Gefei Chen

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 24

Top Topics

Tissue Engineering

Endoplasmic Reticulum

Single Molecule

Top Venues

Nature communications

Communications biology

Neural regeneration research

This page only lists publications with an associated author ORCID identifier.

Publications

Gefei Chen, Jan Johansson
Potential of molecular chaperones for treating Alzheimer's disease. Neural regeneration research 19 (11) (2024)
Gefei Chen, Jan Johansson
Potential of molecular chaperones for treating Alzheimer's disease. Neural regeneration research 19 (11) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Gefei Chen, Yu Wang, Zihan Zheng, Wangshu Jiang, Axel Leppert, Xueying Zhong, Anna Belorusova, Gregg Siegal, Caroline Jegerschöld, Philip J B Koeck, Axel Abelein, Hans Hebert, Stefan D Knight, Jan Johansson
Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain. Protein science : a publication of the Protein Society 33 (7) (2024)
Gefei Chen, Yu Wang, Zihan Zheng, Wangshu Jiang, Axel Leppert, Xueying Zhong, Anna Belorusova, Gregg Siegal, Caroline Jegerschöld, Philip J B Koeck, Axel Abelein, Hans Hebert, Stefan D Knight, Jan Johansson
Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain. Protein science : a publication of the Protein Society 33 (7) (2024)
Gefei Chen, Jan Johansson
Potential of molecular chaperones for treating Alzheimer's disease. Neural regeneration research 19 (11) (2024)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Mihkel Saluri, Axel Leppert, Genis Valentin Gese, Cagla Sahin, Dilraj Lama, Margit Kaldmäe, Gefei Chen, Arne Elofsson, Timothy M Allison, Marie Arsenian Henriksson, Jan Johansson, David Philip Lane, B Martin Hällberg, Michael Landreh
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. PNAS nexus 2 (2) (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Mihkel Saluri, Axel Leppert, Genis Valentin Gese, Cagla Sahin, Dilraj Lama, Margit Kaldmäe, Gefei Chen, Arne Elofsson, Timothy M Allison, Marie Arsenian Henriksson, Jan Johansson, David Philip Lane, B Martin Hällberg, Michael Landreh
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. PNAS nexus 2 (2) (2023)
Xingmei Qi, Yu Wang, Hairui Yu, Ruifang Liu, Axel Leppert, Zihan Zheng, Xueying Zhong, Zhen Jin, Han Wang, Xiaoli Li, Xiuzhe Wang, Michael Landreh, Ludmilla A Morozova-Roche, Jan Johansson, Sidong Xiong, Igor A Iashchishyn, Gefei Chen
Spider Silk Protein Forms Amyloid-Like Nanofibrils through a Non-Nucleation-Dependent Polymerization Mechanism. Small (Weinheim an der Bergstrasse, Germany) (2023)
Axel Leppert, Gefei Chen, Dilraj Lama, Cagla Sahin, Vaida Railaite, Olga Shilkova, Tina Arndt, Erik G Marklund, David P Lane, Anna Rising, Michael Landreh
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain. Nano letters (2023)
Gefei Chen, Axel Leppert, Helen Poska, Harriet E Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation. Communications biology 6 (1) (2023)
Xueying Zhong, Rakesh Kumar, Yu Wang, Henrik Biverstål, Caroline Ingeborg Jegerschöld, Philip J B Koeck, Jan Johansson, Axel Abelein, Gefei Chen
Amyloid Fibril Formation of Arctic Amyloid-β 1-42 Peptide is Efficiently Inhibited by the BRICHOS Domain. ACS chemical biology 17 (8) (2022)
Gefei Chen, Yuniesky Andrade-Talavera, Xueying Zhong, Sameer Hassan, Henrik Biverstål, Helen Poska, Axel Abelein, Axel Leppert, Nina Kronqvist, Anna Rising, Hans Hebert, Philip J B Koeck, André Fisahn, Jan Johansson
Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue. RSC chemical biology 3 (11) (2022)
Tina Arndt, Kristaps Jaudzems, Olga Shilkova, Juanita Francis, Mathias Johansson, Peter R Laity, Cagla Sahin, Urmimala Chatterjee, Nina Kronqvist, Edgar Barajas-Ledesma, Rakesh Kumar, Gefei Chen, Roger Strömberg, Axel Abelein, Maud Langton, Michael Landreh, Andreas Barth, Chris Holland, Jan Johansson, Anna Rising
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform. Nature communications 13 (1) (2022)
Xue Li, Xingmei Qi, Yu-Ming Cai, Yuan Sun, Rui Wen, Rui Zhang, Jan Johansson, Qing Meng, Gefei Chen
Customized Flagelliform Spidroins Form Spider Silk-like Fibers at pH 8.0 with Outstanding Tensile Strength. ACS biomaterials science & engineering 8 (1) (2021)