Benjamin E Willcox

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 12

Top Topics

Helicobacter Pylori Infection

Dendritic Cells

Immune Response

Top Venues

RSC medicinal chemistry

Journal of medicinal chemistry

Nature communications

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Qin Xu, Maria Sharif, Edward James, Jack O Dismorr, James H R Tucker, Benjamin E Willcox, Youcef Mehellou
Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells. RSC medicinal chemistry 15 (7) (2024)
Qin Xu, Maria Sharif, Edward James, Jack O Dismorr, James H R Tucker, Benjamin E Willcox, Youcef Mehellou
Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells. RSC medicinal chemistry 15 (7) (2024)
Mohindar Murugesh Karunakaran, Hariharan Subramanian, Yiming Jin, Fiyaz Mohammed, Brigitte Kimmel, Claudia Juraske, Lisa Starick, Anna Nöhren, Nora Länder, Carrie R Willcox, Rohit Singh, Wolfgang W A Schamel, Viacheslav O Nikolaev, Volker Kunzmann, Andrew J Wiemer, Benjamin E Willcox, Thomas Herrmann
A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human γδ T cell phosphoantigen sensing. Nature communications 14 (1) (2023)
Christelle Harly, Stephen Paul Joyce, Charlotte Domblides, Thomas Bachelet, Vincent Pitard, Charlotte Mannat, Angela Pappalardo, Lionel Couzi, Sonia Netzer, Layal Massara, Emilie Obre, Omar Hawchar, Lydia Lartigue, Stéphane Claverol, Carla Cano, Jean-François Moreau, Isabelle Mahouche, Isabelle Soubeyran, Rodrigue Rossignol, Benoit Viollet, Carrie R Willcox, Fiyaz Mohammed, Benjamin E Willcox, Benjamin Faustin, Julie Déchanet-Merville
Human γδ T cell sensing of AMPK-dependent metabolic tumor reprogramming through TCR recognition of EphA2. Science immunology 6 (61) (2022)
Qin Xu, Taher E Taher, Elizabeth Ashby, Maria Sharif, Benjamin E Willcox, Youcef Mehellou
Generation of Stable Isopentenyl Monophosphate Aryloxy Triester Phosphoramidates as Activators of Vγ9Vδ2 T Cells. ChemMedChem 16 (15) (2021)
Carrie R Willcox, Fiyaz Mohammed, Benjamin E Willcox
The distinct MHC-unrestricted immunobiology of innate-like and adaptive-like human γδ T cell subsets-Nature's CAR-T cells. Immunological reviews 298 (1) (2020)
Hachemi Kadri, Taher E Taher, Qin Xu, Maria Sharif, Elizabeth Ashby, Richard T Bryan, Benjamin E Willcox, Youcef Mehellou
Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses. Journal of medicinal chemistry 63 (19) (2020)
Sharyn Thomas, Fiyaz Mohammed, Rogier M Reijmers, Annemarie L Woolston, Theresa Stauss, Alan Kennedy, David R Stirling, Angelika Holler, Louisa Green, David T Jones, Katherine K Matthews, David A Price, Benjamin M Chain, Mirjam H M Heemskerk, Emma Catherine Morris, Benjamin E Willcox, Hans J Stauss
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function. Nature communications 10 (1) (2019)
Benjamin E Willcox, Carrie R Willcox
γδ TCR ligands: the quest to solve a 500-million-year-old mystery. Nature immunology 20 (2) (2019)
Martin S Davey, Roshni Malde, Rory C Mykura, Alfie T Baker, Taher E Taher, Cécile S Le Duff, Benjamin E Willcox, Youcef Mehellou
Synthesis and Biological Evaluation of ( E)-4-Hydroxy-3-methylbut-2-enyl Phosphate (HMBP) Aryloxy Triester Phosphoramidate Prodrugs as Activators of Vγ9/Vδ2 T-Cell Immune Responses. Journal of medicinal chemistry 61 (5) (2018)
Jianmin J Zuo, Carrie R Willcox, Fiyaz Mohammed, Martin S Davey, Stuart Hunter, Kabir Khan, Ayman Antoun Reyad, Poonam Katakia, Joanne Croudace, Charlotte Inman, Helen Parry, David Briggs, Ram Malladi, Benjamin E Willcox, Paul A H Moss
A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding. Science signaling 10 (481) (2017)
Mahboob Salim, Timothy J Knowles, Alfie T Baker, Martin S Davey, Mark Jeeves, Pooja Sridhar, John Wilkie, Carrie R Willcox, Hachemi Kadri, Taher E Taher, Pierre Vantourout, Adrian Hayday, Youcef Mehellou, Fiyaz Mohammed, Benjamin E Willcox
BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain. ACS chemical biology 12 (10) (2017)