Ashley M Buckle

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 28

Top Venues

International journal of molecular sciences

Scientific reports

Journal of immunology (Baltimore, Md. : 1950)

Nature chemical biology

PTNG Consulting

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

PTNG Consulting Jan 01 2020

Australia

CEO/Founder

Monash University

Australia

Group Leader/PI :: Biochemistry and Molecular Biology

MRC Laboratory of Molecular Biology

United Kingdom

Postdoc/MRC Staff scientist :: Centre for Protein Engineering

Education History

University of Cambridge

United Kingdom

PHD :: Chemistry

Publications

Edward D Chan, Paul T King, Xiyuan Bai, Allen M Schoffstall, Robert A Sandhaus, Ashley M Buckle
The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions. International journal of molecular sciences 25 (3) (2024)
Edward D Chan, Paul T King, Xiyuan Bai, Allen M Schoffstall, Robert A Sandhaus, Ashley M Buckle
The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions. International journal of molecular sciences 25 (3) (2024)
Edward D Chan, Paul T King, Xiyuan Bai, Allen M Schoffstall, Robert A Sandhaus, Ashley M Buckle
The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions. International journal of molecular sciences 25 (3) (2024)
Edward D Chan, Paul T King, Xiyuan Bai, Allen M Schoffstall, Robert A Sandhaus, Ashley M Buckle
The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions. International journal of molecular sciences 25 (3) (2024)
Edward D Chan, Paul T King, Xiyuan Bai, Allen M Schoffstall, Robert A Sandhaus, Ashley M Buckle
The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions. International journal of molecular sciences 25 (3) (2024)
Xiyuan Bai, An Bai, Michele Tomasicchio, James R Hagman, Ashley M Buckle, Arnav Gupta, Vineela Kadiyala, Shaun Bevers, Karina A Serban, Kevin Kim, Zhihong Feng, Kathrin Spendier, Guy Hagen, Lorelenn Fornis, David E Griffith, Monika Dzieciatkowska M, Robert A Sandhaus, Anthony N Gerber, Edward D Chan
α1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages. Journal of immunology (Baltimore, Md. : 1950) 209 (9) (2022)
Xiyuan Bai, Ashley M Buckle, Eszter K Vladar, Edward N Janoff, Reeti Khare, Diane Ordway, David Beckham, Lorelenn B Fornis, Abraham Majluf-Cruz, Randolph V Fugit, Brian M Freed, Soohyun Kim, Robert A Sandhaus, Edward D Chan
Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Scientific reports 12 (1) (2022)
Xiyuan Bai, Ashley M Buckle, Eszter K Vladar, Edward N Janoff, Reeti Khare, Diane Ordway, David Beckham, Lorelenn B Fornis, Abraham Majluf-Cruz, Randolph V Fugit, Brian M Freed, Soohyun Kim, Robert A Sandhaus, Edward D Chan
Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Scientific reports 12 (1) (2022)
Meri Ayurini, Peter G Chandler, Paul D O'Leary, Ruoxin Wang, David Rudd, Karen D Milewska, Lara R Malins, Ashley M Buckle, Joel F Hooper
Polymer End Group Control through a Decarboxylative Cobalt-Mediated Radical Polymerization: New Avenues for Synthesizing Peptide, Protein, and Nanomaterial Conjugates. JACS Au 2 (1) (2021)
Sebastian S Broendum, Daniel E Williams, Brooke K Hayes, Felix Kraus, James Fodor, Ben E Clifton, Anne Geert Volbeda, Jeroen D C Codee, Blake T Riley, Nyssa Drinkwater, Kylie A Farrow, Kirill Tsyganov, Ryan D Heselpoth, Daniel C Nelson, Colin J Jackson, Ashley M Buckle, Sheena McGowan
High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus. Molecular microbiology 116 (2) (2021)
Matthew A Spence, Matthew D Mortimer, Ashley M Buckle, Bui Quang Minh, Colin J Jackson
A Comprehensive Phylogenetic Analysis of the Serpin Superfamily. Molecular biology and evolution 38 (7) (2021)
Christopher Szeto, Joseph I Bloom, Hannah Sloane, Christian A Lobos, James Fodor, Dhilshan Jayasinghe, Demetra S M Chatzileontiadou, Emma J Grant, Ashley M Buckle, Stephanie Gras
Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition. International journal of molecular sciences 21 (19) (2020)
James Fodor, Michael Brand, Rebecca J Stones, Ashley M Buckle
Intrinsic limitations in mainstream methods of identifying network motifs in biology. BMC bioinformatics 21 (1) (2020)
Peter G Chandler, Ashley M Buckle
Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain. Cells 9 (3) (2020)
James Fodor, Blake T Riley, Itamar Kass, Ashley M Buckle, Natalie A Borg
The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome. Scientific reports 9 (1) (2019)
Blake T Riley, Olga Ilyichova, Simon J de Veer, Joakim E Swedberg, Emily Wilson, David E Hoke, Jonathan M Harris, Ashley M Buckle
KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors. Biochemistry 58 (21) (2019)
Emilia M Marijanovic, James Fodor, Blake T Riley, Benjamin Thomas Porebski, Mauricio G S Costa, Itamar Kass, David E Hoke, Sheena McGowan, Ashley M Buckle
Reactive centre loop dynamics and serpin specificity. Scientific reports 9 (1) (2019)
Nathan W Zammit, Owen M Siggs, Paul E Gray, Keisuke Horikawa, David B Langley, Stacey N Walters, Stephen R Daley, Claudia Loetsch, Joanna Warren, Jin Yan Yap, Daniele Cultrone, Amanda J Russell, Elisabeth K Malle, Jeanette E Villanueva, Mark J Cowley, Velimir Gayevskiy, Marcel E Dinger, Robert Brink, David Zahra, Geeta Chaudhri, Gunasegaran Karupiah, Belinda Whittle, Carla Roots, Edward Bertram, Michiko Yamada, Yogesh Jeelall, Anselm Enders, Benjamin E Clifton, Peter D Mabbitt, Colin J Jackson, Susan R Watson, Craig N Jenne, Lewis L Lanier, Tim Wiltshire, Matthew H Spitzer, Garry P Nolan, Frank Schmitz, Alan Aderem, Benjamin Thomas Porebski, Ashley M Buckle, Derek W Abbott, John B Ziegler, Maria E Craig, Paul Benitez-Aguirre, Juliana Teo, Stuart G Tangye, Cecile King, Melanie Wong, Murray P Cox, Wilson Phung, Jia Tang, Wendy Sandoval, Ingrid E Wertz, Daniel Christ, Christopher C Goodnow, Shane T Grey
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity. Nature immunology 20 (10) (2019)
Jiaul Islam, Blake T Riley, Christian Fercher, Martina L Jones, Ashley M Buckle, Christopher B Howard, Rosalind P Cox, Toby D M Bell, Stephen Mahler, Simon R Corrie
Wavelength-Dependent Fluorescent Immunosensors via Incorporation of Polarity Indicators near the Binding Interface of Antibody Fragments. Analytical chemistry 91 (12) (2019)
Charlotte Gimpel, Damian Gawel, Ashley M Buckle, J Paul Banga
Thyroid Peroxidase Revisited - What's New? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 51 (12) (2019)
Blake T Riley, David E Hoke, Sheena McGowan, Ashley M Buckle
Crystal structure of the inhibitor-free form of the serine protease kallikrein-4. Acta crystallographica. Section F, Structural biology communications 75 (Pt 8) (2019)
James Fodor, Blake T Riley, Natalie A Borg, Ashley M Buckle
Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed. Journal of immunology (Baltimore, Md. : 1950) 200 (12) (2018)
Sarah C Atkinson, Michelle D Audsley, Kim G Lieu, Glenn A Marsh, David R Thomas, Steven M Heaton, Jason J Paxman, Kylie M Wagstaff, Ashley M Buckle, Gregory W Moseley, David A Jans, Natalie A Borg
Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V. Scientific reports 8 (1) (2018)
Wei Yang, Blake T Riley, Xiangyun Lei, Benjamin T Porebski, Itamar Kass, Ashley M Buckle, Sheena McGowan
Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1. ChemMedChem 13 (23) (2018)
Romain Rouet, David B Langley, Peter Schofield, Mary Christie, Brendan Roome, Benjamin T Porebski, Ashley M Buckle, Ben E Clifton, Colin J Jackson, Daniela Stock, Daniel Christ
Structural reconstruction of protein ancestry. Proceedings of the National Academy of Sciences of the United States of America 114 (15) (2017)
Maria-Cristina Keightley, Duncan P Carradice, Judith E Layton, Luke Pase, Julien Y Bertrand, Johannes G Wittig, Aleksandar Dakic, Andrew P Badrock, Nicholas J Cole, David Traver, Stephen L Nutt, Julia McCoey, Ashley M Buckle, Joan K Heath, Graham J Lieschke
The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nature communications 8 (2017)
Wei Yang, Blake T Riley, Xiangyun Lei, Benjamin T Porebski, Itamar Kass, Ashley M Buckle, Sheena McGowan
Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases. Journal of biomolecular structure & dynamics 36 (10) (2017)
Eleanor Campbell, Miriam Kaltenbach, Galen J Correy, Paul D Carr, Benjamin T Porebski, Emma K Livingstone, Livnat Afriat-Jurnou, Ashley M Buckle, Martin Weik, Florian Hollfelder, Nobuhiko Tokuriki, Colin J Jackson
The role of protein dynamics in the evolution of new enzyme function. Nature chemical biology 12 (11) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ashley M Buckle