Anu Suomalainen

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Topics

Parkinson Disease

Mitochondrial Dna

Top Venues

Nature communications

Communications biology

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature (2024)
Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature 628 (8009) (2024)
Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature 628 (8009) (2024)
Catalina Vasilescu, Mert Colpan, Tiina H Ojala, Tuula Manninen, Aino Mutka, Kaisa Ylänen, Otto Rahkonen, Tuija Poutanen, Laura Martelius, Reena Kumari, Helena Hinterding, Virginia Brilhante, Simo Ojanen, Pekka Lappalainen, Juha Koskenvuo, Christopher J Carroll, Velia M Fowler, Carol C Gregorio, Anu Suomalainen
Recessive TMOD1 mutation causes childhood cardiomyopathy. Communications biology 7 (1) (2024)
Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature 628 (8009) (2024)
Catalina Vasilescu, Mert Colpan, Tiina H Ojala, Tuula Manninen, Aino Mutka, Kaisa Ylänen, Otto Rahkonen, Tuija Poutanen, Laura Martelius, Reena Kumari, Helena Hinterding, Virginia Brilhante, Simo Ojanen, Pekka Lappalainen, Juha Koskenvuo, Christopher J Carroll, Velia M Fowler, Carol C Gregorio, Anu Suomalainen
Recessive TMOD1 mutation causes childhood cardiomyopathy. Communications biology 7 (1) (2024)
Catalina Vasilescu, Mert Colpan, Tiina H Ojala, Tuula Manninen, Aino Mutka, Kaisa Ylänen, Otto Rahkonen, Tuija Poutanen, Laura Martelius, Reena Kumari, Helena Hinterding, Virginia Brilhante, Simo Ojanen, Pekka Lappalainen, Juha Koskenvuo, Christopher J Carroll, Velia M Fowler, Carol C Gregorio, Anu Suomalainen
Recessive TMOD1 mutation causes childhood cardiomyopathy. Communications biology 7 (1) (2024)
Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature (2024)
Catalina Vasilescu, Mert Colpan, Tiina H Ojala, Tuula Manninen, Aino Mutka, Kaisa Ylänen, Otto Rahkonen, Tuija Poutanen, Laura Martelius, Reena Kumari, Helena Hinterding, Virginia Brilhante, Simo Ojanen, Pekka Lappalainen, Juha Koskenvuo, Christopher J Carroll, Velia M Fowler, Carol C Gregorio, Anu Suomalainen
Recessive TMOD1 mutation causes childhood cardiomyopathy. Communications biology 7 (1) (2024)
Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature (2024)
Catalina Vasilescu, Mert Colpan, Tiina H Ojala, Tuula Manninen, Aino Mutka, Kaisa Ylänen, Otto Rahkonen, Tuija Poutanen, Laura Martelius, Reena Kumari, Helena Hinterding, Virginia Brilhante, Simo Ojanen, Pekka Lappalainen, Juha Koskenvuo, Christopher J Carroll, Velia M Fowler, Carol C Gregorio, Anu Suomalainen
Recessive TMOD1 mutation causes childhood cardiomyopathy. Communications biology 7 (1) (2024)
Juan Cruz Landoni, Semin Erkul, Tuomas Laalo, Steffi Goffart, Riikka Kivelä, Karlo Skube, Anni I Nieminen, Sara A Wickström, James Bruce Stewart, Anu Suomalainen
Overactive mitochondrial DNA replication disrupts perinatal cardiac maturation. Nature communications 15 (1) (2024)
Yilin Kang, Jussi M Hepojoki, Rocio Sartori Maldonado, Takayuki Mito, Mügen Terzioglu, Tuula Manninen, Ravi Kant, Sachin Singh, Alaa Othman, Rohit Verma, Johanna Uusimaa, Kirmo Wartiovaara, Lauri Kareinen, Nicola Zamboni, Tuula Anneli Nyman, Anders Paetau, Anja Kipar, Olli Vapalahti, Anu Suomalainen
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. Nature 628 (8009) (2024)
Lilli Ikonen, Sini Pirnes-Karhu, Swagat Pradhan, Howard Trevor Jacobs, Marten Szibor, Anu Suomalainen
Alternative oxidase causes cell type- and tissue-specific responses in mutator mice. Life science alliance 6 (11) (2023)
Rajarshi Chakrabarti, Tak Shun Fung, Taewook Kang, Pieti W Elonkirjo, Anu Suomalainen, Edward J Usherwood, Henry N Higgs
Mitochondrial dysfunction triggers actin polymerization necessary for rapid glycolytic activation. The Journal of cell biology 221 (11) (2022)
Olesia Ignatenko, Satu Malinen, Sofiia Rybas, Helena Vihinen, Joni Nikkanen, Aleksander Kononov, Eija S Jokitalo, Gulayse Ince-Dunn, Anu Suomalainen
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes. The Journal of cell biology 222 (1) (2022)
Marjo K Hytönen, Riika Sarviaho, Christopher B Jackson, Pernilla Syrjä, Tarja S Jokinen, Kaspar Matiasek, Marco Rosati, Cristina Dallabona, Enrico Baruffini, Ileana Quintero, Meharji Arumilli, Geoffray Monteuuis, Jonas Donner, Marjukka Anttila, Anu Suomalainen, Laurence Albert Bindoff, Hannes T Lohi
In-frame deletion in canine PITRM1 is associated with a severe early-onset epilepsy, mitochondrial dysfunction and neurodegeneration. Human genetics 140 (11) (2021)
Anna Kuukasjärvi, Juan C Landoni, Jyrki Kaukonen, Mika Juhakoski, Mari Auranen, Tommi Torkkeli, Vidya Velagapudi, Anu Suomalainen
IMPDH2: a new gene associated with dominant juvenile-onset dystonia-tremor disorder. European journal of human genetics : EJHG 29 (12) (2021)
Topi Hovinen, Liisa Korkalo, Riitta I Freese, Essi Skaffari, Pirjo Isohanni, Mikko Niemi, Jaakko Nevalainen, Helena Gylling, Nicola Zamboni, Maijaliisa Erkkola, Anu Suomalainen
Vegan diet in young children remodels metabolism and challenges the statuses of essential nutrients. EMBO molecular medicine 13 (2) (2021)
Philipp Gut, Sanna Matilainen, Jesse G Meyer, Pieti Pällijeff, Joy Richard, Christopher J Carroll, Liliya Euro, Christopher B Jackson, Pirjo Isohanni, Berge A Minassian, Reem A Alkhater, Elsebet Østergaard, Gabriele Civiletto, Alice Parisi, Jonathan Thevenet, Matthew J Rardin, Wenjuan He, Yuya Nishida, John C Newman, Xiaojing Liu, Stefan Christen, Sofia Moco, Jason W Locasale, Birgit Schilling, Anu Suomalainen, Eric Verdin
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. Nature communications 11 (1) (2020)
Erika Ignatius, Pirjo Isohanni, Max Pohjanpelto, Päivi Lahermo, Simo Ojanen, Virginia Brilhante, Eino Palin, Anu Suomalainen, Tuula R I Lönnqvist, Christopher J Carroll
Genetic background of ataxia in children younger than 5 years in Finland. Neurology. Genetics 6 (4) (2020)
Olesia Ignatenko, Joni Nikkanen, Alexander Kononov, Nicola Zamboni, Gulayse Ince-Dunn, Anu Suomalainen
Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect. Life science alliance 3 (9) (2020)
Riikka H Hämäläinen, Juan Cruz Landoni, Kati J Ahlqvist, Steffi Goffart, Sanna Ryytty, M Obaidur Rahman, Virginia Brilhante, Katherine Icay, Sampsa Hautaniemi, Liya Wang, Marikki Laiho, Anu Suomalainen
Reply to: Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos. Nature metabolism 2 (8) (2020)
Jason W Miklas, Elisa C Clark, Shiri Levy, Damien Detraux, Andrea Leonard, Kevin Beussman, Megan R Showalter, Alec T Smith, Peter Hofsteen, Xiulan Yang, Jesse Macadangdang, Tuula Manninen, Daniel Raftery, Anup Madan, Anu Suomalainen, Deok-Ho Kim, Charles E Murry, Oliver Fiehn, Nathan J Sniadecki, Yuliang Wang, Hannele Ruohola-Baker
Author Correction: TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. Nature communications 11 (1) (2020)
Jason W Miklas, Elisa C Clark, Shiri Levy, Damien Detraux, Andrea Leonard, Kevin Beussman, Megan R Showalter, Alec T Smith, Peter Hofsteen, Xiulan Yang, Jesse Macadangdang, Tuula Manninen, Daniel Raftery, Anup Madan, Anu Suomalainen, Deok-Ho Kim, Charles E Murry, Oliver Fiehn, Nathan J Sniadecki, Yuliang Wang, Hannele Ruohola-Baker
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. Nature communications 10 (1) (2019)
Jana Buzkova, Joni Nikkanen, Sofia Ahola, Anna H Hakonen, Ksenia Sevastianova, Topi Hovinen, Hannele Yki-Järvinen, Kirsi H Pietiläinen, Tuula Lönnqvist, Vidya Velagapudi, Christopher J Carroll, Anu Suomalainen
Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers. EMBO molecular medicine 10 (12) (2019)
Joni Nikkanen, Juan Cruz Landoni, Diego Balboa, Maarja Haugas, Juha Partanen, Anders Paetau, Pirjo Isohanni, Virginia Brilhante, Anu Suomalainen
A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions. EMBO molecular medicine 10 (1) (2019)
Riikka H Hämäläinen, Juan Cruz Landoni, Kati J Ahlqvist, Steffi Goffart, Sanna Ryytty, M Obaidur Rahman, Virginia Brilhante, Katherine Icay, Sampsa Hautaniemi, Liya Wang, Marikki Laiho, Anu Suomalainen
Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias. Nature metabolism 1 (10) (2019)
Olesia Ignatenko, Dmitri Chilov, Ilse Paetau, Elena de Miguel, Christopher B Jackson, Gabrielle Capin, Anders Paetau, Mugen Terzioglu, Liliya Euro, Anu Suomalainen
Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy. Nature communications 9 (1) (2018)
Juan Cruz Landoni, Liya Wang, Anu Suomalainen
Quantitative solid-phase assay to measure deoxynucleoside triphosphate pools. Biology methods & protocols 3 (1) (2018)
Uwe Richter, Molly E Evans, Wesley C Clark, Paula Marttinen, Eric A Shoubridge, Anu Suomalainen, Anna Wredenberg, Anna Wedell, Tao Pan, Brendan J Battersby
RNA modification landscape of the human mitochondrial tRNALys regulates protein synthesis. Nature communications 9 (1) (2018)
Sofia Ahola, Mari Auranen, Pirjo Isohanni, Satu Niemisalo, Niina Urho, Jana Buzkova, Vidya Velagapudi, Nina Lundbom, Antti Hakkarainen, Tiina Muurinen, Päivi Piirilä, Kirsi H Pietiläinen, Anu Suomalainen
Modified Atkins diet induces subacute selective ragged-red-fiber lysis in mitochondrial myopathy patients. EMBO molecular medicine 8 (11) (2016)