Axel Leppert

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Topics

Mass Spectrometry

Endoplasmic Reticulum

Single Molecule

Top Venues

Protein science : a publication of the Protein Society

Communications biology

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Axel Leppert, Jianhui Feng, Vaida Railaite, Tomas Bohn Pessatti, Carmine P Cerrato, Cecilia Mörman, Hannah Osterholz, David P Lane, Filipe R N C Maia, Markus B Linder, Anna Rising, Michael Landreh
Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions. Journal of the American Chemical Society 146 (28) (2024)
Axel Leppert, Jianhui Feng, Vaida Railaite, Tomas Bohn Pessatti, Carmine P Cerrato, Cecilia Mörman, Hannah Osterholz, David P Lane, Filipe R N C Maia, Markus B Linder, Anna Rising, Michael Landreh
Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions. Journal of the American Chemical Society 146 (28) (2024)
Axel Leppert, Jianhui Feng, Vaida Railaite, Tomas Bohn Pessatti, Carmine P Cerrato, Cecilia Mörman, Hannah Osterholz, David P Lane, Filipe R N C Maia, Markus B Linder, Anna Rising, Michael Landreh
Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions. Journal of the American Chemical Society 146 (28) (2024)
Gefei Chen, Yu Wang, Zihan Zheng, Wangshu Jiang, Axel Leppert, Xueying Zhong, Anna Belorusova, Gregg Siegal, Caroline Jegerschöld, Philip J B Koeck, Axel Abelein, Hans Hebert, Stefan D Knight, Jan Johansson
Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain. Protein science : a publication of the Protein Society 33 (7) (2024)
Gefei Chen, Yu Wang, Zihan Zheng, Wangshu Jiang, Axel Leppert, Xueying Zhong, Anna Belorusova, Gregg Siegal, Caroline Jegerschöld, Philip J B Koeck, Axel Abelein, Hans Hebert, Stefan D Knight, Jan Johansson
Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain. Protein science : a publication of the Protein Society 33 (7) (2024)
Axel Leppert, Jianhui Feng, Vaida Railaite, Tomas Bohn Pessatti, Carmine P Cerrato, Cecilia Mörman, Hannah Osterholz, David P Lane, Filipe R N C Maia, Markus B Linder, Anna Rising, Michael Landreh
Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions. Journal of the American Chemical Society (2024)
Cagla Sahin, Axel Leppert, Michael Landreh
Advances in mass spectrometry to unravel the structure and function of protein condensates. Nature protocols (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Deike J Omnus, Matthias J Fink, Aswathy Kallazhi, Maria Xandri Zaragoza, Axel Leppert, Michael Landreh, Kristina Jonas
The heat shock protein LarA activates the Lon protease in response to proteotoxic stress. Nature communications 14 (1) (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Mihkel Saluri, Axel Leppert, Genis Valentin Gese, Cagla Sahin, Dilraj Lama, Margit Kaldmäe, Gefei Chen, Arne Elofsson, Timothy M Allison, Marie Arsenian Henriksson, Jan Johansson, David Philip Lane, B Martin Hällberg, Michael Landreh
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. PNAS nexus 2 (2) (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Axel Leppert, Helen Poska, Michael Landreh, Axel Abelein, Gefei Chen, Jan Johansson
A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain. Protein science : a publication of the Protein Society (2023)
Carmine P Cerrato, Axel Leppert, Yue Sun, David P Lane, Marie Arsenian-Henriksson, Ali Miserez, Michael Landreh
Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry. Analytical chemistry (2023)
Axel Leppert, Helen Poska, Michael Landreh, Axel Abelein, Gefei Chen, Jan Johansson
A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain. Protein science : a publication of the Protein Society (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Axel Leppert, Helen Poska, Michael Landreh, Axel Abelein, Gefei Chen, Jan Johansson
A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain. Protein science : a publication of the Protein Society (2023)
Mihkel Saluri, Axel Leppert, Genis Valentin Gese, Cagla Sahin, Dilraj Lama, Margit Kaldmäe, Gefei Chen, Arne Elofsson, Timothy M Allison, Marie Arsenian Henriksson, Jan Johansson, David Philip Lane, B Martin Hällberg, Michael Landreh
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. PNAS nexus 2 (2) (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Axel Leppert, Helen Poska, Michael Landreh, Axel Abelein, Gefei Chen, Jan Johansson
A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain. Protein science : a publication of the Protein Society (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Axel Leppert, Gefei Chen, Danai Lianoudaki, Chloe Williams, Xueying Zhong, Jonathan D Gilthorpe, Michael Landreh, Jan Johansson
ATP-independent molecular chaperone activity generated under reducing conditions. Protein science : a publication of the Protein Society 31 (8) (2022)
Axel Leppert, Ann Tiiman, Nina Kronqvist, Michael Landreh, Axel Abelein, Vladana Vukojevic, Jan Johansson
Smallest Secondary Nucleation Competent Aβ Aggregates Probed by an ATP-Independent Molecular Chaperone Domain. Biochemistry 60 (9) (2021)
Mia L Abramsson, Cagla Sahin, Jonathan T S Hopper, Rui M M Branca, Jens Danielsson, Mingming Xu, Shane A Chandler, Nicklas Österlund, Leopold L Ilag, Axel Leppert, Joana Costeira-Paulo, Lisa Lang, Kaare Teilum, Arthur D Laganowsky, Justin L P Benesch, Mikael Oliveberg, Carol V Robinson, Erik G Marklund, Timothy M Allison, Jakob Rahr Winther, Michael Landreh
Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry. JACS Au 1 (12) (2021)
Gefei Chen, Yuniesky Andrade-Talavera, Simone Tambaro, Axel Leppert, Harriet E Nilsson, Xueying Zhong, Michael Landreh, Per Nilsson, Hans Hebert, Henrik Biverstål, André Fisahn, Axel Abelein, Jan Johansson
Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro. Communications biology 3 (1) (2020)
Simone Tambaro, Lorena Galan-Acosta, Axel Leppert, Gefei Chen, Henrik Biverstål, Jenny Presto, Per Nilsson, Jan Johansson
Blood-brain and blood-cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice. The Journal of biological chemistry 294 (8) (2018)