Gianluca Sbardella

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Venues

ChemMedChem

Journal of medicinal chemistry

Chembiochem : a European journal of chemical biology

Nature chemical biology

Università degli Studi di Salerno

Universita degli Studi di Roma La Sapienza (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Università degli Studi di Salerno May 02 2016

Italy

Professore Ordinario :: Dipartimento di Farmacia

Università degli Studi di Salerno Oct 01 2002 - May 01 2016

Italy

Associate Professor :: Dipartimento di Farmacia

Università degli Studi di Salerno Mar 01 2001 - Oct 31 2002

Italy

Assistant Professor :: Dipartimento di Farmacia

Education History

Universita degli Studi di Roma La Sapienza Nov 01 1993 - Oct 31 1996

Italy

PHD :: Studi Farmaceutici

Publications

Ciro Milite, Giuliana Sarno, Ida Pacilio, Agostino Cianciulli, Monica Viviano, Giulia Iannelli, Erica Gazzillo, Alessandra Feoli, Alessandra Cipriano, Maria Giovanna Chini, Sabrina Castellano, Giuseppe Bifulco, Gianluca Sbardella
Prodrug Approach to Exploit (S)-Alanine Amide as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors. ChemMedChem (2024)
Ciro Milite, Giuliana Sarno, Ida Pacilio, Agostino Cianciulli, Monica Viviano, Giulia Iannelli, Erica Gazzillo, Alessandra Feoli, Alessandra Cipriano, Maria Giovanna Chini, Sabrina Castellano, Giuseppe Bifulco, Gianluca Sbardella
Prodrug Approach to Exploit (S)-Alanine Amide as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors. ChemMedChem 19 (17) (2024)
Alessandra Feoli, Giuliana Sarno, Sabrina Castellano, Gianluca Sbardella
DMSO-Related Effects on Ligand-Binding Properties of Lysine Methyltransferases G9a and SETD8. Chembiochem : a European journal of chemical biology 25 (4) (2024)
Alessandra Feoli, Giuliana Sarno, Sabrina Castellano, Gianluca Sbardella
DMSO-Related Effects on Ligand-Binding Properties of Lysine Methyltransferases G9a and SETD8. Chembiochem : a European journal of chemical biology 25 (4) (2024)
Ciro Milite, Giuliana Sarno, Ida Pacilio, Agostino Cianciulli, Monica Viviano, Giulia Iannelli, Erica Gazzillo, Alessandra Feoli, Alessandra Cipriano, Maria Giovanna Chini, Sabrina Castellano, Giuseppe Bifulco, Gianluca Sbardella
Prodrug Approach to Exploit (S)-Alanine Amide as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors. ChemMedChem 19 (17) (2024)
Alessandra Feoli, Giuliana Sarno, Sabrina Castellano, Gianluca Sbardella
DMSO-Related Effects on Ligand-Binding Properties of Lysine Methyltransferases G9a and SETD8. Chembiochem : a European journal of chemical biology (2024)
Alessandra Feoli, Giuliana Sarno, Sabrina Castellano, Gianluca Sbardella
DMSO-Related Effects on Ligand-Binding Properties of Lysine Methyltransferases G9a and SETD8. Chembiochem : a European journal of chemical biology 25 (4) (2024)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Alessandra Feoli, Giulia Iannelli, Alessandra Cipriano, Ciro Milite, Lei Shen, Zhihao Wang, Andrea Hadjikyriacou, Troy L Lowe, Cyrus Safaeipour, Monica Viviano, Giuliana Sarno, Elva Morretta, Maria Chiara Monti, Yanzhong Yang, Steven G Clarke, Sandro Cosconati, Sabrina Castellano, Gianluca Sbardella
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Jean Quancard, Anna Vulpetti, Anders Bach, Brian Cox, Stéphanie M Guéret, Ingo V Hartung, Hannes F Koolman, Stefan A Laufer, Josef Messinger, Gianluca Sbardella, Russell Craft
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation. ChemMedChem (2023)
Alessandra Cipriano, Monica Viviano, Alessandra Feoli, Ciro Milite, Giuliana Sarno, Sabrina Castellano, Gianluca Sbardella
NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors. Journal of medicinal chemistry (2023)
Samantha D Creighton, Kristen H Jardine, Alexa Desimone, Megan Zmetana, Sabrina Castellano, Ciro Milite, Gianluca Sbardella, Boyer D Winters
Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice. Learning & memory (Cold Spring Harbor, N.Y.) 29 (3) (2022)
Giulia Iannelli, Ciro Milite, Nils Marechal, Vincent Cura, Luc Bonnefond, Nathalie Troffer-Charlier, Alessandra Feoli, Donatella Rescigno, Yalong Wang, Alessandra Cipriano, Monica Viviano, Mark T Bedford, Jean Cavarelli, Sabrina Castellano, Gianluca Sbardella
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach. Journal of medicinal chemistry 65 (17) (2022)
Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella
Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain. ChemMedChem 17 (20) (2022)
Alessandra Feoli, Monica Viviano, Alessandra Cipriano, Ciro Milite, Sabrina Castellano, Gianluca Sbardella
Lysine methyltransferase inhibitors: where we are now. RSC chemical biology 3 (4) (2021)
Jean Quancard, Anders Bach, Brian Cox, Russell Craft, Dirk Finsinger, Stéphanie M Guéret, Ingo V Hartung, Stefan A Laufer, Josef Messinger, Gianluca Sbardella, Hannes F Koolman
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery. ChemMedChem 16 (11) (2021)
Lucia Scisciola, Federica Sarno, Vincenzo Carafa, Sandro Cosconati, Salvatore Di Maro, Loreta Ciuffreda, Antonella De Angelis, Paola Stiuso, Alessandra Feoli, Gianluca Sbardella, Lucia Altucci, Angela Nebbioso
Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence. Epigenetics 15 (6-7) (2020)
Alessandra Feoli, Vincenzo Pisapia, Monica Viviano, Sabrina Castellano, Tanja Bartoschik, Gianluca Sbardella
Development of a Microscale Thermophoresis-Based Method for Screening and Characterizing Inhibitors of the Methyl-Lysine Reader Protein MRG15. SLAS discovery : advancing life sciences R & D 26 (1) (2020)
Jean Quancard, Brian Cox, Dirk Finsinger, Stéphanie M Guéret, Ingo V Hartung, Hannes F Koolman, Josef Messinger, Gianluca Sbardella, Stefan A Laufer
The European Federation for Medicinal Chemistry (EFMC) Best Practice Initiative: Validating Chemical Probes. ChemMedChem 15 (24) (2020)
Roberto Bassi, Enrico M Bucci, Raffaele A Calogero, Piero Carnici, Gennaro Ciliberto, Pellegrino Conte, Michele De Luca, Gilberto Corbellini, Antonio Giordano, Luigi Marchionni, Giacomina Massaro Giordano, Angelo Parini, Gianluca Sbardella
Look for methods, not conclusions. Cell death & disease 10 (12) (2019)
Ciro Milite, Alessandra Feoli, John R Horton, Donatella Rescigno, Alessandra Cipriano, Vincenzo Pisapia, Monica Viviano, Giacomo Pepe, Giorgio Amendola, Ettore Novellino, Sandro Cosconati, Xiaodong Cheng, Sabrina Castellano, Gianluca Sbardella
Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure. Journal of medicinal chemistry 62 (5) (2019)
Narkhyun Bae, Monica Viviano, Xiaonan Su, Jie Lv, Donghang Cheng, Cari Sagum, Sabrina Castellano, Xue Bai, Claire Johnson, Mahmoud Ibrahim Khalil, Jianjun Shen, Kaifu Chen, Haitao Li, Gianluca Sbardella, Mark T Bedford
Developing Spindlin1 small-molecule inhibitors by using protein microarrays. Nature chemical biology 13 (7) (2017)
Pietro Campiglia, Gianluca Sbardella
The 23(rd) National Meeting of the Medicinal Chemistry Division of the Italian Chemical Society (DCF-SCI) in Salerno (NMMC 2015). ChemMedChem 11 (16) (2017)
Ciro Milite, Elisabetta Barresi, Eleonora Da Pozzo, Barbara Costa, Monica Viviano, Amalia Porta, Anna Messere, Gianluca Sbardella, Federico Da Settimo, Ettore Novellino, Sandro Cosconati, Sabrina Castellano, Sabrina Taliani, Claudia Martini
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO). Journal of medicinal chemistry 60 (18) (2017)
Matthijs J van Haren, Nils Marechal, Nathalie Troffer-Charlier, Agostino Cianciulli, Gianluca Sbardella, Jean Cavarelli, Nathaniel I Martin
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1. Proceedings of the National Academy of Sciences of the United States of America 114 (14) (2017)
Maria Chiara Proto, Donatella Fiore, Chiara Piscopo, Silvia Franceschelli, Valentina Bizzarro, Chiara Laezza, Gianluigi Lauro, Alessandra Feoli, Alessandra Tosco, Giuseppe Bifulco, Gianluca Sbardella, Maurizio Bifulco, Patrizia Gazzerro
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer. Scientific reports 7 (1) (2017)
Narkhyun Bae, Min Gao, Xu Li, Tolkappiyan Premkumar, Gianluca Sbardella, Junjie Chen, Mark T Bedford
A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1. The Journal of biological chemistry 292 (51) (2017)
Ciro Milite, Alessandra Feoli, Monica Viviano, Donatella Rescigno, Agostino Cianciulli, Amodio Luca Balzano, Antonello Mai, Sabrina Castellano, Gianluca Sbardella
The emerging role of lysine methyltransferase SETD8 in human diseases. Clinical epigenetics 8 (2016)
Ciro Milite, Alessandra Feoli, Monica Viviano, Donatella Rescigno, Antonello Mai, Sabrina Castellano, Gianluca Sbardella
Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors. ChemMedChem 11 (16) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Gianluca Sbardella