Thomas L Blundell (Tom Blundell, T L Blundell, Tom L Blundell)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 45

Top Topics

Circulating Tumor

Top Venues

Nature structural & molecular biology

Research square

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Aaron Weimann, Adam M Dinan, Christopher Ruis, Audrey Bernut, Stéphane Pont, Karen P Brown, Judy Ryan, Lúcia Santos, Louise Ellison, Emem Ukor, Arun Prasad Pandurangan, Sina Krokowski, Thomas L Blundell, Martin Welch, Beth Blane, Kim Judge, Rachel Bousfield, Nicholas M Brown, Josephine M Bryant, Irena Kukavica-Ibrulj, Giordano Rampioni, Livia Leoni, Patrick T Harrison, Sharon J Peacock, Nicholas R Thomson, Jeff Gauthier, Joanne L Fothergill, Roger C Levesque, Julian Parkhill, R Andres Floto
Evolution and host-specific adaptation of Pseudomonas aeruginosa . Science (New York, N.Y.) 385 (6704) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore Pintilie, Stephen Burley, Jiri Cerny, Vincent Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael Prisant, Randy J Read, Jane S Richardson, Alexis Rohou, Bohdan Schneider, Benjamin Sellers, Chenghua Chao, Elizabeth Sourial, Chris Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel Moriarty, Andrew Muenks, Garib Murshudov, Robert Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar Pothula, Christopher Rowley, Daipayan Sarkar, Luisa Schäfer, Christopher Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea Vaiana, Sundeep Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen Berman, Wah Chiu
Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Research square (2024)
William J McCarthy, Sherine E Thomas, Tayo Olaleye, Jennifer A Boland, R Andres Floto, Glyn Williams, Thomas L Blundell, Anthony G Coyne, Chris Abell
A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling. Angewandte Chemie (International ed. in English) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods 21 (7) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Research square (2024)
Aaron Weimann, Adam M Dinan, Christopher Ruis, Audrey Bernut, Stéphane Pont, Karen P Brown, Judy Ryan, Lúcia Santos, Louise Ellison, Emem Ukor, Arun Prasad Pandurangan, Sina Krokowski, Thomas L Blundell, Martin Welch, Beth Blane, Kim Judge, Rachel Bousfield, Nicholas M Brown, Josephine M Bryant, Irena Kukavica-Ibrulj, Giordano Rampioni, Livia Leoni, Patrick T Harrison, Sharon J Peacock, Nicholas R Thomson, Jeff Gauthier, Joanne L Fothergill, Roger C Levesque, Julian Parkhill, R Andres Floto
Evolution and host-specific adaptation of Pseudomonas aeruginosa . Science (New York, N.Y.) 385 (6704) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods 21 (7) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Research square (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore Pintilie, Stephen Burley, Jiri Cerny, Vincent Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael Prisant, Randy J Read, Jane S Richardson, Alexis Rohou, Bohdan Schneider, Benjamin Sellers, Chenghua Chao, Elizabeth Sourial, Chris Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel Moriarty, Andrew Muenks, Garib Murshudov, Robert Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar Pothula, Christopher Rowley, Daipayan Sarkar, Luisa Schäfer, Christopher Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea Vaiana, Sundeep Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen Berman, Wah Chiu
Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Research square (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods 21 (7) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Research square (2024)
William J McCarthy, Sherine E Thomas, Tayo Olaleye, Jennifer A Boland, R Andres Floto, Glyn Williams, Thomas L Blundell, Anthony G Coyne, Chris Abell
A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling. Angewandte Chemie (International ed. in English) 63 (37) (2024)
Catherine L Lawson, Andriy Kryshtafovych, Grigore D Pintilie, Stephen K Burley, Jiri Cerny, Vincent B Chen, Paul Emsley, Alberto Gobbi, Andrzej Joachimiak, Sigrid Noreng, Michael G Prisant, Randy J Read, Jane S Richardson, Alexis L Rohou, Bohdan Schneider, Benjamin D Sellers, Chenghua Shao, Elizabeth Sourial, Chris I Williams, Christopher J Williams, Ying Yang, Venkat Abbaraju, Pavel V Afonine, Matthew L Baker, Paul S Bond, Thomas L Blundell, Tom Burnley, Arthur Campbell, Renzhi Cao, Jianlin Cheng, Grzegorz Chojnowski, Kathryn D Cowtan, Frank Dimaio, Reza Esmaeeli, Nabin Giri, Helmut Grubmüller, Soon Wen Hoh, Jie Hou, Corey F Hryc, Carola Hunte, Maxim Igaev, Agnel-Praveen Joseph, Wei-Chun Kao, Daisuke Kihara, Dilip Kumar, Lijun Lang, Sean Lin, Sai Raghavendra Maddhuri Venkata Subramaniya, Sumit Mittal, Arup Mondal, Nigel W Moriarty, Andrew Muenks, Garib N Murshudov, Robert A Nicholls, Mateusz Olek, Colin M Palmer, Alberto Perez, Emmi Pohjolainen, Karunakar R Pothula, Christopher N Rowley, Daipayan Sarkar, Luisa U Schäfer, Christopher J Schlicksup, Gunnar F Schröder, Mrinal Shekhar, Dong Si, Abhishek Singharoy, Oleg V Sobolev, Genki Terashi, Andrea C Vaiana, Sundeep C Vedithi, Jacob Verburgt, Xiao Wang, Rangana Warshamanage, Martyn David Winn, Simone Weyand, Keitaro Yamashita, Minglei Zhao, Michael F Schmid, Helen M Berman, Wah Chiu
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge. Nature methods (2024)
Murielle Seif-El-Dahan, Antonia Kefala-Stavridi, Philippe Frit, Steven W Hardwick, Dimitri Y Chirgadze, Taiana Maia De Oliviera, Sébastien Britton, Nadia Barboule, Madeleine Bossaert, Arun Prasad Pandurangan, Katheryn Meek, Thomas L Blundell, Virginie Ropars, Patrick Calsou, Jean Baptiste Charbonnier, Amanda K Chaplin
PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Science advances 9 (22) (2023)
Christopher J Buehl, Noah J Goff, Mariia Mikhova, Steven W Hardwick, Thomas L Blundell, Mauro Modesti, Jens C Schmidt, Amanda K Chaplin, Katheryn Meek
Unravelling the complexities of DNA-PK activation by structure-based mutagenesis. Research square (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (17) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (17) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology (2023)
Katheryn Meek, Christopher Buehl, Noah Goff, Mariia Mikhova, Steven W Hardwick, Thomas L Blundell, Mauro Modesti, Jens Schmidt, Amanda K Chaplin
Unravelling the complexities of DNA-PK activation by structure-based mutagenesis. Research square (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (International ed. in English) (2023)
Katheryn Meek, Christopher Buehl, Noah Goff, Mariia Mikhova, Steven W Hardwick, Thomas L Blundell, Mauro Modesti, Jens Schmidt, Amanda K Chaplin
Unravelling the complexities of DNA-PK activation by structure-based mutagenesis. Research square (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Christopher J Buehl, Noah J Goff, Mariia Mikhova, Steven W Hardwick, Thomas L Blundell, Mauro Modesti, Jens C Schmidt, Amanda K Chaplin, Katheryn Meek
Unravelling the complexities of DNA-PK activation by structure-based mutagenesis. Research square (2023)
Christopher Ruis, Aaron Weimann, Gerry Tonkin-Hill, Arun Prasad Pandurangan, Marta Matuszewska, Gemma G R Murray, Roger C Levesque, Thomas L Blundell, R Andres Floto, Julian Parkhill
Mutational spectra are associated with bacterial niche. Nature communications 14 (1) (2023)
Shikang Liang, Thomas L Blundell
Human DNA-dependent protein kinase activation mechanism. Nature structural & molecular biology 30 (2) (2023)
Christopher J Buehl, Noah J Goff, Mariia Mikhova, Steven W Hardwick, Thomas L Blundell, Mauro Modesti, Jens C Schmidt, Amanda K Chaplin, Katheryn Meek
Unravelling the complexities of DNA-PK activation by structure-based mutagenesis. Research square (2023)
Martin Bartas, Kristyna Slychko, Václav Brázda, Jiří Červeň, Christopher A Beaudoin, Thomas L Blundell, Petr Pečinka
Searching for New Z-DNA/Z-RNA Binding Proteins Based on Structural Similarity to Experimentally Validated Zα Domain. International journal of molecular sciences 23 (2) (2022)
Shikang Liang, Sherine E Thomas, Amanda K Chaplin, Steven W Hardwick, Dimitri Y Chirgadze, Thomas L Blundell
Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. Nature 601 (7894) (2022)
Vitor Mendes, Simon R Green, Joanna C Evans, Jeannine Hess, Michal Blaszczyk, Christina Spry, Owain Bryant, James Cory-Wright, Daniel S-H Chan, Pedro H M Torres, Zhe Wang, Navid Nahiyaan, Sandra O'Neill, Sebastian Damerow, John Post, Tracy Bayliss, Sasha L Lynch, Anthony G Coyne, Peter C Ray, Chris Abell, Kyu Y Rhee, Helena I M Boshoff, Clifton Earl Barry, Valerie Mizrahi, Paul G Wyatt, Thomas L Blundell
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nature communications 12 (1) (2021)
Josephine M Bryant, Karen P Brown, Sophie Burbaud, Isobel Everall, Juan Manuel Belardinelli, Daniela Rodriguez-Rincon, Dorothy M Grogono, Chelsea M Peterson, Deepshikha Verma, Ieuan E S Evans, Christopher Ruis, Aaron Weimann, Divya Arora, Sony Malhotra, Bridget P Bannerman, Charlotte Passemar, Kerra Templeton, Gordon MacGregor, Kasim Jiwa, Andrew J Fisher, Thomas L Blundell, Diane J Ordway, Mary Jackson, Julian Parkhill, R Andres Floto
Stepwise pathogenic evolution of Mycobacterium abscessus. Science (New York, N.Y.) 372 (6541) (2021)
Octav Caldararu, Thomas L Blundell, Kasper P Kepp
A base measure of precision for protein stability predictors: structural sensitivity. BMC bioinformatics 22 (1) (2021)
Amanda K Chaplin, Steven W Hardwick, Shikang Liang, Antonia Kefala Stavridi, Ales Hnizda, Lee R Cooper, Taiana Maia De Oliveira, Dimitri Y Chirgadze, Thomas L Blundell
Dimers of DNA-PK create a stage for DNA double-strand break repair. Nature structural & molecular biology 28 (1) (2020)
Arun Prasad Pandurangan, Thomas L Blundell
Prediction of impacts of mutations on protein structure and interactions: SDM, a statistical approach, and mCSM, using machine learning. Protein science : a publication of the Protein Society 29 (1) (2019)
Asma Munir, Narender Kumar, Suresh Babu Ramalingam, Sembulingam Tamilzhalagan, Siva Kumar Shanmugam, Alangudi Natarajan Palaniappan, Dina Nair, Padma Priyadarshini, Mohan Natarajan, Srikanth Tripathy, Uma Devi Ranganathan, Sharon J Peacock, Julian Parkhill, Thomas L Blundell, Sony Malhotra
Identification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India. Scientific reports 9 (1) (2019)
Sundeep Chaitanya Vedithi, Sony Malhotra, Madhusmita Das, Sheela Daniel, Nanda Kishore, Anuja George, Shantha Arumugam, Lakshmi Rajan, Mannam Ebenezer, David B Ascher, Eddy Arnold, Thomas L Blundell
Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae. Scientific reports 8 (1) (2018)
Sundeep Chaitanya Vedithi, Sony Malhotra, Madhusmita Das, Sheela Daniel, Nanda Kishore, Anuja George, Shantha Arumugam, Lakshmi Rajan, Mannam Ebenezer, David B Ascher, Eddy Arnold, Thomas L Blundell
Publisher Correction: Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae. Scientific reports 8 (1) (2018)
Jing L Wang, Camille Duboc, Qian Wu, Takashi Ochi, Shikang Liang, Susan E Tsutakawa, Susan P Lees-Miller, Marc Nadal, John A Tainer, Thomas L Blundell, Terence R Strick
Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature structural & molecular biology 25 (6) (2018)
Ryotaro Nishi, Paul W G Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Thomas L Blundell, Benedikt Mathias Kessler
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage. Scientific reports 8 (1) (2018)
Thomas L Blundell
Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry. IUCrJ 4 (Pt 4) (2017)
Anna Sigurdardottir, A Winter, A Sobkowicz, M Fragai, D Chirgadze, D B Ascher, Thomas L Blundell, E Gherardi
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chemical science 6 (11) (2015)