu, Soichi Wakatsuki
Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. ACS central science 8 (2) (2022)
Stephen K Burley, Helen M Berman, Wah Chiu, Wei Dai, Justin W Flatt, Brian P Hudson, Jason T Kaelber, Sagar D Khare, Arkadiusz W Kulczyk, Catherine L Lawson, Grigore D Pintilie, Andrej Sali, Brinda Vallat, John D Westbrook, Jasmine Y Young, Christine Zardecki
Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future. Biophysical reviews (2022)
Ugis Sarkans, Wah Chiu, Lucy M Collinson, Michele C Darrow, Jan Ellenberg, David Grünwald, Jean-Karim Hériché, Andrii Iudin, Gabriel G Martins, Terry Meehan, Kedar Narayan, Ardan Patwardhan, Matthew Robert Geoffrey Russell, Helen R Saibil, Caterina Strambio-De-Castillia, Jason R Swedlow, Christian Tischer, Virginie Uhlmann, Paul Verkade, Mary Barlow, Omer Ali Bayraktar, Ewan Birney, Cesare Catavitello, Christopher J Cawthorne, Stephan Wagner-Conrad, Elizabeth Duke, Perrine Paul-Gilloteaux, Emmanuel M Gustin, Maria Harkiolaki, Pasi Kankaanpää, Thomas Lemberger, Jo McEntyre, Josh Moore, Andrew W Nicholls, Shuichi Onami, Helen Parkinson, Maddy Parsons, Marina Romanchikova, Nicholas Sofroniew, Jim Swoger, Nadine Utz, Lennard M Voortman, Frances Wong, Peijun Zhang, Gerard J Kleywegt, Alvis Brazma
REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology. Nature methods 18 (12) (2022)
Dillon P Cogan, Kaiming Zhang, Xiuyuan Li, Shanshan Li, Grigore D Pintilie, Soung Hun Roh, Charles S Craik, Wah Chiu, Chaitan Khosla
Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science (New York, N.Y.) 374 (6568) (2021)
Catherine L Lawson, Andriy Kryshtafovych, Paul D Adams, Pavel V Afonine, Matthew L Baker, Benjamin A Barad, Paul S Bond, Tom Burnley, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kevin D Cowtan, Ken A Dill, Frank DiMaio, Daniel P Farrell, James S Fraser, Mark A Herzik, Soon Wen Hoh, Jie Hou, Li-Wei Hung, Maxim Igaev, Agnel-Praveen Joseph, Daisuke Kihara, Dilip Kumar, Sumit Mittal, Bohdan Monastyrskyy, Mateusz Olek, Colin M Palmer, Ardan Patwardhan, Alberto Perez, Jonas Pfab, Grigore D Pintilie, Jane S Richardson, Peter B Rosenthal, Daipayan Sarkar, Luisa U Schäfer, Michael F Schmid, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Genki Terashi, Thomas C Terwilliger, Andrea C Vaiana, Liguo Wang, Zhe Wang, Stephanie A Wankowicz, Christopher J Williams, Martyn D Winn, Tianqi Wu, Xiaodi Yu, Kaiming Zhang, Helen M Berman, Wah Chiu
Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge. Nature methods 18 (2) (2021)
Jonathan J Knowlton, Daniel Gestaut, Boxue Ma, Gwen M Taylor, Alpay Burak Seven, Alexander Leitner, Gregory J Wilson, Sreejesh Shanker, Nathan A Yates, B V Venkataram Prasad, Ruedi Aebersold, Wah Chiu, Judith Frydman, Terence S Dermody
Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proceedings of the National Academy of Sciences of the United States of America 118 (11) (2021)
Yanyan Zhao, Michael F Schmid, Judith Frydman, Wah Chiu
CryoEM reveals the stochastic nature of individual ATP binding events in a group II chaperonin. Nature communications 12 (1) (2021)
Kaiming Zhang, Ivan N Zheludev, Rachel J Hagey, Raphael Haslecker, Yixuan J Hou, Rachael Kretsch, Grigore D Pintilie, Ramya Rangan, Wipapat Kladwang, Shanshan Li, Marie Teng-Pei Wu, Edward A Pham, Claire Bernardin-Souibgui, Ralph S Baric, Timothy P Sheahan, Victoria D'Souza, Jeffrey S Glenn, Wah Chiu, Rachel J Hagey
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nature structural & molecular biology 28 (9) (2021)
Seyed-Fakhreddin Torabi, Yen-Lin Chen, Kaiming Zhang, Jimin Wang, Suzanne J DeGregorio, Anand T Vaidya, Zhaoming Su, Suzette A Pabit, Wah Chiu, Lois Pollack, Joan A Steitz
Structural analyses of an RNA stability element interacting with poly(A). Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Jesus G Galaz-Montoya, Sarah H Shahmoradian, Koning Shen, Judith Frydman, Wah Chiu
Cryo-electron tomography provides topological insights into mutant huntingtin exon 1 and polyQ aggregates. Communications biology 4 (1) (2021)
Zhaoming Su, Kaiming Zhang, Kalli Kappel, Shanshan Li, Michael Z Palo, Grigore D Pintilie, Ramya Rangan, Bingnan Luo, Yuquan Wei, Rachel J Hagey, Wah Chiu
Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. Nature 596 (7873) (2021)
Peter J Blanco Carcache, Sijin Guo, Hui Li, Kaiming Zhang, Congcong Xu, Wah Chiu, Peixuan Guo
Regulation of reversible conformational change, size switching, and immunomodulation of RNA nanocubes. RNA (New York, N.Y.) 27 (9) (2021)
Stefan L Oliver, Yi Xing, Dong-Hua Chen, Soung Hun Roh, Grigore D Pintilie, David A Bushnell, Marvin H Sommer, Edward Yang, Andrea Carfi, Wah Chiu, Ann M Arvin
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion. PLoS pathogens 17 (1) (2021)
Ze-Wen Zhang, Yi Cui, Rafael Vila, Yanbin Li, Wenbo Zhang, Weijiang Zhou, Wah Chiu, Yi Cui
Cryogenic Electron Microscopy for Energy Materials. Accounts of chemical research 54 (18) (2021)
Kaiming Zhang, Shanshan Li, Grigore D Pintilie, David Chmielewski, Michael F Schmid, Graham Simmons, Jing Jin, Wah Chiu
A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles. bioRxiv : the preprint server for biology (2020)
Kaiming Zhang, Shuo Wang, Shanshan Li, Yuwei Zhu, Grigore D Pintilie, Tung-Chung Mou, Michael F Schmid, Zhiwei Huang, Wah Chiu
Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Peter D Dahlberg, Saumya Saurabh, Annina M Sartor, Jiarui Wang, Patrick G Mitchell, Wah Chiu, Lucy Shapiro, W E Moerner
Cryogenic single-molecule fluorescence annotations for electron tomography reveal in situ organization of key proteins in Caulobacter. Proceedings of the National Academy of Sciences of the United States of America 117 (25) (2020)
Stefan L Oliver, Yi Xing, Dong-Hua Chen, Soung Hun Roh, Grigore D Pintilie, David A Bushnell, Marvin H Sommer, Edward Yang, Andrea Carfi, Wah Chiu, Ann M Arvin
A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation. Nature communications 11 (1) (2020)
Kalli Kappel, Kaiming Zhang, Zhaoming Su, Andrew M Watkins, Wipapat Kladwang, Shanshan Li, Grigore D Pintilie, Ved V Topkar, Ramya Rangan, Ivan N Zheludev, Joseph D Yesselman, Wah Chiu, Rachel J Hagey
Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nature methods 17 (7) (2020)
Soung Hun Roh, Mrinal Shekhar, Grigore D Pintilie, Christophe J Chipot, Stephan Wilkens, Abhishek Singharoy, Wah Chiu
Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of Vo complex. Science advances 6 (41) (2020)
Lisa Selzer, Zhaoming Su, Grigore D Pintilie, Wah Chiu, Karla Kirkegaard
Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer. PLoS biology 18 (9) (2020)
Rafael K Campos, Jing Jin, Grace H Rafael, Mervin Zhao, Lei Liao, Graham Simmons, Steven Chu, Scott C Weaver, Wah Chiu, Yi Cui
Decontamination of SARS-CoV-2 and Other RNA Viruses from N95 Level Meltblown Polypropylene Fabric Using Heat under Different Humidities. ACS nano 14 (10) (2020)
Grigore D Pintilie, Kaiming Zhang, Zhaoming Su, Shanshan Li, Michael F Schmid, Wah Chiu
Measurement of atom resolvability in cryo-EM maps with Q-scores. Nature methods 17 (3) (2020)
Sijin Guo, Mario Vieweger, Kaiming Zhang, Hongran Yin, Hongzhi Wang, Xin Li, Shanshan Li, Shuiying Hu, Alex Sparreboom, B Mark Evers, Yizhou Dong, Wah Chiu, Peixuan Guo
Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy. Nature communications 11 (1) (2020)
Kaiming Zhang, Shanshan Li, Grigore D Pintilie, David Chmielewski, Michael F Schmid, Graham Simmons, Jing Jin, Wah Chiu
A 3.4-Å cryo-electron microscopy structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles. QRB discovery 1 (2020)
Catherine L Lawson, Helen M Berman, Wah Chiu
Evolving data standards for cryo-EM structures. Structural dynamics (Melville, N.Y.) 7 (1) (2020)
Kaiming Zhang, Ivan N Zheludev, Rachel J Hagey, Marie Teng-Pei Wu, Raphael Haslecker, Yixuan J Hou, Rachael C Kretsch, Grigore D Pintilie, Ramya Rangan, Wipapat Kladwang, Shanshan Li, Edward A Pham, Claire Bernardin-Souibgui, Ralph S Baric, Timothy P Sheahan, Victoria D Souza, Jeffrey S Glenn, Wah Chiu, Rachel J Hagey
Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome. bioRxiv : the preprint server for biology (2020)
Yanbin Li, William Huang, Yuzhang Li, Wah Chiu, Yi Cui
Opportunities for Cryogenic Electron Microscopy in Materials Science and Nanoscience. ACS nano 14 (8) (2020)
Stefan L Oliver, Yi Xing, Dong-Hua Chen, Soung Hun Roh, Grigore D Pintilie, David A Bushnell, Marvin H Sommer, Edward Yang, Andrea Carfi, Wah Chiu, Ann M Arvin
Publisher Correction: A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation. Nature communications 11 (1) (2020)
Hye Ryoung Lee, Lei Liao, Wang Xiao, Arturas Vailionis, Antonio J Ricco, Robin White, Yoshio Nishi, Wah Chiu, Steven Chu, Yi Cui
Three-Dimensional Analysis of Particle Distribution on Filter Layers inside N95 Respirators by Deep Learning. Nano letters 21 (1) (2020)
Andriy Kryshtafovych, Sony Malhotra, Bohdan Monastyrskyy, Tristan Cragnolini, Agnel-Praveen Joseph, Wah Chiu, Andriy Kryshtafovych
Cryo-electron microscopy targets in CASP13: Overview and evaluation of results. Proteins 87 (12) (2019)
Kaiming Zhang, Huawei Zhang, Shanshan Li, Grigore D Pintilie, Tung-Chung Mou, Yuanzhu Gao, Qinfen Zhang, Henry van den Bedem, Michael F Schmid, Shannon Wing Ngor Au, Wah Chiu
Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution. Proceedings of the National Academy of Sciences of the United States of America 116 (14) (2019)
Xiang Lan, Zhaoming Su, Yadong Zhou, Travis A Meyer, Yonggang Ke, Qiangbin Wang, Wah Chiu, Na Liu, Shengli Zou, Hao Yan, Yan Liu
Programmable Supra-Assembly of a DNA Surface Adapter for Tunable Chiral Directional Self-Assembly of Gold Nanorods. Angewandte Chemie (International ed. in English) 56 (46) (2017)
Michele C Darrow, Yujin Zhang, Bertrand P Cinquin, Elizabeth A Smith, Rosanne Boudreau, Ryan H Rochat, Michael F Schmid, Yang Xia, Carolyn A Larabell, Wah Chiu
Visualizing red blood cell sickling and the effects of inhibition of sphingosine kinase 1 using soft X-ray tomography. Journal of cell science 129 (18) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Wah Chiu