Ashraf H Abadi

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Topics

Multidrug Resistant

Hepatitis C Virus

Anti Inflammatory

Top Venues

Archiv der Pharmazie

Molecules (Basel, Switzerland)

Pharmaceuticals (Basel, Switzerland)

Future medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, Shun-Hua Chen, Hsin-Chieh Lin, Dalia S El-Gamil, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity. Future medicinal chemistry 16 (12) (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie (2024)
Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, Shun-Hua Chen, Hsin-Chieh Lin, Dalia S El-Gamil, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity. Future medicinal chemistry 16 (12) (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie 357 (4) (2024)
Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, Shun-Hua Chen, Hsin-Chieh Lin, Dalia S El-Gamil, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity. Future medicinal chemistry 16 (12) (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie 357 (4) (2024)
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, Yu-Chieh Su, Ming-Hua Shiao, Gary A Piazza, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N -Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents. Cancers 16 (11) (2024)
Habiba G Aboelfotouh, Mennatallah Abdallah, Hend Khalifa, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N 1 -Benzoylated 5-(4-pyridinyl)indazole-based kinase inhibitors: Attaining haspin and Clk4 selectivity via modulation of the benzoyl substituents. Archiv der Pharmazie 357 (6) (2024)
Habiba G Aboelfotouh, Mennatallah Abdallah, Hend Khalifa, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N 1 -Benzoylated 5-(4-pyridinyl)indazole-based kinase inhibitors: Attaining haspin and Clk4 selectivity via modulation of the benzoyl substituents. Archiv der Pharmazie (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie 357 (4) (2024)
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, Yu-Chieh Su, Ming-Hua Shiao, Gary A Piazza, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N -Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents. Cancers 16 (11) (2024)
Nermin S Ahmed, Heba E El-Nakib, Marian M Ramsis, Nouran O Albably, Jannette Wober, Jan J Weigand, Kai Schwedtmann, Oliver Zierau, Ashraf H Abadi
Structure-Activity Relationships of Triphenylethylene Derivatives and Their Evaluation as Anticancer and Antiviral Agents. ACS omega 8 (29) (2023)
Lina Ammar, Hung-Yu Lin, Shou-Ping Shih, Tsen-Ni Tsai, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Ashraf H Abadi
Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer. Molecules (Basel, Switzerland) 28 (2) (2023)
Lina Ammar, Hung-Yu Lin, Shou-Ping Shih, Tsen-Ni Tsai, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Ashraf H Abadi
Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer. Molecules (Basel, Switzerland) 28 (2) (2023)
Lina Ammar, Hung-Yu Lin, Shou-Ping Shih, Tsen-Ni Tsai, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Ashraf H Abadi
Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer. Molecules (Basel, Switzerland) 28 (2) (2023)
Mirja Harms, Rikke Fabech Hansson, Andrea Gilg, Yasser Almeida-Hernández, Jessica Löffler, Armando Alexei Rodríguez, Monica M W Habib, Dan Albers, Nermin S Ahmed, Ashraf H Abadi, Gordon Winter, Volker Rasche, Ambros J Beer, Gilbert Weidinger, Nico Preising, Ludger Ständker, Sebastian Wiese, Elsa Sanchez-Garcia, Alexander N Zelikin, Jan Münch
Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability. Journal of medicinal chemistry (2023)
Lina Ammar, Hung-Yu Lin, Shou-Ping Shih, Tsen-Ni Tsai, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Ashraf H Abadi
Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer. Molecules (Basel, Switzerland) 28 (2) (2023)
Ahmed K ElHady, Dalia S El-Gamil, Mohammad Abdel-Halim, Ashraf H Abadi
Advancements in Phosphodiesterase 5 Inhibitors: Unveiling Present and Future Perspectives. Pharmaceuticals (Basel, Switzerland) 16 (9) (2023)
Lina Ammar, Hung-Yu Lin, Shou-Ping Shih, Tsen-Ni Tsai, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Ashraf H Abadi
Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer. Molecules (Basel, Switzerland) 28 (2) (2023)
Sarah S Darwish, Po-Jen Chen, Mostafa M Hamed, Reem A Wagdy, Shun-Hua Chen, Ashraf H Abadi, Mohammad Abdel-Halim, Tsong-Long Hwang, Matthias Engel
Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Jehad Hamdy, Nouran Emadeldin, Mostafa M Hamed, Efseveia Frakolaki, Sotirios Katsamakas, Niki Vassilaki, Grigoris Zoidis, Anna Katharina Herta Hirsch, Mohammad Abdel-Halim, Ashraf H Abadi
Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (5) (2022)
Ahmed K ElHady, Dalia S El-Gamil, Ashraf H Abadi, Mohammad Abdel-Halim, Matthias Engel
An overview of cdc2-like kinase 1 (Clk1) inhibitors and their therapeutic indications. Medicinal research reviews (2022)
Mai H A Mousa, Nermin S Ahmed, Kai Schwedtmann, Efseveia Frakolaki, Niki Vassilaki, Grigoris Zoidis, Jan J Weigand, Ashraf H Abadi
Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors. Pharmaceuticals (Basel, Switzerland) 14 (4) (2021)
Mohammad Abdel-Halim, Sara Sigler, Nora A S Racheed, Amr Hefnawy, Reem K Fathalla, Mennatallah A Hammam, Ahmed Maher, Yulia Maxuitenko, Adam B Keeton, Rolf Wolfgang Hartmann, Matthias Engel, Gary A Piazza, Ashraf H Abadi
From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity. Journal of medicinal chemistry 64 (8) (2021)
Heba E Elnakib, Marian M Ramsis, Nouran O Albably, Merna A Vector, Jan J Weigand, Kai Schwedtmann, Jannette Wober, Oliver Zierau, Günter Vollmer, Ashraf H Abadi, Nermin S Ahmed
Manipulating Estrogenic/Anti-Estrogenic Activity of Triphenylethylenes towards Development of Novel Anti-Neoplastic SERMs. International journal of molecular sciences 22 (22) (2021)
Youssef Aboushady, Moustafa Gabr, Ahmed K ElHady, Mohamed Salah, Ashraf H Abadi, Gerrit Wilms, Walter Becker, Mohammad Abdel-Halim, Matthias Engel
Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases. ACS chemical neuroscience 12 (22) (2021)
Lina Y El-Sharkawy, Rowaida A El-Sakhawy, Mohammad Abdel-Halim, Kevin Lee, Gary A Piazza, Christian Ducho, Rolf W Hartmann, Ashraf H Abadi
Design and synthesis of novel annulated thienopyrimidines as phosphodiesterase 5 (PDE5) inhibitors. Archiv der Pharmazie 351 (5) (2018)
Triveena M Ramsis, Shereen E Abdel Karim, Niki Vassilaki, Efseveia Frakolaki, Ahmed A M Kamal, Grigoris Zoidis, Nermin S Ahmed, Ashraf H Abadi
Expanding the chemical space of anti-HCV NS5A inhibitors by stereochemical exchange and peptidomimetic approaches. Archiv der Pharmazie 351 (7) (2018)