Christopher A LeClair

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 18

Top Venues

Journal of the American Chemical Society

The Journal of biological chemistry

Analytical chemistry

ACS chemical biology

National Center for Advancing Translational Sciences

University of Virginia (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Center for Advancing Translational Sciences

United States

Team Leader :: Analytical Chemistry

Education History

University of Virginia

United States

PHD :: Chemistry

Publications

Sitanshu S Singh, Raul Calvo, Anju Kumari, Rushikesh V Sable, Yuhong Fang, Dingyin Tao, Xin Hu, Sarah Gray Castle, Saifun Nahar, Dandan Li, Emily Major, Tino W Sanchez, Rintaro Kato, Xin Xu, Jian Zhou, Liang Liu, Christopher A LeClair, Anton Simeonov, Bolormaa Baljinnyam, Mark J Henderson, Juan Jose Marugan, Rushikesh Sable
Fatty acid derivatization and cyclization of the immunomodulatory peptide RP-182 targeting CD206high macrophages improves anti-tumor activity. Molecular cancer therapeutics (2024)
McKenna C Crawford, Deepika R Tripu, Samuel A Barritt, Yihang Jing, Diamond Gallimore, Stephen C Kales, Natarajan V Bhanu, Ying Xiong, Yuhong Fang, Kamaria A T Butler, Christopher A LeClair, Nathan P Coussens, Anton Simeonov, Benjamin A Garcia, Christian C Dibble, Jordan L Meier
Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors. ACS chemical biology (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Wenjing Yan, Yongwang Zhong, Xin Hu, Tuan Xu, Yinghua Zhang, Stephen Kales, Yanyan Qu, Daniel C Talley, Bolormaa Baljinnyam, Christopher A LeClair, Anton Simeonov, Brian M Polster, Ruili Huang, Yihong Ye, Ganesha Rai, Mark J Henderson, Dingyin Tao, Shengyun Fang
Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes. Nature communications 14 (1) (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Jessica Ettedgui, Burchelle Blackman, Natarajan Raju, Samuel A Kotler, Eduard Y Chekmenev, Boyd M Goodson, Hellmut Merkle, Carolyn C Woodroofe, Christopher A LeClair, Murali C Krishna, Rolf E Swenson
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1- 13 C]-Pyruvate. Journal of the American Chemical Society 146 (1) (2023)
Victor Clausse, Yuhong Fang, Dingyin Tao, Harichandra D Tagad, Hongmao Sun, Yuhong Wang, Surendra Karavadhi, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Christopher A LeClair, Rebecca Eells, Min Shen, Samarjit Patnaik, Ettore Appella, Nathan P Coussens, Matthew D Hall, Daniel H Appella
Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen. ACS pharmacology & translational science 5 (10) (2022)
Shayan G Borhani, Max Z Levine, Lauren R H Krumpe, Jennifer Wilson, Curtis J Henrich, Barry R Oâ Keefe, Donald Lo, Gurusingham Sittampalam, Alexander G Godfrey, R Dwayne Lunsford, Venkata Mangalampalli, Dingyin Tao, Christopher A LeClair, Aaron Thole, Douglas Frey, James Swartz, Govind Rao
An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics. bioRxiv : the preprint server for biology (2022)
Yu Chen, Carlos A Tristan, Lu Chen, Vukasin M Jovanovic, Claire Malley, Pei-Hsuan Chu, Seungmi Ryu, Tao Deng, Pinar Ormanoglu, Dingyin Tao, Yuhong Fang, Jaroslav Slamecka, Hyenjong Hong, Christopher A LeClair, Sam Michael, Christopher P Austin, Anton Simeonov, Ilyas Singeç
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. Nature methods 18 (5) (2021)
Li Liu, Manshu Tang, Rajan Pragani, Frank G Whitby, Ya-Qin Zhang, Bijina Balakrishnan, Yuhong Fang, Surendra Karavadhi, Dingyin Tao, Christopher A LeClair, Matthew D Hall, Juan Jose Marugan, Matthew Boxer, Min Shen, Christopher P Hill, Kent Lai, Samarjit Patnaik
Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. Journal of medicinal chemistry 64 (18) (2021)
Andrew P Burns, Ya-Qin Zhang, Tuan Xu, Zhengxi Wei, Qin Yao, Yuhong Fang, Valeriu Cebotaru, Menghang Xia, Matthew D Hall, Ruili Huang, Anton Simeonov, Christopher A LeClair, Dingyin Tao
A Universal and High-Throughput Proteomics Sample Preparation Platform. Analytical chemistry 93 (24) (2021)
Dingyin Tao, William Leister, Wenwei Huang, Asaf Alimardanov, Christopher A LeClair
Facile High-Performance Liquid Chromatography Mass Spectrometry Method for Analysis of Cyclocreatine and Phosphocyclocreatine in Complex Mixtures of Amino Acids. Journal of agricultural and food chemistry 67 (25) (2019)
Victor Clausse, Dingyin Tao, Subrata Debnath, Yuhong Fang, Harichandra D Tagad, Yuhong Wang, Hongmao Sun, Christopher A LeClair, Sharlyn J Mazur, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Rebecca Eells, Lynn K Baker, Mark J Henderson, Martin R Webb, Min Shen, Matthew D Hall, Ettore Appella, Daniel H Appella, Nathan P Coussens
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. The Journal of biological chemistry 294 (46) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christopher A LeClair