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David Sprinzak

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 30

Top Venues

Nature communications

Development (Cambridge, England)

Science advances

eLife

California Institute of Technology

Weizmann Institute of Science (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

California Institute of Technology

United States

Postdoc :: Biology

Education History

Weizmann Institute of Science

Israel

PHD :: Physics

Publications

Roie Cohen, Shahar Taiber, Olga Loza, Shahar Kasirer, Shiran Woland, David Sprinzak
Precise alternating cellular pattern in the inner ear by coordinated hopping intercalations and delaminations. Science advances 9 (8) (2023)
Sushmita Chatterjee, Gonna Somu Naidu, Inbal Hazan-Halevy, Hanna Grobe, Assaf Ezra, Preeti Sharma, Meir Goldsmith, Srinivas Ramishetti, David Sprinzak, Ronen Zaidel-Bar, Dan Peer
Therapeutic gene silencing of CKAP5 leads to lethality in genetically unstable cancer cells. Science advances 9 (14) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Roie Cohen, Shahar Taiber, Olga Loza, Shahar Kasirer, Shiran Woland, David Sprinzak
Precise alternating cellular pattern in the inner ear by coordinated hopping intercalations and delaminations. Science advances 9 (8) (2023)
Oren Gozlan, David Sprinzak
Notch signaling in development and homeostasis. Development (Cambridge, England) 150 (4) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Oren Gozlan, David Sprinzak
Notch signaling in development and homeostasis. Development (Cambridge, England) 150 (4) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Roie Cohen, Shahar Taiber, Olga Loza, Shahar Kasirer, Shiran Woland, David Sprinzak
Precise alternating cellular pattern in the inner ear by coordinated hopping intercalations and delaminations. Science advances 9 (8) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Oren Gozlan, David Sprinzak
Notch signaling in development and homeostasis. Development (Cambridge, England) 150 (4) (2023)
Oren Gozlan, David Sprinzak
Notch signaling in development and homeostasis. Development (Cambridge, England) 150 (4) (2023)
Maibritt Kretschmer, Rose Mamistvalov, David Sprinzak, Angelika M Vollmar, Stefan Zahler
Matrix stiffness regulates Notch signaling activity in endothelial cells. Journal of cell science 136 (2) (2023)
Maibritt Kretschmer, Rose Mamistvalov, David Sprinzak, Angelika M Vollmar, Stefan Zahler
Matrix stiffness regulates Notch signaling activity in endothelial cells. Journal of cell science 136 (2) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Maibritt Kretschmer, Rose Mamistvalov, David Sprinzak, Angelika M Vollmar, Stefan Zahler
Matrix stiffness regulates Notch signaling activity in endothelial cells. Journal of cell science 136 (2) (2023)
Jacqueline Taylor, Leonie Uhl, Iris Moll, Sana Safatul Hasan, Lena Wiedmann, Jakob Morgenstern, Benedetto Daniele Giaimo, Tobias Friedrich, Elisenda Alsina-Sanchis, Francesca De Angelis Rigotti, Ronja Mülfarth, Sarah Kaltenbach, Darius Schenk, Felix Nickel, Thomas Fleming, David Sprinzak, Carolin Mogler, Thomas Korff, Adrian T Billeter, Beat P Müller-Stich, Mauricio Berriel Diaz, Tilman Borggrefe, Stephan Herzig, Maria Rohm, Juan Rodriguez-Vita, Andreas Fischer
Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia. Nature cancer (2023)
Tobias Troost, Udi Binshtok, David Sprinzak, Thomas Klein
Cis-inhibition suppresses basal Notch signaling during sensory organ precursor selection. Proceedings of the National Academy of Sciences of the United States of America 120 (23) (2023)
Oren Gozlan, David Sprinzak
Notch signaling in development and homeostasis. Development (Cambridge, England) 150 (4) (2023)
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak, Vincent C Luca
Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nature communications 14 (1) (2023)
Bassma Khamaisi, Vincent C Luca, Stephen C Blacklow, David Sprinzak
Functional Comparison between Endogenous and Synthetic Notch Systems. ACS synthetic biology 11 (10) (2022)
Yi Kuang, Anna Pyo, Natanel Eafergen, Brittany Cain, Lisa M Gutzwiller, Ofri Axelrod, Ellen K Gagliani, Matthew T Weirauch, Raphael Kopan, Rhett A Kovall, David Sprinzak, Brian Gebelein
Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor. PLoS genetics 17 (9) (2021)
Shahar Taiber, Roie Cohen, Ofer Yizhar-Barnea, David Sprinzak, Jeffrey R Holt, Karen B Avraham
Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness. EMBO molecular medicine 13 (2) (2020)
Francis M Kobia, Kristina Preusse, Quanhui Dai, Nicholas Weaver, Matthew R Hass, Praneet Chaturvedi, Sarah J Stein, Warren S Pear, Zhenyu Yuan, Rhett A Kovall, Yi Kuang, Natanel Eafergen, David Sprinzak, Brian Gebelein, Eric W Brunskill, Raphael Kopan
Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation. PLoS biology 18 (10) (2020)
Yi Kuang, Ohad Golan, Kristina Preusse, Brittany Cain, Collin J Christensen, Joseph Salomone, Ian Campbell, FearGod V Okwubido-Williams, Matthew R Hass, Zhenyu Yuan, Nathanel Eafergan, Kenneth H Moberg, Rhett A Kovall, Raphael Kopan, David Sprinzak, Brian Gebelein
Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism. eLife 9 (2020)
Cristina Porcheri, Ohad Golan, Fernando J Calero-Nieto, Roshana Thambyrajah, Cristina Ruiz-Herguido, Xiaonan Wang, Francesca Catto, Yolanda Guillén, Roshani Sinha, Jessica González, Sarah J Kinston, Samanta A Mariani, Antonio Maglitto, Chris S Vink, Elaine Dzierzak, Pierre Charbord, Berthold Göttgens, Lluís Espinosa, David Sprinzak, Anna Bigas
Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation. The EMBO journal 39 (8) (2020)
Fabian Tetzlaff, M Gordian Adam, Anja Feldner, Iris Moll, Amitai Menuchin, Juan Rodriguez-Vita, David Sprinzak, Andreas Fischer
MPDZ promotes DLL4-induced Notch signaling during angiogenesis. eLife 7 (2018)
Olga Loza, Idse Heemskerk, Nadav Gordon-Bar, Liat Amir-Zilberstein, Yunmin Jung, David Sprinzak
A synthetic planar cell polarity system reveals localized feedback on Fat4-Ds1 complexes. eLife 6 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

David Sprinzak