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Richard E Lee

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 24

Top Venues

ACS infectious diseases

Nature communications

The Journal of antibiotics

ACS medicinal chemistry letters

St. Jude Children's Research Hospital

Newcastle University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

St. Jude Children's Research Hospital Aug 15o 2009

United States

Member :: Chemical Biology and Therapeutics

Education History

Newcastle University Sep 1o 1989 - Mar 1o 1993

United Kingdom

PHD

Publications

Caroline R Buchholz, Molly S Sneddon, Joseph E McPherson, Sourav Das, Clifford T Gee, Michael J Grillo, Sergio C Chai, Richard E Lee, Taosheng Chen, Daniel A Harki, Anang A Shelat, William C K Pomerantz
Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small-Molecule Inhibitors. ACS medicinal chemistry letters 14 (10) (2023)
Keyur R Parmar, Pradeep B Lukka, Santosh Wagh, Zaid H Temrikar, Jiuyu Liu, Richard E Lee, Miriam Braunstein, Anthony J Hickey, Gregory Thomas Robertson, Mercedes Gonzalez-Juarrero, Andrea N Edginton, Bernd Meibohm
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics. Pharmaceutics 15 (6) (2023)
Chitra Subramanian, Matthew W Frank, Rajaa Sukun, Christopher E Henry, Anna Wade, Mallory E Harden, Satish Rao, Rajendra Tangallapally, Mi-Kyung Yun, Stephen W White, Richard E Lee, Uma Sinha, Charles O Rock, Suzanne Jackowski
Pantothenate kinase activation restores brain coenzyme A in a mouse model of pantothenate kinase associated neurodegeneration . The Journal of pharmacology and experimental therapeutics (2023)
Keyur R Parmar, Pradeep B Lukka, Santosh Wagh, Zaid H Temrikar, Jiuyu Liu, Richard E Lee, Miriam Braunstein, Anthony J Hickey, Gregory Thomas Robertson, Mercedes Gonzalez-Juarrero, Andrea N Edginton, Bernd Meibohm
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics. Pharmaceutics 15 (6) (2023)
Vinayak Singh, Anna E Grzegorzewicz, Stephen Fienberg, Rudolf Müller, Lutete Peguy Khonde, Olalla Sanz, Salvatore Alfonso, Beatriz Urones, Gerard Drewes, Marcus Bantscheff, Sonja Ghidelli-Disse, Thomas R Ioerger, Bhanupriya Angala, Jiuyu Liu, Richard E Lee, James C Sacchettini, Inna V Krieger, Mary Jackson, Kelly Chibale, Sandeep R Ghorpade
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis . ACS infectious diseases 8 (11) (2022)
Dmitry Leshchiner, Federico Rosconi, Bharathi Sundaresh, Emily Rudmann, Luisa Maria Nieto Ramirez, Andrew T Nishimoto, Stephen J Wood, Bimal Jana, Noemí Buján, Kaicheng Li, Jianmin Gao, Matthew Frank, Stephanie M Reeve, Richard E Lee, Charles O Rock, Jason W Rosch, Tim van Opijnen
A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance. Nature communications 13 (1) (2022)
Suresh Dharuman, Miranda J Wallace, Stephanie M Reeve, Juergen B Bulitta, Richard E Lee
Synthesis and Structure-Activity Relationship of Thioacetamide-Triazoles against Escherichia coli . Molecules (Basel, Switzerland) 27 (5) (2022)
Huarui Cui, Anand Divakaran, Zachariah J Hoell, Mikael O Ellingson, Cole R Scholtz, Huda Zahid, Jorden A Johnson, Elizabeth C Griffith, Clifford T Gee, Amani L Lee, Shalil Khanal, Ke Shi, Hideki Aihara, Vijay H Shah, Richard E Lee, Daniel A Harki, William C K Pomerantz
A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. Journal of medicinal chemistry 65 (3) (2022)
Chitra Subramanian, Matthew W Frank, Rajendra Tangallapally, Mi-Kyung Yun, Stephen W White, Richard E Lee, Charles O Rock, Suzanne Jackowski
Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia. Journal of inherited metabolic disease (2022)
Anand Divakaran, Cole R Scholtz, Huda Zahid, Wenwei Lin, Elizabeth C Griffith, Richard E Lee, Taosheng Chen, Daniel A Harki, William C K Pomerantz
Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader. ACS medicinal chemistry letters 13 (10) (2022)
Chitra Subramanian, Matthew W Frank, Rajendra Tangallapally, Mi-Kyung Yun, Anne Edwards, Stephen W White, Richard E Lee, Charles O Rock, Suzanne Jackowski
Pantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia. Science translational medicine 13 (611) (2021)
Mercedes Gonzalez-Juarrero, Pradeep B Lukka, Santosh Wagh, Amanda Walz, Jennifer Arab, Camron Pearce, Zohaib Ali, Josiah T Ryman, Keyur R Parmar, Zaid Temrikar, Juan Munoz-Gutierrez, Gregory T Robertson, Jiuyu Liu, Anne J Lenaerts, Charles Daley, Richard E Lee, Miriam Braunstein, Anthony J Hickey, Bernd Meibohm
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis. ACS infectious diseases 7 (10) (2021)
Suresh Dharuman, Laura A Wilt, Jiuyu Liu, Stephanie M Reeve, Carl W Thompson, John M Elmore, Dimitri Shcherbakov, Robin B Lee, Erik C Böttger, Richard E Lee
Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins. The Journal of antibiotics 74 (6) (2021)
Sreevalli Sharma, Ranga Rao, Stephanie M Reeve, Gregory A Phelps, Nagakumar Bharatham, Nainesh Katagihallimath, Vasanthi Ramachandran, Savitha Raveendran, Maitrayee Sarma, Anubha Nath, Teby Thomas, Dhanasekaran Manickam, Savitha Nagaraj, V Balasubramanian, Richard E Lee, Shahul Hameed P, Santanu Datta
Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria. ACS infectious diseases 7 (11) (2021)
Christian DeJarnette, Chris J Meyer, Alexander R Jenner, Arielle Butts, Tracy Peters, Martin N Cheramie, Gregory A Phelps, Nicole A Vita, Victoria C Loudon-Hossler, Richard E Lee, Glen E Palmer
Identification of Inhibitors of Fungal Fatty Acid Biosynthesis. ACS infectious diseases 7 (12) (2021)
Alex K Mugengana, Nicole A Vita, Autumn Brown Gandt, Kevin Moran, George Agyapong, Lalit K Sharma, Elizabeth C Griffith, Jiuyu Liu, Lei Yang, Ekaterina Gavrish, Kirk E Hevener, Michael D LaFleur, Richard E Lee
The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex I. ACS infectious diseases 7 (5) (2021)
Wenwei Lin, Yongtao Li, Jaeki Min, Jiuyu Liu, Lei Yang, Richard E Lee, Taosheng Chen
Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. Bioconjugate chemistry 31 (11) (2020)
Seung Wook Yang, Xin Huang, Wenwei Lin, Jaeki Min, Darcie J Miller, Anand Mayasundari, Patrick Rodrigues, Elizabeth C Griffith, Clifford T Gee, Lei Li, Weibo Xie, Richard E Lee, Zoran Rankovic, Taosheng Chen, Patrick Ryan Potts
Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases. Nature communications 11 (1) (2020)
Miranda J Wallace, Suresh Dharuman, Dinesh M Fernando, Stephanie M Reeve, Clifford T Gee, Jiangwei Yao, Elizabeth C Griffith, Gregory A Phelps, William C Wright, John M Elmore, Robin B Lee, Taosheng Chen, Richard E Lee
Discovery and Characterization of the Antimetabolite Action of Thioacetamide-Linked 1,2,3-Triazoles as Disruptors of Cysteine Biosynthesis in Gram-Negative Bacteria. ACS infectious diseases 6 (3) (2020)
Elizabeth C Griffith, Ying Zhao, Aman P Singh, Brian P Conlon, Rajendra Tangallapally, William R Shadrick, Jiuyu Liu, Miranda J Wallace, Lei Yang, John M Elmore, Yong Li, Zhong Zheng, Darcie J Miller, Martin N Cheramie, Robin B Lee, Michael D LaFleur, Kim Lewis, Richard E Lee
Ureadepsipeptides as ClpP Activators. ACS infectious diseases 5 (11) (2019)
Jennifer M Scarff, Samanthi L Waidyarachchi, Christopher J Meyer, Douglas J Lane, Weirui Chai, Margaret M Lemmon, Jiuyu Liu, Michelle M Butler, Terry L Bowlin, Richard E Lee, Rekha G Panchal
Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens. The Journal of antibiotics 72 (9) (2019)
Anna E Grzegorzewicz, Clifford Gee, Sourav Das, Jiuyu Liu, Juan Manuel Belardinelli, Victoria Jones, Michael R McNeil, Richard E Lee, Mary Jackson
Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in Mycobacterium tuberculosis. ACS infectious diseases 6 (2) (2019)
Alan J Weaver, Tami R Peters, Brian Tripet, Abigail Van Vuren, null Rakesh, Richard E Lee, Valérie Copié, Martin Teintze
Exposure of Methicillin-Resistant Staphylococcus aureus to Low Levels of the Antibacterial THAM-3ΦG Generates a Small Colony Drug-Resistant Phenotype. Scientific reports 8 (1) (2018)
Lalit Kumar Sharma, Chitra Subramanian, Mi-Kyung Yun, Matthew W Frank, Stephen W White, Charles O Rock, Richard E Lee, Suzanne Jackowski
A therapeutic approach to pantothenate kinase associated neurodegeneration. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Richard E Lee