Brian B Liau

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 27

Top Topics

Acute Myeloid Leukemia

Transcription Factor

Dna Methylation

Top Venues

Nature chemical biology

Nature communications

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Megan Jin Rae Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, Neil Connor Payne, Pallavi M Gosavi, Hui Si Kwok, Irtiza Iram, Ceejay Lee, Jiaming Li, Nicholas J Chen, Hanjie Jiang, Zhipeng A Wang, Kwangwoon Lee, Haibin Mao, Stefan Andrew Harry, Idris A Barakat, Mariko Takahashi, Amanda L Waterbury, Marco Barone, Andrea Mattevi, Liron Bar-Peled, Philip A Cole, Ralph Mazitschek, Brian B Liau, Ning Zheng
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. bioRxiv : the preprint server for biology (2024)
Xiaowen Xie, Olivia Zhang, Megan Jin Rae Yeo, Ceejay Lee, Stefan Andrew Harry, Leena Paul, Yiran Li, Neil Connor Payne, Eunju Nam, Hui Si Kwok, Hanjie Jiang, Haibin Mao, Jennifer L Hadley, Hong Lin, Melissa Batts, Pallavi M Gosavi, Vincenzo D'Angiolella, Philip A Cole, Ralph Mazitschek, Paul A Northcott, Ning Zheng, Brian B Liau
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. bioRxiv : the preprint server for biology (2024)
Fadi J Najm, Peter C DeWeirdt, Molly M Moore, Samantha M Bevill, Chadi A El Farran, Kevin A Macias, Mudra Hegde, Amanda L Waterbury, Brian B Liau, Peter van Galen, John G Doench, Bradley E Bernstein
Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications 14 (1) (2023)
Fadi J Najm, Peter C DeWeirdt, Molly M Moore, Samantha M Bevill, Chadi A El Farran, Kevin A Macias, Mudra Hegde, Amanda L Waterbury, Brian B Liau, Peter van Galen, John G Doench, Bradley E Bernstein
Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications 14 (1) (2023)
Fadi J Najm, Peter C DeWeirdt, Molly M Moore, Samantha M Bevill, Chadi A El Farran, Kevin A Macias, Mudra Hegde, Amanda L Waterbury, Brian B Liau, Peter van Galen, John G Doench, Bradley E Bernstein
Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications 14 (1) (2023)
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife 12 (2023)
Fadi J Najm, Peter C DeWeirdt, Molly M Moore, Samantha M Bevill, Chadi A El Farran, Kevin A Macias, Mudra Hegde, Amanda L Waterbury, Brian B Liau, Peter van Galen, John G Doench, Bradley E Bernstein
Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications 14 (1) (2023)
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife 12 (2023)
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife 12 (2023)
Fadi J Najm, Peter C DeWeirdt, Molly M Moore, Samantha M Bevill, Chadi A El Farran, Kevin A Macias, Mudra Hegde, Amanda L Waterbury, Brian B Liau, Peter van Galen, John G Doench, Bradley E Bernstein
Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications 14 (1) (2023)
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife 12 (2023)
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife 12 (2023)
Fadi J Najm, Peter C DeWeirdt, Molly M Moore, Samantha M Bevill, Chadi A El Farran, Kevin A Macias, Mudra Hegde, Amanda L Waterbury, Brian B Liau, Peter van Galen, John G Doench, Bradley E Bernstein
Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications 14 (1) (2023)
Emma M Garcia, Nicholas Z Lue, Jessica K Liang, Whitney K Lieberman, Derek D Hwang, James C Woods, Brian B Liau
Base Editor Scanning Reveals Activating Mutations of DNMT3A. ACS chemical biology (2023)
Hui Si Kwok, Allyson M Freedy, Allison P Siegenfeld, Julia W Morriss, Amanda L Waterbury, Stephen M Kissler, Brian B Liau
Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma. Nature chemical biology (2023)
Allison P Siegenfeld, Shelby A Roseman, Heejin Roh, Nicholas Z Lue, Corin C Wagen, Eric Zhou, Sarah E Johnstone, Martin J Aryee, Brian B Liau
Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery. Nature communications 13 (1) (2022)
Nicholas Z Lue, Emma M Garcia, Kevin Chun-Ho Ngan, Ceejay Lee, John G Doench, Brian B Liau
Base editor scanning charts the DNMT3A activity landscape. Nature chemical biology (2022)
Pallavi M Gosavi, Kevin Chun-Ho Ngan, Megan Jin Rae Yeo, Cindy Su, Jiaming Li, Nicholas Z Lue, Samuel M Hoenig, Brian B Liau
Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders. ACS central science 8 (4) (2022)
Yumi Koga, Eileen M Hoang, Yongho Park, Alexander F A Keszei, Jason Murray, Sichen Shao, Brian B Liau
Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. Journal of the American Chemical Society 143 (34) (2021)
Allyson M Freedy, Brian B Liau
Discovering new biology with drug-resistance alleles. Nature chemical biology 17 (12) (2021)
Yongho Park, Yumi Koga, Cindy Su, Amanda L Waterbury, Christopher L Johnny, Brian B Liau
Versatile Synthetic Route to Cycloheximide and Analogues That Potently Inhibit Translation Elongation. Angewandte Chemie (International ed. in English) 58 (16) (2019)
Michael E Vinyard, Cindy Su, Allison P Siegenfeld, Amanda L Waterbury, Allyson M Freedy, Pallavi M Gosavi, Yongho Park, Eugene E Kwan, Benjamin D Senzer, John G Doench, Daniel E Bauer, Luca Pinello, Brian B Liau
CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nature chemical biology 15 (5) (2019)
Allison P Siegenfeld, Ceejay Lee, Brian B Liau
Taking a STAP at Core Promoter-Transcriptional Cofactor Specificity. Biochemistry 58 (29) (2019)