Mirjam H M Heemskerk (Mirjam H Heemskerk)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 25

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Nature communications

Blood advances

NPJ vaccines

Leiden University Medical Center

Veterinary Faculty (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leiden University Medical Center

Netherlands

Associate professor, Head of Laboratory of experiemtnal hematology :: Hematology

Education History

Veterinary Faculty Sep 01 1990 - Sep 01 1994

Netherlands

PHD :: Immunology

Universiteit Leiden Sep 01 1985 - Jun 01 1990

Netherlands

MSC :: Biomedische wetenschappen

Publications

Margaretha L M Prins, Geert V T Roozen, Cilia R Pothast, Wesley Huisman, Rob van Binnendijk, Gerco den Hartog, Vincent P Kuiper, Corine Prins, Jacqueline J Janse, Olivia A C Lamers, Jan Pieter R Koopman, Annelieke C Kruithof, Ingrid M C Kamerling, Romy C Dijkland, Alicia C de Kroon, Shohreh Azimi, Mariet C W Feltkamp, Marjan Kuijer, Simon P Jochems, Mirjam H M Heemskerk, Frits Richard Rosendaal, Meta Roestenberg, Leo G Visser, Anna H E Roukens
Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial. NPJ vaccines 9 (1) (2024)
J H Frederik Falkenburg, Mirjam H M Heemskerk
TCR targeting hematopoiesis to cure leukemia. Blood 144 (10) (2024)
Margaretha L M Prins, Geert V T Roozen, Cilia R Pothast, Wesley Huisman, Rob van Binnendijk, Gerco den Hartog, Vincent P Kuiper, Corine Prins, Jacqueline J Janse, Olivia A C Lamers, Jan Pieter R Koopman, Annelieke C Kruithof, Ingrid M C Kamerling, Romy C Dijkland, Alicia C de Kroon, Shohreh Azimi, Mariet C W Feltkamp, Marjan Kuijer, Simon P Jochems, Mirjam H M Heemskerk, Frits Richard Rosendaal, Meta Roestenberg, Leo G Visser, Anna H E Roukens
Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial. NPJ vaccines 9 (1) (2024)
Tassilo L A Wachsmann, Miranda H Meeuwsen, Dennis F G Remst, Karen Buchner, Anne K Wouters, Renate Hagedoorn, J H Frederik Falkenburg, Mirjam H M Heemskerk
Combining BCMA-targeting CAR-T with TCR-engineered T-cell therapy to prevent immune escape of multiple myeloma. Blood advances (2023)
Jesper van Eck van der Sluijs, Diede van Ens, Jolanda Brummelman, Daan Heister, Aastha Sareen, Lisa Truijen, Dorette S van Ingen Schenau, Mirjam H M Heemskerk, Marieke Griffioen, Michel G D Kester, Nicolaas P M Schaap, Joop H Jansen, Anniek B van der Waart, Harry Dolstra, Willemijn Hobo
Human CD34 + -derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8 + T cell and NK cell responses in vitro and in vivo. Cellular and molecular life sciences : CMLS 80 (10) (2023)
Ilse Gille, Renate S Hagedoorn, Ellen M W van der Meer-Prins, Mirjam H M Heemskerk, Sebastiaan Heidt
Chimeric HLA antibody receptor T cells to target HLA-specific B cells in solid organ transplantation. HLA (2023)
Ruud H Wijdeven, Sietse J Luk, Tom A W Schoufour, Sabina Y van der Zanden, Marta Cabezuelo, Mirjam H M Heemskerk, Jacques J C Neefjes
Balanced Epigenetic Regulation of MHC Class I Expression in Tumor Cells by the Histone Ubiquitin Modifiers BAP1 and PCGF1. Journal of immunology (Baltimore, Md. : 1950) (2023)
Jessie S Kroonen, Ilona J de Graaf, Sumit Kumar, Dennis F G Remst, Anne K Wouters, Mirjam H M Heemskerk, Alfred C O Vertegaal
Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies. Leukemia (2023)
Willemijn van der Wulp, Dennis F G Remst, Michel G D Kester, Renate S Hagedoorn, Paul W H I Parren, Sander I van Kasteren, Janine Schuurman, Wytske M van Weerden, Maaike E Ressing, Boris Bleijlevens, Mirjam H M Heemskerk
Antibody-mediated delivery of viral epitopes to redirect EBV-specific CD8 + T-cell immunity towards cancer cells. Cancer gene therapy (2023)
Sietse J Luk, Rouven Schoppmeyer, Marieke E Ijsselsteijn, Antonios Somarakis, Ibtissam Acem, Dennis F G Remst, Daan T Cox, Cornelis A M van Bergen, Inge H Briaire-de Bruijn, Max L B Grönloh, Werner J van der Meer, Lukas J A C Hawinkels, Roman I Koning, Erik Bos, Judith V M G Bovée, Noel F C C de Miranda, Károly Szuhai, Jaap Diederik van Buul, J H Frederik Falkenburg, Mirjam H M Heemskerk
VISTA expression on cancer-associated endothelium selectively prevents T-cell extravasation. Cancer immunology research (2023)
Miranda H Meeuwsen, Anne K Wouters, Renate S Hagedoorn, Michel G D Kester, Dennis F G Remst, Dirk M van der Steen, Arnoud de Ru, Peter A van Veelen, Jamie Rossjohn, Stephanie Gras, J H Frederik Falkenburg, Mirjam H M Heemskerk
Cutting Edge: Unconventional CD8 + T Cell Recognition of a Naturally Occurring HLA-A*02:01-Restricted 20mer Epitope. Journal of immunology (Baltimore, Md. : 1950) 208 (8) (2022)
Tassilo L A Wachsmann, Anne K Wouters, Dennis F G Remst, Renate S Hagedoorn, Miranda H Meeuwsen, Eline van Diest, Jeanette H W Leusen, Jürgen H E Kuball, J H Frederik Falkenburg, Mirjam H M Heemskerk
Comparing CAR and TCR engineered T cell performance as a function of tumor cell exposure. Oncoimmunology 11 (1) (2022)
Cilia R Pothast, Kayleigh van Dijk, Emma S Pool, Constantijn Jm Jm Halkes, Mirjam H M Heemskerk, Jennifer M-L Tjon
SARS-CoV-2 mRNA vaccination of aplastic anemia patients is safe and effective. American journal of hematology (2022)
Sabine Haggenburg, Birgit I Lissenberg-Witte, Robert S van Binnendijk, Gerco den Hartog, Michel S Bhoekhan, Nienke J E Haverkate, Dennis M de Rooij, Johan van Meerloo, Jacqueline Cloos, Neeltje A Kootstra, Dorine Wouters, Suzanne S Weijers, Ester M M van Leeuwen, Esther J Nossent, Saïda Tonouh-Aajoud, Mirjam H M Heemskerk, Rogier W Sanders, Elianne Roelandse-Koop, Quincy Hofsink, Kazimierz Groen, Lucia Çetinel, Louis Schellekens, Yvonne M den Hartog, Belle Toussaint, Iris M J Kant, Thecla Graas, Emma de Pater, Willem A Dik, Marije D Engel, Cheyenne R N Pierie, Suzanne R Janssen, Edith van Dijkman, Meliawati Poniman, Judith A Burger, Joey H Bouhuijs, Gaby Smits, Nynke Y Rots, Sonja Zweegman, Arnon P Kater, Tom van Meerten, Pim G N J Mutsaers, Jaap A van Doesum, Annoek E C Broers, Marit J VAN Gils, Abraham Goorhuis, Caroline E Rutten, Mette D Hazenberg, Inger S Nijhof
Quantitative analysis of mRNA-1273 COVID-19 vaccination response in immunocompromised adult hematology patients. Blood advances 6 (5) (2022)
Rosa A van Amerongen, Renate S Hagedoorn, Dennis F G Remst, Danique C Assendelft, Dirk M van der Steen, Anne K Wouters, Marian van de Meent, Michel G D Kester, Arnoud H de Ru, Marieke Griffioen, Peter A van Veelen, J H Frederik Falkenburg, Mirjam H M Heemskerk
WT1-specific TCRs directed against newly identified peptides install antitumor reactivity against acute myeloid leukemia and ovarian carcinoma. Journal for immunotherapy of cancer 10 (6) (2022)
Laura T Morton, Tassilo L A Wachsmann, Miranda H Meeuwsen, Anne K Wouters, Dennis F G Remst, Marleen M van Loenen, J H Frederik Falkenburg, Mirjam H M Heemskerk
T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion. Journal for immunotherapy of cancer 10 (3) (2022)
Nathalie M Schmidt, Peter A C Wing, Mariana O Diniz, Laura J Pallett, Leo Swadling, James Michael Harris, Alice R Burton, Anna Jeffery-Smith, Nekisa Zakeri, Oliver E Amin, Stephanie Kucykowicz, Mirjam H M Heemskerk, Brian Davidson, Tim Meyer, Joe Grove, Hans J Stauss, Inés Pineda-Torra, Clare Jolly, Elizabeth C Jury, Jane A McKeating, Mala K Maini
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint. Nature communications 12 (1) (2021)
Jesper van Eck van der Sluijs, Diede van Ens, Soley Thordardottir, Denise Vodegel, Inge A T Hermens, Anniek B van der Waart, J H Frederik Falkenburg, Michel G D Kester, Iris de Rink, Mirjam H M Heemskerk, Jannie Borst, Nicolaas P M Schaap, Joop H Jansen, Yanling Xiao, Harry Dolstra, Willemijn Hobo
Clinically applicable CD34+-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses. Cancer immunology, immunotherapy : CII 70 (11) (2021)
Dyantha I van der Lee, Georgia Koutsoumpli, Rogier M Reijmers, Willy Honders, Rob C M de Jong, Dennis F G Remst, Tassilo L A Wachsmann, Renate S Hagedoorn, Kees L M C Franken, Michel G D Kester, Karl J Harber, Lisanne M Roelofsen, Annemiek M Schouten, Arend Mulder, Jan Wouter Drijfhout, Hendrik Veelken, Peter A van Veelen, Mirjam H M Heemskerk, Frederik Falkenburg, Marieke Griffioen
An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML. Cancers 13 (21) (2021)
Anna H E Roukens, Cilia R Pothast, Marion H König, Wesley Huisman, Tim J Dalebout, Tamar Tak, Shohreh Azimi, Yvonne Kruize, Renate S Hagedoorn, Mihaela Zlei, Frank J T Staal, Fenna J de Bie, Jacques J M van Dongen, Sesmu M Arbous, Jaimie L H Zhang, Maaike Verheij, Corine Prins, Anne M van der Does, Pieter S Hiemstra, Jutte J C de Vries, Jacqueline J Janse, Meta Roestenberg, Sebenzile K Myeni, Marjolein Kikkert, Maria M Yazdanbakhsh, Mirjam H M Heemskerk, Hermelijn H Smits, Simon P Jochems, null null, null null
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8 + T cell responses following COVID-19. Nature immunology 23 (1) (2021)
Peter van Balen, Michel G D Kester, Wendy de Klerk, Pietro Crivello, Esteban Arrieta-Bolaños, Arnoud H de Ru, Inge Jedema, Yassene Mohammed, Mirjam H M Heemskerk, Katharina Fleischhauer, Peter A van Veelen, J H Frederik Falkenburg
Immunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies. Journal of immunology (Baltimore, Md. : 1950) 204 (12) (2020)
Paula Ruibal, Kees L M C Franken, Krista E van Meijgaarden, Joeri J F van Loon, Dirk van der Steen, Mirjam H M Heemskerk, Tom H M Ottenhoff, Simone A Joosten
Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues. Journal of immunology (Baltimore, Md. : 1950) 205 (10) (2020)
Sharyn Thomas, Fiyaz Mohammed, Rogier M Reijmers, Annemarie L Woolston, Theresa Stauss, Alan Kennedy, David R Stirling, Angelika Holler, Louisa Green, David T Jones, Katherine K Matthews, David A Price, Benjamin M Chain, Mirjam H M Heemskerk, Emma Catherine Morris, Benjamin E Willcox, Hans J Stauss
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function. Nature communications 10 (1) (2019)
Koen A Marijt, Laura Blijleven, Elizabeth M E Verdegaal, Michel G Kester, Daniel J Kowalewski, Hans-Georg Rammensee, Stefan Stevanovic, Mirjam H M Heemskerk, Sjoerd H Van der Burg, Thorbald van Hall
Identification of non-mutated neoantigens presented by TAP-deficient tumors. The Journal of experimental medicine 215 (9) (2018)
Tim J A Hutten, Soley Thordardottir, Hanny Fredrix, Lisanne Janssen, Rob Woestenenk, Jurjen Tel, Ben Joosten, Alessandra Cambi, Mirjam H M Heemskerk, Gerben M Franssen, Otto C Boerman, Lex B H Bakker, Joop H Jansen, Nicolaas P M Schaap, Harry Dolstra, Willemijn Hobo
CLEC12A-Mediated Antigen Uptake and Cross-Presentation by Human Dendritic Cell Subsets Efficiently Boost Tumor-Reactive T Cell Responses. Journal of immunology (Baltimore, Md. : 1950) 197 (7) (2016)

Mirjam H M Heemskerk.css-eqlu8i{font-size:small;padding-left:4px;} (Mirjam H Heemskerk)

Publication Activity (10 Years)

Top Topics

Top Venues

Mirjam H M Heemskerk (Mirjam H Heemskerk)