Matthias Engel

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Topics

Multidrug Resistant

Silver Nanoparticles

Top Venues

Archiv der Pharmazie

Journal of medicinal chemistry

Future medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, Shun-Hua Chen, Hsin-Chieh Lin, Dalia S El-Gamil, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity. Future medicinal chemistry 16 (12) (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie (2024)
Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, Shun-Hua Chen, Hsin-Chieh Lin, Dalia S El-Gamil, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity. Future medicinal chemistry 16 (12) (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie 357 (4) (2024)
Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, Shun-Hua Chen, Hsin-Chieh Lin, Dalia S El-Gamil, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity. Future medicinal chemistry 16 (12) (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie 357 (4) (2024)
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, Yu-Chieh Su, Ming-Hua Shiao, Gary A Piazza, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N -Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents. Cancers 16 (11) (2024)
Habiba G Aboelfotouh, Mennatallah Abdallah, Hend Khalifa, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N 1 -Benzoylated 5-(4-pyridinyl)indazole-based kinase inhibitors: Attaining haspin and Clk4 selectivity via modulation of the benzoyl substituents. Archiv der Pharmazie 357 (6) (2024)
Habiba G Aboelfotouh, Mennatallah Abdallah, Hend Khalifa, Youssef Aboushady, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N 1 -Benzoylated 5-(4-pyridinyl)indazole-based kinase inhibitors: Attaining haspin and Clk4 selectivity via modulation of the benzoyl substituents. Archiv der Pharmazie (2024)
Hend Khalifa, Sari Rasheed, Jörg Haupenthal, Jennifer Herrmann, Yasmine M Mandour, Ashraf H Abadi, Matthias Engel, Rolf Müller, Anna K H Hirsch, Mohammad Abdel-Halim, Mostafa M Hamed
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents. Archiv der Pharmazie 357 (4) (2024)
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, Yu-Chieh Su, Ming-Hua Shiao, Gary A Piazza, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim
N -Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents. Cancers 16 (11) (2024)
Reem K Fathalla, Matthias Engel, Christian Ducho
Targeting the binding pocket of the fluorophore 8-anilinonaphthalene-1-sulfonic acid in the bacterial enzyme MurA. Archiv der Pharmazie (2023)
Suzan Fangary, Mohammad Abdel-Halim, Reem K Fathalla, Raghda Hassan, Noha Farag, Matthias Engel, Samar Mansour, Salma N Tammam
Nanoparticle Fraught Liposomes: A Platform for Increased Antibiotic Selectivity in Multidrug Resistant Bacteria. Molecular pharmaceutics 19 (9) (2022)
Sarah S Darwish, Po-Jen Chen, Mostafa M Hamed, Reem A Wagdy, Shun-Hua Chen, Ashraf H Abadi, Mohammad Abdel-Halim, Tsong-Long Hwang, Matthias Engel
Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Reem K Fathalla, Wolfgang Fröhner, Chantal D Bader, Patrick D Fischer, Charlotte Dahlem, Deep Chatterjee, Sebastian Mathea, Alexandra K Kiemer, Haribabu Arthanari, Rolf Müller, Mohammad Abdel-Halim, Christian Ducho, Matthias Engel
Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA. Journal of medicinal chemistry 65 (21) (2022)
Ahmed K ElHady, Dalia S El-Gamil, Ashraf H Abadi, Mohammad Abdel-Halim, Matthias Engel
An overview of cdc2-like kinase 1 (Clk1) inhibitors and their therapeutic indications. Medicinal research reviews (2022)
Mohammad Abdel-Halim, Sara Sigler, Nora A S Racheed, Amr Hefnawy, Reem K Fathalla, Mennatallah A Hammam, Ahmed Maher, Yulia Maxuitenko, Adam B Keeton, Rolf Wolfgang Hartmann, Matthias Engel, Gary A Piazza, Ashraf H Abadi
From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity. Journal of medicinal chemistry 64 (8) (2021)
Youssef Aboushady, Moustafa Gabr, Ahmed K ElHady, Mohamed Salah, Ashraf H Abadi, Gerrit Wilms, Walter Becker, Mohammad Abdel-Halim, Matthias Engel
Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases. ACS chemical neuroscience 12 (22) (2021)
Benoît Bestgen, Isabelle Krimm, Irina Kufareva, Ahmed Ashraf Moustafa Kamal, Wei-Guang Seetoh, Chris Abell, Rolf Wolfgang Hartmann, Ruben Abagyan, Claude Cochet, Marc Le Borgne, Matthias Engel, Thierry Lomberget
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site. Journal of medicinal chemistry 62 (4) (2019)
Benoît Bestgen, Irina Kufareva, Wei-Guang Seetoh, Chris Abell, Rolf Wolfgang Hartmann, Ruben Abagyan, Marc Le Borgne, Odile Filhol-Cochet, Claude Cochet, Thierry Lomberget, Matthias Engel
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action. Journal of medicinal chemistry 62 (4) (2019)
Mohammad Abdel-Halim, Ashraf H Abadi, Matthias Engel
Design and synthesis of novel 1,3,5-triphenyl pyrazolines as potential anti-inflammatory agents through allosteric inhibition of protein kinase Czeta (PKCζ). MedChemComm 9 (6) (2018)
Mohamed Salah, Mohammad Abdel-Halim, Matthias Engel
Design and synthesis of conformationally constraint Dyrk1A inhibitors by creating an intramolecular H-bond involving a benzothiazole core. MedChemComm 9 (6) (2018)
Ahmed K ElHady, Mohammad Abdel-Halim, Ashraf H Abadi, Matthias Engel
Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins. Journal of medicinal chemistry 60 (13) (2017)
Mostafa M Hamed, Sarah S Darwish, Jennifer Herrmann, Ashraf H Abadi, Matthias Engel
First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents. Journal of medicinal chemistry 60 (7) (2017)