Anna Katharina Herta Hirsch (A K H Hirsch, Anna K H Hirsch)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 107

Top Venues

Journal of medicinal chemistry

Nature communications

ACS infectious diseases

ChemMedChem

Helmholtz Institute for Pharmaceutical Research Saarland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Helmholtz Institute for Pharmaceutical Research Saarland May 01 2017

Germany

Full professor and Head of department :: Drug Design and Optimization

Publications

Ioulia Antonia Exapicheidou, Atanaz Shams, Hamza Ibrahim, Aleksei Tsarenko, Michael Backenköhler, Mostafa M Hamed, Eleonora Diamanti, Andrea Volkamer, Dirk J Slotboom, Anna Katharina Herta Hirsch
Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT. Chemical communications (Cambridge, England) (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases 10 (3) (2024)
Eleonora Diamanti, Paulo Cesar Telles de Souza, Inda Setyawati, Spyridon Bousis, Leticia Monjas, Lotteke J Y M Swier, Atanaz Shams, Aleksei Tsarenko, Weronika K Stanek, Manuel Jäger, Siewert-Jan Marrink, Dirk Jan Slotboom, Anna Katharina Herta Hirsch
Author Correction: Identification of inhibitors targeting the energy-coupling factor (ECF) transporters. Communications biology 7 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Jörg Haupenthal, Muhammad Rafehi, Andreas Martin Kany, Anne Lespine, Katja Stefan, Anna Katharina Herta Hirsch, Sven Marcel Stefan
Target repurposing unravels avermectins and derivatives as novel antibiotics inhibiting energy-coupling factor transporters (ECFTs). Archiv der Pharmazie 357 (9) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Olga Metelkina, Jelena Konstantinović, Andreas Klein, Roya Shafiei, Mario Fares, Alaa Alhayek, Samir Yahiaoui, Walid A M Elgaher, Jörg Haupenthal, Alexander Titz, Anna Katharina Herta Hirsch
Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB. Chemical science 15 (33) (2024)
Victor O Gawriljuk, Andre Schutzer Godoy, Rick Oerlemans, Luise A T Welker, Anna Katharina Herta Hirsch, Matthew R Groves
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain. Nature communications 15 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Walter Hofer, Felix Deschner, Gwenaëlle Jézéquel, Laìs Pessanha de Carvalho, Noran Abdel-Wadood, Linda Pätzold, Steffen Bernecker, Bernd Morgenstern, Andreas Martin Kany, Miriam Große, Marc Stadler, Markus Bischoff, Anna Katharina Herta Hirsch, Jana Held, Jennifer Herrmann, Daniel Krug
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application. Angewandte Chemie (International ed. in English) 63 (19) (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases 10 (3) (2024)
Jörg Haupenthal, Muhammad Rafehi, Andreas Martin Kany, Anne Lespine, Katja Stefan, Anna Katharina Herta Hirsch, Sven Marcel Stefan
Target repurposing unravels avermectins and derivatives as novel antibiotics inhibiting energy-coupling factor transporters (ECFTs). Archiv der Pharmazie (2024)
Maria Braun-Cornejo, Camilla Ornago, Vidhisha Sonawane, Jörg Haupenthal, Andreas Martin Kany, Eleonora Diamanti, Gwenaëlle Jézéquel, Norbert Reiling, Wulf Blankenfeldt, Peter Maas, Anna Katharina Herta Hirsch
Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium tuberculosis IspE. ACS omega 9 (36) (2024)
Eleonora Diamanti, Paulo Cesar Telles de Souza, Inda Setyawati, Spyridon Bousis, Leticia Monjas, Lotteke J Y M Swier, Atanaz Shams, Aleksei Tsarenko, Weronika K Stanek, Manuel Jäger, Siewert-Jan Marrink, Dirk Jan Slotboom, Anna Katharina Herta Hirsch
Author Correction: Identification of inhibitors targeting the energy-coupling factor (ECF) transporters. Communications biology 7 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Ioulia Antonia Exapicheidou, Atanaz Shams, Hamza Ibrahim, Aleksei Tsarenko, Michael Backenköhler, Mostafa M Hamed, Eleonora Diamanti, Andrea Volkamer, Dirk J Slotboom, Anna Katharina Herta Hirsch
Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT. Chemical communications (Cambridge, England) 60 (7) (2024)
Eleonora Diamanti, Paulo Cesar Telles de Souza, Inda Setyawati, Spyridon Bousis, Leticia Monjas, Lotteke J Y M Swier, Atanaz Shams, Aleksei Tsarenko, Weronika K Stanek, Manuel Jäger, Siewert-Jan Marrink, Dirk Jan Slotboom, Anna Katharina Herta Hirsch
Author Correction: Identification of inhibitors targeting the energy-coupling factor (ECF) transporters. Communications biology 7 (1) (2024)
Franziska Fries, Andreas Martin Kany, Sari Rasheed, Anna Katharina Herta Hirsch, Daniel Krug, Jennifer Herrmann
Correction: Fries et al. Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin A Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. Int. J. Mol. Sci. 2023, 24 , 12791. International journal of molecular sciences 25 (4) (2024)
Alexandra Geißler, Howard Junca, Andreas M Kany, Lena J Daumann, Anna Katharina Herta Hirsch, Dietmar H Pieper, Stephan A Sieber
Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes. Chemical science 15 (30) (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases 10 (3) (2024)
Ioulia Antonia Exapicheidou, Atanaz Shams, Hamza Ibrahim, Aleksei Tsarenko, Michael Backenköhler, Mostafa M Hamed, Eleonora Diamanti, Andrea Volkamer, Dirk J Slotboom, Anna Katharina Herta Hirsch
Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT. Chemical communications (Cambridge, England) 60 (7) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases 10 (3) (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases 10 (3) (2024)
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tiziana Masini, Lais Pessanha De Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M Hodge, Sophie Alvarez, Daan V Bunt, Antoine Lacour, Atanaz Shams, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack den Hartog, Michael Christopher Hutter, Jana Held, Audrey R Odom John, Carsten Wrenger, Anna Katharina Herta Hirsch
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum . ACS infectious diseases 10 (3) (2024)
Walter Hofer, Felix Deschner, Gwenaëlle Jézéquel, Laìs Pessanha de Carvalho, Noran Abdel-Wadood, Linda Pätzold, Steffen Bernecker, Bernd Morgenstern, Andreas Martin Kany, Miriam Große, Marc Stadler, Markus Bischoff, Anna Katharina Herta Hirsch, Jana Held, Jennifer Herrmann, Daniel Krug
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application. Angewandte Chemie (International ed. in English) (2024)
Victor O Gawriljuk, Andre Schutzer Godoy, Rick Oerlemans, Luise A T Welker, Anna Katharina Herta Hirsch, Matthew R Groves
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain. Nature communications 15 (1) (2024)
Olga Metelkina, Jelena Konstantinović, Andreas Klein, Roya Shafiei, Mario Fares, Alaa Alhayek, Samir Yahiaoui, Walid A M Elgaher, Jörg Haupenthal, Alexander Titz, Anna Katharina Herta Hirsch
Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB. Chemical science 15 (33) (2024)
Daan Willocx, Lorenzo Bizzarri, Alaa Alhayek, Deepika Kannan, Patricia Bravo, Boris Illarionov, Katharina Rox, Jonas Lohse, Markus Fischer, Andreas Martin Kany, Hannes Hahne, Matthias Rottmann, Matthias Witschel, Audrey Odom John, Mostafa M Hamed, Eleonora Diamanti, Anna Katharina Herta Hirsch
Targeting Plasmodium falciparum IspD in the Methyl-d-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity. Journal of medicinal chemistry (2024)
Victor O Gawriljuk, Andre Schutzer Godoy, Rick Oerlemans, Luise A T Welker, Anna Katharina Herta Hirsch, Matthew R Groves
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain. Nature communications 15 (1) (2024)
Alexandra Geißler, Howard Junca, Andreas M Kany, Lena J Daumann, Anna Katharina Herta Hirsch, Dietmar H Pieper, Stephan A Sieber
Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes. Chemical science 15 (30) (2024)
Franziska Fries, Andreas Martin Kany, Sari Rasheed, Anna Katharina Herta Hirsch, Daniel Krug, Jennifer Herrmann
Correction: Fries et al. Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin A Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. Int. J. Mol. Sci. 2023, 24 , 12791. International journal of molecular sciences 25 (4) (2024)
Sebastian Mielniczuk, Katharina Hoff, Fady Baselious, Yunqi Li, Jörg Haupenthal, Andreas M Kany, Maria Riedner, Holger Rohde, Katharina Rox, Anna Katharina Herta Hirsch, Isabelle Krimm, Wolfgang Sippl, Ralph Holl
Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity. Journal of medicinal chemistry (2024)
Walter Hofer, Felix Deschner, Gwenaëlle Jézéquel, Laìs Pessanha de Carvalho, Noran Abdel-Wadood, Linda Pätzold, Steffen Bernecker, Bernd Morgenstern, Andreas Martin Kany, Miriam Große, Marc Stadler, Markus Bischoff, Anna Katharina Herta Hirsch, Jana Held, Jennifer Herrmann, Daniel Krug
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application. Angewandte Chemie (International ed. in English) 63 (19) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Serena Della Volpe, Roberta Listro, Francesca Alessandra Ambrosio, Martina Garbagnoli, Pasquale Linciano, Daniela Rossi, Giosuè Costa, Stefano Alcaro, Francesca Vasile, Anna Katharina Herta Hirsch, Simona Collina
Identification of HuR-RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization. ACS medicinal chemistry letters 14 (11) (2023)
Yun Liu, Salma R Ashmawy, Lorenz Latta, Agnes-Valencia Weiss, Alexander F Kiefer, Sarah Nasr, Brigitta Loretz, Anna Katharina Herta Hirsch, Sangeun Lee, Claus-Michael Lehr
pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA. Biomacromolecules (2023)
Philipp Peslalz, Frank Kraus, Flavia Izzo, Anton Bleisch, Yamina El Hamdaoui, Ina Schulz, Andreas Martin Kany, Anna Katharina Herta Hirsch, Kristina Friedland, Bernd Plietker
Selective Activation of a TRPC6 Ion Channel Over TRPC3 by Metalated Type-B Polycyclic Polyprenylated Acylphloroglucinols. Journal of medicinal chemistry (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Eleonora Diamanti, Paulo Cesar Telles de Souza, Inda Setyawati, Spyridon Bousis, Leticia M Gómez, Lotteke J Y M Swier, Atanaz Shams, Aleksei Tsarenko, Weronika K Stanek, Manuel Jäger, Siewert-Jan Marrink, Dirk Jan Slotboom, Anna Katharina Herta Hirsch
Identification of inhibitors targeting the energy-coupling factor (ECF) transporters. Communications biology 6 (1) (2023)
Michael W Mullowney, Katherine R Duncan, Somayah S Elsayed, Neha Garg, Justin Johan Jozias van der Hooft, Nathaniel I Martin, David Meijer, Barbara R Terlouw, Friederike Biermann, Kai Blin, Janani Durairaj, Marina Gorostiola González, Eric J N Helfrich, Florian Huber, Stefan Leopold-Messer, Kohulan Rajan, Tristan de Rond, Jeffrey A van Santen, Maria Sorokina, Marcy J Balunas, Mehdi A Beniddir, Doris A van Bergeijk, Laura M Carroll, Chase M Clark, Djork-Arné Clevert, Chris A Dejong, Chao Du, Scarlet Ferrinho, Francesca Grisoni, Albert Hofstetter, Willem Jespers, Olga V Kalinina, Satria A Kautsar, Hyun Woo Kim, Tiago F Leao, Joleen Masschelein, Evan R Rees, Raphael Reher, Daniel Reker, Philippe Schwaller, Marwin Segler, Michael A Skinnider, Allison S Walker, Egon L Wilighagen, Barbara Zdrazil, Nadine Ziemert, Rebecca J M Goss, Pierre Guyomard, Andrea Volkamer, William H Gerwick, Hyun Uk Kim, Daniel Krug, Gilles P van Wezel, Gerard van Westen, Anna Katharina Herta Hirsch, Roger G Linington, Serina L Robinson, Marnix H Medema
Artificial intelligence for natural product drug discovery. Nature reviews. Drug discovery (2023)
Aylin Berwanger, Saskia C Stein, Andreas Martin Kany, Melissa Gartner, Brigitta Loretz, Claus-Michael Lehr, Anna Katharina Herta Hirsch, Thomas F Schulz, Martin Empting
Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor. Journal of medicinal chemistry (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Jelena Konstantinović, Andreas Martin Kany, Alaa Alhayek, Ahmed S Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf Wolfgang Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna Katharina Herta Hirsch
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections. ACS central science 9 (12) (2023)
Franziska Fries, Andreas Martin Kany, Sari Rasheed, Anna Katharina Herta Hirsch, Daniel Krug, Jennifer Herrmann
Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin a Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. International journal of molecular sciences 24 (16) (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Carsten E Seyfert, Alison V Müller, Danica J Walsh, Joy Birkelbach, Andreas M Kany, Christoph Porten, Biao Yuan, Daniel Krug, Jennifer Herrmann, Thomas C Marlovits, Anna Katharina Herta Hirsch, Daniel Krug
New Genetically Engineered Derivatives of Antibacterial Darobactins Underpin Their Potential for Antibiotic Development. Journal of medicinal chemistry 66 (23) (2023)
Jelena Konstantinović, Andreas Martin Kany, Alaa Alhayek, Ahmed S Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf Wolfgang Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna Katharina Herta Hirsch
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections. ACS central science 9 (12) (2023)
Virgyl Camberlein, Charlotte Fléau, Pierre Sierocki, Lenong Li, Ronan Gealageas, Damien Bosc, Valentin Guillaume, Sandrine Warenghem, Florence Leroux, Melissa Rosell, Keguang Cheng, Laura Medve, Mathilde Prigent, Myriam Decanter, Catherine Piveteau, Alexandre Biela, Maxime Eveque, Julie Dumont, Anastasia Mpakali, Petros Giastas, Adrien Herledan, Cyril Couturier, Jörg Haupenthal, Laetitia Lesire, Anna Katharina Herta Hirsch, Benoit Déprez, Efstratios Stratikos, Marlene Bouvier, Rebecca Deprez-Poulain
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis. Angewandte Chemie (International ed. in English) 61 (39) (2022)
Spyridon Bousis, Steffen Winkler, Jörg Haupenthal, Francesco Fulco, Eleonora Diamanti, Anna Katharina Herta Hirsch
An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay. International journal of molecular sciences 23 (5) (2022)
Alexander F Kiefer, Spyridon Bousis, Mostafa M Hamed, Eleonora Diamanti, Jörg Haupenthal, Anna Katharina Herta Hirsch
Structure-Guided Optimization of Small-Molecule Folate Uptake Inhibitors Targeting the Energy-Coupling Factor Transporters. Journal of medicinal chemistry 65 (13) (2022)
Greta Bagnolini, Beatrice Balboni, Fabrizio Schipani, Dario Gioia, Marina Veronesi, Francesca De Franco, Cansu Kaya, Ravindra P Jumde, Jose Antonio Ortega, Stefania Girotto, Anna Katharina Herta Hirsch, Marinella Roberti, Andrea Cavalli
Identification of RAD51-BRCA2 Inhibitors Using N -Acylhydrazone-Based Dynamic Combinatorial Chemistry. ACS medicinal chemistry letters 13 (8) (2022)
Di Zhu, Sandra Johannsen, Tiziana Masini, Céline Simonin, Jörg Haupenthal, Boris Illarionov, Anastasia Andreas, Mahendra Awale, Robin M Gierse, Tridia van der Laan, Ramon van der Vlag, Rita Nasti, Mael Poizat, Eric Buhler, Norbert Reiling, Daniel Krug, Markus Fischer, Jean-Louis Reymond, Anna Katharina Herta Hirsch
Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening. Chemical science 13 (36) (2022)
Alaa Ibrahim, Sara A Abdel Gaber, Mohamed Fawzi Kabil, Omar A H Ahmed-Farid, Anna Katharina Herta Hirsch, Ibrahim M El-Sherbiny, Maha Nasr
Baicalin lipid nanocapsules for treatment of glioma: characterization, mechanistic cytotoxicity, and pharmacokinetic evaluation. Expert opinion on drug delivery 19 (11) (2022)
Alaa Alhayek, Ahmed S Abdelsamie, Esther Schönauer, Virgyl Camberlein, Evelyn Hutterer, Gernot Posselt, Jamil Serwanja, Constantin Blöchl, Christian G Huber, Jörg Haupenthal, Hans Brandstetter, Silja Wessler, Anna Katharina Herta Hirsch
Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. Journal of medicinal chemistry 65 (19) (2022)
Cansu Kaya, Isabell Walter, Alaa Alhayek, Roya Shafiei, Gwenaëlle Jézéquel, Anastasia Andreas, Jelena Konstantinović, Esther Schönauer, Asfandyar Sikandar, Jörg Haupenthal, Daniel Krug, Hans Brandstetter, Rolf Wolfgang Hartmann, Anna Katharina Herta Hirsch
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa . ACS infectious diseases 8 (5) (2022)
Jehad Hamdy, Nouran Emadeldin, Mostafa M Hamed, Efseveia Frakolaki, Sotirios Katsamakas, Niki Vassilaki, Grigoris Zoidis, Anna Katharina Herta Hirsch, Mohammad Abdel-Halim, Ashraf H Abadi
Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (5) (2022)
Fangfang Chen, Walid A M Elgaher, M Winterhoff, Konrad Büssow, Syed Fakhar-Ul-Hassnain Waqas, E Graner, Y Pires-Afonso, L Casares Perez, Laureano de la Vega, N Sahini, L Czichon, W Zobl, Thomas Zillinger, M Shehata, Stephan Pleschka, H Bähre, C Falk, Alessandro Michelucci, S Schuchardt, Wulf Blankenfeldt, Anna Katharina Herta Hirsch, Frank Pessler
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism. Nature metabolism 4 (5) (2022)
Eleonora Diamanti, Mostafa M Hamed, Antoine Lacour, Patricia Bravo, Boris Illarionov, Markus Fischer, Matthias Rottmann, Matthias Witschel, Anna Katharina Herta Hirsch
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class. ChemMedChem 17 (5) (2022)
Sebastian Walesch, Joy Birkelbach, Gwenaëlle Jézéquel, F P Jake Haeckl, Julian D Hegemann, Thomas Hesterkamp, Anna Katharina Herta Hirsch, Peter Hammann, Daniel Krug
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials. EMBO reports (2022)
Sebastian Walesch, Joy Birkelbach, Gwenaëlle Jézéquel, F P Jake Haeckl, Julian D Hegemann, Thomas Hesterkamp, Anna Katharina Herta Hirsch, Peter Hammann, Daniel Krug
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials. EMBO reports 24 (1) (2022)
Cansu Kaya, Anna Katharina Herta Hirsch
Targeting Extracellular Bacterial Proteases for the Development of Novel Antivirulence Agents. Chimia 76 (5) (2022)
Virgyl Camberlein, Gwenaëlle Jézéquel, Jörg Haupenthal, Anna Katharina Herta Hirsch
The Structures and Binding Modes of Small-Molecule Inhibitors of Pseudomonas aeruginosa Elastase LasB. Antibiotics (Basel, Switzerland) 11 (8) (2022)
David C Rees, Anna Katharina Herta Hirsch, Daniel A Erlanson
Introduction to the themed collection on fragment-based drug discovery. RSC medicinal chemistry 13 (12) (2022)
Sebastian Walesch, Joy Birkelbach, Gwenaëlle Jézéquel, F P Jake Haeckl, Julian D Hegemann, Thomas Hesterkamp, Anna Katharina Herta Hirsch, Peter Hammann, Daniel Krug
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials. EMBO reports 24 (1) (2022)
Cansu Kaya, Jelena Konstantinović, Andreas M Kany, Anastasia Andreas, Jan S Kramer, Steffen Brunst, Lilia Weizel, Marco J Rotter, Denia Frank, Samir Yahiaoui, Daniel Krug, Rolf Wolfgang Hartmann, Jörg Haupenthal, Ewgenij Proschak, Thomas A Wichelhaus, Anna Katharina Herta Hirsch
N -Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. Journal of medicinal chemistry 65 (5) (2022)
Sebastian Walesch, Joy Birkelbach, Gwenaëlle Jézéquel, F P Jake Haeckl, Julian D Hegemann, Thomas Hesterkamp, Anna Katharina Herta Hirsch, Peter Hammann, Daniel Krug
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials. EMBO reports 24 (1) (2022)
Sebastian Walesch, Joy Birkelbach, Gwenaëlle Jézéquel, F P Jake Haeckl, Julian D Hegemann, Thomas Hesterkamp, Anna Katharina Herta Hirsch, Peter Hammann, Daniel Krug
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials. EMBO reports 24 (1) (2022)
Juan Carlos Moreno-López, Alejandro Pérez Paz, Stefano Gottardi, Leonid Solianyk, Jun Li, Leticia Monjas, Anna Katharina Herta Hirsch, Duncan John Mowbray, Meike Stöhr
Unveiling Adatoms in On-Surface Reactions: Combining Scanning Probe Microscopy with van't Hoff Plots. The journal of physical chemistry. C, Nanomaterials and interfaces 125 (18) (2021)
Henni-Karoliina Ropponen, Eleonora Diamanti, Alexandra Siemens, Boris Illarionov, Jörg Haupenthal, Markus Fischer, Matthias Rottmann, Matthias Witschel, Anna Katharina Herta Hirsch
Assessment of the rules related to gaining activity against Gram-negative bacteria. RSC medicinal chemistry 12 (4) (2021)
Katrin Voos, Esther Schönauer, Alaa Alhayek, Jörg Haupenthal, Anastasia Andreas, Daniel Krug, Rolf Wolfgang Hartmann, Katharina Häussermann, Anna Katharina Herta Hirsch, Christian Ducho
Phosphonate as a Stable Zinc-Binding Group for "Pathoblocker" Inhibitors of Clostridial Collagenase H (ColH). ChemMedChem 16 (8) (2021)
Menka Drost, Eleonora Diamanti, Kathrin Fuhrmann, Adriely Goes, Atanaz Shams, Jörg Haupenthal, Marcus Koch, Anna Katharina Herta Hirsch, Molly M Stevens
Bacteriomimetic Liposomes Improve Antibiotic Activity of a Novel Energy-Coupling Factor Transporter Inhibitor. Pharmaceutics 14 (1) (2021)
Christian Schütz, Duy-Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Röhrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus-Michael Lehr, Martin Empting
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (12) (2021)
Samir Yahiaoui, Katrin Voos, Jörg Haupenthal, Thomas A Wichelhaus, Denia Frank, Lilia Weizel, Marco Rotter, Steffen Brunst, Jan S Kramer, Ewgenij Proschak, Christian Ducho, Anna Katharina Herta Hirsch
N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa. RSC medicinal chemistry 12 (10) (2021)
Henni-Karoliina Ropponen, Chantal D Bader, Eleonora Diamanti, Boris Illarionov, Matthias Rottmann, Markus Fischer, Matthias Witschel, Rolf Müller, Anna Katharina Herta Hirsch
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity. ChemMedChem 16 (13) (2021)
Eva Zahorska, Sakonwan Kuhaudomlarp, Saverio Minervini, Sultaan Yousaf, Martin Lepsik, Thorsten Kinsinger, Anna Katharina Herta Hirsch, Anne Imberty, Alexander Titz
A rapid synthesis of low-nanomolar divalent LecA inhibitors in four linear steps from d-galactose pentaacetate. Chemical communications (Cambridge, England) 56 (62) (2021)
Ravindra P Jumde, Melissa Guardigni, Robin M Gierse, Alaa Alhayek, Di Zhu, Zhoor Hamid, Sandra Johannsen, Walid A M Elgaher, Philipp J Neusens, Christian Nehls, Jörg Haupenthal, Norbert Reiling, Anna Katharina Herta Hirsch
Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase. Chemical science 12 (22) (2021)
Jörg Haupenthal, Yannik Kautz, Walid A M Elgaher, Linda Pätzold, Teresa Röhrig, Matthias W Laschke, Thomas Tschernig, Anna Katharina Herta Hirsch, Vadim Molodtsov, Katsuhiko S Murakami, Rolf Wolfgang Hartmann, Markus Bischoff
Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus-Based Wound Infection Model in SKH1 Mice. ACS infectious diseases 6 (10) (2020)
Zhangping Xiao, Deng Chen, Shanshan Song, Ramon van der Vlag, Petra E van der Wouden, Ronald van Merkerk, Robbert H Cool, Anna Katharina Herta Hirsch, Barbro N Melgert, Wim J Quax, Gerrit J Poelarends, Frank J Dekker
7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor. Journal of medicinal chemistry 63 (20) (2020)
Jelena Konstantinović, Samir Yahiaoui, Alaa Alhayek, Jörg Haupenthal, Esther Schönauer, Anastasia Andreas, Andreas M Kany, Rolf Müller, Jesko Koehnke, Fabian K Berger, Markus Bischoff, Rolf Wolfgang Hartmann, Katharina Häussermann, Anna Katharina Herta Hirsch
N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases. Journal of medicinal chemistry 63 (15) (2020)
Alwin M Hartman, Varsha R Jumde, Walid A M Elgaher, Evelien M Te Poele, Lubbert Dijkhuizen, Anna Katharina Herta Hirsch
Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar-Based Molecules that Target Bacterial Glucosyltransferase. ChemMedChem 16 (1) (2020)
Alexander Axer, Ravindra P Jumde, Sebastian Adam, Andreas Faust, Michael Schäfers, Manfred Fobker, Jesko Koehnke, Anna Katharina Herta Hirsch, Ryan Gilmour
Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design. Chemical science 12 (4) (2020)
Fraser Hof, Anna Katharina Herta Hirsch
François Diederich - In Memoriam*. ChemMedChem 16 (1) (2020)
Federica Mancini, M Yagiz Unver, Walid A M Elgaher, Varsha R Jumde, Alaa Alhayek, Peer Lukat, Jennifer Herrmann, Martin D Witte, Matthias Köck, Wulf Blankenfeldt, Rolf Müller, Anna Katharina Herta Hirsch
Protein-Templated Hit Identification through an Ugi Four-Component Reaction*. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (64) (2020)
Nathalie Erdeljac, Christian Thiehoff, Ravindra P Jumde, Constantin G Daniliuc, Sandra Höppner, Andreas Faust, Anna Katharina Herta Hirsch, Ryan Gilmour
Validating the 1,2-Difluoro Motif As a Hybrid Bioisostere of CF3 and Et Using Matrix Metalloproteinases As Structural Probes. Journal of medicinal chemistry 63 (11) (2020)
Ignacio Piquero-Zulaica, Jun Li, Zakaria M Abd El-Fattah, Leonid Solianyk, Iker Gallardo, Leticia Monjas, Anna Katharina Herta Hirsch, Andrés Arnau, José Enrique Ortega, Meike Stöhr, Jorge Lobo-Checa
Surface state tunable energy and mass renormalization from homothetic quantum dot arrays. Nanoscale 11 (48) (2019)
Ramon van der Vlag, M Yagiz Unver, Tommaso Felicetti, Aleksandra Twarda-Clapa, Fatima Kassim, Cagdas Ermis, Constantinos G Neochoritis, Bogdan M Musielak, Beata Labuzek, Alexander S S Dömling, Tad A Holak, Anna Katharina Herta Hirsch
Optimized Inhibitors of MDM2 via an Attempted Protein-Templated Reductive Amination. ChemMedChem 15 (4) (2019)
Nico Schmidt, Jun Li, Stefano Gottardi, Juan Carlos Moreno-Lopez, Mihaela Enache, Leticia Monjas, Ramon van der Vlag, Remco W A Havenith, Anna Katharina Herta Hirsch, Meike Stöhr
Comparing the Self-Assembly of Sexiphenyl-Dicarbonitrile on Graphite and Graphene on Cu(111). Chemistry (Weinheim an der Bergstrasse, Germany) 25 (19) (2019)
Deka Prismawan, Ramon van der Vlag, Hao Guo, Frank J Dekker, Anna Katharina Herta Hirsch
Replacement of an Indole Scaffold Targeting Human 15-Lipoxygenase-1 Using Combinatorial Chemistry. Helvetica chimica acta 102 (5) (2019)
Chakravarthi Simhadri, Kevin D Daze, Sarah F Douglas, Natalia Milosevich, Leticia Monjas, Amarjot Dev, Tyler M Brown, Anna Katharina Herta Hirsch, Jeremy E Wulff, Fraser Hof
Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists. ChemMedChem 14 (15) (2019)
Alwin M Hartman, Robin M Gierse, Anna Katharina Herta Hirsch
Protein-Templated Dynamic Combinatorial Chemistry: Brief Overview and Experimental Protocol. European journal of organic chemistry 2019 (22) (2019)
Yun Liu, Marc C A Stuart, Eric Buhler, Anna Katharina Herta Hirsch
Dynamic Proteoids Generated From Dipeptide-Based Monomers. Macromolecular rapid communications 39 (13) (2018)
M Yagiz Unver, Robin M Gierse, Harry Ritchie, Anna Katharina Herta Hirsch
Druggability Assessment of Targets Used in Kinetic Target-Guided Synthesis. Journal of medicinal chemistry 61 (21) (2018)
Varsha R Jumde, Milon Mondal, Robin M Gierse, M Yagiz Unver, Francesca Magari, Roos C W van Lier, Andreas Heine, Gerhard Klebe, Anna Katharina Herta Hirsch
Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin. ChemMedChem 13 (21) (2018)
Iwona Łozińska, Aleksandra Świerczyńska, Zuzanna Molęda, Alwin M Hartman, Anna Katharina Herta Hirsch, Zbigniew Czarnocki
Donepezil-melatonin hybrids as butyrylcholinesterase inhibitors: Improving binding affinity through varying mode of linking fragments. Archiv der Pharmazie 351 (11) (2018)
Evelien M Te Poele, Tim Devlamynck, Manuel Jäger, Gerrit J Gerwig, Davy Van de Walle, Koen Dewettinck, Anna Katharina Herta Hirsch, Johannis P Kamerling, Wim Soetaert, Lubbert Dijkhuizen
Glucansucrase (mutant) enzymes from Lactobacillus reuteri 180 efficiently transglucosylate Stevia component rebaudioside A, resulting in a superior taste. Scientific reports 8 (1) (2018)
Leticia Monjas, Lotteke J Y M Swier, Inda Setyawati, Dirk J Slotboom, Anna Katharina Herta Hirsch
Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine. ChemMedChem 12 (20) (2017)
Alessio Marcozzi, Tiziana Masini, Di Zhu, Diego Pesce, Boris Illarionov, Markus Fischer, Andreas Herrmann, Anna Katharina Herta Hirsch
Phage Display on the Anti-infective Target 1-Deoxy-d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor. Chembiochem : a European journal of chemical biology 19 (1) (2017)

Anna Katharina Herta Hirsch.css-eqlu8i{font-size:small;padding-left:4px;} (A K H Hirsch, Anna K H Hirsch)

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Anna Katharina Herta Hirsch (A K H Hirsch, Anna K H Hirsch)